The F waves study in young healthy individuals

Background: The F wave is a CMAP (compound muscle action potential) evoked by a supramaximal stimulation of a motor nerve. F waves are particularly useful for the diagnoses of polyneuropathies at an early stage and proximal nerve lesions.Methods: Healthy males (n=64) and females (n=26) medical students of BPKIHS with age 20 to 24 years were enrolled. Anthropometric parameters; F wave latencies, persistence and chronodispersion of bilateral median, ulnar and tibial nerves were recorded in Neurophysiology Lab II of BPKIHS. Descriptive analysis was done.Results: Mean age, height and weight of the subjects were 21.64±1.19 years, 165.61±5.4cms and 64.07±5.5kg. Mean minimum F wave latencies (ms) of right median, ulnar and tibial nerves were 24.09±1.95, 24.02±1.76, 44.34±3.02 while on the left side were 23.92±1.96, 24.11±1.92, 44.07±2.83 respectively. F persistence was above 80%. F chronodispersion (ms) for right and left median, ulnar and tibial nerves were 2.77±0.70, 2.79±0.65, 2.71±0.67, 2.80±0.56, 3.48±0.73 and 3.45±0.64 respectively.Conclusions: Maximum and minimum F wave latencies, F chronodispersion and F persistence were derived for both sexes in an age group of 20-24 years

Evaluation of Onion Genotypes for Growth and Bulb Yield in Mid Hill of Nepal

Experiments were conducted at Horticulture Research Division (HRD), Khumaltar, Lalitpur; and Horticulture Research Station (HRS), Kimugaun, Dailekh in 2017/18 to evaluate the high yielding open pollinated genotypes of onion in mid hills of both locations.  Five onion genotypes namely AVON-1016, AVON-1027, AVON-1028, AVON-1052, AVON-1074 and AVON-1103 received from Asian Vegetable Research and Development Centre were evaluated with local check variety and recommended variety Red Creole in both locations in randomized complete block design with 4 replications. The main objective of the experiment is to findout the high yielding open pollinated onion genotypes for mid hill condition.The pooled analysis of data over locations showed significant differences on plant height, neck diameter, bulb diameter, weight of bulbs and adjusted bulb yield per hectare.   Introduced genotypes AVON 1027 (38.83 t/ha), AVON 1052 (31.97 t/ha) and AVON 1028 (31.48 t/ha) produced significantly higher yield than recommended and commercially cultivated check variety Red Creole (27.04 t/ha). Therefore the genotype AVON 1027 can be selected as the best genotype for growing in mid hills of Nepa

Pattern of ocular morbidity in pediatrics age group in a tertiary centre in western Nepal

Introduction: Ocular morbidities are importantbecause of their impact on child’s development,education and future work. Ocular morbidities in children may not be diagnosed and treated in time due to inability to express their problems which leads to amblyopia by the time they can express it. This study was conducted with an objective to determine the pattern of ocular morbidity in children less than and equal to 14 years of age presenting in the Outpatient Department (OPD) of Gandaki Medical College, Pokhara. Materials/ Methods: This is a cross sectional observational study where we reviewed the profile of all of all patients of age group equal to or less than 14 years entering eye OPD from September 2016 to September 2018 for eye examination. Result: A total of 1471 patients presented to eye department of GMC. The mean age of the patient was 8.25 ±4.24 years among which 57.8% were males and 42.2% were females. Maximum number of the patients were in age group 11 to 14 years (38.1%) while minimum number of the patients were in the age group <1 year(10.6%).Conjunctival disorders (23.9%) was the most common ocular morbidity followed by refractive error in (18.2%), miscellaneous conditions (10.4%), eyelid diseases (8.6%), lacrimal system diseases (7.8%). Conclusion: Thestudy gives a picture and pattern of ocular diseases in pediatrics age group which not only helps in early diagnosis and treatment of ocular diseases but also in decreasing the magnitude of childhood blindness and amblyopia

Herpetofauna of a Ramsar Site: Beeshazar and Associated Lakes, Chitwan National Park, Nepal

Global Challenges (FSW

Nonlinear lattice dynamics as a basis for enhanced superconductivity in YBa2Cu3O6.5

THz-frequency optical pulses can resonantly drive selected vibrational modes in solids and deform their crystal structure. In complex oxides, this method has been used to melt electronic orders, drive insulator to metal transitions or induce superconductivity. Strikingly, coherent interlayer transport strongly reminiscent of superconductivity can be transiently induced up to room temperature in YBa2Cu3O6+x. By combining femtosecond X-ray diffraction and ab initio density functional theory calculations, we determine here the crystal structure of this exotic non-equilibrium state. We find that nonlinear lattice excitation in normal-state YBa2Cu3O6+x at 100 K causes a staggered dilation/contraction of the Cu-O2 intra/inter- bilayer distances, accompanied by anisotropic changes in the in-plane O-Cu-O bond buckling. Density functional theory calculations indicate that these motions cause dramatic changes in the electronic structure. Amongst these, the enhancement in the dx2-y2 character of the in-plane electronic structure is likely to favor superconductivity.Comment: 28 pages, including Supplemen

Pattern of Drugs and Therapeutic Agents Exposure among Pediatric Inpatients in the Fatima University Medical Center

