Reproduksi Identitas Mahasiswa Ternate Di YOGYAKARTA

Identity Reproductions of Ternate Student\u27s in Yogyakarta. This Study shows that identity is so important for an individual because it refers to boundaries that differs himself from others. In a group, identity will create a tradition or something that can be labeled as their ethnicity markers so they could differ themself from others. Symbols could be a typical identity characteristic to express something that important in the community as a domain to communicate in showing their existency or their identity. Moreover those symbols could connect them to another ethnics

The Effect of Dexmedetomidine on Oxidative Stress during Pneumoperitoneum

. Purpose. This study was intended to investigate the effect of dexmedetomidine on oxidative stress response in pneumoperitoneum established in rats. Methods. Animals were randomized into three groups, group S: with no pneumoperitoneum, group P: with pneumoperitoneum established, and group D: given 100 mcg intraperitoneal dexmedetomidine 30 min before establishment of pneumoperitoneum. Plasma total oxidant status (TOS), total antioxidant status (TAS), and oxidative stress index (OSI) activity were measured 30 min after conclusion of pneumoperitoneum. Results. The mean TOS level was significantly higher in group P than in the other two groups, and the TOS level was significantly higher in group D than in group S ( < 0.05). Plasma TAS level was found to be lower in group P than in the other two groups, and the TAS level was lower in group D than in group S ( < 0.05). Consequently, the OSI was significantly higher in group P than in groups D and S ( < 0.05). Conclusions. Ischemiareperfusion phenomenon that occurs during pneumoperitoneum causes oxidative stress and consumption of plasma antioxidants. Dexmedetomidine decreases oxidative stress caused by pneumoperitoneum and strengthens the antioxidant defense system

Immune-escape mutations and stop-codons in HBsAg develop in a large proportion of patients with chronic HBV infection exposed to anti-HBV drugs in Europe

Background: HBsAg immune-escape mutations can favor HBV-transmission also in vaccinated individuals, promote immunosuppression-driven HBV-reactivation, and increase fitness of drug-resistant strains. Stop-codons can enhance HBV oncogenic-properties. Furthermore, as a consequence of the overlapping structure of HBV genome, some immune-escape mutations or stop-codons in HBsAg can derive from drug-resistance mutations in RT. This study is aimed at gaining insight in prevalence and characteristics of immune-associated escape mutations, and stop-codons in HBsAg in chronically HBV-infected patients experiencing nucleos(t)ide analogues (NA) in Europe. Methods: This study analyzed 828 chronically HBV-infected European patients exposed to ≥ 1 NA, with detectable HBV-DNA and with an available HBsAg-sequence. The immune-associated escape mutations and the NA-induced immune-escape mutations sI195M, sI196S, and sE164D (resulting from drug-resistance mutation rtM204 V, rtM204I, and rtV173L) were retrieved from literature and examined. Mutations were defined as an aminoacid substitution with respect to a genotype A or D reference sequence. Results: At least one immune-associated escape mutation was detected in 22.1% of patients with rising temporal-trend. By multivariable-analysis, genotype-D correlated with higher selection of ≥ 1 immune-associated escape mutation (OR[95%CI]:2.20[1.32-3.67], P = 0.002). In genotype-D, the presence of ≥ 1 immune-associated escape mutations was significantly higher in drug-exposed patients with drug-resistant strains than with wild-type virus (29.5% vs 20.3% P = 0.012). Result confirmed by ana

Predictors of surgical complications in boys with hypospadias: data from an international registry

Background: Complications are frequently reported after hypospadias repair and there is a need to understand the factors that influence their occurrence. Methods: Data from boys with hypospadias born between 2000 and 2020 were obtained from the International Disorders of Sex Development (I-DSD) Registry. Logistic regressions, fisher’s exact tests and spearman’s correlation tests were performed on the data to assess associations between clinical factors and complication rates. Results: Of the 551 eligible boys, data were available on 160 (29%). Within the cohort, the median (range) External Masculinization Score (EMS) was 6 (2, 9). All presented with one or more additional genital malformation and 61 (38%) presented with additional extragenital malformations. Disorders of androgen action, androgen synthesis and gonadal development were diagnosed in 28 (18%), 22 (14%) and 9 (6%) boys, respectively. The remaining 101 (62%) patients were diagnosed as having non-specific 46,XY Disorders of Sex Development. Eighty (50%) boys had evidence of abnormal biochemistry, and gene variants were identified in 42 (26%). Median age at first hypospadias surgery was 2 years (0, 9), and median length of follow-up was 5 years (0, 17). Postsurgical complications were noted in 102 (64%) boys. There were no significant associations with postsurgical complications. Conclusions: Boys with proximal hypospadias in the I-DSD Registry have high rates of additional comorbidities and a high risk of postoperative complications. No clinical factors were significantly associated with complication rates. High complication rates with no observable cause suggest the involvement of other factors which need investigation

On Asymptotically F-Statistical Equivalent Sequences

By using modulus functions, we have obtained a generalization of statistical convergence of asymptotically equivalent sequences, a new non-matrix convergence method, which is intermediate between the ordinary convergence and the statistical convergence. Further, we have examined some inclusion relations related to this concept

