9 research outputs found
Within-season changes in habitat use of forest-dwelling boreal bats
- Author
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Bats utilize forests as roosting sites and feeding areas. However, it has not been documented how bats utilize these habitats in the boreal zone with methods afforded by recent technological advances. Forest structure and management practices can create a variety of three-dimensional habitats for organisms capable of flight, such as bats. Here, we study the presence of boreal bats in a forest forming a mosaic of different age classes, dominant tree species, canopy cover, soil fertility, and other environmental variables, throughout their active season in the summer using passive ultrasound detectors. Our results indicate a preference for mature forest by Eptesicus nilssonii and a pooled set of Myotis bats. Both groups of bats also showed temporal changes in their habitat use regarding forest age. In June and July, both groups occurred more often in mature than young forests, but from August onwards, the difference in occurrence became less evident in Myotis and disappeared completely in E. nilssonii. In addition, E. nilssonii was more often present in forests with low canopy cover, and its occurrence shifted from coniferous forests to deciduous forests during the season. The results reflect the within-season dynamics of bat communities and their ability to utilize different types of forest as environmental conditions change. Yet, the results most importantly emphasize the importance of mature forests to bat diversity and the need to conserve such environments in the boreal zone.Peer reviewe
New insights into the genetic etiology of Alzheimer's disease and related dementias
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- Aarsland Dag
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- SĂĄnchez-Arjona M.B.
- SĂĄnchez-Valle R.
- Takalo M.
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- Teipel S.
- Teng E.
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- Thalamuthu A.
- Thomas A.
- Thomas C.
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- Tsai E.
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- Tuovila O.
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- TybjĂŠrg-Hansen A.
- Tzourio C.
- TĂĄrraga L.
- Uitterlinden A.
- Ullgren A.
- Ulstein I.
- Universitat AutĂČnoma de Barcelona
- Uphill J.
- Usiskin K.
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- Vacca A.
- Vainio S.
- Valero S.
- Valladares O.
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- van Adelsberg J.
- Van Deerlin V.M.
- van den Bussche H.
- van der Flier Wiesje M
- van der Lee S.J.
- van der Lugt A.
- van Duijn C.M.
- van Eldik L.J.
- van Lent D.M.
- van Rooij J.
- van Swieten J.
- Vance J.
- Vandenberghe R.
- Vardarajan B.N.
- Vardy E.
- Vargas L.
- Vassar R.
- Verhey F.
- Vicente M. P.
- Vidal J.S.
- Vigo-Ortega R.
- Vigo-Ortega R.
- Vilas R.H.
- Vinters H.V.
- Virolainen P.
- Vivancos L.
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- Vonsattel J.P.
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- Wang C.
- Wang L.S.
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- Warden D.
- Waring J.
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- Waterworth D.
- Weber H.
- Weinhold L.
- Weinstein G.
- Weintraub S.
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- Wilcock G.
- Wilhelmsen K.C.
- Williams A.
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- Williamson J.
- Wilms H.
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- Windle G.
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- Wisniewski T.
- Wittfeld K.
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- Wong R.
- Woods B.
- Woon M.
- Wright C.B.
- Wu C.K.
- Wu Y.
- Xia T.h.
- Xu E.
- Xu F.
- Yanek L.
- Yang Q.
- Yang Y.
- Yannakoulia M.
- Yaqub A.
- Younkin S.G.
- Yu C.E.
- Yu L.
- Zare H.
- Zhang X.
- Zhang Y.
- Zhao Y.
- Zhao Y.
- Zhou W.
- Zhu C.
- Zhu X.
- Ziemann A.
- Zoia C.P.
- Zompo M.D.
- Zulaica M.
- Ălvarez V.
