4 research outputs found
Sistema y método de evaluación de la protección anticorrosiva de recubrimientos orgánicos
Sistema y método de evaluación de la protección anticorrosiva
de recubrimientos orgánicos con medios de medida
(1) que incluyen un potenciostato/galvanostato, y un
equipo de impedancias Zahner, un analizador de frecuencias
de respuesta (2) conectado a los primeros medios de
medida (1), y una unidad lógica de procesamiento (5) para
el control y programación del ensayo, conectándose los
primeros medios de medida (1) a una celda electroquÃmica
(4) dentro de una caja de Faraday (3). La celda electroquÃmica
(4) tiene al menos tres electrodos, una plancha
pintada a ensayar (42), y un electrolito conductor de iones,
consistiendo los tres electrodos en un primer electrodo de
referencia (46) Ag/AgCl, un segundo contraelectrodo (44,
50) de geometrÃa circular con orificio central y espesor laminado,
o bien definiendo un cilindro, y un tercer electrodo de trabajo (48) o sustrato de la plancha pintada (42).MEDICIONES Y CORROSIÓN SA, Consejo Superior de Investigaciones CientÃficas (España)B1 Patente con informe sobre el estado de la ténic
Design of nanostructured siloxane-gelatin coatings: Immobilization strategies and dissolution properties
Owing to the outstanding service life of metallic prostheses, a substantial effort has been put into their surface modification to improve biocompatibility and reduce metallic ion diffusion. To satisfy these requirements, the coating materials obtained using the sol-gel method, with its wide range of tuning properties, have been extensively explored. The well-known biocompatibility of these materials makes them good candidates for different biomedical applications. We designed a series of siloxane-gelatin hybrids to be used as coatings for metallic implants or in controlled delivery systems. Two different matrixes were designed based on methyltrimethoxysilane (MTMOS), tetraethoxysilane (TEOS) and 3-glycidoxypropyltrimethoxysilane (GPTMS) alkoxysilane precursors. In one hybrid coating gelatin was physically entrapped and in the other it was linked to the siloxane network by covalent bonds. Synthesis parameters were established by studying the sol-gel reaction using 29Si nuclear magnetic resonance (29Si NMR), which also allowed quantification of the network connectivity. Dissolution and degradation studies showed the effectiveness of GPTMS as a covalent coupling agent between the silica and gelatin phases; it increased the stability of the coatings in aqueous media. The aim of this study was to design a set of hybrid materials with highly tailorable properties, suitable for their potential biomedical application
Estudio de materiales superadsorbentes con aplicaciones textiles para la mejora del confort térmico
Research work was undertaken with the aim
of developing a garment containing adsorbent
materials, which are characterised by high
adsorption capacity, and could be applied in
a textile to absorb user's sweat, in order to
eliminate possible external sweat spots as well
as improving user thermal comfort. The research
covered the characterization of the employed
adsorbent materials, the development of adequate
prototype garments and their testing on a
subject. Two prototypes, in the form of a vest,
containing different adsorbent materials were
made. Several types of adsorbent materials were
evaluated. SG B 127 and Rhapid Sheet Silica Gel
were selected as the best options to apply in the
sweat-absorbing textile of the vest. The user, an
orchestra director, wearing the prototype under
its suit was exposed to 30ºC/80% RH ambient
in a climatic chamber and performed for 35 min,
simulating real working conditions. Microclimate
temperatures, humidity at most interesting points under the suit were recorded. Simultaneously, heart rate and thermal
sensation votes were also recorded. The experimental results showed
that the prototypes had the capacity to absorb the exuded water
vapor and fully eliminate sweat spots. However, the prototype turned
out to generate a considerable warming effect on the covered body
areas. This effect, mainly due to the reaction heat released during
the adsorption process, was expected but it turned out to be more
intensive than thought.El objetivo del proyecto ha sido el
desarrollo de un relleno de material
superadsorbente que pueda ser
insertado en la confección de prendas
de vestir. La primera parte del proyecto
se centró en la realización de ensayos
de laboratorio para determinar la
capacidad instantánea de adsorción de
diferentes materiales superadsorbentes
y su variación en el tiempo.
A partir de los resultados de estos
ensayos se calcularon y diseñaron
dos prototipos de chaleco con los
materiales adsorbentes de mejores
caracterÃsticas. Finalmente, se llevó a
cabo la caracterización experimental
de los prototipos desarrollados con
directores de orquesta, en condiciones
controladas, realizando actividad en
condiciones simuladas de trabajo
Osseointegration mechanisms: a proteomic approach
The prime objectives in the development of biomaterials for dental applications are to improve the quality of osseointegration
and to short the time needed to achieve it. Design of implants nowadays involves changes in the surface characteristics to
obtain a good cellular response. Incorporating osteoinductive elements is one way to achieve the best regeneration possible
post-implantation. This study examined the osteointegrative potential of two distinct biomaterials: sandblasted acid-etched
titanium and a silica sol–gel hybrid coating, 70% MTMOS-30% TEOS. In vitro, in vivo, and proteomic characterisations of
the two materials were conducted. Enhanced expression levels of ALP and IL-6 in the MC3T3-E1 cells cultured with coated
discs, suggest that growing cells on such surfaces may increase mineralisation levels. 70M30T-coated implants showed
improved bone growth in vivo compared to uncoated titanium. Complete osseointegration was achieved on both. However,
coated implants displayed osteoinductive properties, while uncoated implants demonstrated osteoconductive characteristics.
Coagulation-related proteins attached predominantly to SAE-Ti surface. Surface properties of the material might drive the
regenerative process of the affected tissue. Analysis of the proteins on the coated dental implant showed that few proteins
specifically attached to its surface, possibly indicating that its osteoinductive properties depend on the silicon delivery from
the implant