94 research outputs found

    The Cognitive Load of Observation Tasks in 3D Video is Lower Than That in 2D Video

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    We are exposed to more and more 3D videos, some for entertainment and some for scientific research. Some experiments using 3D video as a stimulus focus only on its visual effect. We studied the cognitive difference between 3D and 2D videos by analyzing EEG. This research adopts a 2 x 4 experimental design, including 2D and 3D versions of 4 video scenes. These four video scenes can be classified into two simple task scenes and two complex task scenes. The simple task scenario and the complex task scenario each contain a video with violent content changes and a calm video. Subjects need to watch eight videos. We recorded the EEG information of the subjects and analyzed the power of alpha and theta oscillations. On this basis, we calculated the cognitive load index (CLI), which can be used as an indicator of cognitive load. The results showed that 3D videos that required subjects to perform simple tasks brought higher cognitive load to most subjects. When the video contains complex tasks, the cognitive load of subjects does not show similar regularity. Specifically, only half of the people had higher cognitive load when watching the 3D version of the video than when watching the 2D version. In addition, the cognitive load level of subjects showed significant individual differencesComment: 7 pages, 18 figure

    Multisystem optimization for an integrated production scheduling with resource saving problem in textile printing and dyeing

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    Resource saving has become an integral aspect of manufacturing in industry 4.0. This paper proposes a multisystem optimization (MSO) algorithm, inspired by implicit parallelism of heuristic methods, to solve an integrated production scheduling with resource saving problem in textile printing and dyeing. First, a real-world integrated production scheduling with resource saving is formulated as a multisystem optimization problem. Then, the MSO algorithm is proposed to solve multisystem optimization problems that consist of several coupled subsystems, and each of the subsystems may contain multiple objectives and multiple constraints. The proposed MSO algorithm is composed of within-subsystem evolution and cross-subsystem migration operators, and the former is to optimize each subsystem by excellent evolution operators and the later is to complete information sharing between multiple subsystems, to accelerate the global optimization of the whole system. Performance is tested on a set of multisystem benchmark functions and compared with improved NSGA-II and multiobjective multifactorial evolutionary algorithm (MO-MFEA). Simulation results show that the MSO algorithm is better than compared algorithms for the benchmark functions studied in this paper. Finally, the MSO algorithm is successfully applied to the proposed integrated production scheduling with resource saving problem, and the results show that MSO is a promising algorithm for the studied problem. © 2020 Haiping Ma et al

    New insights into the BiB 3 O 6 melt structure3

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    The structure of borate melt has long been a fundamental unsolved problem in condensed matter physics, materials chemistry. Here, we use high temperature Raman spectroscopy and first principles calculations to study the structural change before and after the melting of a BiB 3 O 6 crystal to obtain the BiB 3 O 6 melt structure. A transformation of the 4-fold coordinated boron atoms to 3-fold coordinated boron atoms and a destruction of the atomic configuration around the Bi 3+ ions were found when the crystal melted. Considering the growth habit of the BIBO crystal, we proposed a polymer model for the first time to describe the melt structure

    Weighted gene co-expression network analysis identifies genes related to HG Type 0 resistance and verification of hub gene GmHg1

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    IntroductionThe soybean cyst nematode (SCN) is a major disease in soybean production thatseriously affects soybean yield. At present, there are no studies on weighted geneco-expression network analysis (WGCNA) related to SCN resistance.MethodsHere, transcriptome data from 36 soybean roots under SCN HG Type 0 (race 3) stresswere used in WGCNA to identify significant modules.Results and DiscussionA total of 10,000 differentially expressed genes and 21 modules were identified, of which the module most related to SCN was turquoise. In addition, the hub gene GmHg1 with high connectivity was selected, and its function was verified. GmHg1 encodes serine/threonine protein kinase (PK), and the expression of GmHg1 in SCN-resistant cultivars (‘Dongnong L-204’) and SCN-susceptible cultivars (‘Heinong 37’) increased significantly after HG Type 0 stress. Soybean plants transformed with GmHg1-OX had significantly increased SCN resistance. In contrast, the GmHg1-RNAi transgenic soybean plants significantly reduced SCN resistance. In transgenic materials, the expression patterns of 11 genes with the same expression trend as the GmHg1 gene in the ‘turquoise module’ were analyzed. Analysis showed that 11genes were co-expressed with GmHg1, which may be involved in the process of soybean resistance to SCN. Our work provides a new direction for studying the Molecular mechanism of soybean resistance to SCN

    Population pharmacokinetics of nalbuphine in patients undergoing general anesthesia surgery