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE Δ4 allele
Treating Denim Fabrics with Trichoderma Reesei Cellulases
- Author
- Publication venue
- 'SAGE Publications'
- Publication date
- 01/01/2000
- Field of study
Size distribution analysis for copper matte particles oxidized under flash-converting conditions
- Author
- A. Asteljoki
- A. Jokilaakso
- A.A. Shook
- D. Swartling
- D.B. George
- D.M. Jones
- E.G. Kelly
- F.R. Jorgensen
- G.J. Morgan
- H. Kim
- Hong Yong Sohn
- I. Deltapoint
- J.G. Dunn
- José A. Tirado-Ochoa
- K.M. Riihilahti
- M. Perez-Tello
- M. PĂ©rez-Tello
- Manuel PĂ©rez-Tello
- R.L. Scheaffer
- R.O. Suominen
- R.O. Suominen
- S. Strömberg
- S. Strömberg
- VĂctor M. SĂĄnchez-Corrales
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Development of a core outcome set for congenital pulmonary airway malformations: study protocol of an international Delphi survey
- Author
- A. Bonnard
- A. Lain
- A. SgrĂČ
- Alberto Sgro
- C. Bitkover
- C. K. van der Ent
- C. Mesas Burgos
- C. Wallis
- C.M. Kersten
- Carmen Mesas Burgos
- Casper Kersten
- D. Cox
- D. Mullassery
- D. Vervloessem
- Dhanya Mullassery
- E. Caffrey Osvald
- E. Haarman
- E. Hannon
- F. Morini
- G. Aksnes
- G. Gollu
- G. Singer
- H. Decaluwé
- H. Schaballie
- H. Steyaert
- H. Till
- H.A.W.M. Tiddens
- Harm A W M Tiddens
- Holger Till
- I. Sinha
- I. Yardley
- J. Deprest
- J. Roukema
- J. Suominen
- J.M. Schnater
- Janne Suominen
- K. Zahn
- K.M. Winter-de Groot
- Kjetil Ertresvag
- L. Desender
- L. Martelius
- L. Wessel
- Liesbeth Desender
- M. Bannier
- M. Boon
- M. Metzelder
- M. Pakarinen
- M. Proesmans
- M. Schurink
- M. Singh
- M. Stanton
- M. Zampoli
- Maarten Schurink
- Marco Schnater
- N. Cobanoglu
- N. Muthialu
- N. Qvist
- N. Rikkers-Mutsaerts
- Nagarajan Muthialu
- Nazan Cobanoglu
- P Sezen
- P. Bagolan
- P. Conner
- P. Gamba
- P.D. Losty
- Paul Losty
- Pietro Bagolan
- Q. Jöbsis
- R. Peters
- R. Sfeir
- R.M.H. Wijnen
- René M H Wijnen
- S. de Beer
- S. Gartner
- S. Heyman
- S. Terheggen-Lagro
- S. van der Heide
- S.C.M. Cochius
- S.M. Hermelijn
- Sergei Hermelijn
- Silvia Gartner
- Stijn Heyman
- T. Schaible
- Publication venue
- 'BMJ'
- Publication date
- 01/04/2021
- Field of study
Introduction A worldwide lack of consensus exists on the optimal management of asymptomatic congenital pulmonary airway malformation (CPAM) even though the incidence is increasing. Either a surgical resection is performed or a wait-and-see policy is employed, depending on the treating physician. Management is largely based on expert opinion and scientific evidence is scarce. Wide variations in outcome measures are seen between studies making comparison difficult thus highlighting the lack of universal consensus in outcome measures as well. We aim to define a core outcome set which will include the most important core outcome parameters for paediatric patients with an asymptomatic CPAM.Methods and analysis This study will include a critical appraisal of the current literature followed by a three-stage Delphi process with two stakeholder groups. One surgical group including paediatric as well as thoracic surgeons, and a non-surgeon group including paediatric pulmonologists, intensive care and neonatal specialists. All participants will score outcome parameters according to their level of importance and the most important parameters will be determined by consensus.Ethics and dissemination Electronic informed consent will be obtained from all participants. Ethical approval is not required. After the core outcome set has been defined, we intend to design an international randomised controlled trial: the COllaborative Neonatal NEtwork for the first CPAM Trial, which will be aimed at determining the optimal management of patients with asymptomatic CPAM
Management of primary breast cancer.
