5,737 research outputs found
On the Composition of Gauge Structures
A formulation for a non-trivial composition of two classical gauge structures
is given: Two parent gauge structures of a common base space are synthesized so
as to obtain a daughter structure which is fundamental by itself. The model is
based on a pair of related connections that take their values in the product
space of the corresponding Lie algebras. The curvature, the covariant exterior
derivatives and the associated structural identities, all get contributions
from both gauge groups. The various induced structures are classified into
those whose composition is given just by trivial means, and those which possess
an irreducible nature. The pure irreducible piece, in particular, generates a
complete super-space of ghosts with an attendant set of super-BRST variation
laws, both of which are purely of a geometrical origin.Comment: Few elaborations are added to section 4 and section 5. To be
published in Journal of Physics A: Mathematical and General. 21 page
Symmetric mixed states of qubits: local unitary stabilizers and entanglement classes
We classify, up to local unitary equivalence, local unitary stabilizer Lie
algebras for symmetric mixed states into six classes. These include the
stabilizer types of the Werner states, the GHZ state and its generalizations,
and Dicke states. For all but the zero algebra, we classify entanglement types
(local unitary equivalence classes) of symmetric mixed states that have those
stabilizers. We make use of the identification of symmetric density matrices
with polynomials in three variables with real coefficients and apply the
representation theory of SO(3) on this space of polynomials.Comment: 10 pages, 1 table, title change and minor clarifications for
published versio
Text mining meets community curation: a newly designed curation platform to improve author experience and participation at WormBase
Biological knowledgebases rely on expert biocuration of the research literature to maintain up-to-date collections of data organized in machine-readable form. To enter information into knowledgebases, curators need to follow three steps: (i) identify papers containing relevant data, a process called triaging; (ii) recognize named entities; and (iii) extract and curate data in accordance with the underlying data models. WormBase (WB), the authoritative repository for research data on Caenorhabditis elegans and other nematodes, uses text mining (TM) to semi-automate its curation pipeline. In addition, WB engages its community, via an Author First Pass (AFP) system, to help recognize entities and classify data types in their recently published papers. In this paper, we present a new WB AFP system that combines TM and AFP into a single application to enhance community curation. The system employs string-searching algorithms and statistical methods (e.g. support vector machines (SVMs)) to extract biological entities and classify data types, and it presents the results to authors in a web form where they validate the extracted information, rather than enter it de novo as the previous form required. With this new system, we lessen the burden for authors, while at the same time receive valuable feedback on the performance of our TM tools. The new user interface also links out to specific structured data submission forms, e.g. for phenotype or expression pattern data, giving the authors the opportunity to contribute a more detailed curation that can be incorporated into WB with minimal curator review. Our approach is generalizable and could be applied to additional knowledgebases that would like to engage their user community in assisting with the curation. In the five months succeeding the launch of the new system, the response rate has been comparable with that of the previous AFP version, but the quality and quantity of the data received has greatly improved
Benchmarks of the full configuration interaction, Monte Carlo shell model, and no-core full configuration methods
We report no-core solutions for properties of light nuclei with three
different approaches in order to assess the accuracy and convergence rates of
each method. Full configuration interaction (FCI), Monte Carlo shell model
(MCSM) and no core full configuration (NCFC) approaches are solved separately
for the ground state energy and other properties of seven light nuclei using
the realistic JISP16 nucleon-nucleon interaction. The results are consistent
among the different approaches. The methods differ significantly in how the
required computational resources scale with increasing particle number for a
given accuracy.Comment: 19 pages, 14 figures, 6 table
Climate-dependent CO2 emissions from lakes
Inland waters, just as the world's oceans, play an important role in the global carbon cycle. While lakes and reservoirs typically emit CO2, they also bury carbon in their sediment. The net CO2 emission is largely the result of the decomposition or preservation of terrestrially supplied carbon. What regulates the balance between CO2 emission and carbon burial is not known, but climate change and temperature have been hypothesized to influence both processes. We analyzed patterns in carbon dioxide partial pressure (pCO2) in 83 shallow lakes over a large climatic gradient in South America and found a strong, positive correlation with temperature. The higher pCO2 in warmer lakes may be caused by a higher, temperature-dependent mineralization of organic carbon. This pattern suggests that cool lakes may start to emit more CO2 when they warm up because of climate ch
Is gastro-oesophageal reflux a factor in exercise-induced asthma?
