Dynamic server selection in a multithreaded network computing environment

Research has been conducted at the Iowa State University Center for Nondestructive Evaluation (CNDE) to create a structure in which existing numerical modeling programs can be converted to execute in a network computing environment. This research task is to include the development of an extensible architecture which accommodates the timely integration of new processing capabilities and requirements. The research was motivated by many needs within the CNDE to reduce the predicted run times associated with the current and future modeling programs

Ongoing educational needs of trained nurses.

The research was undertaken to ascertain the views of trained nurses on the need for ongoing professional education and the availability of such education as perceived by nurses in one Health Region. The main tool used was a questionnaire developed for the research, for which two ordinal scales were devised. Some questions were dichotomous, some open-ended and two questions contained four-point scales. The sample of 284 nurses contained respondents of two grades, Charge Nurses and Nursing Officers; and from two divisions, general nurses and midwives. These nurses were from forty-five hospitals which were situated in urban and rural areas. The hospital size varied from less than fifty beds to more than two hundred beds. The results indicated that Charge Nurses in the general divisions exhibited low levels of satisfaction with the facilities for ongoing education provided for them. Midwives, who have statutory 'refresher' courses were more satisfied than general nurses. Nursing Officers in the general divisions were more satisfied than Charge Nurses. Respondents were aware of facilities for post-basic specialist training and realistic in their perceptions of other facilities. These findings are discussed, their limitations identified and areas requiring further research identified

MLS: Airplane system modeling

Analysis, modeling, and simulations were conducted as part of a multiyear investigation of the more important airplane-system-related items of the microwave landing system (MLS). Particular emphasis was placed upon the airplane RF system, including the antenna radiation distribution, the cabling options from the antenna to the receiver, and the overall impact of the airborne system gains and losses upon the direct-path signal structure. In addition, effort was expended toward determining the impact of the MLS upon the airplane flight management system and developing the initial stages of a fast-time MLS automatic control system simulation model. Results ot these studies are presented

Institutions and policies to implement the Tanzania livestock master plan

Bill & Melinda Gates Foundatio

Understanding thermal alleviation in cold dwell fatigue in titanium alloys

Dwell fatigue facet nucleation has been investigated in isothermal rig disc spin tests and under anisothermal in-service engine conditions in titanium alloy IMI834 using α-HCP homogenised and faithful α-β lamellar microstructure crystal plasticity representations. The empirically observed facet nucleation and disc failure at low stress in the isothermal spin tests has been explained and originates from the material rate sensitivity giving rise to soft grain creep accumulation and hard grain basal stresses which increase with fatigue cycling until facet nucleation. The α-HCP homogenised model is not able to capture this observed behaviour at sensible applied stresses. In contrast to the isothermal spin tests, anisothermal in-service disc loading conditions generate soft grain slip accumulation predominantly in the first loading cycle after which no further load shedding nor soft grain creep accumulation is observed, such that the behaviour is stable, with no further increase in hard grain basal stress so that facet nucleation does not occur, as observed empirically. The thermal alleviation, which derives from in-service loading conditions and gives the insensitivity to dwell fatigue dependent on the temperature excursions, has been explained. A stress-temperature map for IMI834 alloy has been established to demarcate the ranges for which the propensity for dwell fatigue facet nucleation is high, threatening or low

Antibiotic Resistance Characteristics of Pseudomonas aeruginosa Isolated from Keratitis in Australia and India.

