243 research outputs found
Manue Application Effects on Residue, Odor, and Placement
Field experiments in no-till soybean and corn residue were conducted to evaluate six liquid swine manure application methods. The methods were injection with a conventional knife or sweep, incorporation with tandem disk after broadcast application, broadcast application, injection with a narrow-profile knife, and surface application behind row cleaners. The row cleaner and all injection treatments used finger-closing wheels. Air samples over the soil surface were obtained during and after application and residue cover was measured. Odor level was measured by the amount of air dilutions to reach odor threshold. Placement of material into the soil was evaluated with dye. Incorporation techniques typically reduced odor level by a factor of four to ten as compared to a broadcast application. Differences among application methods were more pronounced in soybean residue. Application by the narrow-profile knife, row cleaner, and to a lesser extent the conventional knife maintained soybean residue cover better than other incorporation methods and limited odor similar to other incorporation methods. Differences among methods in odor level and residue cover were less in corn. The knife and row cleaner methods maintained greater corn residue cover than other incorporation techniques, but were more variable in odor level. For both crops, broadcast application maintained the greatest residue cover, but had the highest odor level. Material was incorporated five to seven inches deep by the knife, sweep, and narrow knife; two to three inches deep by the tandem disk and row cleaner; and at the surface by broadcast application
Diabetes Medication Assistance Service: The pharmacist's role in supporting patient self-management of type 2 diabetes (T2DM) in Australia
Objective. To evaluate the capacity and effectiveness of trained community pharmacists in delivering the Diabetes Medication Assistance Service (DMAS) via (1) number and types of self-management support interventions (SMSIs); (2) number of goals set and attained by patients and (3) patient outcomes (glycaemic control, medication adherence and satisfaction). Methods. Pharmacists (n = 109) from 90 community pharmacies in Australia were trained and credentialed to deliver the DMAS. The training focused on developing pharmacists’ knowledge and skills in supporting patients’ diabetes self-management. Results. A total of 387 patients completed the trial. The mean number of SMSIs per patient was 35 (SD ±31) and the majority (87%) had at least one documented goal that was fully or partially attained. There were significant health benefits for patients including improved glycaemic control and a reduced risk of non-adherence to medications. Over 90% of DMAS patients reported improvements in their knowledge about diabetes self-management.Conclusion. The DMAS provides self management support in the community pharmacy for people with T2DM which may result in improved clinical outcomes. Practice implication. Given appropriate training in diabetes care and behavior change strategies, community pharmacists can offer programs which provide self-management support to their patients with T2DM and improve their health outcomes
The pulsating hot subdwarf Balloon 090100001: results of the 2005 multisite campaign
We present the results of a multisite photometric campaign on the pulsating
sdB star Balloon 090100001. The star is one of the two known hybrid hot
subdwarfs with both long- and short-period oscillations. The campaign involved
eight telescopes with three obtaining UBVR data, four B-band data, and one
Stromgren uvby photometry. The campaign covered 48 nights, providing a temporal
resolution of 0.36microHz with a detection threshold of about 0.2mmag in
B-filter data.
Balloon 090100001 has the richest pulsation spectrum of any known pulsating
subdwarf B star and our analysis detected 114 frequencies including 97
independent and 17 combination ones. The strongest mode (f_1) in the 2.8mHz
region is most likely radial while the remaining ones in this region form two
nearly symmetric multiplets: a triplet and quintuplet, attributed to
rotationally split \ell=1 and 2 modes, respectively. We find clear increases of
splitting in both multiplets between the 2004 and 2005 observing campaigns,
amounting to 15% on average. The observed splittings imply that the rotational
rate in Bal09 depends on stellar latitude and is the fastest on the equator. We
use a small grid of models to constrain the main mode (f_1), which most likely
represents the radial fundamental pulsation. The groups of p-mode frequencies
appear to lie in the vicinity of consecutive radial overtones, up to the third
one. Despite the large number of g-mode frequencies observed, we failed to
identify them, most likely because of the disruption of asymptotic behaviour by
mode trapping. The observed frequencies were not, however, fully exploited in
terms of seismic analysis which should be done in the future with a larger grid
of reliable evolutionary models of hot subdwarfs.Comment: accepted for publication in MNRA
The inflammatory microenvironment in colorectal neoplasia
Peer reviewedPublisher PD
Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown
Epithelial cells that line the gut secrete complex glycoproteins that form a mucus layer to protect the gut wall from enteric pathogens. Here, the authors provide a comprehensive characterisation of endo-acting glycoside hydrolases expressed by mucin-degrading members of the microbiome that are able to cleave the O-glycan chains of a range of different animal and human mucins
Implementation of neuro-oncology service reconfiguration in accordance with NICE guidance provides enhanced clinical care for patients with glioblastoma multiforme.
