A quality management based on the Quality Model life cycle

Managing quality is a hard and expensive task that involves the execution and control of processes and techniques. For a good quality management, it is important to know the current state and the objective to be achieved. It is essential to take into account with a Quality Model that specifies the purposes of managing quality. QuEF (Quality Evaluation Framework) is a framework to manage quality in MDWE (Model-driven Web Engineering). This paper suggests managing quality but pointing out the Quality Model life cycle. The purpose is to converge toward a quality continuous improvement by means of reducing effort and time.Ministerio de Ciencia e Innovación TIN2010-20057-C03-02Ministerio de Ciencia e Innovación TIN 2010-12312-EJunta de Andalucía TIC-578

Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases.

BACKGROUND: Emphysema is characterised by distinct pathological sub-types, but little is known about the divergent underlying aetiology. Matrix-metalloproteinases (MMPs) are proteolytic enzymes that can degrade the extracellular matrix and have been identified as potentially important in the development of emphysema. However, the relationship between MMPs and emphysema sub-type is unknown. We investigated the role of MMPs and their inhibitors in the development of emphysema sub-types by quantifying levels and determining relationships with these sub-types in mild-moderate COPD patients and ex/current smokers with preserved lung function. METHODS: Twenty-four mild-moderate COPD and 8 ex/current smokers with preserved lung function underwent high resolution CT and distinct emphysema sub-types were quantified using novel local histogram-based assessment of lung density. We analysed levels of MMPs and tissue inhibitors of MMPs (TIMPs) in bronchoalveolar lavage (BAL) and assessed their relationship with these emphysema sub-types. RESULTS: The most prevalent emphysema subtypes in COPD subjects were mild and moderate centrilobular (CLE) emphysema, while only small amounts of severe centrilobular emphysema, paraseptal emphysema (PSE) and panlobular emphysema (PLE) were present. MMP-3, and -10 associated with all emphysema sub-types other than mild CLE, while MMP-7 and -8 had associations with moderate and severe CLE and PSE. MMP-9 also had associations with moderate CLE and paraseptal emphysema. Mild CLE occurred in substantial quantities irrespective of whether airflow obstruction was present and did not show any associations with MMPs. CONCLUSION: Multiple MMPs are directly associated with emphysema sub-types identified by CT imaging, apart from mild CLE. This suggests that MMPs play a significant role in the tissue destruction seen in the more severe sub-types of emphysema, whereas early emphysematous change may be driven by a different mechanism. TRIAL REGISTRATION: Trial registration number NCT01701869

Primary isolated extramedullary plasmacytoma of the colon: a case report

The original publication is available at http://www.samj.org.zaA 10th case of extramedullary plasmacytoma (EMP) of the colon is reported. The term 'primary isolated extramedullary plasmacytoma' is preferred to those terms previously used. A broad classification of plasmacytoma of the gastrointestinal tract is suggested and a management policy, based on this classification, is outlined.Publishers' versio

Quality evaluation for Model-Driven Web Engineering methodologies

Context: There are lots of approaches or methodologies in the Model-Driven Web Engineering (MDWE) context to develop Web Applications without reaching a consensus on the use of standards and scarcity of both, practical experience and tool support. Objective: Model-Driven Web Engineering (MDWE) methodologies are constantly evolving. Moreover, Quality is a very important factor to identify within a methodology as it defines processes, techniques and artifacts to develop Web Applications. For this reason, when analyzing a methodology, it is not only necessary to evaluate quality, but also to find out how to improve it. The main goal of this paper is to develop a set of Quality Characteristics and Sub-Characteristics for MDWE approaches based on ISO/ IEC standards. Method: From the software products context, some widely standards proposed, such as ISO/IEC 9126 or ISO/IEC 25000, suggest a Quality Model for software products, although up to now, there are no standard methods to assess quality on MDWE methodologies. Such methodologies can be organized into Properties, thus, a methodology has artifacts, processes and techniques. Then, each item is evaluated through a set of appropriate Quality Characteristics, depending on its nature. This paper proposes to evaluate a methodology as a product itself. Results: This paper recommends a set of Quality Characteristics and Sub-Characteristics based on these standards in order to evaluate MDWE methodologies quality. Additionally, it defines an agile way to relate these Quality Sub-Characteristics to Properties with the sole purpose of not only analyzing, but also assessing and improving MDWE methodologies. Conclusions: The application of these Quality Characteristics and Sub-Characteristics could promote efficiency in methodologies since this kind of assessment enhances both the understanding of strengths and weaknesses of approaches.Ministerio de Educación y Ciencia TIN2007-67843-C06-03Ministerio de Educación y Ciencia TIN2010-20057-C03-0

Insensitivity of visual short-term memory to irrelevant visual information

Several authors have hypothesised that visuo-spatial working memory is functionally analogous to verbal working memory. Irrelevant background speech impairs verbal short-term memory. We investigated whether irrelevant visual information has an analogous effect on visual short-term memory, using a dynamic visual noise (DVN) technique known to disrupt visual imagery (Quinn & McConnell, 1996a). Experiment 1 replicated the effect of DVN on pegword imagery. Experiments 2 and 3 showed no effect of DVN on recall of static matrix patterns, despite a significant effect of a concurrent spatial tapping task. Experiment 4 showed no effect of DVN on encoding or maintenance of arrays of matrix patterns, despite testing memory by a recognition procedure to encourage visual rather than spatial processing. Serial position curves showed a one-item recency effect typical of visual short-term memory. Experiment 5 showed no effect of DVN on short-term recognition of Chinese characters, despite effects of visual similarity and a concurrent colour memory task that confirmed visual processing of the characters. We conclude that irrelevant visual noise does not impair visual short-term memory. Visual working memory may not be functionally analogous to verbal working memory, and different cognitive processes may underlie visual short-term memory and visual imagery

