533 research outputs found
Classical integrability and quantum aspects of the AdS(3) x S(3) x S(3) x S(1) superstring
In this paper we continue the investigation of aspects of integrability of
the type IIA AdS(3) x S(3) x S(3) x S(1) and AdS(3) x S(3) x T(4) superstrings.
By constructing a one parameter family of flat connections we prove that the
Green-Schwarz string is classically integrable, at least to quadratic order in
fermions, without fixing the kappa-symmetry. We then compare the quantum
dispersion relation, fixed by integrability up to an unknown interpolating
function h(lambda), to explicit one-loop calculations on the string worldsheet.
For AdS(3) x S(3) x S(3) x S(1) the spectrum contains heavy, as well as light
and massless modes, and we find that the one-loop contribution differs
depending on how we treat these modes showing that similar regularization
ambiguities as appeared in AdS(4)/CFT(3) occur also here.Comment: 29 pages; v2: updated references and acknowledgmen
Lack of effect of treating Helicobacter pylori infection in patients with nonulcer dyspepsia. Omeprazole plus Clarithromycin and Amoxicillin Effect One Year after Treatment (OCAY) Study Group.
It is uncertain whether treatment of Helicobacter pylori infection relieves symptoms in patients with nonulcer, or functional, dyspepsia. METHODS: We conducted a double-blind, multicenter trial of patients with H. pylori infection and dyspeptic symptoms (moderate-to-very-severe pain and discomfort centered in the upper abdomen). Patients were excluded if they had a history of peptic ulcer disease or gastroesophageal reflux disease and had abnormal findings on upper endoscopy. Patients were randomly assigned to seven days of treatment with 20 mg of omeprazole twice daily, 1000 mg of amoxicillin twice daily, and 500 mg of clarithromycin twice daily or with omeprazole alone and then followed up for one year. Treatment success was defined as the absence of dyspeptic symptoms or the presence of minimal symptoms on any of the 7 days preceding the 12-month visit. RESULTS: Twenty of the 348 patients were excluded after randomization because they were not infected with H. pylori, were not treated, or had no data available. For the remaining 328 patients (164 in each group), treatment was successful for 27.4 percent of those assigned to receive omeprazole and antibiotics and 20.7 percent of those assigned to receive omeprazole alone (P=0.17; absolute difference between groups, 6.7 percent; 95 percent confidence interval, -2.6 to 16.0). After 12 months, gastritis had healed in 75.0 percent of the patients in the group given omeprazole and antibiotics and in 3.0 percent of the patients in the omeprazole group (P<0.001); the respective rates of H. pylori eradication were 79 percent and 2 percent. In the group given omeprazole and antibiotics, the rate of treatment success among patients with persistent H. pylori infection was similar to that among patients in whom the infection was eradicated (26 percent vs. 31 percent). There were no significant differences between the groups in the quality of life after treatment. CONCLUSIONS: In patients with nonulcer dyspepsia, the eradication of H. pylori infection is not likely to relieve symptoms
Review of AdS/CFT Integrability, Chapter IV.3: N=6 Chern-Simons and Strings on AdS4xCP3
We review the duality and integrability of N=6 superconformal Chern-Simons
theory in three dimensions and IIA superstring theory on the background
AdS4xCP3. We introduce both of these models and describe how their degrees of
freedom are mapped to excitations of a long-range integrable spin-chain.
Finally, we discuss the properties of the Bethe equations, the S-matrix and the
algebraic curve that are special to this correspondence and differ from the
case of N=4 SYM theory and strings on AdS5xS5.Comment: 22 pages, see also overview article arXiv:1012.3982, v2: references
to other chapters updated, v3: references added, v4: brief discussion of
giant magnons added, further minor changes, published version, v5: union of
v3 and v4 because changes made in v3 were accidentally lost in v
Integrating isotopes and documentary evidence : dietary patterns in a late medieval and early modern mining community, Sweden
We would like to thank the Archaeological Research Laboratory, Stockholm University, Sweden and the Tandem Laboratory (Ă
ngström Laboratory), Uppsala University, Sweden, for undertaking the analyses of stable nitrogen and carbon isotopes in both human and animal collagen samples. Also, thanks to Elin Ahlin Sundman for providing the ÎŽ13C and ÎŽ15N values for animal references from VĂ€sterĂ„s. This research (BĂ€ckströmâs PhD employment at Lund University, Sweden) was supported by the Berit Wallenberg Foundation (BWS 2010.0176) and Jakob and Johan Söderbergâs foundation. The âSala projectâ (excavations and analyses) has been funded by Riksens Clenodium, Jernkontoret, Birgit and Gad Rausingâs Foundation, SAUâs Research Foundation, the Royal Physiographic Society of Lund, Berit Wallenbergs Foundation, Ă
ke Wibergs Foundation, Lars Hiertas Memory, Helge Ax:son Johnsonâs Foundation and The Royal Swedish Academy of Sciences.Peer reviewedPublisher PD
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The influence of the accessory genome on bacterial pathogen evolution
Bacterial pathogens exhibit significant variation in their genomic content of virulence factors. This reflects the abundance of strategies pathogens evolved to infect host organisms by suppressing host immunity. Molecular arms-races have been a strong driving force for the evolution of pathogenicity, with pathogens often encoding overlapping or redundant functions, such as type III protein secretion effectors and hosts encoding ever more sophisticated immune systems. The pathogensâ frequent exposure to other microbes, either in their host or in the environment, provides opportunities for the acquisition or interchange of mobile genetic elements. These DNA elements accessorise the core genome and can play major roles in shaping genome structure and altering the complement of virulence factors. Here, we review the different mobile genetic elements focusing on the more recent discoveries and highlighting their role in shaping bacterial pathogen evolution
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