1,645 research outputs found

    Fourth Aircraft Interior Noise Workshop

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    The fourth in a series of NASA/SAE Interior Noise Workshops was held on May 19 and 20, 1992. The theme of the workshop was new technology and applications for aircraft noise with emphasis on source noise prediction; cabin noise prediction; cabin noise control, including active and passive methods; and cabin interior noise procedures. This report is a compilation of the presentations made at the meeting which addressed the above issues

    Investigation of the Damping of Liquids in Right-Circular Cylindrical Tanks, Including the Effects of a Time-Variant Liquid Depth

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    An experimental investigation was conducted to determine the effects of several basic variables upon the damping of the fundamental antisymmetric mode of liquids in right-circular cylindrical tanks without baffles. The variables examined include liquid depth, efflux rate, liquid amplitude, kinematic viscosity, and tank size. The data are presented in dimensionless form and compared with available theory. For the range of variables examined, variations of efflux rate and liquid amplitude were found to have no significant effects on the liquid damping. The following theoretical relationship was found to be adequate for the prediction of the variation of damping with liquid depth, kinematic viscosity, and tank size: [for equation see full text] where v is the kinematic viscosity, R is the cylinder radius, g is the acceleration due to gravity, and h is the liquid depth. However, the constant K was experimentally found in this investigation to have the value 5.23, which is 50 percent higher than the theoretically predicted value

    One-Pot Synthesis of Bicyclic Piperidines from Donor Acceptor Cyclopropanes

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    The efficient synthesis of heterocyclic compounds is of great importance to organic chemistry. One method for achieving efficiency is through the use and development of one-pot reactions. This thesis describes the planning and development of an extension to the tandem cyclopropane opening Conia-ene reactivity previously reported. A search for a substrate capable of undergoing the reaction was undertaken and the reaction was optimized. The highest yielding conditions tested used catalytic Sc(OTf)3 and superstoichiometric ZnBr2, but other catalyst systems also worked. The optimized reaction conditions tolerated 6-membered rings well in addition to 7-membered rings in some rotationally restricted cases. Heteroatom linkers such as oxygen and protected amines were also well tolerated. This protocol provides efficient access to bicyclic piperidines that can be mapped onto natural products

    Cell biology:Collagen secretion explained

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    Cells package proteins into vesicles for secretion to the extracellular milieu. A study shows that an enzyme modifies the packaging machinery to encapsulate unusually large proteins such as collagen

    An Experimental Investigation of the Damping of Liquid Oscillations in an Oblate Spheroidal Tank With and Without Baffles

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    An experimental investigation was conducted to determine the damping of the fundamental antisymmetric mode of oscillation of liquids contained in an oblate spheroidal tank. The decay of the fundamental mode was studied for a range of liquid depths in tanks with and without baffles. In the investigation of baffle effects, ring and cruciform baffles of various sizes were fixed at different locations within the tank. Data presented show the variation of the damping factor with tank fullness and with baffle type, width, location, and orientation as well as the effects of the amplitude of the liquid oscillations and of small variations in the liquid kinematic viscosity on the damping factor. The results of the investigation indicate that the addition of ring baffles to the tank results in an increase in the available effective damping when the baffle plane is in a region near the equilibrium liquid surface, and that cruciform baffles are effective in the damping of the fundamental mode in the near-empty tank. No apparent changes in damping for the tanks having ring baffles were observed as the kinematic viscosity of the liquid was varied over a small range

    Near-Infrared Photoluminescence and Electrochemiluminescence from an Exceptionally Simple Boron Difluoride Formazanate Dye

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    Electrochemiluminescence involves the generation of light via electrochemical reactions and has recently shown utility for single-cell imaging. To further develop this novel imaging platform, it is necessary to produce readily available dyes that photoluminesce and electrochemiluminesce in the near-infrared region to limit absorption by biological tissue. To address this need, we prepared a boron difluoride formazanate dye that exhibits near-infrared photoluminescence and electrochemiluminescence in two straightforward synthetic steps. Examination of its solid-state structure suggests that the N-aryl substituents have significant quinoidal character, which narrows the S1-S0 energy gap and leads to near-infrared absorption and photoluminescence. Electrochemical properties were probed using cyclic voltammetry and revealed four electrochemically reversible waves. Electrochemiluminescence properties were examined in the presence of tri-n-propylamine, leading to maximum intensity at 910 nm, at least 85 nm (1132 cm‒1) red-shifted compared to all other organic dyes. This work sets the stage for the development of future generations of dyes for emerging applications, including single-cell imaging, that require near-infrared photoluminescence and electrochemiluminescence

    Cytoplasmic dynein-2 at a glance

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    Symbiodinium genomes reveal adaptive evolution of functions related to coral-dinoflagellate symbiosis

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    Symbiosis between dinoflagellates of the genus Symbiodinium and reef-building corals forms the trophic foundation of the world’s coral reef ecosystems. Here we present the first draft genome of Symbiodinium goreaui (Clade C, type C1: 1.03 Gbp), one of the most ubiquitous endosymbionts associated with corals, and an improved draft genome of Symbiodinium kawagutii (Clade F, strain CS-156: 1.05 Gbp) to further elucidate genomic signatures of this symbiosis. Comparative analysis of four available Symbiodinium genomes against other dinoflagellate genomes led to the identification of 2460 nuclear gene families (containing 5% of Symbiodinium genes) that show evidence of positive selection, including genes involved in photosynthesis, transmembrane ion transport, synthesis and modification of amino acids and glycoproteins, and stress response. Further, we identify extensive sets of genes for meiosis and response to light stress. These draft genomes provide a foundational resource for advancing our understanding of Symbiodinium biology and the coral-algal symbiosis.H.L. was supported by an Australian Research Council grant (DP150101875) awarded to M.A. R. and C.X.C. T.G.S. is supported by an Australian Government Research Training Program Scholarship. R.A.G.-P. is supported by an International Postgraduate Research Scholarship and a University of Queensland Centenary Scholarship. This project was supported by the computational resources of the Australian National Computational Infrastructure (NCI) National Facility systems through the NCI Merit Allocation Scheme (Project d85) awarded to M.A.R. and C.X.C. The data used in this project were funded by the Great Barrier Reef Foundation’s Resilient Coral Reefs Successfully Adapting to Climate Change research and development program in collaboration with the Australian Government, Bioplatforms Australia through the National Collaborative Research Infrastructure Strategy (NCRIS), Rio Tinto and a family foundation. The authors also acknowledge the work done by the Reef Future Genomics (ReFuGe) 2020 Consortium. Access to data generated by the consortium can be accessed via reefgenomics.org. In memory of S.F., our friend and colleague who is sorely missed
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