1,580 research outputs found
Breach of confidentiality and the duty to warn in medical law: Examples from clinical psychiatry
This article addresses various factors involved in the tension that may arise between breach of confidentiality on the one hand, and dereliction of the duty to warn, on the other, in the context of medical law. Per illustration, examples from clinical psychiatric practice, in which the sharing of personal information is especially relevant, are featured. In sum, a practitioner must be reasonable in negotiating the proverbial tightrope: if he or she reveals too much, liability can arise, and, if he or she reveals too little, liability can arise. In medical law, the standard of reasonableness is measured with reference to âthe reasonable practitionerâ. Weighing up various factors (discussed herein), the reasonable practitioner takes confidentiality as the point of departure; only if there is a compelling reason to override confidentiality, will it afford legal justification to the practitioner
Carcinoid heart disease: Two clinical cases and a review
We present two cases of metastatic carcinoid tumours, complicated by carcinoid syndrome and by cardiac valve involvement, a well-known, but infrequent, complication. Carcinoid tumours are generally more indolent than other cancers and may have a long asymptomatic phase. The symptoms of carcinoid syndrome generally manifest only once metastases to the liver have occurred. Cardiac involvement occurs in up to 50% of patients, and heralds a poor prognosis. However, a multidisciplinary team approach has improved the prognosis and quality of life for patients with carcinoid heart disease. Therapy includes somatostatin analogues and treatment for heart failure, removal of primary or metastatic tumour deposits, valve replacement in the presence of valvular involvement, and radioisotopes therapy
Improving cost-effectiveness of hypertension management at a community health centre
Objectives. To describe the pattern of prescribing for hypertension at a community health centre (CHC) and to evaluate the impact of introducing treatment guidelines and restricting availability of less cost-effective antihypertensive drugs on prescribing patterns, costs of drug treatment and blood pressure (BP) control.Design. Before/after intervention study.Setting. Medium-sized CHC in the Cape Flats area of Cape Town.Subjects. 1 084 hypertensive patients attending the CHC, who had at least two prescriptions for antihypertensive drugs during a 1-year period starting on 1 January 1992. Interventions. 1. Implementation of stepped-care guidelines for hypertension, specifying treatment with more cost-effective drugs and minimising drug treatment. 2. Reducing availability for routine prescribing by CHC doctors of 10 less cost-effective antihypertensive drugs or drug combinations.Outcome measures. 1. Mean number of drugs prescribed per patient. 2. Proportion of prescriptions for: each major class of antihypertensive drug; restricted availability and freely prescribable drugs; and more and less cost-effective drugs. 3. Mean monthly cost of drugs prescribed per patient. 4. Mean blood pressure and proportion of BP readings controlled (<160/95 mmHg) or uncontrolled (â„160/95 mmHg).Results. A mean of 1.7 active drugs was prescribed per patient per visit. The most frequently prescribed drugs were thiazide-like diuretics (44.8%), centrally acting agents (28.4%) and b-blockers (13.2%). Mean monthly drug costs per patient decreased significantly by R1.99 (24.2%) from R8.24 to R6.25 between the first and last prescription for each patient (exclusive of any reduction due to withdrawal of treatment). This was attributable to reduced prescribing of more expensive drugs withdrawn from routine use and a 51.1% increase in prescribing of the most cost-effective drugs. The overall annual cost-saving of the changes in prescribing for this CHC are estimated at R75 150. Blood pressure control did not change significantly.Conclusion. The pattern of changes in prescribing and drug costs was consistent with a causal effect of the interventions. The study demonstrates the potential forimproving cost-effectiveness of hypertension care in primary care in South Africa and the potential for research in this setting
Hypertension care at a Cape Town community health centre
Objectives. To describe the demographic profile of hypertensive patients and the quality of care for hypertension at a Cape Town community health centre (CHC).Design. Prospective, descriptive study.Setting and subjects. Medium-sized CHC, attended by 1098 hypertensive patients during a 1-year period from 1 January 1992.Outcome measures. Default rate - proportion of due visits not attended. Loss to follow-up - proportion of patients persistently defaulting or not responding to recall. Frequency of blood pressure measurement - per 12 due visits. Compliance - proportion of patients collecting â„ 75% of antihypertensive drugs. Blood pressure control - mean blood pressure of aggregated readings; and proportion controlled (<160/95 mmHg) on the basis of all blood pressure readings and mean blood pressures of individual patients with two or more readings during the study period.Results. More than half (51.6%) of the hypertensive patients were aged â„ 65 years; 81.7% were female. The default rate was between 11.9% and 19.4%. Compliance was high (76.9%). Loss to follow-up was 8.1 %. Blood pressure was recorded a mean of 4.0 times per 12 due visits. There were no significant gender differences with regard to these measures. Mean blood pressure was 158.3/89.6 mmHg. Over half (56.7%) of all individual readings over the year were uncontrolled and 51.4% of patients were found to be uncontrolled when categorised by their mean blood pressure. Control was significantly poorer among women â„ 65 years.Conclusion. We found better compliance, more frequent blood pressure measurement, and lower defaulting and loss to follow-up compared with previous South African studies in similar settings. Despite this, blood pressure control was mediocre. Possible explanations for this are discussed. The low proportion of male hypertensives attending the CHC suggests that the accessibility or acceptability of care is poor for this group. The study illustrates the potential for research in this setting and for the use of computers to monitor the quality of primary care.