This study investigated genomic differences in Australian and Indian Pseudomonas aeruginosa isolates from keratitis (infection of the cornea). Overall, the Indian isolates were resistant to more antibiotics, with some of those isolates being multi-drug resistant. Acquired genes were related to resistance to fluoroquinolones, aminoglycosides, beta-lactams, macrolides, sulphonamides, and tetracycline and were more frequent in Indian (96%) than in Australian (35%) isolates (p = 0.02). Indian isolates had large numbers of gene variations (median 50,006, IQR = 26,967-50,600) compared to Australian isolates (median 26,317, IQR = 25,681-33,780). There were a larger number of mutations in the mutL and uvrD genes associated with the mismatch repair (MMR) system in Indian isolates, which may result in strains losing their efficacy for DNA repair. The number of gene variations were greater in isolates carrying MMR system genes or exoU. In the phylogenetic division, the number of core genes were similar in both groups, but Indian isolates had larger numbers of pan genes (median 6518, IQR = 6040-6935). Clones related to three different sequence types-ST308, ST316, and ST491-were found among Indian isolates. Only one clone, ST233, containing two strains was present in Australian isolates. The most striking differences between Australian and Indian isolates were carriage of exoU (that encodes a cytolytic phospholipase) in Indian isolates and exoS (that encodes for GTPase activator activity) in Australian isolates, large number of acquired resistance genes, greater changes to MMR genes, and a larger pan genome as well as increased overall genetic variation in the Indian isolates

New developments in dual cure epoxies

Direct write 3D printing provides an exciting new means of generating novel structures from thermosetting resins via an additive approach. Initial efforts along these lines demonstrated the preparation of homogenous, high quality parts. More recent work has shown that it is possible to modulate the properties of these parts locally through changes in orientation of high aspect ratio fillers. In this work, we present complementary developments related to resin chemistry that should provide practitioners of direct write 3D printing with additional options as far as the realization of functional gradations is concerned. This is accomplished via the creation of so-called “dual cure” resins. Here this term refers to materials that undergo thermal cure in a similar fashion to many conventional resins. Then, in a second step, the selective exposure of these materials to high energy radiation (gamma rays, electrons, etc.) results in further increases in local crosslink density, altering thermomechanical performance and providing a means of inducing arbitrary gradations in properties in a post-processing step. A number of different families of dual cure resins have been explored and are presented here, as well as data concerning changes in thermal and mechanical performance as a function of the details of the dual curing process. Preliminary efforts giving evidence of the generation of stable functional gradations in practice are also described. Ongoing and future efforts are focused on the optimization of these systems and the incorporation of their cure-dependent mechanical behavior into simulations in order to enable design optimization

Idiopathic hypercalciuria: Association with isolated hematuria and risk for urolithiasis in children

Idiopathic hypercalciuria: Association with isolated hematuria and risk for urolithiasis in children. A prospective multicenter study was designed to determine the frequency and prognostic importance of hypercalciuria in children with hematuria. Urinary calcium excretion was examined in 215 patients with unexplained isolated hematuria (no proteinuria, urolithiasis, infection or systemic disorder). Hypercalciuria (urinary calcium excretion > 4 mg/kg/day) was identified in 76 patients (35%). Compared to patients with normal urinary calcium excretion, children with hematuria and hypercalciuria were characterized by male preponderance, white race, family history of urolithiasis, gross hematuria and calcium oxalate crystals. Renal biopsies were performed in 10 patients with urinary calcium excretion 0.4 to 2.5 mg/kg/day; three had IgA glomerulonephritis, three had glomerular basement membrane thinning, one had proliferative glomerulonephritis and three were normal. Renal biopsies in three patients with hypercalciuria showed focal segmental glomerulosclerosis, hereditary nephritis or no abnormalities. Oral calcium loading tests showed renal hypercalciuria in 26 patients, absorptive hypercalciuria in 15 patients and were not diagnostic in 35 patients. Serum parathyroid hormone, bicarbonate and phosphorus and urinary cyclic adenosine monophosphate concentrations were similar in the three groups of hypercalciuric patients. Urinary calcium excretion after one week of dietary calcium restriction was higher (5.8 mg/kg/day) in renal hypercalciuria than in other hypercalciuric patients (3.4 mg/kg/day), P < 0.01. One to four years follow-up was available for 184 patients. Eight of 60 hypercalciuric patients developed urolithiasis or renal colic compared to 2 of 124 patients with normal urinary calcium excretion (P < 0.001). Hypercalciuria is commonly associated with isolated hematuria and represents a risk factor for future urolithiasis in children with hematuria. Oral calcium loading tests offer little diagnostic benefit over 24-hour urinary calcium excretion following dietary calcium restriction