Uticaj predzimske setve na ranostasnost i prinos peršuna

On the average, there was a positive effect of pre-winter sowing on earliness of parsley (by 24 days). Parsley yield varied depending on weather conditions. Root yield was more susceptible. On the average, it amounted to 22.79 and 25.84 g/ha. The difference in favor of spring sowing amounted to 3.05 g/ha and was statistically significant. Leaf yield amounted to 3.67 and 4.38 t/ha. The difference was 0.71 t/ha and was statistically insignificant. Thus, it could be conclude that pre-winter sowing effected parsley. Especially was effected earliness. Therefore, in parsley production should be employed pre-winter sowing.U radu se govori o uticaju predzimske setve na ranostasnost i prinos peršuna Setva je obavljana kasno u jesen (novembar-decembar), tj. pred nastupanje jačih mrazeva. Kao kontrola poslužila je prolećna setva. Utvrđeno je da predzimska setva značajno povećava ranostasnost peršuna, dok se prinos smanjuje. Predzimsku setvu ipak vredi koristiti u proizvodnji peršuna (povećava se ranostasnost)

Central Retinal Artery Occlusion in a Patient with Metabolic Syndrome X

Purpose: To report a case of central retinal artery occlusion (CRAO) in a patient with metabolic syndrome X. Case Report: A 64 year-old-man presented with abrupt, painless, and severe loss of vision in his left eye. Indirect ophthalmoscopy disclosed signs compatible with CRAO and laboratory investigations revealed erythrocyte sedimentation rate of 74 mm/h, C-reactive protein (CRP) level of 21 mg/l, hyperglycemia, hyperuricemia, hypertriglyceridemia and hypercholesterolemia. Fluorescein angiography and immunological studies excluded other systemic disorders. The patient met the full criteria of the National Cholesterol Education Program for metabolic syndrome X. Conclusion: In addition to different vascular complications such as stroke, and cardiovascular disease, metabolic syndrome X may be associated with retinal vascular occlusions

Nanomolar Quantification of Polydatin at Boron Doped Diamond Electrode. Application in Dietary Supplements

In this research we demonstrated detailed electrochemistry polydatin. Polydatin is a natural compound with expressed antioxidant activity. Electrochemical behavior of polydatin was tested in the potential range from -1.5 V to 2 V at unmodified boron doped diamond electrode in various pH of supporting electrolyte. It has been noticed that polydatin provides two oxidation peaks, one at around 0.73 V and second at around 1.3 V. In the reverse scan no reduction peak was observed. Quantification of polydatin was done based on first oxidation peak using square wave voltammetry. After optimization of the method, linear working range from 1·10-7 M to 7·10-5 M was obtained, with limit of detection and limit of quantification of 6·10-9 M and 2·10-8 M, respectively. Negligible interferences effects were noticed. Developed method shows excellent accuracy and precision toward detection of polydatin. Also, developed method was used for quantification of polydatin in dietary supplements

Artificial Neural Network Model for Prediction of Students’ Success in Learning Programming

249-254The model for predicting students’ success in acquiring programming knowledge and skills is presented in this paper. In order to collect the data needed for development of the model, 159 undergraduate IT students from Faculty of Technical Sciences in Čačak were analyzed. Besides the score on programming knowledge test, the following data were also gathered for each student: high school, the subject he/she took at the entrance exam, size of student’s birthplace, average high school grade, points from high school, gender, previous education, existence of IT educational profile in high school, study year, percentage of attendance on classes, reason for enrolment, subjective assessment of preparedness for programming, solving sequential tasks, type of programming student prefers, subjective assessment of preparedness for working in industry, solving tasks with branching and cycle, solving complex tasks, knowledge level, formal education, informal education, Kolb's learning style. In order to predict students’ success in learning programming multilayer perceptron was used with backpropagation learning algorithm. The cross-validation methodology was used for the training and testing of the classifiers. Transformation process is performed on the points students achieved on the test in order to get three categories related to success. Based on the results about the relevance of the parameters, the model reached an accuracy of 92.3%. In order to facilitate the use of the model, a Web-based application for displaying the results was created. It is primarily intended for teachers with no experience in working with neural networks, who can use it for planning the teaching

