A New Theory of Lapse-Rate

A new type of vertical motion of air different from penetrative convection is discussed. For small vertical displacements the motion is assumed to be similar to that in long gravitational waves, the volume of an element remaining constant during the displacement. Vertical motion of this type is the result of differences of pressure set up in the vertical direction and the pressures on an element in the other principal directions do not alter during the process of small displacement. As a result of the change in pressure, the molecular energy of the element is altered which results in a change of temperature, and consequently in a lapse-rate

Formation of quasi-free and bubble positronium states in water and aqueous solutions

It is shown that in aqueous solutions a positronium atom is first formed in the quasi-free state, and, after 50-100 ps, becomes localized in a nanobubble. Analysis of the annihilation spectra of NaNO3 aqueous solutions shows that the hydrated electron is not involved in the positronium (Ps) formation

Determination of In-Situ Stress at Desilting Chamber of Punatsangchhu Hydroelectric Project (Bhutan), to Reconfirm Its Orientation Influenced by Topography — A Case Study

Punatsangchhu Hydroelectric Project stage-I was conceptualized in Wangdue- Phodrang district of Bhutan for harnessing the hydro-power potentiality of Punatsangchhu River. Regionally the project area is located within a part of a gneissic terrain of Tethyan Belt of Bhutan Himalayas. The project envisages construction of 195m high concrete gravity dam across the river Punatsangchhu. For Desilting chamber and Powerhouse, it is always desirable to carry out in-situ stress measurement in such huge underground openings for designing of the support types. The stability of the underground cavern gets enhanced if the long axis of the cavern is oriented along or sub-parallel to that of maximum principal stress. National Institute of Rock Mechanics, a premier Research Institute under Ministry of Mines, Government of India, carried out stress measurements at RD 100m and RD 150m inside an exploratory drift approaching towards desilting chamber with a rock cover of 100m. This test was required to freeze the orientation of desilting chamber vis. a vis. orientation of maximum compression (σH) which was found to be N 150°. As it was only 100 to 150 m away from the portal, a topography effect on the orientation of (σH) was not completely ruled out. So when the adit to Desilting chamber reached at RD 360m with a rock cover of 410m, it is necessary to carry out stress measurement at RD 360m to confirm the results of earlier tests at RD100m and RD 150m to find out the influence of topography on which the present paper is based was primarily for determination of in-situ stress measurements. The stress orientation as evaluated at RD 360m reconfirms the orientations revealed from earlier stress measurements at RD 100 and RD 150m.Thus it is recommended to freeze the direction of Desilting chamber along N 150°. It also confirms that the earlier stress measurement results do not suffer from topography related influence

Prevalence of subclinical hypothyroidism in children and adolescents of northern Andhra Pradesh population and its association with hyperlipidemia

Background: The thyroid dysfunction particularly, subclinical hypothyroidism (SCH) is quite a common clinical condition in paediatric population but there is limited data available regarding its prevalence in children and adolescents in our population. The present study was aimed to know the prevalence of thyroid dysfunction particularly SCH in children and adolescents of northern Andhra Pradesh population and its association with hyperlipidemia.Methods: A retrospective study of 600 subjects (Children=272, Adolescents=328) between 6-19 years of age were included and the following parameters were examined: age, sex, total triiodothyronine (tT3), total tetraiodothyronine (tT4), thyroid stimulating hormone (TSH), total cholesterol, triglycerides (TGL), LDL and HDL cholesterol. The subjects were divided into group I and group II on the basis of age (in years), subjects between 6- ≤12 years age were grouped as group I and 12-≤19 years were as group II.Results: Out of 272 children and 328 adolescents studied, the prevalence of thyroid dysfunction was found to be 9.9% and 10.4 % respectively. The prevalence of subclinical hypothyroidism in children was 7.7% where as 4.9% in adolescents. In both the groups, females were predominantly affected with thyroid dysfunction as compared to males. Significantly elevated serum levels of total cholesterol, TSH and TGL were observed in SCH subjects when compared to euthyroid subjects (p<0.05). Statistically significant lower levels of HDL cholesterol were found in SCH as compared to euthyroids (p<0.05). However, no difference was noticed in the levels of total T3, total T4 and LDL cholesterol between SCH and euthyroids.Conclusions: The prevalence of thyroid dysfunction was found to be 10.2% in study population. SCH was observed in 7.7 % and 4.9% respectively in children and adolescent groups. Subclinical hypothyroidism (SCH) was the most predominant thyroid dysfunction found in our studied population with a prevalence of 6.2% (both children and adolescents). Correction of thyroid dysfunction particularly SCH in early childhood is highly essential to prevent the impairment of psychomotor and cognitive development

Clinical and etiological spectrum of prolonged fever and special reference to HIV patients at a tertiary care centre

