Large cell anaplastic lypmhoma versus Hodgkin's disease – difficulties in the diagnosis

AbstractDuring the last 5 years in the Polish Children's Leukemia/Lymphoma Study Group (7 centers) 241 children with Hodgkin's Disease and 14 children with Large Cell Anaplastic Lymphoma were treated.In 5 of them we had problems with differential diagnosis.Immunohistochemical tests:–CD30 positive, CD15 positive, LCA negative allowed us to change the diagnosis from Large Cell Anaplastic Lymphoma to Hodgkin's Disease (one child) and–CD30 positive, CD15 negative from Hodgkin's Disease to Large Cell Anaplastic Lymphoma (four children).All children achieved remission after changing the protocol of chemotherapy

Angioleiomyosarcoma – a very rare malignant tumour from the soft tissue

In the article we describe a case of a 12-year old boy with the tumour in the small pelvis. The only one abnormality in laboratory tests was a 3-numeral ESR and a big solid tumour probably extended from the urine bowel, found on radiological examination. On surgery the tumour was found to extend from the ascendent colon. On pathological examination, it was described as angioleiomyosarcoma with metastases in the lymph nodes. The boy was treated with IX courses consisting of ifosfamide, vepeside or ifosfamide, adriamycine and vincristine. At present, the child is in the first complete remission, 7 months after completion chemotherapy

Large cell anaplastic lypmhoma versus Hodgkin's disease – difficulties in the diagnosis

During the last 5 years in the Polish Children's Leukemia/Lymphoma Study Group (7 centers) 241 children with Hodgkin's Disease and 14 children with Large Cell Anaplastic Lymphoma were treated.In 5 of them we had problems with differential diagnosis.Immunohistochemical tests:–CD30 positive, CD15 positive, LCA negative allowed us to change the diagnosis from Large Cell Anaplastic Lymphoma to Hodgkin's Disease (one child) and–CD30 positive, CD15 negative from Hodgkin's Disease to Large Cell Anaplastic Lymphoma (four children).All children achieved remission after changing the protocol of chemotherapy

Globetrotting strangles: the unbridled national and international transmission of Streptococcus equi between horses.

The equine disease strangles, which is characterized by the formation of abscesses in the lymph nodes of the head and neck, is one of the most frequently diagnosed infectious diseases of horses around the world. The causal agent, Streptococcus equi subspecies equi, establishes a persistent infection in approximately 10 % of animals that recover from the acute disease. Such 'carrier' animals appear healthy and are rarely identified during routine veterinary examinations pre-purchase or transit, but can transmit S. equi to naïve animals initiating new episodes of disease. Here, we report the analysis and visualization of phylogenomic and epidemiological data for 670 isolates of S. equi recovered from 19 different countries using a new core-genome multilocus sequence typing (cgMLST) web bioresource. Genetic relationships among all 670 S. equi isolates were determined at high resolution, revealing national and international transmission events that drive this endemic disease in horse populations throughout the world. Our data argue for the recognition of the international importance of strangles by the Office International des Épizooties to highlight the health, welfare and economic cost of this disease. The Pathogenwatch cgMLST web bioresource described herein is available for tailored genomic analysis of populations of S. equi and its close relative S. equi subspecies zooepidemicus that are recovered from horses and other animals, including humans, throughout the world. This article contains data hosted by Microreact

Species richness of drained riparian forests in the urban area of Wroclaw

Las Osobowicki forest is a remnant riparian woodland of the Odra valley, although its site conditions have been anthropogenically disturbed. To assess species richness of the drained forest, floristic data were collected from circular plots with a radius of 5.64 m. Plots were systematically distributed in forest communities. In total, 87 species were identified in the study area, with a mean of 14 species per plot. The share of alien species was minor. Flood prevention caused site drying and, as a result, decrease in species richness of the riparian forest. However, spatial distribution of species number values proves the sustained influence of the moisture factor on the vegetation. Connection of species richness and hydrological conditions is supported by positive correlation between species richness and Ellenberg moisture index