Touch in the Time of Corona

The COVID-19 pandemic has hooked us all into digital networks as our access to cities, work and social gatherings is restricted and reconfigured. Weaving together cultural history, aesthetics, and urban and digital studies, this short volume reflects on how the possibilities for touch, touching and being touched, both physically and affectively, are reconfigured by the pandemic

Touch in the Time of Corona

The COVID-19 pandemic has hooked us all into digital networks as our access to cities, work and social gatherings is restricted and reconfigured. Weaving together cultural history, aesthetics, and urban and digital studies, this short volume reflects on how the possibilities for touch, touching and being touched, both physically and affectively, are reconfigured by the pandemic

Doubling Energy Efficiency at the University of Michigan by 2030

Approximately 84 million Americans spend their days in colleges, universities, and public or private primary and secondary schools.ii The commercial building sector, which includes educational institutions, accounts for 18.44 percent of overall energy consumption in the United States.iii Education buildings are ranked third highest of all commercial buildings, consuming over 600 trillion Btus of energy each year.iv Given these consumption levels, educational institutions have an opportunity to make a significant impact to increase energy efficiency in this country. The University of Michigan (herein, also “the University” or “UM”) has been working diligently to be leaders in this charge. In 2012, the Alliance to Save Energy proposed a goal of doubling energy productivity in the United States by 2030, thereby getting twice as much economic output for every unit of energy input.v This goal inspired Johnson Controls, Inc. (herein, “Johnson Controls” or “JCI”) to approach the University with a Master’s Project, enabling a group of students to learn from the expertise of Johnson Controls, and to be active participants in sustainability efforts at the University of Michigan. Additionally, the findings and recommendations developed to increase energy productivity on campus should likely contribute towards the University’s existing sustainability goal of reducing greenhouse gas (GHG) emissions. This project seeks to harness the knowledge, technology and best practices honed by Johnson Controls from decades of experience in energy conservation projects, as well as the expertise from the University of Michigan, including various professionals and organizations that actively work towards energy efficiency measures on campus. Leveraging these and other resources, our six graduate student member team (Appendix A) analyzed the University of Michigan’s current energy demand and management. We learned about the extensive work the energy management team has already been doing for several decades in some areas on campus, and about what opportunities there are for improvement. Our master's project team identified several recommendations for furthering the collective energy efficiency performance of the University, as well as recommendations on measures that can be taken in the Samuel T. Dana building (herein, the “Dana building”), which serves as a case study for the project. The key findings and recommendations, both campus-wide and for the Dana building, are detailed here.Master of ScienceNatural Resources and EnvironmentUniversity of Michiganhttp://deepblue.lib.umich.edu/bitstream/2027.42/117588/3/Doubling Energy Efficiency at the University of Michigan by 2030.pd

Carbon Origami via an Alumina-Assisted Cyclodehydrofluorination Strategy

The synthesis of pristine non‐planar nanographenes (NGs) via a cyclodehydrofluorination strategy is reported and the creation of highly strained systems via alumina‐assisted C−F bond activation is shown. Steric hindrance could execute an alternative coupling program leading to rare octagon formation offering access to elusive non‐classical NGs. The combination of two alternative ways of folding could lead to the formation of various 3D NG objects, resembling the Japanese art of origami. The power of the presented “origami” approach is proved by the assembly of 12 challenging nanographenes that are π‐isoelectronic to planar hexabenzocoronene but forced out of planarity

(1S,2S,6S,9S)-6-Methyl-5-oxobicyclo­[4.4.0]decane-2,9-diyl diacetate

The chiral title compound, C15H22O5, is an inter­mediate in the total synthesis of biologically active 9,11-secosterols. In the crystal, the cyclo­hexane rings are trans-fused and both adopt chair conformations. In the crystal, mol­ecules are loosely held together in a layer parallel to (100) by weak inter­molcular C—H⋯O hydrogen bonds accepted by carbonyl O atoms of the acetyl groups

