How the presentation of patient information and decision-support advisories influences opioid prescribing behavior: A simulation study

ObjectiveThe United States faces an opioid crisis. Integrating prescription drug monitoring programs into electronic health records offers promise to improve opioid prescribing practices. This study aimed to evaluate 2 different user interface designs for prescription drug monitoring program and electronic health record integration.Materials and MethodsTwenty-four resident physicians participated in a randomized controlled experiment using 4 simulated patient cases. In the conventional condition, prescription opioid histories were presented in tabular format, and computerized clinical decision support (CDS) was provided via interruptive modal dialogs (ie, pop-ups). The alternative condition featured a graphical opioid history, a cue to visit that history, and noninterruptive CDS. Two attending pain specialists judged prescription appropriateness.ResultsParticipants in the alternative condition wrote more appropriate prescriptions. When asked after the experiment, most participants stated that they preferred the alternative design to the conventional design.ConclusionsHow patient information and CDS are presented appears to have a significant influence on opioid prescribing behavior

A New Modified MPPT Controller for Indirect Vector Controlled Induction Motor Drive with Variable Irradiance and Variable Temperature

Due to the increase in power demand and the earth natural resources are depleting day by day, renewable energy sources have become an important alternate and solar energy is mainly used. In order to track the radiations from the sun in an efficient manner the maximum power point tracking (MPPT) controller is used. But the existed MPPT controllers were developed based upon the ideal characteristics of constant irradiation and temperature. To overcome the above problem a practical data is considered for designing of MPPT controller which is based upon variable irradiance under various temperatures. The output obtained from the MPPT is given to the boost converter with an inverter to find the performance of an indirect vector controlled induction motor drive under different operating conditions. For inverter control, a SVM algorithm in which the calculation of switching times proportional to the instantaneous values of the reference phase voltage. It eliminates the calculation of sector and angle information. The torque ripple and the performance of induction motor drive with ideal and practical data MPPT controllers are compared under different operating conditions. An experimental validation is carried out and the comparison is made with the simulation results. Keywords: maximum power point tracking, variable irradiance, indirect vector controlled, total harmonic distortions, space vector modulation, induction motor drive and torque ripple

Total harmonic distortion analysis of inverter fed induction motor drive using neuro fuzzy type-1 and neuro fuzzy type-2 controllers

Introduction. When the working point of the indirect vector control is constant, the conventional speed and current controllers operate effectively. The operating point, however, is always shifting. In a closed-system situation, the inverter measured reference voltages show higher harmonics. As a result, the provided pulse is uneven and contains more harmonics, which enables the inverter to create an output voltage that is higher. Aim. A space vector modulation (SVM) technique is presented in this paper for type-2 neuro fuzzy systems. The inverter’s performance is compared to that of a neuro fuzzy type-1 system, a neuro fuzzy type-2 system, and classical SVM using MATLAB simulation and experimental validation. Methodology. It trains the input-output data pattern using a hybrid-learning algorithm that combines back-propagation and least squares techniques. Input and output data for the proposed technique include information on the rotation angle and change of rotation angle as input and output of produced duty ratios. A neuro fuzzy-controlled induction motor drive’s dynamic and steady-state performance is compared to that of the conventional SVM when using neuro fuzzy type-2 SVM the induction motor, performance metrics for current, torque, and speed are compared to those of neuro fuzzy type-1 and conventional SVM. Practical value. The performance of an induction motor created by simulation results are examined using the experimental validation of a dSPACE DS-1104. For various switching frequencies, the total harmonic distortion of line-line voltage using neuro fuzzy type-2, neuro fuzzy type-1, and conventional based SVMs are provided. The 3 hp induction motor in the lab is taken into consideration in the experimental validations.Вступ. Коли робоча точка непрямого векторного управління стала, традиційні регулятори швидкості та струму працюють ефективно. Проте робоча точка постійно змінюється. У ситуації закритої системи виміряна інвертором опорна напруга показує вищі гармоніки. В результаті імпульс, що подається, нерівномірний і містить більше гармонік, що дозволяє інвертору створювати більш високу вихідну напругу. Мета. У цій статті представлена методика просторової векторної модуляції (SVM) для нейронечітких систем типу 2. Продуктивність інвертора порівнюється з продуктивністю нейронечіткої системи типу 1, нейронечіткої системи типу 2 та класичної SVM з використанням моделювання MATLAB та експериментальної перевірки. Методологія. Навчається шаблон даних введення-виводу, використовуючи алгоритм гібридного навчання, який поєднує у собі методи зворотного поширення помилки та методу найменших квадратів. Вхідні та вихідні дані для запропонованої методики включають інформацію про кут повороту і зміну кута повороту як отримані вхідні і вихідні коефіцієнти заповнення. Динамічні характеристики приводу асинхронного двигуна з нейронечітким управлінням порівнюються з характеристиками звичайного SVM. При використанні нейронечіткого SVM типу 2 асинхронний двигун, показники продуктивності по струму обертаючого моменту і швидкості порівнюються з показниками приводу асинхронного двигуна з нейронечітким управлінням типу 1 та традиційного SVM. Практична цінність. Продуктивність асинхронного двигуна, створеного за результатами моделювання, досліджується з використанням експериментальної перевірки dSPACE DS-1104. Для різних частот перемикання розраховуються загальні гармонічні спотворення лінійної напруги з використанням нейронечіткого управління  типу 2, нейронечіткого управління типу 1 і традиційного SVM. Асинхронний двигун потужністю 3 л.с. у лабораторії враховується під час експериментальних перевірок

