368 research outputs found
Archaeological Survey Of The Los Rios Clubhouse Area Collin County, Texas
The City of Plano is proposing to convert the Los Rios Golf Course and Country Club into a city park. For the first phase of the project, the city may choose to remove the clubhouse and associated physical facilities. The City of Plano contracted with AR Consultants, Inc. to conduct an archaeological survey of the 8.3-acre area surrounding the clubhouse and an architectural evaluation of the clubhouse. Of the 8.3 acres, six are paved or are the sites of buildings. The archaeological survey, which was conducted under the authority of Texas Antiquities Permit 8283, was conducted on January 12, 2018 and focused only on the unpaved areas. No prehistoric cultural remains were found. A few isolated historic artifacts were found on the surface but were not determined to be a site. The architectural evaluation determined that the clubhouse may be significant based on its connection to local entertainment/recreation, its example as a Modern-style clubhouse, and its connection to the Craycroft-Lacy & Partners architectural firm. However, the clubhouse is not yet 50 years old. Therefore, it is not recommended eligible for listing on the National Register of Historic Places or for designation as a State Antiquities Landmark. Given the results of this survey, AR Consultants, Inc. recommends that further cultural resource investigations are unnecessary within the 8.3-acre project area surrounding the clubhouse, and requests that the Texas Historical Commission concur with this recommendation. Documents related to the archaeological survey will be curated at the Center for Archaeological Studies at Texas State University in San Marcos
Henry Miller’s Tropic of Cancer: The Local Connection (SCRC Behind the Scenes)
This entry discusses the censorship of Henry Miller\u27s Tropic of Cancer in Syracuse, N
Altruistic Argument in the Demand-Withdraw Pattern in Interpersonal Disputes
The demand-withdraw pattern in interpersonal disputes is associated with negative outcomes. Yet altruistic argument, viewed as prosocial evidence and reasoning, may affect the demand-withdraw pattern. Using multiple goals communication theory, multiple goal perceptions are hypothesized to mediate the relationship between two pattern types (using/not using altruistic argument), and interaction outcomes. US young adults (N=322) evaluated an interaction that varied in pattern type and relationship type. Mediation analyses confirmed the three hypotheses
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Responsiveness of PROMIS® to change in chronic obstructive pulmonary disease.
BackgroundChronic obstructive pulmonary disease (COPD) is a progressive chronic disease characterized by airflow obstruction that leads to shortness of breath and substantial negative impacts on health-related quality of life (HRQL). The course of COPD includes periodic acute exacerbations that require changes in treatment and/or hospitalizations. This study was designed to examine the responsiveness of Patient-Reported Outcomes Measurement Information System® (PROMIS®) measures to changes associated with COPD exacerbation recovery.MethodsA longitudinal analysis using mixed-effects models was conducted of people who were enrolled while stable (n = 100) and those who experienced an acute exacerbation (n = 85). PROMIS (physical function, pain interference, pain behavior, fatigue, anxiety, depression, anger, social roles, discretionary social activities, Global Health, dyspnea severity and dyspnea functional limitations) and COPD-targeted HRQL measures were completed at baseline and at 12 weeks.ResultsWe administered PROMIS measures using computer adaptive testing (CAT), followed by administration of any remaining short form (SF) items that had not yet been administered by CAT. Examination of the difference between group differences from baseline to 12 weeks in the stable and exacerbation groups revealed that the exacerbation group changed (improved) significantly more than the stable group in anxiety (p < .001 to p < .01; f2 effect size [ES] = 0.023/0.021), fatigue (p < .0001; ES = 0.036/0.047) and social roles (p < .001 to p < .05; ES = 0.035/0.024). All effect sizes were small in magnitude and smaller than hypothesized. Depression was also statistically significant (p < .05, SF only) but the ES was trivial. For all other PROMIS domains, the differences were not significant and ES were trivial.ConclusionsThis longitudinal study provides some support for the validity of the PROMIS fatigue, anxiety, and social roles domains in COPD, but further evaluation of responsiveness is warranted
Chronicles of Oklahoma
Article describes Oklahoma-born architect William Wayne Caudill's career and his contributions to architecture in Oklahoma
The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation
During cell division, kinetochores form the primary chromosomal attachment sites for spindle microtubules. We previously identified a network of 10 interacting kinetochore proteins conserved between Caenorhabditis elegans and humans. In this study, we investigate three proteins in the human network (hDsn1Q9H410, hNnf1PMF1, and hNsl1DC31). Using coexpression in bacteria and fractionation of mitotic extracts, we demonstrate that these proteins form a stable complex with the conserved kinetochore component hMis12. Human or chicken cells depleted of Mis12 complex subunits are delayed in mitosis with misaligned chromosomes and defects in chromosome biorientation. Aligned chromosomes exhibited reduced centromere stretch and diminished kinetochore microtubule bundles. Consistent with this, localization of the outer plate constituent Ndc80HEC1 was severely reduced. The checkpoint protein BubR1, the fibrous corona component centromere protein (CENP) E, and the inner kinetochore proteins CENP-A and CENP-H also failed to accumulate to wild-type levels in depleted cells. These results indicate that a four-subunit Mis12 complex plays an essential role in chromosome segregation in vertebrates and contributes to mitotic kinetochore assembly
Evidence That the Clinical Impairment Assessment (CIA) Subscales Should Not Be Scored: Bifactor Modelling, Reliability, and Validity in Clinical and Community Samples
Aim: The Clinical Impairment Assessment (CIA 3.0) is the most widely used instrument assessing psychosocial impairment secondary to eating disorder symptoms. However, there is conflicting advice regarding the dimensionality and optimal method of scoring the CIA. We sought to resolve this confusion by conducting a comprehensive factor analytic study of the CIA in a community sample (N = 301) and clinical sample comprising patients with a diagnosed eating disorder (N = 209). Convergent and discriminant validity were also assessed. Method: The CIA and measures of eating disorder symptoms were administered to both samples. Results: Factor analyses indicated there is a general impairment factor underlying all items on the CIA that is reliably measured by the CIA Global score. CIA Global demonstrated good convergent and discriminant validity. Conclusions: CIA Global is a reliable and valid measure of psychosocial impairment secondary to eating disorder symptoms; however, subscale scores should not be computed
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