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    Purpose: The aim of this study was to build a population pharmacokinetics (PopPK) model of nalbuphine and to estimate the suitability of bodyweight or fixed dosage regimen.Method: Adult patients who were undergoing general anesthetic surgery using nalbuphine for induction of anesthesia were included. Plasma concentrations and covariates information were analyzed by non-linear mixed-effects modeling approach. Goodness-of-fit (GOF), non-parametric bootstrap, visual predictive check (VPC) and external evaluation were applied for the final PopPK model evaluation. Monte Carlo simulation was conducted to assess impact of covariates and dosage regimens on the plasma concentration to nalbuphine.Results: 47 patients aged 21–78 years with a body weight of 48–86 kg were included in the study. Among them, liver resection accounted for 14.8%, cholecystectomy for 12.8%, pancreatic resection for 36.2% and other surgeries for 36.2%. 353 samples from 27 patients were enrolled in model building group; 100 samples from 20 patients were enrolled in external validation group. The results of model evaluation showed that the pharmacokinetics of nalbuphine was adequately described by a two-compartment model. The hourly net fluid volume infused (HNF) was identified as a significant covariate about the intercompartmental clearance (Q) of nalbuphine with objective function value (OFV) decreasing by 9.643 (p < 0.005, df = 1). Simulation results demonstrated no need to adjust dosage based on HNF, and the biases of two dosage methods were less than 6%. The fixed dosage regimen had lower PK variability than the bodyweight regimen.Conclusion: A two-compartment PopPK model adequately described the concentration profile of nalbuphine intravenous injection for anesthesia induction. While HNF can affect the Q of nalbuphine, the magnitude of the effect was limited. Dosage adjustment based on HNF was not recommended. Furthermore, fixed dosage regimen might be better than body weight dosage regimen

    Identification of renal cyst cells of type I Nephronophthisis by single-nucleus RNA sequencing

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    Background: Nephronophthisis (NPH) is the most common genetic cause of end-stage renal disease (ESRD) in childhood, and NPHP1 is the major pathogenic gene. Cyst formation at the corticomedullary junction is a pathological feature of NPH, but the mechanism underlying cystogenesis is not well understood. The isolation and identification of cystic cell subpopulation could help to identify their origins and provide vital clues to the mechanisms underlying cystogenesis in NPH.Methods: Single-nucleus RNA sequencing (snRNA-seq) was performed to produce an atlas of NPHP1 renal cells. Kidney samples were collected from WT (Nphp1+/+) mice and NPHP1 (Nphp1del2-20/del2-20) model mice.Results: A comprehensive atlas of the renal cellular landscape in NPHP1 was generated, consisting of 14 basic renal cell types as well as a subpopulation of DCT cells that was overrepresented in NPHP1 kidneys compared to WT kidneys. GO analysis revealed significant downregulation of genes associated with tubular development and kidney morphogenesis in this subpopulation. Furthermore, the reconstruction of differentiation trajectories of individual cells within this subpopulation confirmed that a specific group of cells in NPHP1 mice become arrested at an early stage of differentiation and proliferate to form cysts. We demonstrate that Niban1 is a specific molecular marker of cystic cells in both mice and human NPHP1.Conclusion: In summary, we report a novel subpopulation of DCT cells, marked by Niban1, that are classified as cystic cells in the NPHP1 mice kidney. These results offer fresh insights into the cellular and molecular basis of cystogenesis in NPH

    Research on bandwidth reservation in IEEE 802.16 (WiMAX) networks

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    According to the characteristics and QoS requirements of different types of service flows, this paper proposes a dynamic, prediction-based, multi-class, adaptive bandwidth reservation scheme for IEEE 802.16 (WiMAX) networks. The scheme adopts different bandwidth reservation and admission control policies to different types of service flows and therefore guarantees that the real-time sessions have higher priorities than non real-time sessions and that handover sessions have higher priorities than new sessions. In addition, a bandwidth reservation adaptation algorithm is also proposed. The algorithm adjusts the amount of bandwidth reserved for handover sessions according to the current network conditions thus creating a balance between new session blocking rate and handover session dropping rate

    Generic scheduling framework and algorithm for time-varying wireless networks

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    In this paper, the problem of scheduling multiple users sharing a time varying wireless channel is studied, in networks such as in 3G CDMA and IEEE 802.16. We propose a new generic wireless packet scheduling framework (WPSF), which takes into account not only the quality of service (QoS) requirements but also the wireless resource consumed. The framework is generic in the sense that it can be used with different resource constraints and QoS requirements depending on the traffic flow types. Subsequently, based on this framework a minimum rate and channel aware (MRCA) scheduling algorithm is presented. MRCA attempts to greedily enhance wireless channel efficiency by making use of multi-user channel quality diversity, while providing acceptable QoS in term of users\u27 minimum rate constraints. Simulation results show the desirable properties identified in the algorithm
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