Entity reconciliation in big data sources: A systematic mapping study

The entity reconciliation (ER) problem aroused much interest as a research topic in today’s Big Dataera, full of big and open heterogeneous data sources. This problem poses when relevant information ona topic needs to be obtained using methods based on: (i) identifying records that represent the samereal world entity, and (ii) identifying those records that are similar but do not correspond to the samereal-world entity. ER is an operational intelligence process, whereby organizations can unify differentand heterogeneous data sources in order to relate possible matches of non-obvious entities. Besides, thecomplexity that the heterogeneity of data sources involves, the large number of records and differencesamong languages, for instance, must be added. This paper describes a Systematic Mapping Study (SMS) ofjournal articles, conferences and workshops published from 2010 to 2017 to solve the problem describedbefore, first trying to understand the state-of-the-art, and then identifying any gaps in current research.Eleven digital libraries were analyzed following a systematic, semiautomatic and rigorous process thathas resulted in 61 primary studies. They represent a great variety of intelligent proposals that aim tosolve ER. The conclusion obtained is that most of the research is based on the operational phase asopposed to the design phase, and most studies have been tested on real-world data sources, where a lotof them are heterogeneous, but just a few apply to industry. There is a clear trend in research techniquesbased on clustering/blocking and graphs, although the level of automation of the proposals is hardly evermentioned in the research work.Ministerio de Economía y Competitividad TIN2013-46928-C3-3-RMinisterio de Economía y Competitividad TIN2016-76956-C3-2-RMinisterio de Economía y Competitividad TIN2015-71938-RED

Overall evaluation of Skylab imagery for mapping of Latin America

The author has identified the following significant results. Skylab imagery is both desired and needed by the Latin American catographic agencies. The imagery is cost beneficial for the production of new mapping and maintenance of existing maps at national topographic series scales. If this information was available on a near time routine coverage basis, it would provide an excellent additional data base to the Latin American cartographic community, specifically Argentina, Bolivia, Chile, Colombia, Dominican Republic, Guatemala, Paraguay, and Venezuela

CEM03 and LAQGSM03 - new modeling tools for nuclear applications

An improved version of the Cascade-Exciton Model (CEM) of nuclear reactions realized in the code CEM2k and the Los Alamos version of the Quark-Gluon String Model (LAQGSM) have been developed recently at LANL to describe reactions induced by particles and nuclei for a number of applications. Our CEM2k and LAQGSM merged with the GEM2 evaporation/fission code by Furihata have predictive powers comparable to other modern codes and describe many reactions better than other codes; therefore both our codes can be used as reliable event generators in transport codes for applications. During the last year, we have made a significant improvements to the intranuclear cascade parts of CEM2k and LAQGSM, and have extended LAQGSM to describe photonuclear reactions at energies to 10 GeV and higher. We have produced in this way improved versions of our codes, CEM03.01 and LAQGSM03.01. We present a brief description of our codes and show illustrative results obtained with CEM03.01 and LAQGSM03.01 for different reactions compared with predictions by other models, as well as examples of using our codes as modeling tools for nuclear applications.Comment: 12 pages, 10 figures, to be published in Journal of Physics: Conference Series: Proc. Europhysics Conf. on New Trends in Nuclear Physics Applications and Technologies (NPDC19), Pavia, Italy, September 5-9, 200

Particulate organic carbon and nitrogen export from major Arctic rivers

Author Posting. © American Geophysical Union, 2016. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Global Biogeochemical Cycles 30 (2016): 629–643, doi:10.1002/2015GB005351.Northern rivers connect a land area of approximately 20.5 million km2 to the Arctic Ocean and surrounding seas. These rivers account for ~10% of global river discharge and transport massive quantities of dissolved and particulate materials that reflect watershed sources and impact biogeochemical cycling in the ocean. In this paper, multiyear data sets from a coordinated sampling program are used to characterize particulate organic carbon (POC) and particulate nitrogen (PN) export from the six largest rivers within the pan-Arctic watershed (Yenisey, Lena, Ob', Mackenzie, Yukon, Kolyma). Together, these rivers export an average of 3055 × 109 g of POC and 368 × 109 g of PN each year. Scaled up to the pan-Arctic watershed as a whole, fluvial export estimates increase to 5767 × 109 g and 695 × 109 g of POC and PN per year, respectively. POC export is substantially lower than dissolved organic carbon export by these rivers, whereas PN export is roughly equal to dissolved nitrogen export. Seasonal patterns in concentrations and source/composition indicators (C:N, δ13C, Δ14C, δ15N) are broadly similar among rivers, but distinct regional differences are also evident. For example, average radiocarbon ages of POC range from ~2000 (Ob') to ~5500 (Mackenzie) years before present. Rapid changes within the Arctic system as a consequence of global warming make it challenging to establish a contemporary baseline of fluvial export, but the results presented in this paper capture variability and quantify average conditions for nearly a decade at the beginning of the 21st century.National Science Foundation Grant Numbers: 0229302, 0732985; U.S. Geological Survey; Department of Indian and Northern Affairs2016-11-1