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- A Liberati
- A Melville
- Alliance National Cancer
- Amir M.
- Arathuzik D.
- Azzarelli A.
- Baildam A.D.
- Basnett I.
- Berglund G.
- Bindemann S.
- Blanchard C.G.
- Bloom J.
- Boffetta P.
- Bridge L.R.
- Brown L.A.
- Bulbrook R.D.
- Bullough B.
- Burish T.G.
- Burish T.G.
- Burish T.G.
- Burish T.G.
- Burton M.V.
- Butler J.A.
- Byrne M.J.
- Cannici J.
- Cassileth B.R.
- Chaitchik S.
- Ciatto S.
- Cimprich B.
- Cipolla C.
- Committee Mahrer
- Cooper G.G.
- Corry J.F.
- Cotanch P.E.
- Cotton T.
- Dalton J.A.
- Davis H.
- Degner L.F.
- Deustch G.
- Dixon J.M.
- Dodd M.J.
- Eardley A.
- Edgar L.
- Epstein R.
- F Norcross Weinstreub
- F Norcross Weinstreub
- Fallowfield U.
- Faulkner A.
- Fawzy F.I.
- Ferguson C.M.
- Filiberti A.
- Fisher B.
- for Cancer Care Evaluation GIVIO (Interdisciplinary Group
- Ford S.
- Foster R.S.
- Funch D.P.
- Galea M.
- Gillis C.R.
- Goldberg P.
- Gordon W.A.
- Green B.
- Greenwald H.P.
- Greer S.
- Griffiths M.
- Grilli R.
- Grossarth M.R.
- Gruber B.L.
- Hack T.F.
- Hand R.
- Hansen J.L.
- Hill D.J.
- Hogbin B.
- Holland J.C.
- Houts P.S.
- Hughes K.K.
- Hynes D.M.
- Kocjan G.
- Koss L.G.
- Kreuzer G.
- Larsson G.
- Layfield U.
- Lee-Feldstein A.
- Leinster S.J.
- Lerman C.
- Levy S.M.
- Lyles J.N.
- Macmillan R.D.
- Maguire P.
- Maguire P.
- Maguire P.
- Maguire P.
- Maguire P.
- Mapelli V.
- Martelli G.
- Maunsell E.
- Mayer T.J.
- McArdle J.M.C.
- McCarthy M.
- McHugh P.
- McLean M.
- Miransky J.
- Mock V.
- Mock V.
- Moorey S.
- Morgenstern H.
- Morris J.
- Morrow G.R.
- Morrow G.R.
- Nattinger A.B.
- Neufeld K.R.
- Neuling S.J.
- Northouse L.L.
- O'Gormon E.C.
- of Populations Office
- Palombini L.
- Pierce P.F.
- Porter H.B.
- Porter H.B.
- Pozo C.
- Pozo C.
- R Grilli
- Rainey L.C.
- Ramirez A.J.
- Ray C.
- Recht A.
- Richards M.A.
- Roberts C.S.
- Roberts R.
- S Di Pietro
- S Di Pietro
- Sainsbury R.
- Sainsbury R.
- Satariano E.R.
- Schain W.S.
- Schmidt W.A.
- Schover L.R.
- Scorpiglione N.
- Silberfarb P.M.
- Siminoff L.A.
- Sloan F.A.
- Smith T.J.
- Spiegel D.
- Spiegel D.
- Spiegel D.
- Stevens L.A.
- Stiller C.A.
- Street R.L.
- Studnicki J.
- Suominen T.
- Suominen T.
- Suominen T.
- Suominen T.
- Suominen T.
