Role of Age and Sex in the Effects of Repeated Methamphetamine Exposure on Hedonic Tone in Sprague Dawley Rats

Anhedonia is defined as a reduced or complete loss of pleasure from a previously pleasurable stimulus, and it is comprised of two dimensions: Hedonic anhedonia consists of a distinct loss of pleasure in consumption of a normally pleasurable stimulus. Motivational anhedonia involves the goal directed behavior to obtain a reward. Withdrawal induced anhedonia following use of methamphetamine (METH) is thought to contribute to relapse behaviors1,2 . The anhedonic effects of drug withdrawal largely depend on dose, frequency, and the duration of drug exposure4,5,6. The role of sex and age of exposure in this context has yet to be elucidated

Coupling JOREK and STARWALL for Non-linear Resistive-wall Simulations

The implementation of a resistive-wall extension to the non-linear MHD-code JOREK via a coupling to the vacuum-field code STARWALL is presented along with first applications and benchmark results. Also, non-linear saturation in the presence of a resistive wall is demonstrated. After completion of the ongoing verification process, this code extension will allow to perform non-linear simulations of MHD instabilities in the presence of three-dimensional resistive walls with holes for limited and X-point plasmas.Comment: Contribution for "Theory Of Fusion Plasmas, Joint Varenna - Lausanne International Workshop, Villa Monastero, Varenna, Italy (27.-31.8.2012)", accepted for publication in Journal of Physics Conference Serie