Isolation and Characterization of New Leptospira Genotypes from Patients in Mayotte (Indian Ocean)

Leptospirosis has been recognized as an increasing public health problem affecting poor people from developing countries and tropical regions. However, the epidemiology of leptospirosis remains poorly understood in remote parts of the world. In this study of patients from the island of Mayotte, we isolated 22 strains from the blood of patients during the acute phase of illness. The pathogenic Leptospira strains were characterized by serology and various molecular typing methods. Based on serological data, serogroup Mini appears to be the dominant cause of leptospirosis in Mayotte. Further molecular characterization of these isolates allowed the identification of 10 pathogenic Leptospira genotypes that could correspond to previously unknown serovars. Further progress in our understanding of the epidemiology of Leptospira circulating genotypes in highly endemic regions should contribute to the development of novel strategies for the diagnosis and prevention of this neglected emerging disease

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

L'encadrement des frais d'analyse financière et de recherche

International audience(Arrêté du 3 juillet 2017 portant homologation de modifications du règlement général de l'Autorité des marchés financiers ; Financement de la recherche par les prestataires de services d'investissement dans le cadre de MIF 2, Guide AMF juill. 2017

Particularisme de l'obligation de restitution incombant au dépositaire

International audience(Com. 4 mai 2010, pourvoi n° 09-14.187, arrêt n° 500 FS-P+B, Société générale c/ Sté Day Trade Asset Management ; Com. 4 mai 2010, pourvoi n° 09-14.975, arrêt n° 497 FS-P+B, Sté RBC Dexia Investors services bank France c/ Sté Delta alternative management SAS, D. 2010. Actu. 1207, obs. A. Lienhard ; Com. 4 mai 2010, pourvoi n° 09-14.976, arrêt n° 498 FS-D, Sté RBC Dexia Investor services Bank France c/ Sté Laffitte capital management SAS

Recueil des informations relatives à la connaissance du client : l'Autorité de contrôle prudentiel et l'Autorité des marchés financiers renforcent leur vigilance au niveau de la commercialisation de services et de produits financiers

International audience(Position AMF n° 2013-02, Le recueil des informations relatives à la connaissance du client, 8 janvier 2013 ; Recommandation ACP n°2013-R-01, Le recueil des informations relatives à la connaissance du client dans le cadre du devoir de conseil en assurance vie, 8 janvier 2013

L'intermédiation en biens divers : nouvelles compétences de l'AMF pour protéger les épargnants

International audience(Instruction DOC-2017-06 : Procédure d'enregistrement et établissement d'un document d'information devant être déposé auprès de l'AMF par les intermédiaires en biens divers ; Arrêté du 27 avr. 2017 portant homologation de modifications du règlement général de l'Autorité des marchés financiers

Les investisseurs d'une SICAV ne peuvent s'immiscer dans les décisions de gestion de cette SICAV

International audienc

La directive OPCVM modifie la directive OPCVM IV pour ce qui est des fonctions de dépositaire, des politiques de rémunération et des sanctions

International audience(Directive 2014/91/UE du parlement européen et du conseil du 23 juillet 2014 modifiant la directive 2009/65/CE portant coordination des dispositions législatives, réglementaires et administratives concernant certains organismes de placement collectif en valeurs mobilières (OPCVM), pour ce qui est des fonctions de dépositaire, des politiques de rémunération et des sanctions