Background: Prolonged fever is a diagnostic challenge and will tend to remain so in times to come because of the changing spectrum of etiologies and influence of technology, environmental changes, and many other ill-understood factors which influence the etiological spectrum. Prolonged fever is also undergoing change in its duration. The aim of the present was study to determine the etiologies of prolonged fever in patients in India and to evaluate the clinical and etiological relationship between the diagnosis and patient’s laboratory data.Methods: Patients aged more 13 years with fever >38.3ºC for more than three weeks without apparent source after preliminary investigations were included prospectively over a period of twenty two months. Fever duration, symptom, signs, laboratory investigations and final diagnosis were recorded. The distribution of etiologies and age, fever duration, laboratory examinations, and associated symptoms and signs were analyzed.Results: Out of total of 86 patients were enrolled, fifty one (59.3%) were men. The median age was 28 years (range, 13-65 yr). Among 86 patients, diagnosis could be made in only 69 (80.2%) patients. Infections, neoplasms, NIIDs, miscellaneous causes were responsible for prolonged fever in 42 (48.8%), 18 (20.9%), 6 (7%), and 3 (3.5%) patients respectively. Seveteen (19.8%) cases remained undiagnosed, even after relevant investigations, six of them recovered spontaneously. Tuberculosis (TB) was the cause of prolonged fever in 21 (24.4%) patients.Conclusions: Infections, amongst which tuberculosis, remain the major cause of prolonged fever and its subset: fever of unknown origin (FUO), in this country. The percent of undiagnosed cases appears to be identical worldwide

Effective chiral-spin Hamiltonian for odd-numbered coupled Heisenberg chains

An $L \times \infty$ system of odd number of coupled Heisenberg spin chains is studied using a degenerate perturbation theory, where $L$ is the number of coupled chains. An effective chain Hamiltonian is derived explicitly in terms of two spin half degrees of freedom of a closed chain of $L$ sites, valid in the regime the inter-chain coupling is stronger than the intra-chain coupling. The spin gap has been calculated numerically using the effective Hamiltonian for $L=3,5,7,9$ for a finite chain up to ten sites. It is suggested that the ground state of the effective Hamiltonian is correlated, by examining variational states for the effective chiral-spin chain Hamiltonian.Comment: 9 Pages, Latex, report ICTP-94-28

Deep Learning for Forecasting Stock Returns in the Cross-Section

Many studies have been undertaken by using machine learning techniques, including neural networks, to predict stock returns. Recently, a method known as deep learning, which achieves high performance mainly in image recognition and speech recognition, has attracted attention in the machine learning field. This paper implements deep learning to predict one-month-ahead stock returns in the cross-section in the Japanese stock market and investigates the performance of the method. Our results show that deep neural networks generally outperform shallow neural networks, and the best networks also outperform representative machine learning models. These results indicate that deep learning shows promise as a skillful machine learning method to predict stock returns in the cross-section.Comment: 12 pages, 2 figures, 8 tables, accepted at PAKDD 201

ROLE OF CLINICAL PHARMACIST IN ASSESSMENT OF DRUG RELATED PROBLEMS OF CARDIOVASCULAR AGENTS IN DEPARTMENT OF CARDIOLOGY IN A TERTIARY CARE HOSPITAL – A PROSPECTIVE OBSERVATIONAL STUDY

In total of 173 prescriptions of the patient, the total number of 329 drug interactions (DIs) was found, in which the 240 interactions were found in male and 89 in the female bearing 72.90% and 27.10%, respectively. Patient was of various age groups, in which the maximum frequency was seen in the age group of 61–70 years having 105 interactions bearing the percentage of 31.9%. According to the participation of different age group of the male and female with their corresponding age. The participation of male is high having frequency of 240 (72.9%) than female participation of frequency 89 (27.1%). The participation of male in the age group of 61–70 years is 83 and the female is 40 in the age group of 51–60 years. Potential DIs (PDIs) were categorized based on the gender. In that compared to 13 (40.6) females, males 19 (59.4%) were found to have more PDIs. Our study is more PDIs in adult patients. Because in adults lacking of nutrition’s and in elderly patients multiple prescribers, multiple drugs and multiple diseases. The number of potential drug-DI (PDDI) increased with an increase in the number of drugs prescribed. The numbers of drug prescribed increase with age. This DI has a potential to increase or decrease the therapeutic effect or to increase the risk of adverse drug reaction. An increased awareness of PDDIs, rational coprescription of drugs, and a close monitoring of patients in whom these drugs are prescribed are recommended. The recommendation is based on the special monitoring and the perspiration of the clinical pharmacist. The DI observed in the geriatric patient is more severe and common in compared to the other groups of study. The geriatric patient is physiological disability in correspond with the first-pass metabolism and the presence of the other diseases which also enables the multiple prescriptions causing polypharmacy. The gender specification also the cause of the interaction, the female is more prone to the DI due to the hormonal distribution in the body and inability of the physiological function to absorb and the distribution. The special training should be provided to the pharmacist for looking forward of the geriatric patient and female patient. The training regarding the prescription their adherence, use, toxicity, and dosage regimen is being properly enabled in the training for the practical application. This study helps to know the different interaction related to the cardiovascular agent with own class of the drug and the other class of drugs used therapeutically to care the disease

Enhancement in electron and ion temperatures due to solar flares as measured by SROSS-C2 satellite

The observations on the ionospheric electron and ion temperatures (T<sub>e</sub> and T<sub>i</sub>) measured by the RPA payload aboard the SROSS-C2 satellite have been used to study the effect of solar flares on ionospheric heating. The data on solar flare has been obtained from the National Geophysical Data Center (NGDC) Boulder, Colorado (USA). It has been found that the electron and ion temperatures have a consistent enhancement during the solar flares on the dayside Earth's ionosphere. The estimated enhancement for the average electron temperature is from 1.3 to 1.9 times whereas for ion temperature it is from 1.2 to 1.4 times to the normal days average temperature. The enhancement of ionospheric temperatures due to solar flares is correlated with the diurnal variation of normal days' ionospheric temperatures. The solar flare does not have any significant effect on the nightside ionosphere. A comparison with the temperature obtained from the IRI-95 model also shows a similar enhancement