4,296 research outputs found
Globalization or Localization? A longitudinal study of successful American and Chinese online store websites
This paper reports the results of a longitudinal study of 2562 images on the homepages of successful American and Chinese online store websites,with the goal of determining whether cultural factors impact their visual presentation and evolution. Descriptive and statistical content analyses reveal that the U.S. and Chinese online store sites showed significant cross-national image differences from their inception; moreover, the Chinese sites diverged further from the U.S. sites over time, strengthening their own cultural identity and suggesting a trend towards localization in a diverse and dynamic world market. These findings support the view that although English-speaking Western culture is widespread in today’s Information Age, other cultures are not necessarily undermined
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What Women With Disabilities Write in Personal Blogs About Pregnancy and Early Motherhood: Qualitative Analysis of Blogs.
BackgroundMore than 1 in 10 women of reproductive age identify as having some type of disability. Most of these women are able to become pregnant and have similar desires for motherhood as women without disability. Women with disability, however, face greater stigma and stereotyping, additional risk factors, and may be less likely to receive adequate reproductive health care compared with their peers without disability. More and more individuals, including those with disability, are utilizing the internet to seek information and peer support. Blogs are one source of peer-to-peer social media engagement that may provide a forum for women with disability to both share and obtain peer-to-peer information and support. Nevertheless, it is not clear what content about reproductive health and pregnancy and/or motherhood is featured in personal blogs authored by women with spinal cord injury (SCI), traumatic brain injury (TBI), spina bifida, and autism.ObjectiveThe objective of this study was twofold: (1) to examine the information being shared in blogs by women with 4 types of disabilities, namely, SCI, TBI, spina bifida, and autism, about reproductive health, disability, health care, pregnancy, and motherhood; and (2) to classify the content of reproductive health experiences addressed by bloggers to better understand what they viewed as important.MethodsPersonal blogs were identified by searching Google with keywords related to disabilities, SCI, TBI, spina bifida, and autism, and a variety of keywords related to reproductive health. The first 10 pages of each database search in Google, based on the relevance of the search terms, were reviewed and all blogs in these pages were included. Blog inclusion criteria were as follows: (1) written by a woman or care partner (ie, parent or spouse) of a woman with a self-identified diagnosis of SCI, TBI, spina bifida, or autism; (2) focused on the personal experience of health and health care during the prepregnancy, prenatal, antepartum, intrapartum, and/or postpartum periods; (3) written in English; and (4) published between 2013 and 2017. A descriptive and thematic qualitative analysis of blogs and corresponding comments was facilitated with NVivo software and matrix analysis.ResultsOur search strategy identified 125 blogs that met all the inclusion criteria; no blogs written by women with spina bifida were identified. We identified 4 reproductive health themes featured in the blog of women with disabilities: (1) (in)accessible motherhood, (2) (un)supportive others, (3) different, but not different, and (4) society questioning motherhood.ConclusionsThis analysis of personal blogs about pregnancy and health care written by women with SCI, TBI, and autism provides a glimpse into their experiences. The challenges faced by these women and the adaptations they made to successfully navigate pregnancy and early motherhood provide insights that can be used to shape future research
Perioperative melatonin secretion in patients undergoing coronary artery bypass grafting.
UNLABELLED: Melatonin, a neurohormone, plays an important role in adjusting the "biological clock" in humans. We sought to describe perioperative patterns of melatonin secretion in patients undergoing coronary artery bypass grafting surgery with cardiopulmonary bypass (CPB). After IRB approval and written informed consent, 12 male patients scheduled for elective coronary artery bypass grafting under hypothermic CPB were enrolled in the study. During anesthesia, patients' eyes were carefully covered to prevent light effects. Blood samples were taken at specific time points during surgery, every 3 h in the immediate postoperative period, and for 24 h from 6:00 PM of Postoperative Day 2 until 6:00 PM of Postoperative Day 3. Plasma melatonin and cortisol concentrations were measured by radioimmunoassay and enzyme-linked immunosorbent assay, respectively. During surgery, plasma melatonin concentrations were below the minimum sensitivity concentration, yet small concentrations, without circadian variation, were detected during the immediate postoperative period. During Postoperative Days 2 and 3, circadian secretion patterns of melatonin were present in 10 patients and showed an inverse correlation with light intensity (r = 0.480; P < 0.01). Plasma cortisol concentrations in the immediate postoperative period were significantly larger than those before the induction of anesthesia (P < 0.01). Only three patients regained circadian secretion of cortisol. We concluded that melatonin and cortisol secretion was disrupted during cardiac surgery with CPB and in the immediate postoperative period. However, circadian rhythms of melatonin were present in most patients from Postoperative Day 2. Only 30% of the patients regained circadian rhythm of cortisol secretion. IMPLICATIONS: Melatonin is a hormone that plays an important role in adjusting the biological clock in humans and that regulates secretion of various other hormones. We studied melatonin secretion in patients undergoing cardiac surgery with cardiopulmonary bypass. Melatonin secretion was disturbed during and immediately after surgery but had recovered a circadian rhythm 24 h later, raising the question of whether melatonin should be supplemented before cardiac surgery
Development and evaluation of the Dignity Talk question framework for palliative patients and their families: A mixed-methods study
Background:
Effective patient–family communication can reduce patients’ psychosocial distress and relieve family members’ current suffering and their subsequent grief. However, terminally ill patients and their family members often experience great difficulty in communicating their true feelings, concerns, and needs to each other.