On the Spin of the Black Hole in IC 10 X-1

The compact X-ray source in the eclipsing X-ray binary IC 10 X–1 has reigned for years as ostensibly the most massive stellar-mass black hole, with a mass estimated to be about twice that of its closest rival. However, striking results presented recently by Laycock et al. reveal that the mass estimate, based on emission-line velocities, is unreliable and that the mass of the X-ray source is essentially unconstrained. Using Chandra and NuSTAR data, we rule against a neutron-star model and conclude that IC 10 X–1 contains a black hole. The eclipse duration of IC 10 X–1 is shorter and its depth shallower at higher energies, an effect consistent with the X-ray emission being obscured during eclipse by a Compton-thick core of a dense wind. The spectrum is strongly disk-dominated, which allows us to constrain the spin of the black hole via X-ray continuum fitting. Three other wind-fed black hole systems are known; the masses and spins of their black holes are high: M ~ 10 - 15M_☉ and ɑ_* > 0.8. If the mass of IC 10 X-1's black hole is comparable, then its spin is likewise high

On the Origin of the Treponematoses: A Phylogenetic Approach

For 500 years, controversy has raged around the origin of T. pallidum subsp. pallidum, the bacterium responsible for syphilis. Did Christopher Columbus and his men introduce this pathogen into Renaissance Europe, after contracting it during their voyage to the New World? Or does syphilis have a much older history in the Old World? This paper represents the first attempt to use a phylogenetic approach to solve this question. In addition, it clarifies the evolutionary relationships between the pathogen that causes syphilis and the other T. pallidum subspecies, which cause the neglected tropical diseases yaws and endemic syphilis. Using a collection of pathogenic Treponema strains that is unprecedented in size, we show that yaws appears to be an ancient infection in humans while venereal syphilis arose relatively recently in human history. In addition, the closest relatives of syphilis-causing strains identified in this study were found in South America, providing support for the Columbian theory of syphilis's origin

The 2017 Failed Outburst of GX 339-4: Relativistic X-ray Reflection near the Black Hole Revealed by NuSTAR and Swift Spectroscopy

We report on the spectroscopic analysis of the black hole binary GX 339−4 during its recent 2017–2018 outburst, observed simultaneously by the Swift and NuSTAR observatories. Although during this particular outburst the source failed to make state transitions, and despite Sun constraints during the peak luminosity, we were able to trigger four different observations sampling the evolution of the source in the hard state. We show that even for the lowest-luminosity observations the NuSTAR spectra show clear signatures of X-ray reprocessing (reflection) in an accretion disk. Detailed analysis of the highest signal-to-noise spectra with our family of relativistic reflection models RELXILL indicates the presence of both broad and narrow reflection components. We find that a dual-lamppost model provides a superior fit when compared to the standard single lamppost plus distant neutral reflection. In the dual-lamppost model two sources at different heights are placed on the rotational axis of the black hole, suggesting that the narrow component of the Fe K emission is likely to originate in regions far away in the disk, but still significantly affected by its rotational motions. Regardless of the geometry assumed, we find that the inner edge of the accretion disk reaches a few gravitational radii in all our fits, consistent with previous determinations at similar luminosity levels. This confirms a very low degree of disk truncation for this source at luminosities above ~1% Eddington. Our estimates of R_(in) reinforce the suggested behavior for an inner disk that approaches the innermost regions as the luminosity increases in the hard state

Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

Source at https://doi.org/10.1016/S0140-6736(18)32335-3. NB only authors with Norwegian affiliation registered in Munin. See source for full author list.Background - How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, and provision of services. We comparatively assessed the patterns and trends of healthy life expectancy (HALE), which quantifies the number of years of life expected to be lived in good health, and the complementary measure of disability-adjusted life-years (DALYs), a composite measure of disease burden capturing both premature mortality and prevalence and severity of ill health, for 359 diseases and injuries for 195 countries and territories over the past 28 years. Methods - We used data for age-specific mortality rates, years of life lost (YLLs) due to premature mortality, and years lived with disability (YLDs) from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 to calculate HALE and DALYs from 1990 to 2017. We calculated HALE using age-specific mortality rates and YLDs per capita for each location, age, sex, and year. We calculated DALYs for 359 causes as the sum of YLLs and YLDs. We assessed how observed HALE and DALYs differed by country and sex from expected trends based on Socio-demographic Index (SDI). We also analysed HALE by decomposing years of life gained into years spent in good health and in poor health, between 1990 and 2017, and extra years lived by females compared with males. Findings - Globally, from 1990 to 2017, life expectancy at birth increased by 7·4 years (95% uncertainty interval 7·1–7·8), from 65·6 years (65·3–65·8) in 1990 to 73·0 years (72·7–73·3) in 2017. The increase in years of life varied from 5·1 years (5·0–5·3) in high SDI countries to 12·0 years (11·3–12·8) in low SDI countries. Of the additional years of life expected at birth, 26·3% (20·1–33·1) were expected to be spent in poor health in high SDI countries compared with 11·7% (8·8–15·1) in low-middle SDI countries. HALE at birth increased by 6·3 years (5·9–6·7), from 57·0 years (54·6–59·1) in 1990 to 63·3 years (60·5–65·7) in 2017. The increase varied from 3·8 years (3·4–4·1) in high SDI countries to 10·5 years (9·8–11·2) in low SDI countries. Even larger variations in HALE than these were observed between countries, ranging from 1·0 year (0·4–1·7) in Saint Vincent and the Grenadines (62·4 years [59·9–64·7] in 1990 to 63·5 years [60·9–65·8] in 2017) to 23·7 years (21·9–25·6) in Eritrea (30·7 years [28·9–32·2] in 1990 to 54·4 years [51·5–57·1] in 2017). In most countries, the increase in HALE was smaller than the increase in overall life expectancy, indicating more years lived in poor health. In 180 of 195 countries and territories, females were expected to live longer than males in 2017, with extra years lived varying from 1·4 years (0·6–2·3) in Algeria to 11·9 years (10·9–12·9) in Ukraine. Of the extra years gained, the proportion spent in poor health varied largely across countries, with less than 20% of additional years spent in poor health in Bosnia and Herzegovina, Burundi, and Slovakia, whereas in Bahrain all the extra years were spent in poor health. In 2017, the highest estimate of HALE at birth was in Singapore for both females (75·8 years [72·4–78·7]) and males (72·6 years [69·8–75·0]) and the lowest estimates were in Central African Republic (47·0 years [43·7–50·2] for females and 42·8 years [40·1–45·6] for males). Globally, in 2017, the five leading causes of DALYs were neonatal disorders, ischaemic heart disease, stroke, lower respiratory infections, and chronic obstructive pulmonary disease. Between 1990 and 2017, age-standardised DALY rates decreased by 41·3% (38·8–43·5) for communicable diseases and by 49·8% (47·9–51·6) for neonatal disorders. For non-communicable diseases, global DALYs increased by 40·1% (36·8–43·0), although age-standardised DALY rates decreased by 18·1% (16·0–20·2). Interpretation - With increasing life expectancy in most countries, the question of whether the additional years of life gained are spent in good health or poor health has been increasingly relevant because of the potential policy implications, such as health-care provisions and extending retirement ages. In some locations, a large proportion of those additional years are spent in poor health. Large inequalities in HALE and disease burden exist across countries in different SDI quintiles and between sexes. The burden of disabling conditions has serious implications for health system planning and health-related expenditures. Despite the progress made in reducing the burden of communicable diseases and neonatal disorders in low SDI countries, the speed of this progress could be increased by scaling up proven interventions. The global trends among non-communicable diseases indicate that more effort is needed to maximise HALE, such as risk prevention and attention to upstream determinants of health