Connection between the Green functions of the supersymmetric pair of Dirac Hamiltonians

The Sukumar theorem about the connection between the Green functions of the supersymmetric pair of the Schr\"odinger Hamiltonians is generalized to the case of the supersymmetric pair of the Dirac Hamiltonians.Comment: 12 pages,Latex, no figure

Second Order Darboux Displacements

The potentials for a one dimensional Schroedinger equation that are displaced along the x axis under second order Darboux transformations, called 2-SUSY invariant, are characterized in terms of a differential-difference equation. The solutions of the Schroedinger equation with such potentials are given analytically for any value of the energy. The method is illustrated by a two-soliton potential. It is proven that a particular case of the periodic Lame-Ince potential is 2-SUSY invariant. Both Bloch solutions of the corresponding Schroedinger equation equation are found for any value of the energy. A simple analytic expression for a family of two-gap potentials is derived

PT-symmetric square well and the associated SUSY hierarchies

The PT-symmetric square well problem is considered in a SUSY framework. When the coupling strength $Z$ lies below the critical value $Z_0^{\rm (crit)}$ where PT symmetry becomes spontaneously broken, we find a hierarchy of SUSY partner potentials, depicting an unbroken SUSY situation and reducing to the family of $\sec^2$-like potentials in the $Z \to 0$ limit. For $Z$ above $Z_0^{\rm (crit)}$, there is a rich diversity of SUSY hierarchies, including some with PT-symmetry breaking and some with partial PT-symmetry restoration.Comment: LaTeX, 18 pages, no figure; broken PT-symmetry case added (Sec. 6

Static and dynamic characterization of pull-in protected CMOS compatible poly-SiGe grating light valves

status: publishe

A Mathematical Model of Heat Transfer in Partially Insulated Airways in Deep, Frozen Ground Placer Mines

Large seasonal variations in the temperature of the ventilating air in mines in the arctic cause changes in the original thermal field through heat and mass exchanges between the air and the surrounding medium. These thermal interactions have major influence on climatic quality as well as on the stability of the mine openings. Thawing of walls and roof in mine airways can be reduced by various types of thermal-insulation. Application of thermal-insulation prevents deep thawing of the rockmass surrounding an airway. In this case, the mechanism of heat transfer around a frozen, underground airway would be much different. A model of heat transfer in a deep, partially insulated airway has been developed and analyzed using finite element methods. Results of the analysis show that without any thermal control, there will be stable change in temperature around the mine airway. With different insulations on the walls of the airway, roof thawing can be reduced and in certain cases, completely eliminated

Multichannel coupling with supersymmetric quantum mechanics and exactly-solvable model for Feshbach resonance

A new type of supersymmetric transformations of the coupled-channel radial Schroedinger equation is introduced, which do not conserve the vanishing behavior of solutions at the origin. Contrary to usual transformations, these ``non-conservative'' transformations allow, in the presence of thresholds, the construction of potentials with coupled scattering matrices from uncoupled potentials. As an example, an exactly-solvable potential matrix is obtained which provides a very simple model of Feshbach-resonance phenomenon.Comment: 10 pages, 2 figure

Safety and efficacy of an oral insulin (Capsulin) in patients with early‐stage type 2 diabetes: a dose‐ranging phase IIb study

Aim This randomised, twelve-week open-label study compared the pharmacodynamic properties of different dose of regular human insulin administered in capsule form twice daily. Methods 100 persons (48 male, 52 female) with type 2 diabetes on metformin completed the study according to protocol. Mean (SD) age 48.5 (6.7) years, BMI 25.7 (2.8) kg/m2, HbA1c 8.10 (0.65) %. Subjects randomised on admission were assigned to one of three groups receiving 75iu BD of formulated regular insulin or 150iu insulin BD, or 300iu BD in enteric-coated capsules. Primary and secondary endpoints were change from baseline in HbA1c and FPG respectively. A total of 100 subjects from 15 different centres completed the study within protocol. Results The study met its primary clinical endpoint of a decrease in HbA1c ≥ 0.5% (least square mean decrease 0.52%; p = 0.004, median decrease 0.6) in the dose group receiving 150iu BD. In a subset of this population, with starting HbA1c values between 9 and 9.5%, an average decrease of 1.575% was seen. In the total population, least square mean decreases in HbA1c for groups 75iu BD and 300iu BD were -0.11% and -0.42% respectively. Mean change in FPG in the 150iu BD dose group was -18.8mg/dL (p = 0.017) and -14.8 and -2.7mg/dL for groups 75iu BD and 300iu BD respectively. A decrease of 20% for triglycerides (-40 mg/dL) was seen in the 150iu BD dose group . No significant increases in body weight were observed, and significant decreases in systolic blood pressure were seen in all groups. No serious treatment-related adverse events were recorded, and no incidence of hypoglycaemia was reported throughout the whole twelve-week study period. Conclusions Capsulin oral insulin administered twice per day at a dose of 150iu per capsule is safe, with no confirmed treatment-linked hypoglycaemic events, and results in significant decreases from baseline in HbA1c, Fasting Plasma Glucose and triglycerides