A biomechanical evaluation of the combined elevation test

Objectives: To biomechanically evaluate the relationships between the outcome of the Combined Elevation Test, its component joint motions, and thoracic spine angles. Design: Cross-sectional study. Setting: Laboratory. Participants: 18 elite swimmers and triathletes (11 males and 7 females). Main outcome measures: Combined Elevation Test outcome in forehead and chin positions. Individual joint contributions to test outcome. Results: No sex differences were found in test components, or between head positions. Test outcome was greater in the forehead position than the chin position (34.3 cm vs 30.2 cm; p0.05). Conclusions: The Combined Elevation Test is an effective screening tool to measure upper limb mobility into shoulder flexion and scapula retraction in both sexes, and thoracic extension in women. It is recommended that the test be performed in the forehead position. If a subject performs poorly on the test, follow up assessments are required to identify the impairment location

Bowling loads and injury risk in male first class county cricket: Is ‘differential load’ an alternative to the acute-to-chronic workload ratio?

Objectives: Methodological concerns relating to acute-to-chronic workload ratios (ACWR) have been raised. This study aimed to assess the relationship between an alternative predictor variable named ‘differential load’, representing the smoothed week-to-week rate change in load, and injury risk in first class county cricket (FCCC) fast bowlers. Design: Prospective cohort study. Methods: Bowling loads and injuries were recorded for 49 professional male fast bowlers from six FCCC teams. A range of differential loads and ACWRs were calculated and subjected to a variable selection procedure. Results: Exponentially-weighted 7-day differential load, 9:21-day ACWR, 42-day chronic load, and 9-day acute load were the best-fitting predictor variables in their respective categories. From these, a generalized linear mixed-effects model combining 7-day differential load, 42-day chronic load, and 9-day acute load provided the best model fit. A two-standard deviation (2SD) increase in 7-day differential load (22 overs) was associated with a substantial increase in injury risk (risk ratio [RR] = 2.47, 90% CI: 1.27-4.80, most likely harmful), and a 2SD increase in 42-day chronic load (17.5 overs/week) was associated with a most likely harmful increase in injury risk (RR = 6.77, 90% CI: 2.15-21.33). For 9-day acute load, very low values (≤1 over/week) were associated with a most likely higher risk of injury versus moderate (17.5 overs/week; RR: 15.50, 90% CI: 6.19-38.79) and very high 9-day acute loads (45.5 overs/week; RR: 133.33, 90% CI: 25.26-703.81). Conclusions: Differential loads may be used to identify potentially harmful spikes in load, whilst mitigating methodological issues associated with ACWRs

Passive range of motion of the hips and shoulders and their relationship with ball spin rate in elite finger spin bowlers

Objectives: Investigate rotational passive range of motion of the hips and shoulders for elite finger spin bowlers and their relationship with spin rate. Design: Correlational. Methods: Spin rates and twelve rotational range of motion measurements for the hips and shoulders were collected for sixteen elite male finger spin bowlers. Side to side differences in the rotational range of motion measurements were assessed using paired t-tests. Stepwise linear regression and Pearson product moment correlations were used to identify which range of motion measurements were linked to spin rate. Results: Side to side differences were found with more external rotation (p = 0.039) and less internal rotation (p = 0.089) in the bowling shoulder, and more internal rotation in the front hip (p = 0.041). Total arc of rotation of the front hip was found to be the best predictor of spin rate (r = 0.552, p =  0.027), explaining 26% of the observed variance. Internal rotation of the rear hip (r = 0.466, p =  0.059) and the bowling shoulder (r = 0.476, p =  0.063) were also associated with spin rate. Conclusions: The technique and performance of elite finger spin bowlers may be limited by the passive range of motion of their hips and shoulders. The observed side to side differences may indicate that due to the repetitive nature of finger spin bowling adaptive changes in the rotational range of motion of the hip and shoulder occur