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- T Sheldon
- Tait A.
- Taylor K.M.
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- Thomas M.J.
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- Vickers A.J.
- Ward S.
- Watson M.
- Waxler-Morrison N.
- Whelan J.
- Wilkinson S.
- Wilson R.G.
- Winstanley J.H.R.
- Wolberg W.H.
- Youssef F.A.
- Youssef F.A.
- Zemore R.
- Publication venue
- 'BMJ'
- Publication date
- Field of study
Effects of scale on interpreting life-history characteristics of ungulates and carnivores
- Author
- Albert D.M.
- Allen T.F.H.
- Andersen R.
- Anderson R.C.
- Ballard W.B.
- Barboza P.S.
- Barten N.L.
- Ben-David M.
- Bleich V.C.
- Bleich V.C.
- Bowyer R.T.
- Bowyer R.T.
- Bowyer R.T.
- Bowyer R.T.
- Bowyer R.T.
- Bowyer R.T.
- Bowyer R.T.
- Bowyer R.T.
- Bowyer R.T.
- Bowyer R.T.
- Boyce M.S.
- Bryant J.P.
- Carr M.M.
- de Calesta D.S.
- Dutilleul P.
- Etchberger R.C.
- Frank D.A.
- Gardner R.H.
- Gasaway W.G.
- Goodwin B.J.
- Greenberg J.D.
- Hayes R.D.
- Hodgman T.P.
- Irons J.G.
- Johnson C.J.
- Johnson D.H.
- Kie J.G.
- Kie J.G.
- Kie J.G.
- Kie J.G.
- King A.W.
- Leslie D.M.
- Levin S.A.
- Massei G.
- McCullough D.R.
- McCullough D.R.
- McCullough D.R.
- McShea W.J.
- Nicholson M.C.
- Nielsen D.G.
- O'Neill R.V.
- O'Neill R.V.
- Oehler M.W. Sr
- Packer P.E.
- Packer P.E.
- Parker K.L.
- Person D.K.
- Pierce B.M.
- Pierce B.M.
- Powell R.A.
- Schneider D.C.
- Spaeth D.F.
- Stewart K.M.
- Suominen O.
- Telfer E.S.
- Telfer E.S.
- Telfer E.S.
- Turner M.G.
- Ward D.
- Publication venue
- 'Wiley'
- Publication date
- Field of study
The genetic and ecophysiological diversity of Microcystis
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- Agha R.
- Agrawal A.A.
- Agrawal A.A.
- Ahlgren G.
- Akins L.
- Alexova R.
- Alexova R.
- Amin S.A.
- Amé M.V.
- Anderson C.R.
- ArandiaâGorostidi N.
- Arevalo P.
- Aulnoies M.G.
- Baker J.A.
- Baldia S.F.
- Bapteste E.
- Barchewitz T.
- Bastviken D.T.E.
- Batista A.M.M.
- Bayer B.
- BañaresâEspaña E.
- Beardall J.
- Berry M.A.
- Beversdorf L.J.
- Biller S.J.
- Bittencourtâoliveira M.C.
- Bobay L.M.
- BouaĂŻcha N.
- Bouchard J.N.
- Bozarth C.S.
- Brandenburg K.M.
- Bratbak G.
- Breitbart M.
- Briand E.
- Briand E.
- Briand E.
- Briand E.
- Brookes J.D.
- Brookes J.D.
- Brum J.R.
- Brunberg A.K.
- Bui T.
- Burberg C.
- Burns C.W.
- Cai H.
- Caiola M.G.
- Carmichael W.W.
- Carmichael W.W.
- Cataldo D.
- Chaffin J.D.
- Chan J.Z.M.
- Chase J.M.
- Chernoff N.
- Chia M.A.
- Chislock M.F.
- Chorus I.
- ChristieâOleza J.A.
- Chu Z.
- Chun S.J.
- Cook K.V.
- Cooper W.J.
