Occurrence and associative value of non-identifiable fingermarks

Fingermarks that have insufficient characteristics for identification often have discernible characteristics that could form the basis for lesser degrees of correspondence or probability of occurrence within a population. Currently, those latent prints that experts judge to be insufficient for identification are not used as associative evidence. How often do such prints occur and what is their potential value for association? The answers are important. We could be routinely setting aside a very important source of associative evidence, with high potential impact, in many cases; or such prints might be of very low utility, adding very little, or only very rarely contributing to cases in a meaningful way. The first step is to better understand the occurrence and range of associative value of these fingermarks. The project goal was to explore and test a theory that in large numbers of cases fingermarks of no value for identification purposes occur and are readily available, though not used, and yet have associative value that could provide useful information. Latent fingermarks were collected from nine state and local jurisdictions. Fingermarks included were those (1) collected in the course of investigations using existing jurisdictional procedures, (2) originally assessed by the laboratory as of no value for identification (NVID), (3) re-assessed by expert review as NVID, but with least three clear and reliable minutiae in relationship to one another, and (4) determined to show at least three auto-encoded minutiae. An expected associative value (ESLR) for each mark was measured, without reference to a putative source, based on modeling within-variability and between-variability of AFIS scores. This method incorporated (1) latest generation feature extraction, (2) a (minutiae-only) matcher, (3) a validated distortion model, and (4) NIST SD27 database calibration. Observed associative value distributions were determined for violent crimes, property crimes, and for existing objective measurements of latent print quality. 750 Non Identifiable Fingermarks (NIFMs) showed values of Log10 ESLR ranging from 1.05 to 10.88, with a mean value of 5.56 (s.d. 2.29), corresponding to an ESLR of approximately 380,000. It is clear that there are large numbers of cases where NIFMs occur that have high potential associative value as indicated by the ESLR. These NIFMs are readily available, but not used, yet have associative value that could provide useful information. These findings lead to the follow-on questions, “How useful would NIFM evidence be in actual practice?” and, “What developments or improvements are needed to maximize this contribution?

Dynamical Response of Nanomechanical Oscillators in Immiscible Viscous Fluid for in vitro Biomolecular Recognition

Dynamical response of nanomechanical cantilever structures immersed in a viscous fluid is important to in vitro single-molecule force spectroscopy, biomolecular recognition of disease-specific proteins, and the detection of microscopic dynamics of proteins. Here we study the stochastic response of biofunctionalized nanomechanical cantilevers beam in a viscous fluid. Using the fluctuation-dissipation theorem we derive an exact expression for the spectral density of the displacement and a linear approximation for the resonance frequency shift. We find that in a viscous solution the frequency shift of the nanoscale cantilever is determined by surface stress generated by biomolecular interaction with negligible contributions from mass loading.Comment: 4 pages, 2 figures, RevTex4. See http://nano.bu.edu/ for related paper

Pressure drag of bodies at Mach numbers up to 2.0

The drag of bodies has now assumed greater importance because, as shown in NACA RM L53I15a, 1953 and NACA RM A53H18a, 1953, the transonic drag rise of an airplane can be the same as its equivalent body. Obviously, the airplane designer would like his airplane to have a low-drag equivalent body. This paper shows some of the factors which minimize the drag of bodies at transonic and supersonic speeds and shows some of the penalties caused by deviating from low-drag body shapes. Drag reductions can be obtained in two ways, first, through increasing the body fineness ratio, and second, through better shaping of the body profile at a given fineness ratio. The effects of fineness ratio are discussed first and then, more completely, detail-shape effects

Bio-physical closure criteria without reference sites: Realistic targets in modified rivers

The use of reference sites for establishing closure criteria in areas disturbed by mining activities is common practice. ‘Reference’ sites are those considered to be largely unimpacted by anthropogenic activity (retaining desirable natural characteristics), and occurring near disturbed sites. Sites are considered rehabilitated when their biophysical condition approximates that of the reference site. However, this approach often creates impossible or unrealistic targets for miners seeking to close rehabilitated lands. For example, reference sites are often limited in availability (or non-existent) due to impacts by other land uses. Further, any available reference sites might not be realistic matches for the rehabilitated sites – in many rivers (for example) it is questionable whether sites which superficially appear similar are actually ecologically similar. We propose a more achievable approach to mine closure by comparing the bio-physical characteristics of rehabilitated sites to overall ecosystem variability, rather than specific target reference sites. Using multivariate ordination - a classic data clustering technique in ecology - as an applied management tool allows managers to measure how different their rehabilitated sites are from co-occurring sites, and how the rehabilitated sites are tracking over time. Our approach also identifies the key biological, physical, and chemical parameters that potentially differentiate a rehabilitated site and, therefore, the necessary actions to bring a rehabilitation site within range of normal river variability. Further, this conceptual paper introduces two unique case studies used to develop the model, involving microbes as indicators of rehabilitation progress and mine water impact in Australian rivers. The challenges and benefits associated with implementation of this approach from the practitioners’ perspectives are discussed. The outcome of this new approach to closure will allow miners to create realistic and definable targets for relinquishing rehabilitation land in already modified landscapes, potentially simplifying closure and project approvals