Reduction of Listeria monocytogenes on Various Food Contact Surfaces by Listeria Phage Suspension or Electrolyzed Oxidizing Water

WOS: 000423500300003Listeria monocytogenes often contaminates food processing areas, including food contact surfaces (FCS), thus leading to occurrence of re- and cross-contamination of finished products. Effective sanitizing agents are needed to reduce Listens contamination. The phage suspension (broad host-range phage, LP-124) and electrolyzed oxidizing water (EOW, pH 2.5 and oxidation-reduction potential, ORP 1080 mV) were evaluated against L. monocytogenes on three food contact surfaces (polyethylene - PE cutting board (n = 3), stainless steel SS spoon (n = 3) and SS sieve (n = 3), and cotton towel (n = 3) directly used on ready-to-eat squid sushi). The initial L. monocytogenes concentration of 4.3 to 5.0 log(10)CFU/100 cm(2) was reduced by 1.2 to 2.4 log units and 2.7 to 3.7 log units after treatments with the phage suspension and EOW, respectively. Counts below the detection limit (< 2 log(10)CFU/100 cm(2)) were observed on all surfaces treated with EOW for 5 min contact time, suggesting a high efficacy of EOW against L. monocytogenes. The highest CFU reduction was on SS spoon (2.4 log units) treated with Listens phage and on PE cutting board (3.7 log units) treated with EOW. Both treatments are of interest for applications to inactivate L. monocytogenes on different surfaces in the food processing facilities as well as retail operations.National Research Council of ThailandNational Research Council of Thailand (NRCT); Prince of Songkla University [AGR580226S]; TRF Distinguished Research Professor Grant; Scientific and Technological Research Council of Turkey (TUBITAK) of International Postdoctoral Research Scholarship Programme [2219]This study is financially supported by The National Research Council of Thailand and Prince of Songkla University (AGR580226S). The TRF Distinguished Research Professor Grant is also acknowledged. The author E. B. yen Yilmaz is financially supported by the Scientific and Technological Research Council of Turkey (TUBITAK) of 2219-International Postdoctoral Research Scholarship Programme

Growth evaluation in children with vesicoureteral reflux

WOS: 000394629100006PubMed ID: 26377642BACKGROUND: Vesicoureteral reflux and urinary tract infection predispose children to retardation of growth, hypertension, renal scarring and renal failure. The aim of this study was to evaluate growth pattern in children with vesicoureteral reflux before and after medical/surgical treatment. METHODS: This study was a retrospective cross-sectional study. The study population included 97 children aged 0.5 to 17 years (8.8 +/- 5.5). Body weight, height and bone age of the children were measured. Weight Z score and height Z score were calculated during first visits and after medical and/or surgical treatment. Distribution, mean and standard deviation score were evaluated for the descriptive data. T-test and Mann-Whitney U test and Wilcoxon test were used for statistical analysis. RESULTS: Sixty-five percent of 97 children enrolled in this study were girls. About 48.5% of the children had unilateral and mild reflux, while 16.5% had bilateral and severe reflux. The bone age was 8.6 years. Differentiation with chronological age and bone age were not significant (P=0.294). At admission, 54.6% and 50.5% of children had negative Weight Z score and height Z score, respectively. After medical and surgical treatment, Weight Z score and height Z score were increased, however, only the increase in Weight Z score was significant (P=0.039, P=0.031, respectively). A significant reduction in bone age was found in children with renal scars compared to those without renal scars (P=0.048). CONCLUSIONS: High-grade vesicoureteral reflux had a negative impact on indices of growth in children. Medical and/ or surgical treatment had positive effect on weight gain

Pendampingan Program Penerimaan Beasiswa Perguruan Tinggi Bagi Remaja di Desa Batulayar NTB

Pelaksanaan kegiatan Sosialisasi dan Pendampingan Program Penerimaan Beasiswa Perguruan Tinggi bagi Remaja Di Desa Batulayar bertujuan untuk memberikan wawasan kepada masyarakat khususnya para remaja tantang hak untuk mendapatkan biaya pendidikan bagi mereka yang tidak mampu dan berhak mendapatkan beasiswa. Metode pelaksanaan kegiatan ini dilakukan dengan menggunakan sosialisasi dan pendampingan langsung kepada para remaja setempat. Adapun langkah langkah kegiatannya dengan melakukan persiapan (prakegiatan) sebelum melakukan kegiatan, pelaksanaan kegiatan, dan monitoring dan evaluasi kegiatan. Adapun hasil dari kegiatan tersebut para peserta dapat mengikuti kegiatan dengan antusias dengan jumlah peserta yang hadir 20 orang baik laki-laki maupun perempuan. Jumlah peminat dari 20 perserta adalah 8 orang dengan persentase 40% dan 12 orang dengan persentase 60% lagi belum berminat Selain itu, para peserta tertarik untuk mendaftarkan diri untuk menerima beasiswa dengan persyaratan yang sudah mereka miliki. Oleh karena itu, kegiatan pendampingan ini diharapkan dapat ditindaklanjuti dan dilakukan tidak hanya sasarannya di sekolah, tetapi langsung ke masyarakat