- Cory R.M.
- Cosgrove K.
- Costas E.
- Cottingham K.L.
- Croft M.T.
- Davis T.W.
- Davis T.W.
- Davis T.W.
- Deblois C.P.
- Denef V.J.
- Dick G.J.
- Dittmann E.
- Donald D.B.
- Dong J.
- Downing T.G.
- Droop M.
- DrĂĄbkovĂĄ M.
- Duan Z.
- Durham B.P.
- Durham B.P.
- Dziallas C.
- DĂaz S.
- Ehrenreich I.M.
- Errera R.M.
- Flynn K.J.
- Fogg G.E.
- Follows M.J.
- Fontana S.
- Forni C.
- Frenken T.
- Fuhrman J.A.
- Gao K.
- Ger K.A.
- Ger K.A.
- Ger K.A.
- Gerloff G.
- Gerphagnon M.
- Giordano M.
- Gleason F.H.
- Glibert P.M.
- Glibert P.M.
- Gobler C.J.
- Grossart H.P.
- Gu B.
- Guan D.X.
- Harke M.J.
- Harke M.J.
- Harke M.J.
- Harke M.J.
- Harvey B.P.
- Healey F.P.
- Hellweger F.L.
- Hennon G.M.
- Hesse K.
- Hillebrand H.
- Ho J.C.
- Holm N.P.
- Honjo M.
- Horst G.P.
- Hughes A.R.
- Huisman J.
- Huisman J.
- Huisman J.
- Humbert J.F.
- Humbert J.F.
- Jackrel S.L.
- Jackrel S.L.
- Jackrel S.L.
- Jacquet S.
- Jahnichen S.
- Jankowiak J.
- Jankowiak J.G.
- Janse I.
- Joung S.H.
- Jover L.F.
- Juhel G.
- Jungmann D.
- Kaebernick M.
- Kane D.D.
- Kappers F.
- Kardinaal W.E.A.
- Kehr J.C.
- Kim J.G.
- Kim M.
- Kimura S.
- Kitchens C.M.
- KomĂĄrek J.
- Kondo R.
- Konstantinidis K.T.
- Kramer B.J.
- Krause S.
- Krausfeldt L.E.
- Kurmayer R.
- Legrand C.
- Lehman P.W.
- Lei L.
- Leibold M.A.
- Leibold M.A.
- Lemaire V.
- Lezcano M.
- Li A.
- Li P.
- Lima S.L.
- Litchman E.
- Liu J.
- Lyck S.
- Lynch M.
- Lyu K.
- LĂłpezâRodas V.
- LĂŒrling M.
- LĂŒrling M.
- Ma L.
- Makower A.K.
- Manage P.M.
- Manage P.M.
- MankiewiczâBoczek J.
- Marinho M.M.
- Martiny J.B.H.
- Matthijs H.C.P.
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- Meyer K.A.
- Michalak A.M.
- Mikalsen B.
- Mikula P.
- Miller M.A.
- Mohamed Z.A.
- Moisander P.H.
- Monchamp M.E.
- Morimoto D.
- Morris J.J.
- Morris J.J.
- Morris J.J.
- Morris J.J.
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- Muraille E.
- Nemergut D.R.
- Nolan M.P.
- O'Neil J.M.
- Ohtake A.
- Olsen Y.
- Olsen Y.
- Omata T.
- Omidi A.
- Orr P.T.
- Ostrowski M.
- Otsuka S.
- Otsuka S.
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- Publication venue
- 'Wiley'
- Publication date
- 01/12/2021
- Field of study
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/171576/1/emi15615.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/171576/2/emi15615-sup-0002-FigureS1.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/171576/3/emi15615_am.pd
New insights into the genetic etiology of Alzheimerâs disease and related dementias
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
Characterization of the genetic landscape of Alzheimerâs disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/âproxyâ AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE Δ4 allele. © 2022, The Author(s)