Aim:
To develop a novel means of facilitating meaningful conversations for palliative patients and family members, coined Dignity Talk, explore anticipated benefits and challenges of using Dignity Talk, and solicit suggestions for protocol improvement.
Design:
A convergent parallel mixed-methods design. Dignity Talk, a self-administered question list, was designed to prompt end-of-life conversations, adapted from the Dignity Therapy question framework. Participants were surveyed to evaluate the Dignity Talk question framework. Data were analyzed using qualitative and quantitative methods.
Setting/participants:
A total of 20 palliative patients, 20 family members, and 34 healthcare providers were recruited from two inpatient palliative care units in Winnipeg, Canada.
Results:
Most Dignity Talk questions were endorsed by the majority of patients and families (>70%). Dignity Talk was revised to be convenient and flexible to use, broadly accessible, clearly stated, and sensitively worded. Participants felt Dignity Talk would be valuable in promoting conversations, enhancing family connections and relationships, enhancing patient sense of value and dignity, promoting effective interaction, and attending to unfinished business. Participants suggested that patients and family members be given latitude to respond only to questions that are meaningful to them and within their emotional capacity to broach.
Conclusion:
Dignity Talk may provide a gentle means of facilitating important end-of-life conversations
The Potential for Oysters, Crassostrea Virginica, to Develop Resistance to Dermo Disease in the Field: Evaluation Using a Gene-Based Population Dynamics Model
Today, populations of eastern oysters, Crassostrea virginica, are commonly limited by disease mortality. Resistance to MSX disease has developed in a number of cases, but the development of resistance to Dermo disease would appear to be limited, despite the high mortality rates and frequency of epizootics. Can aspects of the host\u27s genetics or population dynamics limit the response to the disease despite the apparent opportunity afforded by alleles conferring disease resistance or tolerance? To answer this question, we use a gene-based population dynamics model, configured for C. virginica, to simulate the development of disease resistance using mortality as the agent of selection. Simulated populations were exposed to 4 levels of mortality covering the range in mortality observed in Delaware Bay in the l990s. In each case, disease resistance increased in the simulated population over time, normally proportional to the increase in mortality rate imposed by the disease. However, simulations show that the population responds even at its most rapid rate on multidecadal to half-century timescales. As the mortality rate declines with increasing disease resistance, the rate of further improvement in disease resistance likewise declines. Thus, disease resistance develops over decadal timescales at a 40%-per-year mortality rate, but, as mortality rate falls to 25% per year, the rate of further development of disease resistance extends to half-century timescales. The discouraging profundity is that a mortality rate of 25% per year, yielding a rate of selection profoundly slow, is still very high. In northern climes, significant decrements in oyster abundance will occur. Evidence from fisheries retrospectives suggests that oysters cannot withstand a constant removal at this scale without compromising population integrity noticeably. So, a mortality rate that grievously limits the development of disease resistance still sorely strains the species\u27 ability to maintain a vibrant population necessary to its long-term survival
Qualitative Evaluation of High School Implementation Strategies for Youth Sports Concussion Laws
Context: All 50 states and the District of Columbia have enacted laws governing concussion management and education. These concussion laws, featuring common tenets regarding removal from play, return to play, and concussion education, have shaped school and district policies.
Objective: To evaluate the strategies commonly used to implement concussion laws at the school and district levels, as reported by certified athletic trainers (ATs).
Design: Qualitative study.
Setting: High schools.
