144 research outputs found

    From Ultimatum to Nash Bargaining: Theory and Experimental Evidence

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    commitment;imperfect observability;ultimatum bargaining games;Nash bargaining game;experiments

    Control of Diffuse Vacuum Arc Using Axial Magnetic Fields in Commercial High Voltage Switchgear

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    During the development of a commercial vacuum interrupter for application in HV (high voltage) switchgear at a rated voltage of 145kV, we investigated the behavior of vacuum arcs controlled by axial magnetic fields (AMF). AMF arc control is already extensively used in medium voltage (1-52kV) applications, the key difference is the 2-3 times larger contact gap and the corresponding reduction of the AMF strength for HV applications. We conducted several stress tests with short circuit currents up to 40kA, thus not only testing the interrupting capability, but also the electrical endurance of such a contact system. We also investigated the dielectric behavior of the vacuum interrupter by testing the capacitive switching duty. Overall, the contacts were used in about 40 operations at high currents. Despite this large number of operations, they showed a minimal amount of contact erosion and damage and demonstrated behavior very similar to the extensive experience with MV vacuum interrupters. In line with simulation results, we conclude that even at high contact gaps and currents, a diffuse vacuum arc was maintained which distributed the arc energy evenly over the contacts

    The Potential Impact of Heparanase Activity and Endothelial Damage in COVID-19 Disease

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    SARS-CoV-2 was first detected in 2019 in Wuhan, China. It has been found to be the most pathogenic virus among coronaviruses and is associated with endothelial damage resulting in respiratory failure. Determine whether heparanase and heparan sulfate fragments, biomarkers of endothelial function, can assist in the risk stratification and clinical management of critically ill COVID-19 patients admitted to the intensive care unit. We investigated 53 critically ill patients with severe COVID-19 admitted between March and April 2020 to the University Hospital RWTH Aachen. Heparanase activity and serum levels of both heparanase and heparan sulfate were measured on day one (day of diagnosis) and day three in patients with COVID-19. The patients were classified into four groups according to the severity of ARDS. When compared to baseline data (day one), heparanase activity increased and the heparan sulfate serum levels decreased with increasing severity of ARDS. The heparanase activity significantly correlated with the lactate concentration on day one (r = 0.34, p = 0.024) and on day three (r = 0.43, p = 0.006). Heparanase activity and heparan sulfate levels correlate with COVID-19 disease severity and outcome. Both biomarkers might be helpful in predicting clinical course and outcomes in COVID-19 patients

    An advanced risk analysis approach for container port safety evaluation

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    Risk analysis in seaports plays an increasingly important role in ensuring port operation reliability, maritime transportation safety and supply chain distribution resilience. However, the task is not straightforward given the challenges, including that port safety is affected by multiple factors related to design, installation, operation and maintenance and that traditional risk assessment methods such as quantitative risk analysis cannot sufficiently address uncertainty in failure data. This paper develops an advanced Failure Mode and Effects Analysis (FMEA) approach through incorporating Fuzzy Rule-Based Bayesian Networks (FRBN) to evaluate the criticality of the hazardous events (HEs) in a container terminal. The rational use of the Degrees of Belief (DoB) in a fuzzy rule base (FRB) facilitates the implementation of the new method in Container Terminal Risk Evaluation (CTRE) in practice. Compared to conventional FMEA methods, the new approach integrates FRB and BN in a complementary manner, in which the former provides a realistic and flexible way to describe input failure information while the latter allows easy updating of risk estimation results and facilitates real-time safety evaluation and dynamic risk-based decision support in container terminals. The proposed approach can also be tailored for wider application in other engineering and management systems, especially when instant risk ranking is required by the stakeholders to measure, predict and improve their system safety and reliability performance

    Sequestration of defenses against predators drives specialized host plant associations in preadapted milkweed bugs (Heteroptera: Lygaeinae)

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    AbstractHost plant specialization across herbivorous insects varies dramatically, but while the molecular mechanisms of host plant adaptations are increasingly known, we often lack a comprehensive understanding of the selective forces that favor specialization. The milkweed bugs (Heteroptera: Lygaeinae) are ancestrally associated with plants of the Apocynaceae from which they commonly sequester cardiac glycosides for defense, facilitated by resistant NaNa+/K+-ATPases and adaptations for transport, storage, and discharge of toxins. Here, we show that three Lygaeinae species independently colonized four novel nonapocynaceous hosts that convergently produce cardiac glycosides. A fourth species shifted to a new source of toxins by tolerating and sequestering alkaloids from meadow saffron (Colchicum autumnale, Colchicaceae). Across three milkweed bug species tested, feeding on seeds containing toxins did not improve growth or speed of development and even impaired growth and development in two species, but sequestration mediated protection of milkweed bugs against two natural predators: lacewing larvae and passerine birds. We conclude that physiological preadaptations and convergent phytochemistry facilitated novel specialized host associations. Since toxic seeds did not improve growth but either impaired growth or, at most, had neutral effects, selection by predators on sequestration of defenses, rather than the exploitation of additional profitable dietary resources, can lead to obligatory specialized host associations in otherwise generalist insects
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