Excitation functions of (nat)Zr+p nuclear processes up to 70 MeV: New measurements and compilation
'A Monstrous Failure of Justice'?:Guantanamo Bay and National Security Challenges to Fundamental Human Rights
No evidence of an 11.16 MeV 2+ state in 12C
An experiment using the 11B(3He,d)12C reaction was performed at iThemba LABS
at an incident energy of 44 MeV and analyzed with a high energy-resolution
magnetic spectrometer, to re-investigate states in 12C published in 1971. The
original investigation reported the existence of an 11.16 MeV state in 12C that
displays a 2+ nature. In the present experiment data were acquired at
laboratory angles of 25-, 30- and 35- degrees, to be as close to the c.m.
angles of the original measurements where the clearest signature of such a
state was observed. These new low background measurements revealed no evidence
of the previously reported state at 11.16 MeV in 12C
Urban water balance 1 Model for daily totals.
The water balance provides a framework through which to study the interactions between the elements of the hydrologic cycle. This paper presents a simple model for evaluating the components of the urban water balance based on standard climate data and easily obtained parameters to describe the site. The time scale can be varied from 1 day to at least 1 year depending on the availability of appropriate input data and the form of the evapotranspiration submodel chosen. The evapotranspiration model proposed is of the combination type with modifications to allow for application to the suburban environment. An important methodological concept throughout the model is the recognition that a suburban area can be subdivided into three discrete surface types for hydroclimate purposes (impervious, pervious unirrigated, and pervious irrigated). Presented in this paper is an outline of the model, sensitivity analyses, and information for its implementation
Multimorbidity, control and treatment of noncommunicable diseases among primary healthcare attenders in the Western Cape, South Africa
Background. South Africa (SA) is facing a heavy burden of non-communicable diseases (NCDs). Few studies address multimorbidity, control and treatment of NCDs in patients attending primary healthcare (PHC) clinics. Objectives. To describe multimorbidity, related risk factors, disease severity and treatment status of patients with four important NCDs attending public sector PHC clinics in two districts in SA. Methods. A cross-sectional sample of patients completed baseline data collection for a randomised controlled trial of a health systems intervention. The study population comprised adults attending PHC clinics in the Eden and Overberg districts of the Western Cape in 2011. Four subgroups of patients were identified: hypertension, diabetes, chronic respiratory disease and depression. A total of 4 393 participants enrolled from 38 clinics completed a baseline structured questionnaire and had measurements taken. Prescription data were recorded. Results. Of participants with hypertension, diabetes, respiratory disease and depression, 80%, 92%, 88% and 80%, respectively, had at least one of the other three conditions. There were low levels of control and treatment: 59% of participants with hypertension had a blood pressure â„140/90 mmHg, the mean haemoglobin A1c (HbA1c) value in participants with diabetes was 9%, 12% of participants in the depression group were prescribed an antidepressant at a therapeutic dose, and 48% of respiratory participants were prescribed a b2-agonist and 34% an inhaled corticosteroid. Conclusion. Considerable multimorbidity and unmet treatment needs exist among patients with NCDs attending public sector PHC clinics. Improved strategies are required for diagnosing and managing NCDs in this sector
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