The Tensor Current Divergence Equation in U(1) Gauge Theories is Free of Anomalies

The possible anomaly of the tensor current divergence equation in U(1) gauge theories is calculated by means of perturbative method. It is found that the tensor current divergence equation is free of anomalies.Comment: Revtex4, 7 pages, 2 figure

Security of a new two-way continuous-variable quantum key distribution protocol

The original two-way continuous-variable quantum-key-distribution (CV QKD) protocols [S. Pirandola, S. Mancini, S. Lloyd, and S. L. Braunstein, Nature Physics 4, 726 (2008)] give the security against the collective attack on the condition of the tomography of the quantum channels. We propose a family of new two-way CV QKD protocols and prove their security against collective entangling cloner attacks without the tomography of the quantum channels. The simulation result indicates that the new protocols maintain the same advantage as the original two-way protocols whose tolerable excess noise surpasses that of the one-way CV-QKD protocol. We also show that all sub-protocols within the family have higher secret key rate and much longer transmission distance than the one-way CV-QKD protocol for the noisy channel.Comment: 19 pages, 4 figures, accepted for publication in International Journal of Quantum Informatio

Improvement of two-way continuous-variable quantum key distribution using optical amplifiers

The imperfections of a receiver's detector affect the performance of two-way continuous-variable quantum key distribution protocols and are difficult to adjust in practical situations. We propose a method to improve the performance of two-way continuous-variable quantum key distribution by adding a parameter-adjustable optical amplifier at the receiver. A security analysis is derived against a two-mode collective entangling cloner attack. Our simulations show that the proposed method can improve the performance of protocols as long as the inherent noise of the amplifier is lower than a critical value, defined as the tolerable amplifier noise. Furthermore, the optimal performance can approach the scenario where a perfect detector is used.Comment: 14 pages, 7 figure

Neobaicalein prevents isoflurane anesthesia-induced cognitive impairment in neonatal mice via regulating CREB1

Objectives: Isoflurane (ISO) is widely used in the clinic and research. The authors aimed to explore whether Neobaicalein (Neob) could protect neonatal mice from ISO-induced cognitive damage. Method: The open field test, Morris water maze test, and tail suspension test was performed to assess the cognitive function in mice. Enzyme-linked immunosorbent assay was used to evaluate inflammatory-related protein concentrations. Immunohistochemistry was used to assess Ionized calcium-Binding Adapter molecule-1 (IBA-1) expression. Hippocampal neuron viability was detected using the Cell Counting Kit-8 assay. Double immunofluorescence staining was employed to confirm the interaction between proteins. Western blotting was used to assess protein expression levels. Results: Neob notably improved cognitive function and exhibited anti-inflammatory effects; moreover, under iso-treatment, it exhibited neuroprotective effects. Furthermore, Neob suppressed interleukin-1β, tumor necrosis factor-α, and interleukin-6 levels and upregulated interleukin-10 levels in ISO-treated mice. Neob significantly mitigated iso-induced increases in IBA-1–positive cell numbers of the hippocampus in neonatal mice. Furthermore, it inhibited ISO-induced neuronal apoptosis. Mechanistically, Neob was observed to upregulate cAMP Response Element Binding protein (CREB1) phosphorylation and protected hippocampal neurons from ISO-mediated apoptosis. Moreover, it rescued ISO-induced abnormalities of synaptic protein. Conclusions: Neob prevented ISO anesthesia-induced cognitive impairment by suppressing apoptosis and inflammation through upregulating CREB1

