Orbit-resolved photometry and echelle spectroscopy of the cataclysmic variable ST LMi during a 2007 high state

We present high-resolution echelle spectra and contemporaneous photometry of the polar ST LMi during a high state in 2007 March. Emission lines at Hα, He I λ5876, and He I λ7065 show similar line profiles over orbital phase and have narrow and broad components. These profile changes with phase are very similar to those reported in earlier high-state studies of ST LMi. The radial velocity curves from double Gaussian fits to the line profiles are interpreted as two crossing curves, neither of which is coincident with the orbital motion of the secondary star. We attribute one component to infall motions near the white dwarf and the other to a gas streaming along magnetic field lines connecting the two stars

Higgs Boson Mass in the Standard Model at Two-Loop Order and Beyond

We calculate the mass of the Higgs boson in the standard model in terms of the underlying Lagrangian parameters at complete 2-loop order with leading 3-loop corrections. A computer program implementing the results is provided. The program also computes and minimizes the standard model effective potential in Landau gauge at 2-loop order with leading 3-loop corrections

DNA methylation age is accelerated in alcohol dependence.

Alcohol dependence (ALC) is a chronic, relapsing disorder that increases the burden of chronic disease and significantly contributes to numerous premature deaths each year. Previous research suggests that chronic, heavy alcohol consumption is associated with differential DNA methylation patterns. In addition, DNA methylation levels at certain CpG sites have been correlated with age. We used an epigenetic clock to investigate the potential role of excessive alcohol consumption in epigenetic aging. We explored this question in five independent cohorts, including DNA methylation data derived from datasets from blood (n = 129, n = 329), liver (n = 92, n = 49), and postmortem prefrontal cortex (n = 46). One blood dataset and one liver tissue dataset of individuals with ALC exhibited positive age acceleration (p < 0.0001 and p = 0.0069, respectively), whereas the other blood and liver tissue datasets both exhibited trends of positive age acceleration that were not significant (p = 0.83 and p = 0.57, respectively). Prefrontal cortex tissue exhibited a trend of negative age acceleration (p = 0.19). These results suggest that excessive alcohol consumption may be associated with epigenetic aging in a tissue-specific manner and warrants further investigation using multiple tissue samples from the same individuals

"If We Want to Get Men in, Then We Need to Ask Men What They Want": Pathways to Effective Health Programing for Men.

In Ireland, men’s health is becoming a priority. In line with global trends, indicators of poor mental health (including rates of depression and suicide) are increasing alongside rates of unemployment and social isolation. Despite the growing awareness of men’s health as a national priority, and development of the first National Men’s Health Policy in the world, there is still a concern about men’s non-engagement with health services. Health and community services often struggle to appropriately accommodate men, and men commonly avoid health spaces. A growing body of literature suggests that a persistent lack of support or resources for service providers contributes to their inability to identify and meet men’s unique health needs. This study aims to provide further insight into the ways in which this gap between men and health services can be closed. Semi-structured, qualitative interviews were conducted with nine project partners (n=9) of a successful men’s health program in Dublin. Interviews captured reflections on what processes or strategies contribute to effective men’s health programs. Findings suggest that gender-specific strategies – especially related to community- engagement and capacity building - are necessary in creating health programs that both promote men’s health and enable men to safely and comfortably participate. Moreover, including men in all aspects of the planning stages helps to ensure that programs are accessible and acceptable for men. It is envisaged that these findings will be operationalized into a user-driven resource to illustrate evidence-informed strategies and guiding principles that could be used by practitioners hoping to engage with me

Intestinal Enterobacteriaceae that Protect Nematodes from the Effects of Benzimidazoles

The objective of this study was to investigate an interaction between nematodes and gut Enterobacteriaceae that use benzimidazoles as a carbon source. By addressing this objective, we identified an anthelmintic resistance-like mechanism for gastrointestinal nematodes. We isolated 30 gut bacteria (family Enterobacteriaceae) that subsist on and putatively catabolize benzimidazole-class anthelmintics. C. elegans was protected from the effects of benzimidazoles when co-incubated with these Enterobacteriaceae that also protect adult ascarids from the effects of albendazole. This bacterial phenotype represents a novel mechanism by which gastrointestinal nematodes are potentially spared from the effects of benzimidazoles, without any apparent fitness cost to the parasite

Hail Damage – Grain Quality Survey

There were two major hail events this summer during grain fill that resulted in significant corn crop damage in the path of the storm. The damage occurred over several thousand acres with some fields being a total loss and other fields having varying degrees of damage. This resulted in several crop hail damage meetings across the state to help farmers make informed harvest decisions. A common question from farmers and grain merchandisers dealt with grain quality issues. Specifically, what impact will the hail damage have on grain quality, ear rot severity and mycotoxin contamination in my corn crop