A Guide to Disability Statistics from the National Health Interview Survey

The purpose of this paper is to examine the information on the population with disabilities in a nationally representative survey conducted by the National Center on Health Statistics called the National Health Interview Survey (NHIS). The paper provides a description of the disability information available in the NHIS and how the data may be used to assess the employment, economic well being and health of the population. Descriptive statistics from the 2002 NHIS public use files are used to illustrate the type of analysis that will be useful to researchers and policymakers

The role of stereotactic radiosurgery in the multimodal management of growth hormone–secreting pituitary adenomas

Growth hormone (GH)–secreting pituitary adenomas represent a common source of GH excess in patients with acromegaly. Whereas surgical extirpation of the culprit lesion is considered first-line treatment, as many as 19% of patients develop recurrent symptoms due to regrowth of previously resected adenomatous tissue or to continued growth of the surgically inaccessible tumor. Although medical therapies that suppress GH production can be effective in the management of primary and recurrent acromegaly, these therapies are not curative, and lifelong treatment is required for hormonal control. Stereotactic radiosurgery has emerged as an effective adjunctive treatment modality, and is an appealing alternative to conventional fractionated radiation therapy. The authors reviewed the growing body of literature concerning the role of radiosurgical procedures in the treatment armamentarium of acromegaly, and identified more than 1350 patients across 45 case series. In this review, the authors report that radiosurgery offers true hormonal normalization in 17% to 82% of patients and tumor growth control in 37% to 100% of cases across all series, while minimizing adverse complications. As a result, stereotactic radiosurgery represents a safe and effective treatment option in the multimodal management of primary or recurrent acromegaly secondary to GH-secreting pituitary adenomas

Beginning Anew: Archives Education at University of Massachusetts Boston, 2010-2014

This essay discusses the creation of an M.A. Archives Track for the Department of History at the University of Massachusetts Boston in 2010-2014. After laying out the process of creating the Track, and developing its curriculum, the essay discusses the relationship between the history and archives professions. Drawing on student feedback, the essay concludes with an evaluation of history-based archival education in an era when archival education has been increasingly based in library science programs

Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig

Odontoameloblastomas (previously incorporated within ameloblastic odontomas) are matrix-producing odontogenic mixed tumors and are closely related in histologic appearance to the 2 other types of matrix-producing odontogenic mixed tumors: odontomas and ameloblastic fibro-odontomas. The presence or absence of intralesional, induced non-neoplastic tissue must be accounted for in the diagnosis. Herein we describe a naturally occurring odontoameloblastoma with extensive chondroid cementum deposition in a guinea pig (Cavia porcellus). Microscopically, the mass featured palisading neoplastic odontogenic epithelium closely apposed to ribbons and rings of a pink dental matrix (dentinoid), alongside extensive sheets and aggregates of chondroid cementum. The final diagnosis was an odontoameloblastoma given the abundance of odontogenic epithelium in association with dentinoid but a paucity of pulp ectomesenchyme. Chondroid cementum is an expected anatomical feature of cavies, and its presence within the odontoameloblastoma was interpreted as a response of the ectomesenchyme of the dental follicle to the described neoplasm. Our case illustrates the inductive capabilities of odontoameloblastomas while highlighting species-specific anatomy that has resulted in a histologic appearance unique to cavies and provides imaging and histologic data to aid diagnosis of these challenging lesions

The Impact of Shape on the Perception of Euler Diagrams

Euler diagrams are often used for visualizing data collected into sets. However, there is a significant lack of guidance regarding graphical choices for Euler diagram layout. To address this deficiency, this paper asks the question `does the shape of a closed curve affect a user's comprehension of an Euler diagram?' By empirical study, we establish that curve shape does indeed impact on understandability. Our analysis of performance data indicates that circles perform best, followed by squares, with ellipses and rectangles jointly performing worst. We conclude that, where possible, circles should be used to draw effective Euler diagrams. Further, the ability to discriminate curves from zones and the symmetry of the curve shapes is argued to be important. We utilize perceptual theory to explain these results. As a consequence of this research, improved diagram layout decisions can be made for Euler diagrams whether they are manually or automatically drawn

Beatson International Cancer Conference: invasion and metastasis

No abstract available

How optimal caseload midwifery can modify predictors for preterm birth in young women: integrated findings from a mixed methods study

Objective to identify possible mechanisms by which caseload midwifery reduces preterm birth for young childbearing women. Design a mixed methods triangulation, convergence design was used to answer the research question ‘How does the way maternity care is provided affect the health and well-being of young women and their babies?’ The project generated quantitative and qualitative findings which were collected and analysed concurrently then separately analysed and published. The research design enabled integration of the quantitative and qualitative findings for further interpretation through a critical pragmatic lens. Setting a tertiary maternity hospital in Australia providing care to approximately 500 pregnant young women (aged 21 years or less) each year. Three distinct models of care were offered: caseload midwifery, young women's clinic, and standard 'fragmented' care. Participants a cohort study included data from 1971 young women and babies during 2008–2012. An ethnographic study included analysis of focus group interviews with four caseload midwives in the young women's midwifery group practice; as well as ten pregnant and postnatal young women receiving caseload midwifery care. Findings integrated analysis of the quantitative and qualitative findings suggested particular features in the model of care which facilitated young women turning up for antenatal care (at an earlier gestation and more frequently) and buying in to the process (disclosing risks, engaging in self-care activities and accepting referrals for assistance). We conceptualised that Optimal Caseload Midwifery promotes Synergistic Health Engagement between midwife and the young woman. Key conclusions optimal Caseload Midwifery (which includes midwives with specific personal attributes and philosophical commitments, along with appropriate institutional infrastructure and support) facilitates midwives and young clients to develop trusting relationships and engage in maternity care. Health engagement can modify predictors for preterm birth that are common amongst pregnant adolescents by promoting earlier maternity booking, sufficient antenatal care, greater emotional resilience, ideal gestational weight gain, less smoking/drug use, and fewer untreated genito-urinary infections. Implications for practice the institutional infrastructure and managerial support for caseload midwifery should value and prioritise the philosophical commitments and personal attributes required to optimise the model. Furthermore the location of visits, between appointment access to primary midwife, and back-up system should be organised to optimise the midwife-woman relationship in order to promote the young woman's engagement with maternity care

Animal breeding and genetics in the Tanzania livestock master plan

Bill & Melinda Gates Foundatio