AbstractExercise-induced bronchoconstriction (EIB) occurs in the majority of patients with asthma. The relationship between asthma and gastro-oesophageal reflux (GER) is well defined, and the reports of exertional gastro-oesophageal acid reflux in healthy subjects, prompted us to study the relationship between EIB and GER.Following an overnight fast and medication withholding, 15 asthmatics and 15 normal subjects were placed on continuous monitoring of oesophageal pH and ECG. After baseline monitoring of oesophageal pH, at rest, for 30 min, spirometry was performed. Thereafter, the subjects underwent rigorous treadmill exercise for 8 min followed by spirometry, 10 min after running.Twelve out of 15 asthmatics and none in the control group demonstrated significant fall in FEV1 in response to exercise. However, only six out of 15 normal subjects and three in the asthmatic group had evidence of GER during or following exercise.We concluded that there is no significant correlation between EIB and GER in patients with asthma
A Policy Impact Evaluation Model For Scotland: Decoupling Single Farm Payments
The purpose of this paper is to assess the impacts of decoupling single farm payments in Scotland. It focuses on aggregate impacts on the agricultural products in domestic and external markets and the spill-over effect of this on the non-agricultural sector as well as an aggregate impact on the Scottish GDP. In order to capture system-wide impacts of the policy reform, a CGE model was formulated and implemented using a social accounting matrix constructed for Scotland. The simulation results suggest that the Scottish agricultural sector may encounter declines in output and factor us as a result of the policy reform. However, this critically depends on two factors: (a) the price effect of the policy reform on Scottish agricultural products relative to the EU average as well as the conditions of changes in world agricultural market prices; and (b) the extent to which customers would be sensitive to price effects of the policy reform. As far as the spill-over effect to the non-agricultural sector is concerned, decoupling of direct payments seems to have a positive spill-over effect. Similarly, the aggregate GDP effect is positive under all simulation scenarios. Critically, the simulation experiments indicate that policy shock may have a symmetrical outcome across the two sectors, with contractions in agriculture being accompanied by expansions in the non-agricultural sector, mainly because of factor market interactions between the two sectors.
SINFONI Integral Field Spectroscopy of z~2 UV-selected Galaxies: Rotation Curves and Dynamical Evolution
We present 0.5" resolution near-IR integral field spectroscopy of the Ha line
emission of 14 z~2 UV-selected BM/BX galaxies obtained with SINFONI at ESO/VLT.
The mean Ha half-light radius r_1/2 is about 4kpc and line emission is detected
over > ~20kpc in several sources. In 9 sources, we detect spatially-resolved
velocity gradients, from 40 to 410 km/s over ~10kpc. The observed kinematics of
the larger systems are consistent with orbital motions. Four galaxies are well
described by rotating disks with clumpy morphologies and we extract rotation
curves out to radii > ~10kpc. One or two galaxies exhibit signatures more
consistent with mergers. Analyzing all 14 galaxies in the framework of rotating
disks, we infer mean inclination- and beam-corrected maximum circular
velocities v_c of 180+-90 km/s and dynamical masses of (0.5-25)x10^10 Msun
within r_1/2. On average, the dynamical masses are consistent with photometric
stellar masses assuming a Chabrier/Kroupa IMF but too small for a 0.1-100 Msun
Salpeter IMF. The specific angular momenta of our BM/BX galaxies are similar to
those of local late-type galaxies. The specific angular momenta of their
baryons are comparable to those of their dark matter halos. Extrapolating from
the average v_c at 10kpc, the virial mass of the typical halo of a galaxy in
our sample is 10^(11.7+-0.5) Msun. Kinematic modeling of the 3 best cases
implies a ratio of v_c to local velocity dispersion of order 2-4 and
accordingly a large geometric thickness. We argue that this suggests a mass
accretion (alternatively, gas exhaustion) timescale of ~500Myr. We also argue
that if our BM/BX galaxies were initially gas rich, their clumpy disks will
subsequently lose their angular momentum and form compact bulges on a timescale
of ~1 Gyr. [ABRIDGED]Comment: Accepted for publication in the Astrophysical Journal. 17 pages, 5
color figure
Trace formulas for stochastic evolution operators: Smooth conjugation method
The trace formula for the evolution operator associated with nonlinear
stochastic flows with weak additive noise is cast in the path integral
formalism. We integrate over the neighborhood of a given saddlepoint exactly by
means of a smooth conjugacy, a locally analytic nonlinear change of field
variables. The perturbative corrections are transfered to the corresponding
Jacobian, which we expand in terms of the conjugating function, rather than the
action used in defining the path integral. The new perturbative expansion which
follows by a recursive evaluation of derivatives appears more compact than the
standard Feynman diagram perturbation theory. The result is a stochastic analog
of the Gutzwiller trace formula with the ``hbar'' corrections computed an order
higher than what has so far been attainable in stochastic and
quantum-mechanical applications.Comment: 16 pages, 1 figure, New techniques and results for a problem we
considered in chao-dyn/980703
Tissue enrichment analysis for C. elegans genomics
Background: Over the last ten years, there has been explosive development in methods for measuring gene expression. These methods can identify thousands of genes altered between conditions, but understanding these datasets and forming hypotheses based on them remains challenging. One way to analyze these datasets is to associate ontologies (hierarchical, descriptive vocabularies with controlled relations between terms) with genes and to look for enrichment of specific terms. Although Gene Ontology (GO) is available for Caenorhabditis elegans, it does not include anatomical information.
Results: We have developed a tool for identifying enrichment of C. elegans tissues among gene sets and generated a website GUI where users can access this tool. Since a common drawback to ontology enrichment analyses is its verbosity, we developed a very simple filtering algorithm to reduce the ontology size by an order of magnitude. We adjusted these filters and validated our tool using a set of 30 gold standards from Expression Cluster data in WormBase. We show our tool can even discriminate between embryonic and larval tissues and can even identify tissues down to the single-cell level. We used our tool to identify multiple neuronal tissues that are down-regulated due to pathogen infection in C. elegans.
Conclusions: Our Tissue Enrichment Analysis (TEA) can be found within WormBase, and can be downloaded using Python’s standard pip installer. It tests a slimmed-down C. elegans tissue ontology for enrichment of specific terms and provides users with a text and graphic representation of the results
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