BACKGROUND: Brain tumours account for <2% of all primary neoplasms but are responsible for 7% of the years of life lost from cancer before age 70 years. The latest survival trends for patients with CNS malignancies have remained largely static. The objective of this study was to evaluate the change in practice as a result of implementing the Improving Outcomes Guidance from the UK National Institute for Health and Clinical Excellence (NICE). METHODS: Patients were identified from the local cancer registry and hospital databases. We compared time from diagnosis to treatment, proportion of patients discussed at multidisciplinary team (MDT) meetings, treatment received, length of inpatient stay and survival. Inpatient and imaging costs were also estimated. RESULTS: Service reconfiguration and implementation of NICE guidance resulted in significantly more patients being discussed by the MDT--increased from 66 to 87%, reduced emergency admission in favour of elective surgery, reduced median hospital stay from 8 to 4.5 days, increased use of post-operative MRI from 17 to 91% facilitating early discharge and treatment planning, and reduced cost of inpatient stay from £2096 in 2006 to £1316 in 2009. Patients treated with optimal surgery followed by radiotherapy with concomitant and adjuvant temozolomide achieved outcomes comparable to those reported in clinical trials: median overall survival 18 months (2-year survival 35%). CONCLUSIONS: Advancing the management of neuro-oncology patients by moving from an emergency-based system of patient referral and management to a more planned elective outpatient-based pattern of care improves patient experience and has the potential to deliver better outcomes and research opportunities
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Spring 1959
Seed testing - A Service for You by Miss Jessie L. Anderson (page 1) Increased Interest in Two-Year Turf Course by Fred P. Jeffrey - Director of Stockbridge (4) From the Editor (4) Message From Winter School President of 1959 (5) Turf club News (6) Number One Graduate (8) Liquid Fertilization by A.B. Longo (9) Public School Grounds by James Woodhouse (12) Comments on the 1959 Winter School (14) Picture - Stockbridge Turf Majors (16) Picture - Honorary Members of Turf Management Club (17) Letter on Chemical Compatibility (18) The Most Outstanding Turf Senior for 1958 (19) What it Means to be a Turf Manager by R. Russell (20) 10 Steps to a Better Lawn by P. Pedrazzi (24) A Scene to Remember (25) I switched from Hots to Cools by J. Spodnik (26) Why Attend Turfgrass Conferences (27) Picture - Winter School for Turf Managers - 1959 (29) Picture - University of Masssachusetts Annual Turfgrass Conference (30) Organic Fertilizers by O.J. Noer (A-1) Inorganic Fertilizers by Charles Winchell (A-1) Urea Formaldehyde by G.F. Stewart (A-2) Phosphorus and Potash Fertilization by Raph Donaldson (A-3) Questions on Fertilization to the Panel (A-4) Cemetery Maintenance by S.E. Robbins (A-6) Lime by Anson Brewer (A-6) Limited Budgets by R.W. Sharkey (A-7) Fertilization of Park Turf by E.J. Pyle (A-7) Disease and Insect Control by Orlando Capizzi (A-8) Cost of Establishing Turf by Victor Taricano (A-9) Question and Answers (A-10) Control of Pests of Ornamentals and Turf Occuring on Golf Courses by John C. Schread (A-12) Behind the Scenes in Soil Testing and What it Means to You Bertram Gersten and Wm. G. Colby (A-19) Lessons Learned from the 1958 Season as Applied to Golf Course Maintenance by A.M. Radko (A-21) The Outlook in Chemical Weed Control on Fine Turf by John Gallagher (A-24) New Developments in Turfgrass Disease Diagnosis and Control by Frank Howard (A-26
Geckos decouple fore- and hind limb kinematics in response to changes in incline
This work is supported by an NSF grant (NSF IOS-1147043) to TE
Structure of Chimpanzee Gut Microbiomes across Tropical Africa
Understanding variation in host-associated microbial communities is important given the relevance of microbiomes to host physiology and health. Using 560 fecal samples collected from wild chimpanzees (Pan troglodytes) across their range, we assessed how geography, genetics, climate, vegetation, and diet relate to gut microbial community structure (prokaryotes, eukaryotic parasites) at multiple spatial scales. We observed a high degree of regional specificity in the microbiome composition, which was associated with host genetics, available plant foods, and potentially with cultural differences in tool use, which affect diet. Genetic differences drove community composition at large scales, while vegetation and potentially tool use drove within-region differences, likely due to their influence on diet. Unlike industrialized human populations in the United States, where regional differences in the gut microbiome are undetectable, chimpanzee gut microbiomes are far more variable across space, suggesting that technological developments have decoupled humans from their local environments, obscuring regional differences that could have been important during human evolution. IMPORTANCE Gut microbial communities are drivers of primate physiology and health, but the factors that influence the gut microbiome in wild primate populations remain largely undetermined. We report data from a continent-wide survey of wild chimpanzee gut microbiota and highlight the effects of genetics, vegetation, and potentially even tool use at different spatial scales on the chimpanzee gut microbiome, including bacteria, archaea, and eukaryotic parasites. Microbial community dissimilarity was strongly correlated with chimpanzee population genetic dissimilarity, and vegetation composition and consumption of algae, honey, nuts, and termites were potentially associated with additional divergence in microbial communities between sampling sites. Our results suggest that host genetics, geography, and climate play a far stronger role in structuring the gut microbiome in chimpanzees than in humans
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