Background: Drugs and therapeutic agents exposure is essentially universal for persons, young and old in the Philippines. In the hospital, many drugs and therapeutic agents are being given to the patients according to severity of the illness. The evidence has suggested that complex medication combination increase the risk for adverse drug events. The most common results of many drugs and therapeutic agents are increased adverse drug reactions, drug-drug interactions and higher costs. Objectives: To assess the prevalence and patterns of exposure to drugs and therapeutic agents among pediatric inpatients. Methods: Study Design: Retrospective study. Setting: Pediatric inpatients in the Fatima University Medical Center. Patients: A total of 1075 patients younger than 19 years, excluding healthy newborn, hospitalized in 2011, representing a part of pediatric inpatients in the Philippines. Results: The most common exposure was with D5.3NaCl, paracetamol, cefuroxime, salbutamol, zinc sulphate. Most of the pediatric inpatients received five or less number of medication varied by age and length of stay in the hospital. Pediatric inpatients were exposed to numerous drugs and therapeutic agents, especially patients with dengue III. Conclusions: A large portion of pediatric inpatients are exposed to numerous drugs and therapeutic agents, especially patients with Dengue III.  J-GMC-N | Volume 11 | Issue 01 | January-June 2018, Page: 23-2

Distribution of Dental Diseases and Treatment Delivered amongst Patients Visiting Dental Outpatient Department at Gandaki Medical College, Nepal

Introduction: A study of dental diseases amongst patients attending dental outpatient department (OPD) helps us plan a preventive, and/or a definitive dental treatment. Objectives: To find out the distribution of dental diseases amongst patients visiting dental OPD at College of Dental Surgery, Gandaki Medical College (GMC), Pokhara, Nepal. Methods: The present study was a hospital based cross sectional descriptive study carried out during a period of one year extending from 1st February 2016 to 31st January 2017. A total of 3052 patients attending the dental OPD were included in the study. The distribution of dental diseases according to sex, age and diagnosis were collected and analyzed. Additionally, frequency distribution of treatments provided to the patients was observed. Results: Dental caries was the most prevalent dental disease (64.41%) followed by gingivitis (13.04%). The prevalence of dental caries was significantly higher in females (Females 56.91% vs. males 43.08%, P <0.05). Conversely, the prevalence of maxillofacial injuries (85.06%), dental impactions (72%), and malocclusion (53.88%) were significantly more common in male patients (P <0.05). The age group <19 years comprised 23.98 % of patients who visited the dental OPD, and the dental caries was most prevalent (27.10%) in the age group. The order of more frequent dental treatments was root canal treatment (18.84%), tooth extraction (18.44%), dental restoration (10.48%), and scaling (9.20%). Conclusions: The most prevalent dental disease was dental caries and it was more prevalent in females than in males. The most common age group reporting to Dental OPD was <19 years.  J-GMC-N | Volume 11 | Issue 01 | January-June 2018, Page: 29-3

Prenatal and Perinatal Risk Factors for Autism at National Children’s Hospital

Background: Autism, or autism spectrum disorder, refers to a broad conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication. Objectives: To determine the demographic profile of patients diagnosed with ASD, determine the significant prenatal and perinatal risk factors associated with ASD. Results: A total of 116 subjects were included in the study with 58 cases and 58 controls. They belong to the age ranging from 4 to 16 years old. Every case had a confirmed diagnosis of autism at NCH. There was a significant association noted between neonatal jaundice, nulliparity (OR=2.38; 95% CI, 0.85-6.8) and family history of autism (OR=5.30; 95% CI, 1.29-25.1) with ASD. Exposure to x-ray, medical problems, medicine intake and maternal complications during pregnancy were not significantly associated with ASD with OR 0.74; 95% CI, (0.12-4.15), OR 1.00; 95% CI (0.38-2.61), OR1.49; 95% CI, (0.63-3.53), and OR 1.27; 95% CI, (0.28-6.05), respectively. Conclusion: The current study indicates that the only significant predictor of ASD is a family history of autism. However, neonatal jaundice, maternal age of >40 years old, smoking during pregnancy and nulliparity showed a trend towards being risk factors for ASD. None of the other prenatal and perinatal characteristics significantly predicts ASD

Magnetic Properties of Ab initio Model for Iron-Based Superconductors LaFeAsO

By using variational Monte Carlo method, we examine an effective low-energy model for LaFeAsO derived from an ab initio downfolding scheme. We show that quantum and many-body fluctuations near a quantum critical point largely reduce the antiferromagnetic (AF) ordered moment and the model not only quantitatively reproduces the small ordered moment in LaFeAsO, but also explains the diverse dependence on LaFePO, BaFe2As2 and FeTe. We also find that LaFeAsO is under large orbital fluctuations, sandwiched by the AF Mott insulator and weakly correlated metals. The orbital fluctuations and Dirac-cone dispersion hold keys for the diverse magnetic properties.Comment: 4 pages, 4 figure

Limit on Continuous Neutrino Emission from Neutron Stars

The timing data of the binary pulsar PSR1913+16, are used to establish an upper limit on the rate of continuous neutrino emission from neutron stars. Neutrino emission from each of the neutron stars of the binary system, increases the star binding energy and thus translates to a decrease in their masses. This in turn implies an increase with time of the binary period. Using the pulsar data we obtain an upper limit on the allowed rate of mass reduction : $| \dot{M}| <1.1 \times 10^{-12} yr^{-1} M$, where $M$ is the total mass of the binary. This constrains exotic nuclear equations of state that predict continuous neutrino emissions. The limit applies also to other channels of energy loss, e.g. axion emission. Continued timing measurements of additional binary pulsars, should yield a stronger limit in the future.Comment: 5 pages, Added a section on energy transport in the neutron star, JHEP publishe