Royal academy of medicine in Ireland

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Disentangling the multigenic and pleiotropic nature of molecular function

Background: Biological processes at the molecular level are usually represented by molecular interaction networks. Function is organised and modularity identified based on network topology, however, this approach often fails to account for the dynamic and multifunctional nature of molecular components. For example, a molecule engaging in spatially or temporally independent functions may be inappropriately clustered into a single functional module. To capture biologically meaningful sets of interacting molecules, we use experimentally defined pathways as spatial/temporal units of molecular activity. Results: We defined functional profiles of Saccharomyces cerevisiae based on a minimal set of Gene Ontology terms sufficient to represent each pathway's genes. The Gene Ontology terms were used to annotate 271 pathways, accounting for pathway multi-functionality and gene pleiotropy. Pathways were then arranged into a network, linked by shared functionality. Of the genes in our data set, 44% appeared in multiple pathways performing a diverse set of functions. Linking pathways by overlapping functionality revealed a modular network with energy metabolism forming a sparse centre, surrounded by several denser clusters comprised of regulatory and metabolic pathways. Signalling pathways formed a relatively discrete cluster connected to the centre of the network. Genetic interactions were enriched within the clusters of pathways by a factor of 5.5, confirming the organisation of our pathway network is biologically significant. Conclusions: Our representation of molecular function according to pathway relationships enables analysis of gene/protein activity in the context of specific functional roles, as an alternative to typical molecule-centric graph-based methods. The pathway network demonstrates the cooperation of multiple pathways to perform biological processes and organises pathways into functionally related clusters with interdependent outcomes

Standard and derived Planck quantities: selected analysis and derivations

We provide an overview of the fundamental units of physical quantities determined naturally by the values of fundamental constants of nature. We discuss a comparison between the 'Planck units', now widely used in theoretical physics and the pre-quantum 'Stoney units' in which, instead of the Planck constant, the charge of the electron is used with very similar quantitative results. We discuss some of the physical motivation for these special units, attributed much after they were introduced, and also put forth a summary of the arguments supporting various cases for making specific physical interpretations of the meanings of some of these units. The new aspects we discuss are a possible physical basis for the Stoney units, their link to the Planck units, and also the importance of Planck units for thermodynamical quantities in the context of quantum gravity.Comment: 22 pages, 1 tabl

Variable Curvature Slab Molecular Dynamics as a Method to Determine Surface Stress

A thin plate or slab, prepared so that opposite faces have different surface stresses, will bend as a result of the stress difference. We have developed a classical molecular dynamics (MD) formulation where (similar in spirit to constant-pressure MD) the curvature of the slab enters as an additional dynamical degree of freedom. The equations of motion of the atoms have been modified according to a variable metric, and an additional equation of motion for the curvature is introduced. We demonstrate the method to Au surfaces, both clean and covered with Pb adsorbates, using many-body glue potentials. Applications to stepped surfaces, deconstruction and other surface phenomena are under study.Comment: 16 pages, 8 figures, REVTeX, submitted to Physical Review

Women We Loved: Paradoxes of public and private in the biographical television drama

Broadcast to critical acclaim and relatively large audiences for its niche channel, the Women We Loved season consisted of biographical dramatisations of three prominent female figures of 20th-century British culture. These dramas shared in common narratives that centre on the two aspects of ‘the public’ and ‘the private’: the tension between public career and personal life and the discrepancy between celebrity persona and private individual. Combining theoretical insights from feminist studies of biography with close textual analysis, this article analyses how performance, aesthetics and narrative express the ambivalent placement of their protagonists between public and private spheres

Trialogue on the number of fundamental constants

This paper consists of three separate articles on the number of fundamental dimensionful constants in physics. We started our debate in summer 1992 on the terrace of the famous CERN cafeteria. In the summer of 2001 we returned to the subject to find that our views still diverged and decided to explain our current positions. LBO develops the traditional approach with three constants, GV argues in favor of at most two (within superstring theory), while MJD advocates zero.Comment: Version appearing in JHEP; 31 pages late