Astrobiologically Interesting Stars within 10 parsecs of the Sun

The existence of life based on carbon chemistry and water oceans relies upon planetary properties, chiefly climate stability, and stellar properties, such as mass, age, metallicity and Galactic orbits. The latter can be well constrained with present knowledge. We present a detailed, up-to-date compilation of the atmospheric parameters, chemical composition, multiplicity and degree of chromospheric activity for the astrobiologically interesting solar-type stars within 10 parsecs of the Sun. We determine their state of evolution, masses, ages and space velocities, and produce an optimized list of candidates that merit serious scientific consideration by the future space-based interferometry probes aimed at directly detecting Earth-sized extrasolar planets and seeking spectroscopic infrared biomarkers as evidence of photosynthetic life. The initially selected stars number 33 solar-type within the population of 182 stars (excluding late M-dwarfs) closer than 10 pc. A comprehensive and detailed data compilation for these objects is still essentially lacking: a considerable amount of recent data has so far gone unexplored in this context. We present 13 objects as the nearest "biostars", after eliminating multiple stars, young, chromospherically active, hard X-ray emitting stars, and low metallicity objects. Three of these "biostars", HD 1581, 109358 and 115617, closely reproduce most of the solar properties and are considered as premier targets. We show that approximately 7% of the nearby stars are optimally interesting targets for exobiology.Comment: 36 pages, recommended for publication in Astrobiolog

Discovery of the benchmark metal poor T8 dwarf BD+01 2920B

We have searched the WISE first data release for widely separated (<10,000AU) late T dwarf companions to Hipparcos and Gliese stars. We have discovered a new binary system containing a K-band suppressed T8p dwarf WISEP J1423+0116 and the mildly metal poor ([Fe/H]=-0.38+-0.06) primary BD+01 2920 (Hip 70319), a G1 dwarf at a distance of 17.2pc. This new benchmark has Teff=680+-55K and a mass of 20-50 Mjup. Its spectral properties are well modelled except for known discrepancies in the Y and K bands. Based on the well determined metallicity of its companion, the properties of BD+01 2920B imply that the currently known T dwarfs are dominated by young low-mass objects. We also present an accurate proper motion for the T8.5 dwarf WISEP J075003.84+272544.8.Comment: MNRAS, accepted 2012 January 1

Co-expression in Helicobacter pylori of cagA and non-opsonic neutrophil activation enhances the association with peptic ulcer disease

Aims—To investigate the association of cagA positivity and non-opsonic neutrophil activation capacity in wild-type Helicobacter pylori strains with peptic ulcer disease or chronic gastritis only. Methods—Helicobacter pylori were isolated from antral biopsies of 53 consecutive patients with chronic antral gastritis, of whom 24 had peptic ulcer disease endoscopically. The presence of cagA, a marker for the cag pathogenicity island, was determined by polymerase chain reaction with specific oligonucleotide primers, and non-opsonic neutrophil activation capacity by luminol enhanced chemiluminescence. Results—The cagA gene was present in 39 of 53 (73.6%) strains, 20 of which (83.3%) were from the 24 patients with peptic ulcer disease and 19 (65.5%) from the 29 patients with chronic gastritis only. Non-opsonic neutrophil activation was found in 29 (54.7%) strains, 16 of which (66.7%) were from patients with peptic ulcer disease, and 13 (44.8%) from those with chronic gastritis. Non-opsonic neutrophil activation was found more frequently in cagA(+) than cagA(-) strains (59% v 42.9%). Whereas four of the 14 cagA(-) strains and eight of the 24 non-opsonic neutrophil activation negative strains were from patients with peptic ulcer disease, only two of 24 (8.3%) peptic ulcer disease strains expressed neither cagA nor non-opsonic neutrophil activation. The cagA gene and non-opsonic neutrophil activation capacity were co-expressed in 14 of 24 (58.3%) strains from patients with peptic ulcer disease, and in nine of 29 (31%) strains from individuals with chronic gastritis. Conclusions—Positivity for cagA and non-opsonic neutrophil activation occur independently in wild-type H pylori strains. However, co-expression of the two markers enhanced the prediction of peptic ulcer disease. Key Words: Helicobacter pylori • neutrophil • cag