On connectivity in the central nervous systeem : a magnetic resonance imaging study

Brain function has long been the realm of philosophy, psychology and psychiatry and since the mid 1800s, of histopathology. Through the advent of magnetic imaging in the end of the last century, an in vivo visualization of the human brain became available. This thesis describes the development of two unique techniques, imaging of diffusion of water protons and manganese enhanced imaging, that both allow for the depiction of white matter tracts. The reported studies show, that these techniques can be used for a three-dimensional depiction of fiber bundles and that quantitative measures reflecting fiber integrity and neuronal function can be extracted from such data. In clinical applications, the potential use of the developed methods is illustrated in human gliomas, as measure for fiber infiltration, and in spinal cord injury, to monitor potential neuroprotective and __regenerative medication.UBL - phd migration 201

Polynomials Associated with Equilibria of Affine Toda-Sutherland Systems

An affine Toda-Sutherland system is a quasi-exactly solvable multi-particle dynamics based on an affine simple root system. It is a `cross' between two well-known integrable multi-particle dynamics, an affine Toda molecule and a Sutherland system. Polynomials describing the equilibrium positions of affine Toda-Sutherland systems are determined for all affine simple root systems.Comment: 9 page

Spectra and Symmetry in Nuclear Pairing

We apply the algebraic Bethe ansatz technique to the nuclear pairing problem with orbit dependent coupling constants and degenerate single particle energy levels. We find the exact energies and eigenstates. We show that for a given shell, there are degeneracies between the states corresponding to less and more than half full shell. We also provide a technique to solve the equations of Bethe ansatz.Comment: 15 pages of REVTEX with 2 eps figure

The impact of Stieltjes' work on continued fractions and orthogonal polynomials

Stieltjes' work on continued fractions and the orthogonal polynomials related to continued fraction expansions is summarized and an attempt is made to describe the influence of Stieltjes' ideas and work in research done after his death, with an emphasis on the theory of orthogonal polynomials

Solution of a Generalized Stieltjes Problem

We present the exact solution for a set of nonlinear algebraic equations $\frac{1}{z_l}= \pi d + \frac{2 d}{n} \sum_{m \neq l} \frac{1}{z_l-z_m}$. These were encountered by us in a recent study of the low energy spectrum of the Heisenberg ferromagnetic chain \cite{dhar}. These equations are low $d$ (density) ``degenerations'' of more complicated transcendental equation of Bethe's Ansatz for a ferromagnet, but are interesting in themselves. They generalize, through a single parameter, the equations of Stieltjes, $x_l = \sum_{m \neq l} 1/(x_l-x_m)$, familiar from Random Matrix theory. It is shown that the solutions of these set of equations is given by the zeros of generalized associated Laguerre polynomials. These zeros are interesting, since they provide one of the few known cases where the location is along a nontrivial curve in the complex plane that is determined in this work. Using a ``Green's function'' and a saddle point technique we determine the asymptotic distribution of zeros.Comment: 19 pages, 4 figure

Richardson-Gaudin integrability in the contraction limit of the quasispin

Background: The reduced, level-independent, Bardeen-Cooper-Schrieffer Hamiltonian is exactly diagonalizable by means of a Bethe Ansatz wavefunction, provided the free variables in the Ansatz are the solutions of the set of Richardson-Gaudin equations. On the one side, the Bethe Ansatz is a simple product state of generalised pair operators. On the other hand, the Richardson-Gaudin equations are strongly coupled in a non-linear way, making them prone to singularities. Unfortunately, it is non-trivial to give a clear physical interpretation to the Richardson-Gaudin variables because no physical operator is directly related to the individual variables. Purpose: The purpose of this paper is to shed more light on the critical behavior of the Richardson-Gaudin equations, and how this is related to the product wave structure of the Bethe Ansatz. Method: A pseudo-deformation of the quasi-spin algebra is introduced, leading towards a Heisenberg-Weyl algebra in the contraction limit of the deformation parameter. This enables an adiabatic connection of the exact Bethe Ansatz eigenstates with pure bosonic multiphonon states. The physical interpretation of this approach is an adiabatic suppression of the Pauli exclusion principle. Results: The method is applied to a so-called "picket-fence" model for the BCS Hamiltonian, displaying a typical critical behavior in the Richardson-Gaudin variables. It was observed that the associated bosonic multiphonon states change collective nature at the critical interaction strengths of the Richardson-Gaudin equations. Conclusions: The Pauli exclusion principle is the main responsible for the critical behavior of the Richardson-Gaudin equations, which can be suppressed by means of a pseudo deformation of the quasispin algebra.Comment: PACS 02.30.Ik, 21.10.Re, 21.60.Ce, 74.20.F

A generalization of the Heine--Stieltjes theorem

We extend the Heine-Stieltjes Theorem to concern all (non-degenerate) differential operators preserving the property of having only real zeros. This solves a conjecture of B. Shapiro. The new methods developed are used to describe intricate interlacing relations between the zeros of different pairs of solutions. This extends recent results of Bourget, McMillen and Vargas for the Heun equation and answers their question on how to generalize their results to higher degrees. Many of the results are new even for the classical case.Comment: 12 pages, typos corrected and refined the interlacing theorem

Approximate volume and integration for basic semi-algebraic sets

Given a basic compact semi-algebraic set \K\subset\R^n, we introduce a methodology that generates a sequence converging to the volume of \K. This sequence is obtained from optimal values of a hierarchy of either semidefinite or linear programs. Not only the volume but also every finite vector of moments of the probability measure that is uniformly distributed on \K can be approximated as closely as desired, and so permits to approximate the integral on \K of any given polynomial; extension to integration against some weight functions is also provided. Finally, some numerical issues associated with the algorithms involved are briefly discussed

Determination of the Defining Boundary in Nuclear Magnetic Resonance Diffusion Experiments

While nuclear magnetic resonance diffusion experiments are widely used to resolve structures confining the diffusion process, it has been elusive whether they can exactly reveal these structures. This question is closely related to X-ray scattering and to Kac's "hear the drum" problem. Although the shape of the drum is not "hearable", we show that the confining boundary of closed pores can indeed be detected using modified Stejskal-Tanner magnetic field gradients that preserve the phase information and enable imaging of the average pore in a porous medium with a largely increased signal-to-noise ratio.Comment: 13 pages, 2 figure

Continued fraction solution of Krein's inverse problem

The spectral data of a vibrating string are encoded in its so-called characteristic function. We consider the problem of recovering the distribution of mass along the string from its characteristic function. It is well-known that Stieltjes' continued fraction provides a solution of this inverse problem in the particular case where the distribution of mass is purely discrete. We show how to adapt Stieltjes' method to solve the inverse problem for a related class of strings. An application to the excursion theory of diffusion processes is presented.Comment: 18 pages, 2 figure