163 research outputs found
Psychedelic Therapy Versus Antidepressants for Treating Chronic Depression
More than 18 million people in the United States suffer from depression, making it the number one cause of disability. Depression is the primary reason why every 14 minutes someone dies from suicide, creating an epidemic. Since the introduction of selective serotonin reuptake inhibitors (SSRI) such as Prozac 30 years ago, only minor variations of selective serotonin reuptake inhibitors (SSRI) and serotonin-norepinephrine reuptake inhibitors (SNRI) antidepressants have been developed. Unfortunately, over 50% of individuals do not respond to antidepressants. In order to fight back against the mental health epidemic, a need exists to innovate new ways to fight chronic depression. In addressing the potential benefit that psychedelic therapy has on patients suffering from depression the following evidence-based PICOT question was addressed: In patients with chronic depression, does the use of psychedelic therapy, compared to patients prescribed antidepressants, improve mood and signs of depression? The search strategy method examined research articles in CINAHL and PsycINFO, focusing on the keywords “psychedelic therapy”, “depression”, “hallucinogens\u27\u27, “psilocybin”, and “LSD”. Initially the search produced 40 articles, and was then narrowed by concentrating on peer reviewed articles between 2017 and 2022. Articles omitting key words were excluded. The literature suggests that continued utilization of psychedelic therapies to treat depressive disorders can significantly decrease symptoms and feelings of depression for some patients
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Alternative Donor--Acceptor Stacks from Crown Ethers and Naphthalene Diimide Derivatives: Rapid, Selective Formation from Solution and Solid State Grinding
Self assembling {pi}-conjugated molecules into ordered structures are of increasing interest in the field of organic electronics. One particular example is charge transfer complexes containing columnar alternative donor-acceptor (ADA) stacks, where neutral and ionic ground states can be readily tuned to modulate electrical, optical, and ferroelectrical properties. Aromatic-aromatic and charge transfer interactions have been the leading driving forces in assisting the self-assembly of ADA stacks. Various folding structures containing ADA stacks were assembled in solution with the aid of solvophobic or ion-binding interactions. Meanwhile, examples of solid ADA stacks, which are more appealing for practical use in devices, were obtained from cocrystalization of binary components or mesophase assembly of liquid crystals in bulk blends. Regardless of these examples, faster and more controllable approaches towards precise supramolecular order in the solid state are still highly desirable
Homonuclear decoupling for spectral simplification of carbon-13 enriched molecules in solution-state NMR enhanced by dissolution DNP
Conformational Dynamics of a Seven Transmembrane Helical Protein Anabaena Sensory Rhodopsin Probed by Solid-State NMR
Das reale Trennvermögen gas-chromatographischer Säulen - Beurteilung und Grenzen ihrer Leistungsfähigkeit
ChemInform Abstract: GASCHROMATOGRAPHISCHE ZWEIKANAL-DIFFERENZANALYSE ZUR OLEFINBESTIMMUNG IN TECHNISCHEN C4- BIS C7-KOHLENWASSERSTOFFGEMISCHEN
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