La pericolosità sismica in Italia e nell’area dello stretto di Messina

Le stime probabilistiche della pericolosità sismica sono alla base di qualsiasi politica di prevenzione dei danni da terremoto, sia perché utilizzate per definire le aree prioritarie per interventi di riduzione del rischio sismico, sia perché su di esse si basa la normativa tecnica per le costruzioni. Eppure, nonostante la loro importanza, non esiste una procedura standard universalmente riconosciuta per definire con precisione la pericolosità sismica di un’area

Seismic hazard assessment in terms of macroseismic intensity for the Italian area

A seismic hazard map, in terms of macro seismic intensity with 10% probability of exceedance in 50 years, is proposed for the Italian territory. The input elements used to evaluate the seismic hazard are: the seismogenic zoning ZS9 (Meletti et al., 2007), the earthquake catalogue CPTI04 (Gruppo di lavoro CPTI04, 2004) and intensity attenuation relationships. The first two elements and the historical and statistical completeness of the catalogue are those used in the national seismic hazard map for Italy MPS04 (Gruppo di Lavoro MPS, 2004). Two intensity attenuation models are used: 1) one national relationship obtained with a new approach by Pasolini et al. (2006) and a relationship for the Etna volcanic zone proposed by Azzaro et al. (2006) 2) a set of regional relationships derived from a previous cubic model (Berardi et al., 1993) which is recalibrated in the present study using the macro seismic intensity database DBMI04 (Stucchi et al., 2007), which was used for compiling CPTI04. The computer code adopted to evaluate the seismic hazard, with the elements cited above, is SeisRisk III (Bender and Perkins, 1987), which has been modified within this study to incorporate the aleatory variability of the ground motion (macroseismic intensity). A logic-tree framework allowed to explore some possible alternatives of epistemic character. The seismic hazard map obtained in terms of intensity was subsequently transformed into PGA by means of a linear relation between intensity and PGA, in order to compare it with the recently national seismic hazard map MPS04

Seismic hazard in the Po Plain and the 2012 Emilia earthquakes

The Emilia earthquakes of May 20, 2012 (ML 5.9, INGV; MW 6.11, http://www.bo.ingv.it/RCMT/) and May 29, 2012 (ML 5.8, INGV; MW 5.96, http://www.bo.ingv.it/RCMT/) struck an area that in the national reference seismic hazard model [MPS04; http://zonesismiche.mi.ingv.it, and Stucchi et al. 2011] is characterized by expected horizontal peak ground acceleration (PGA) with a 10% probability of exceedance in 50 years that ranges between 0.10 g and 0.15 g (Figure 1), which is a medium level of seismic hazard in Italy. The strong impact of the earthquakes on a region that is not included among the most hazardous areas of Italy, and the ground motion data recorded by accelerometric networks, have given the impression to the population and the media that the current seismic hazard map is not correct, and thus needs to be updated. Since the MPS04 seismic hazard model was adopted by the current Italian building code [Norme Tecniche per le Costruzioni 2008, hereafter termed NTC08; http://www.cslp. it/cslp/] as the basis to define seismic action (the design spectra), any modification to the seismic hazard model would also affect the building code. The aim of this paper is to briefly present the data that support the seismic hazard model in the area, and to perform some comparisons between recorded ground motion with seismic hazard estimates and design spectra. All of the comparisons presented in this study are for the horizontal components only, as the Italian hazard model did not perform any estimates for the vertical component

Yeasts and moulds contaminants of food ice cubes and their survival in different drinks

Aims: To evaluate the levels of unicellular and filamentous fungi in ice cubes produced at different levels and to determine their survival in alcoholic beverages and soft drinks. Methods and Results: Sixty samples of ice cubes collected from home level (HL) productions, bars and pubs (BP) and industrial manufacturing plants (MP) were investigated for the presence and cell density of yeasts and moulds. Moulds were detected in almost all samples, while yeasts developed from the majority of HL and MP samples. Representative colonies of microfungi were subjected to phenotypic and genotypic characterization. The identification was carried out by restriction fragment length polymorphism (RFLP) analysis of the region spanning the internal transcribed spacers (ITS1 and ITS2) and the 5·8S rRNA gene. The process of yeast identification was concluded by sequencing the D1/D2 region of the 26S rRNA gene. The fungal biodiversity associated with food ice was represented by nine yeast and nine mould species. Strains belonging to Candida parapsilosis and Cryptococcus curvatus, both opportunistic human pathogens, and Penicillium glabrum, an ubiquitous mould in the ice samples analysed, were selected to evaluate the effectiveness of the ice cubes to transfer pathogenic microfungi to consumers, after addition to alcoholic beverages and soft drinks. All strains retained their viability. Conclusions: The survival test indicated that the most common mode of consumption of ice cubes, through its direct addition to drinks and beverages, did not reduce the viability of microfungi. Significance and Impact of the Study: This study evidenced the presence of microfungi in food ice and ascertained their survival in soft drinks and alcoholic beverages