Patients or Other Participants: We interviewed 64 ATs from high schools (1 per school) participating in High School Reporting Information Online.
Data Collection and Analysis: Interviews were conducted with participants between April and October 2015 regarding implementation of the 3 core tenets of concussion laws. Research team members independently evaluated the interview transcripts and field notes to identify common themes in implementation strategies.
Results: Of the 64 schools represented, 90.6% were public schools, 89.1% sponsored more than 15 sports, and all schools employed at least 1 AT and had a written concussion policy. Four commonly used strategies to implement removal from play were reliance on coaches, immediate response, referral and guidance after injury, and notification of key individuals. Use of assessment or baseline tests, communication among parties involved, reliance on AT assessments, and return-to-learn policies were 4 frequent strategies to implement return to play. Finally, 3 major implementation strategies to effectuate concussion education were use of existing educational tools, timing of education, and concussion training for school professionals.
Conclusions: Although concussion laws were passed at different times and varied in content across states, common themes in implementation strategies emerged across jurisdictions. The identification of strategic approaches to implementation will help ensure proper concussion management and education, reducing negative health outcomes among youths with concussions
Crimson: A Data Management System to Support Evaluating Phylogenetic Tree Reconstruction Algorithms
Evolutionary and systems biology increasingly rely on the construction of large phylogenetic trees which represent the relationships between species of interest. As the number and size of such trees increases, so does the need for efficient data storage and query capabilities. Although much attention has been focused on XML as a tree data model, phylogenetic trees differ from document-oriented applications in their size and depth, and their need for structure based queries rather than path-based queries.
This paper focuses on Crimson, a tree storage system for phylogenetic trees used to evaluate phylogenetic tree reconstruction algorithms within the context of the NSF CIPRes project. A goal of the modeling component of the CIPRes project is to construct a huge simulation tree representing a gold standard of evolutionary history against which phylogenetic tree reconstruction algorithms can be tested.
In this demonstration, we highlight our storage and indexing strategies and show how Crimson is used for benchmarking phylogenetic tree reconstruction algorithms. We also show how our design can be used to support more general queries over phylogenetic trees
Reducing job insecurity and increasing performance ratings: Does impression management matter?
Prior research on job insecurity has demonstrated its detrimental effects on both employees and the organization, yet no research has detailed how people actively deal with it. Drawing from proactivity research, this article argues that job insecurity prompts a proactive use of impression management tactics in the workplace. The effectiveness of these tactics depends on the level of supervisory liking for the employee and the attributions supervisors make regarding the employee's motives for the impression management behaviors (i.e., for the good of the organization or for self-interest). A 3-wave survey study of 271 Chinese employees and their supervisors showed that employees experiencing job insecurity in Time 1 reported using a variety of tactics to impress their supervisors at Time 2 and that these tactics curbed the affect associated with job insecurity and enhanced supervisor rated performance, through supervisor's liking and attributed motives. The relationship between impression management and increased supervisor-rated performance was moderated by supervisor attributions; the relationship between impression management and reduced affective job insecurity depended on supervisor liking. © 2013 American Psychological Association.postprin
Effective population sizes of eastern oyster Crassostrea virginica (Gmelin) populations in Delaware Bay, USA
Effective population size (Ne) is an important concept in population genetics as it dictates the rate of genetic change caused by drift. Ne estimates for many marine populations are small relative to the census population size. Small Ne in a large population may indicate high reproductive variance or sweepstakes reproductive success (SRS). The eastern oyster (Crassostrea virginica) may be prone to SRS due to its high fecundity and high larval mortality. To examine if SRS occurs in the eastern oyster, we studied Ne and genetic variation of oyster populations in Delaware Bay. Adult and spat oysters were collected from five locations in different years and genotyped with seven microsatellite markers. Slight genetic differences were revealed by Fst statistics between the adult populations and spat recruits, while the adult populations are spatially homogeneous and temporally stable. Comparisons of genetic diversity and relatedness among adult and spat samples failed to provide convincing evidence for strong SRS. Ne estimates obtained with five different methods were variable, small and often without upper confidence limits. For single sample collections, Ne estimates for spat (140–440) were consistently smaller than that for adults (589–2,779). Analysis of pooled adult samples across all sites suggests that Ne for the whole bay may be very large, as indicated by the large point estimates and the lack of upper confidence limits. These results suggest that Ne may be small for a given spat fall, but the entire adult population may have large Ne and is temporally stable as it is the accumulation of many spat falls per year over many year
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