Study on Complex Products Job-shop Scheduling System Based on MES

Various random disturbances that happen in the process of complex products (ship) production cannot feedback timely, and the plans of job-shop operation are too rough to instruct job-shop production. The purpose of this study is to solve the problems above, help the course of complex products (ship) job-shop production runs orderly and efficiently, and improve the job-shop on-site management level. In this paper, we proposed complex products job-shop scheduling system based on MES. The system adopts six-level, refined plan and scheduling mechanism. Its key part is the job-shop scheduling model with man-machine coordinated mechanism. What’s more, an improved Genetic Algorithm based on TOC is proposed to make the optimized algorithm module of the system more scientific and effective. Key words: Complex Products; MES; Job-shop Scheduling System; Man-machine Coordinated Mechanism; Genetic Algorithm Résumé: Diverses perturbations qui se produisent au hasard dans le processus de production des produits complexes (navire) ne peuvent pas être apperçues en temps opportun, et les plans de l'opération des ateliers sont trop approximatifs pour guider la production. Le but de cette étude consiste à résoudre les problèmes ci-dessus, rendre le cours de la production des produits complexes (ship) dans les ateliers ordonné et efficace et améliorer le niveau de gestion sur place. Dans cet article, nous avons proposé le système de planning des ateliers de produits complexes basé sur MES. Le système contient six niveaux de programmation raffinée et de mécanismes de planning. Son élément essentiel est le modèle de programmation avec les mécanismes de coordination homme-machine. De plus, un algorithme génétique amélioré basé sur TOC est également proposé de rendre le module de l'algorithme du système optimisé plus scientifique et efficace. Mots-clés: produits complexes; MES; système de planning des ateliers; mécanismes de coordination homme-machine; algorithme génétique 摘要：針對目前複雜產品（船舶）生產過程中所出現的各種隨機擾動不能得到及時回饋，以及車間作業計畫粗略難以直接指導車間生產的現狀，本文提出基於 MES的複雜產品車間作業調度系統。該系統採用逐層細化的五級計畫與調度機制，以人機協同的車間作業調度模型為核心，通過改進基於 TOC的遺傳演算法，使系統的演算法模組優化性能更具有科學性和操作性。該系統有助於實現複雜產品（船舶）車間生產過程的有序運作，從而提高生產車間的現場管理水準。 關鍵字：複雜產品； MES；車間作業調度；人機協同；遺傳演算

A Note on Optimality Conditions for DC Programs Involving Composite Functions

By using the formula of the ε-subdifferential for the sum of a convex function with a composition of convex functions, some necessary and sufficient optimality conditions for a DC programming problem involving a composite function are obtained. As applications, a composed convex optimization problem, a DC optimization problem, and a convex optimization problem with a linear operator are examined at the end of this paper

A prediction model for N2 disease in T1 non–small cell lung cancer

ObjectiveControversy remains over the routine use of mediastinoscopy or positron emission tomography in T1 non–small cell lung cancer without lymph node enlargement on computed tomography because the risk of N2 involvement is comparatively low. We aimed to develop a prediction model for N2 disease in cT1N0 non–small cell lung cancer to aid in the decision-making process.MethodsWe reviewed the records of 530 patients with computed tomography–defined T1N0 non–small cell lung cancer who underwent surgical resection with systematic lymph node dissection. Correlations between N2 involvement and clinicopathologic parameters were assessed using univariate analysis and binary logistic regression analysis. A prediction model was built on the basis of logistic regression analysis and was internally validated using bootstrapping.ResultsThe incidence of N2 disease was 16.8%. Four independent predictors were identified in multivariate logistic regression analysis and included in the prediction model: younger age at diagnosis (odds ratio, 0.974; 95% confidence interval, 0.952-0.997), larger tumor size (odds ratio, 2.769; 95% confidence interval, 1.818-4.217), central tumor location (odds ratio, 3.204; 95% confidence interval, 1.512-6.790), and invasive adenocarcinoma histology (odds ratio, 3.537; 95% confidence interval, 1.740-7.191). This model shows good calibration (Hosmer–Lemeshow test: P = .784), reasonable discrimination (area under the receiver operating characteristic curve, 0.726; 95% confidence interval, 0.669-0.784), and minimal overfitting demonstrated by bootstrapping.ConclusionsWe developed a 4-predictor model that can estimate the probability of N2 disease in computed tomography–defined T1N0 non–small cell lung cancer. This prediction model can help to determine the cost-effective use of mediastinal staging procedures

Topological triply-degenerate point with double Fermi arcs

Unconventional chiral particles have recently been predicted to appear in certain three dimensional (3D) crystal structures containing three- or more-fold linear band degeneracy points (BDPs). These BDPs carry topological charges, but are distinct from the standard twofold Weyl points or fourfold Dirac points, and cannot be described in terms of an emergent relativistic field theory. Here, we report on the experimental observation of a topological threefold BDP in a 3D phononic crystal. Using direct acoustic field mapping, we demonstrate the existence of the threefold BDP in the bulk bandstructure, as well as doubled Fermi arcs of surface states consistent with a topological charge of 2. Another novel BDP, similar to a Dirac point but carrying nonzero topological charge, is connected to the threefold BDP via the doubled Fermi arcs. These findings pave the way to using these unconventional particles for exploring new emergent physical phenomena