A biomechanical evaluation of the combined elevation test

This paper was accepted for publication in the journal Physical Therapy in Sport and the definitive published version us available at http://dx.doi.org/10.1016/j.ptsp.2016.11.001.Objectives: To biomechanically evaluate the relationships between the outcome of the Combined Elevation Test, its component joint motions, and thoracic spine angles. Design: Cross-sectional study. Setting: Laboratory. Participants: 18 elite swimmers and triathletes (11 males and 7 females). Main outcome measures: Combined Elevation Test outcome in forehead and chin positions. Individual joint contributions to test outcome. Results: No sex differences were found in test components, or between head positions. Test outcome was greater in the forehead position than the chin position (34.3 cm vs 30.2 cm; p<0.001). The variables most strongly associated with test outcome were glenohumeral joint flexion (r = 0.86 – 0.97; p<0.001), and shoulder retraction (r = 0.75 - 0.82; p<0.001). Total thoracic spine angle related strongly to test outcome in females (r = -0.77 – -0.88; p<0.05), but not in males (r = -0.17 – -0.24; p>0.05). Conclusions: The Combined Elevation Test is an effective screening tool to measure upper limb mobility into shoulder flexion and scapula retraction in both sexes, and thoracic extension in women. It is recommended that the test be performed in the forehead position. If a subject performs poorly on the test, follow up assessments are required to identify the impairment location

Presentations of patients of poisoning and predictors of poisoning-related fatality: Findings from a hospital-based prospective study

<p>Abstract</p> <p>Background</p> <p>Poisoning is a significant public health problem worldwide and is one of the most common reasons for visiting emergency departments (EDs), but factors that help to predict overall poisoning-related fatality have rarely been elucidated. Using 1512 subjects from a hospital-based study, we sought to describe the demographic and clinical characteristics of poisoning patients and to identify predictors for poisoning-related fatality.</p> <p>Methods</p> <p>Between January 2001 and December 2002 we prospectively recruited poisoning patients through the EDs of two medical centers in southwest Taiwan. Interviews were conducted with patients within 24 hours after admission to collect relevant information. We made comparisons between survival and fatality cases, and used logistic regressions to identify predictors of fatality.</p> <p>Results</p> <p>A total of 1512 poisoning cases were recorded at the EDs during the study period, corresponding to an average of 4.2 poisonings per 1000 ED visits. These cases involved 828 women and 684 men with a mean age of 38.8 years, although most patients were between 19 and 50 years old (66.8%), and 29.4% were 19 to 30 years. Drugs were the dominant poisoning agents involved (49.9%), followed by pesticides (14.5%). Of the 1512 patients, 63 fatalities (4.2%) occurred. Paraquat exposure was associated with an extremely high fatality rate (72.1%). The significant predictors for fatality included age over 61 years, insufficient respiration, shock status, abnormal heart rate, abnormal body temperature, suicidal intent and paraquat exposure.</p> <p>Conclusion</p> <p>In addition to well-recognized risk factors for fatality in clinical settings, such as old age and abnormal vital signs, we found that suicidal intent and ingestion of paraquat were significant predictors of poisoning-related fatality. Identification of these predictors may help risk stratification and the development of preventive interventions.</p

Fludarabine, cytarabine, granulocyte colony-stimulating factor, and idarubicin with gemtuzumab ozogamicin improves event-free survival in younger patients with newly diagnosed aml and overall survival in patients with npm1 and flt3 mutations

Purpose To determine the optimal induction chemotherapy regimen for younger adults with newly diagnosed AML without known adverse risk cytogenetics. Patients and Methods One thousand thirty-three patients were randomly assigned to intensified (fludarabine, cytarabine, granulocyte colony-stimulating factor, and idarubicin [FLAG-Ida]) or standard (daunorubicin and Ara-C [DA]) induction chemotherapy, with one or two doses of gemtuzumab ozogamicin (GO). The primary end point was overall survival (OS). Results There was no difference in remission rate after two courses between FLAG-Ida + GO and DA + GO (complete remission [CR] + CR with incomplete hematologic recovery 93% v 91%) or in day 60 mortality (4.3% v 4.6%). There was no difference in OS (66% v 63%; P = .41); however, the risk of relapse was lower with FLAG-Ida + GO (24% v 41%; P < .001) and 3-year event-free survival was higher (57% v 45%; P < .001). In patients with an NPM1 mutation (30%), 3-year OS was significantly higher with FLAG-Ida + GO (82% v 64%; P = .005). NPM1 measurable residual disease (MRD) clearance was also greater, with 88% versus 77% becoming MRD-negative in peripheral blood after cycle 2 (P = .02). Three-year OS was also higher in patients with a FLT3 mutation (64% v 54%; P = .047). Fewer transplants were performed in patients receiving FLAG-Ida + GO (238 v 278; P = .02). There was no difference in outcome according to the number of GO doses, although NPM1 MRD clearance was higher with two doses in the DA arm. Patients with core binding factor AML treated with DA and one dose of GO had a 3-year OS of 96% with no survival benefit from FLAG-Ida + GO. Conclusion Overall, FLAG-Ida + GO significantly reduced relapse without improving OS. However, exploratory analyses show that patients with NPM1 and FLT3 mutations had substantial improvements in OS. By contrast, in patients with core binding factor AML, outcomes were excellent with DA + GO with no FLAG-Ida benefit