Gold-Silver Catalysts: Ruling Factors for Establishing Synergism

DPU and SOL immobilisation have been used to prepare 1 %AuAg/TiO2 with internal ratio 1 : 1 and 4 : 1 which have been studied as fresh, calcined in air at 300 \ub0C and reduced at 550 \ub0C in H2. TEM-EDS, XPS, UV-Vis and CO-DRIFT allowed to characterize the samples in terms of particle size, particle composition, exposure and oxidation state of metals. Correlating these characteristics to the catalytic behaviour we concluded that only Au-rich catalysts show synergistic effect, silver in bimetallic systems appears more resistant to oxidation than in monometallic one, thermal treatment enhances the SMSI thus producing (regardless to the post-treatment) almost the same amount of Au\u3b4+ and also Ag\u3b4+. Catalysts prepared by DPU (calcined in air or reduced in H2) are more active than SOL (fresh or calcined) probably due to the higher presence of gold at the surface

Treatment of Hepatitis C virus genotype 3 infection with direct-acting antiviral agents

Hepatitis C virus (HCV) genotype 3 is responsible for 30.1% of chronic hepatitis C infection cases worldwide. In the era of directacting antivirals, these patients have become one of the most challenging to treat, due to fewer effective drug options, higher risk of developing cirrhosis and hepatocellular carcinoma and lower sustained virological response (SVR) rates. Currently there are 4 recommended drugs for the treatment of HCV genotype 3: pegylated interferon (PegIFN), sofosbuvir (SOF), daclatasvir (DCV) and ribavirin (RBV). Treatment with PegIFN, SOF and RBV for 12 weeks has an overall SVR rate of 83-100%, without significant differences among cirrhotic and non-cirrhotic patients. However, this therapeutic regimen has several contra-indications and can cause significant adverse events, which can reduce adherence and impair SVR rates. SOF plus RBV for 24 weeks is another treatment option, with SVR rates of 82-96% among patients without cirrhosis and 62-92% among those with cirrhosis. Finally, SOF plus DCV provides 94-97% SVR rates in non-cirrhotic patients, but 59-69% in those with cirrhosis. The addition of RBV to the regimen of SOF plus DCV increases the SVR rates in cirrhotic patients above 80%, and extending treatment to 24 weeks raises SVR to 90%. The ideal duration of therapy is still under investigation. For cirrhotic patients, the optimal duration, or even the best regimen, is still uncertain. Further studies are necessary to clarify the best regimen to treat HCV genotype 3 infection491

Gli effetti dell’introduzione della nuova mappa di pericolosità sulla valutazione del rischio sismico in Italia.

L’introduzione di una versione aggiornata della mappa di pericolosità sismica, definita per diversi periodi di ritorno e per svariati valori di ordinate spettrali, porta inevitabilmente a dei cambiamenti sul livello di rischio sismico del costruito italiano. Poiché la relazione tra domanda e capacità non è lineare per tutto il range di periodi di vibrazione strutturale, è necessario valutare il cambiamento del livello di rischio sismico calcolando esplicitamente la vulnerabilità sismica di strutture esistenti con diversi periodi di vibrazione, per diversi stati limite e considerando sia la nuova che la precedente definizione di pericolosità. Nel presente lavoro è stato eseguito un primo studio degli effetti che l’introduzione di mappe aggiornate della pericolosità sismica potrebbe avere sulla valutazione dei livelli di rischio sismico nel territorio italiano. Le caratteristiche generali del costruito sono state ricavate dai dati del 14° Censimento Generale della Popolazione e delle Abitazioni (ISTAT 2001), mentre una procedura probabilistica di valutazione sismica per edifici esistenti a scala urbana è stata impiegata per stimare la capacità. Sono stati considerati tutti i tre stati limite prescritti dall’Ordinanza (danno lieve, danno severo, collasso) in corrispondenza dei rispettivi valori di domanda, così come il cambiamento delle forme spettrali in funzione della localizzazione e del periodo di ritorno. I risultati dimostrano che la nuova mappa di pericolosità sismica porta a dei livelli di rischio sismico più realistici e meno allarmanti, rendendo leggermente meno gravoso, anche se non privo di problematiche, il panorama attuale di rischio in Italia