1,127 research outputs found

    Volcanology and petrogenesis of the Navajo Lake volcanic field

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    The Navajo Lake volcanic field is an ideal natural laboratory for volcanological and geochemical studies. This field extends from Navajo Lake, east of Cedar City, Utah to Panguitch Lake, Utah and lies in the Colorado Plateau and Basin and Range Transition Zone between the Hurricane and Sevier faults. The volcanic field is characterized by numerous basalt flows that erupted from more than 28 cinder cones. Many of the cones are aligned in a SE-NW direction. Three stages of basalt flows are recognized by mineralogy and morphology. Additionally, trachy-andesite occurs in the Panguitch Lake area. Many of the flows appear to be young because they are devoid of vegetation and have flow fronts 10 to 100 meters high. Flows erupted from the base and on the flanks of several cinder cones that are generally well covered by vegetation. In the Panguitch Lake area, the northernmost A\u27a flow is composed of a basal basalt flow and an upper trachy-andesite flow. These flows appear to have erupted from a common fissure system. The lava flow just north of Navajo Lake covers approximately 4 km2 and erupted from two vents on the west flank of a well-vegetated cone. Tertiary Brian Head and Claron formations and Isom formation pyroclastic flows underlie the volcanic field

    Detailed temporal structure of communication networks in groups of songbirds

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    This work was supported by EPSRC Early Career research fellowship EP/L020505/1

    Learning Timbre Analogies from Unlabelled Data by Multivariate Tree Regression

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    This is the Author's Original Manuscript of an article whose final and definitive form, the Version of Record, has been published in the Journal of New Music Research, November 2011, copyright Taylor & Francis. The published article is available online at http://www.tandfonline.com/10.1080/09298215.2011.596938

    Psychiatric Evaluation of the Agitated Patient: Consensus Statement of the American Association for Emergency Psychiatry Project BETA Psychiatric Evaluation Workgroup

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    It is difficult to fully assess an agitated patient, and the complete psychiatric evaluation usually cannot be completed until the patient is calm enough to participate in a psychiatric interview. Nonetheless, emergency clinicians must perform an initial mental status screening to begin this process as soon as the agitated patient presents to an emergency setting. For this reason, the psychiatric evaluation of the agitated patient can be thought of as a 2-step process. First, a brief evaluation must be aimed at determining the most likely cause of agitation, so as to guide preliminary interventions to calm the patient. Once the patient is calmed, more extensive psychiatric assessment can be completed. The goal of the emergency assessment of the psychiatric patient is not necessarily to obtain a definitive diagnosis. Rather, ascertaining a differential diagnosis, determining safety, and developing an appropriate treatment and disposition plan are the goals of the assessment. This article will summarize what components of the psychiatric assessment can and should be done at the time the agitated patient presents to the emergency setting. The complete psychiatric evaluation of the patient whose agitation has been treated successfully is beyond the scope of this article and Project BETA (Best practices in Evaluation and Treatment of Agitation), but will be outlined briefly to give the reader an understanding of what a full psychiatric assessment would entail. Other issues related to the assessment of the agitated patient in the emergency setting will also be discussed

    Reconstitution of Targeted Deadenylation by the Ccr4-Not Complex and the YTH Domain Protein Mmi1

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    SummaryCcr4-Not is a conserved protein complex that shortens the 3′ poly(A) tails of eukaryotic mRNAs to regulate transcript stability and translation into proteins. RNA-binding proteins are thought to facilitate recruitment of Ccr4-Not to certain mRNAs, but lack of an in-vitro-reconstituted system has slowed progress in understanding the mechanistic details of this specificity. Here, we generate a fully recombinant Ccr4-Not complex that removes poly(A) tails from RNA substrates. The intact complex is more active than the exonucleases alone and has an intrinsic preference for certain RNAs. The RNA-binding protein Mmi1 is highly abundant in preparations of native Ccr4-Not. We demonstrate a high-affinity interaction between recombinant Ccr4-Not and Mmi1. Using in vitro assays, we show that Mmi1 accelerates deadenylation of target RNAs. Together, our results support a model whereby both RNA-binding proteins and the sequence context of mRNAs influence deadenylation rate to regulate gene expression

    The association of wildfire smoke with respiratory and cardiovascular emergency department visits in Colorado in 2012: a case crossover study

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    In 2012, Colorado experienced one of its worst wildfire seasons of the past decade. The goal of this study was to investigate the relationship of local PM2.5 levels, modeled using the Weather Research and Forecasting Model with Chemistry, with emergency department visits and acute hospitalizations for respiratory and cardiovascular outcomes during the 2012 Colorado wildfires. Methods: Conditional logistic regression was used to assess the relationship between both continuous and categorical PM2.5 and emergency department visits during the wildfire period, from June 5th to July 6th 2012. Results: For respiratory outcomes, we observed positive relationships between lag 0 PM2.5 and asthma/wheeze (1 h max OR 1.01, 95 % CI (1.00, 1.01) per 10 mu g/m(3)24 h mean OR 1.04 95 % CI (1.02, 1.06) per 5 mu g/m(3)), and COPD (1 h max OR 1.01 95 % CI (1.00, 1.02) per 10 mu g/m(3)24 h mean OR 1.05 95 % CI (1.02, 1.08) per 5 mu g/m(3)). These associations were also positive for 2-day and 3-day moving average lag periods. When PM2.5 was modeled as a categorical variable, bronchitis also showed elevated effect estimates over the referent groups for lag 0 24 h average concentration. Cardiovascular results were consistent with no association. Conclusions: We observed positive associations between PM2.5 from wildfire and respiratory diseases, supporting evidence from previous research that wildfire PM2.5 is an important source for adverse respiratory health outcomes

    A Different Kind of Kid, A Different Kind of Teacher Education: Middle Grades Teachers Reflect on Their Preparation to Teach Young Adolescents

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    Good teaching at the middle grades comes out of a deep understanding of the unique cognitive, physical, social, emotional, and moral needs of young adolescents. Therefore specialized preparation is necessary to help teacher candidates understand how to operationalize the intersection of young adolescent development and the effective pedagogy that addresses their needs. This paper focuses on a qualitative study of experienced middle school teachers who graduated from a middle level preparation program or an elementary or secondary preparation program in terms of how well prepared they felt and feel to meet the widely varied needs of young adolescents. Confidence in preparation leads to high self-efficacy, which is important for perseverance and effectiveness. Graduates of a middle level preparation program reported higher levels of confidence in their preparation to teach young adolescents
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