Training and injuries among world elite junior badminton players – Identifying the problems

Background: The game of badminton has evolved since the early injury epidemiology studies. Since there is no published literature on injuries in elite junior badminton players from an international cohort, this study provides an updated reference of injuries in this population to inform future injury prevention strategies. The objective of this study was to report injury prevalence and training hours in elite junior badminton players participating at the World Junior Championships in 2018. Methods: A questionnaire was used to collect data and was available in English, French, Spanish, Korean, Japanese or Chinese. It was designed to collect information including basic demographics, hours of training and competition, number of tournaments per year, current and previous injuries characterized by anatomical region, diagnosis, treatment and injury duration. The questions were focused on previous significant injuries lasting a minimum of 30 days and current musculoskeletal symptoms. Results: One hundred and sixty-four of 436 players with a mean age of 17.1 years (SD ± 0.8) filled in the questionnaire. Participants represented North and South America, Europe, Asia, Africa and The Pacific's including the top 10 performing nations, providing a good overall representation of tournament participants. A total of 104 significant injuries (median duration of 90 days) with disruption of full training or competition capacity were reported. Seventy-eight (48%) players reported one or more significant injury. The most common location of significant injury was in the knee, ankle and lower back. Eleven injuries were reported as stress fractures. In 35 cases a player felt lasting limitation from a significant injury and in 37 cases a player felt lasting pain. Conclusion: Previously in their career almost 50% of the players had sustained a significant injury with a median duration of 90 days. The lower extremities and the lower back were the predominant injured regions. In one third of the injuries a player had lasting limitations or pain. Stress fractures may be a serious underestimated problem in badminton

Supplementary information files for Lumbar bone stress injuries and risk factors in adolescent cricket fast bowlers

Supplementary files for article Lumbar bone stress injuries and risk factors in adolescent cricket fast bowlers Cricket fast bowling is associated with a high prevalence of lumbar bone stress injuries (LBSI), especially in adolescent bowlers. This has not been sufficiently explained by risk factors identified in adult players. This study aimed to examine the incidence of LBSI in adolescent fast bowlers over a prospective study and potential risk factors. Forty asymptomatic male fast bowlers (aged 14–17 years) received baseline and annual lumbar dual-energy X-ray absorptiometry (DXA) and magnetic resonance imaging (MRI) scans, and musculoskeletal and bowling workload assessment; 22 were followed up after one year. LBSI prevalence at baseline and annual incidence were calculated. Potential risk factors were compared between the injured and uninjured groups using T-tests with Hedges’ g effect sizes. At baseline, 20.5% of participants had at least one LBSI. Subsequent LBSI incidence was 27.3 ± 18.6 injuries per 100 players per year (mean ± 95% CI). Injured bowlers were older on average at the beginning of the season preceding injury (16.8 versus 15.6 years, g = 1.396, P = 0.047). LBSI risk may coincide with increases in bowling workload and intensity as bowlers step up playing levels to more senior teams during late adolescence whilst the lumbar spine is immature and less robust. </p

Lumbar bone stress injuries and risk factors in adolescent cricket fast bowlers

Cricket fast bowling is associated with a high prevalence of lumbar bone stress injuries (LBSI), especially in adolescent bowlers. This has not been sufficiently explained by risk factors identified in adult players. This study aimed to examine the incidence of LBSI in adolescent fast bowlers over a prospective study and potential risk factors. Forty asymptomatic male fast bowlers (aged 14–17 years) received baseline and annual lumbar dual-energy X-ray absorptiometry (DXA) and magnetic resonance imaging (MRI) scans, and musculoskeletal and bowling workload assessment; 22 were followed up after one year. LBSI prevalence at baseline and annual incidence were calculated. Potential risk factors were compared between the injured and uninjured groups using T-tests with Hedges’ g effect sizes. At baseline, 20.5% of participants had at least one LBSI. Subsequent LBSI incidence was 27.3 ± 18.6 injuries per 100 players per year (mean ± 95% CI). Injured bowlers were older on average at the beginning of the season preceding injury (16.8 versus 15.6 years, g = 1.396, P = 0.047). LBSI risk may coincide with increases in bowling workload and intensity as bowlers step up playing levels to more senior teams during late adolescence whilst the lumbar spine is immature and less robust