Superficial urinary bladder tumors treatment results: A 10-year experience

Background/Aim. The most common urinary bladder tumors are superficial tumors. Due to their tension to relapse and progress towards deeper layers after surgical therapy, an adequate therapy significantly contributed to the improvement of the results of urinary bladder tumors treatment. Staging and gradus of the tumor, presence of the carcinoma in situ (CIS) or relapses significantly influenced the choice of the therapy. The aim of this study was to ascertain the effectiveness of the intravesicelly applied BCG (Bacille Colmette - Guerin) vaccine or chemiotherapy in the prevention of the relapses and further progression of superficial urinary bladder tumors. Methods. All of the diagnosed superficial tumors of bladder were removed by transurethral resection (TUR). After receiving the patohistological finding they were subjected to adjuvant therapy, immune BCG vaccine or chemiotherapy (epirubicin, doxorubicin, mitomycin-C). The third group did not accept adjuvant therapy, but had regularly scheduled cystoscopic controls. The appearance of relapses, progression of stage and grades of the tumor, as well as possible unwanted effects of adjuvant therapy were registered. Results. The applied immunotherapy (BCG) influenced decreased tumor relapses (7%) and statistically important difference between patients who had taken adjuvant chemotherapy (relapses 18.4%) and those without this therapy was acknowledged. Grades of tumor did not show statistically significant difference on tumor relapse. A significantly longer period of time in the appearance of tumor relapse after BCG (29.33 months), had significant importance comparing to chemio (9.44 months) or non-taken adjuvant therapy (9.84 months). Very small number of unwanted effects suggested an obligatory undertaking adjuvant therapy after TUR of superficial tumors. Conclusion. A significant decrease of relapses as well as avoidance of further progression of urinary bladder tumors, has introduced adjuvant therapy in all of the protocols, while the dosing scheme is not unique yet due to trying to find the optimal dose, the length of application and possible dose maintenance.

Screen printed diamond electrode as efficient “point-of-care” platform for submicromolar determination of cytostatic drug in biological fluids and pharmaceutical product

This work presents advanced electrochemical platform based on screen printed diamond electrode (SPDE) system for the single drop “point-of-care” testing. Proposed approach was applied for the quantification of doxorubicin hydrochloride (DOX) in biological fluids and pharmaceutical product. Using a single drop (~30 μL) of the tested solution at the electrode surface, DOX showed high electroactivity over a wide range of pHs. In these conditions, single oval shaped, well-defined and pH dependent oxidation peak was observed in the potential range from 0.5 V to 1.3 V. In the reverse scan, two cathodic peaks, were noted – around 0.3 V and – 0.5 V. Similarly, first reduction peak was pH dependent, while second one was independent in the studied range. Experimental conditions for DOX quantification were optimized and natures of the electrode reactions were investigated. Working linear range obtained for DOX detection was from 0.1 to 2.5 μM. Diffusion controlled electrode reaction reveal long life time of the proposed electrode as well high potential for practical application. Developed procedure was successfully applied for the DOX analysis in biological fluids – urine and pharmaceutical formulation. Obtained results clearly indicated that given procedure can be easily implemented for pharmaceutical control and medical analysis, in both, laboratory and field conditions

Zinc concentration in woody and herbaceous plants at Kosmaj area, Serbia

In the paper, the content of heavy metal (Zn) in plants of Kosmaj area was analyzed. Concentration of Zn was measured at four locations, in vegetative parts - leaves of ten plants (eight of them were woody plants and the other two were herbaceous plants). Results showed that samples of plant material from all locations are not contaminated with heavy metal and, at the same time, the results show lack of Zn at some locations, as well. It is important to emphasize that Zn does not endanger the area of Kosmaj

MOTORIČKE SPOSOBNOSTI RUKOMETAŠA RAZLIČITE BIOLOŠKE ZRELOSTI

The aim of this research was to determine the differences between the results from the tests of motor abilities carried out on a selected group of handball players in relation to their biological maturation. A total of 23 handball players, belonging to a selected group, took part in this research. The overall sample of participants was divided into three groups based on their biological maturation. The measurements of motor abilities were carried out using the following tests: explosive power, sprint speed and rapid changes in direction. The statistical analysis included descriptive statistics, a univariate analysis of variance and the Bonferroni PostHoc test in order to determine whether a statistically significant difference could be detected between the groups on the tests of motor abilities. Based on the statistical analysis (ANOVA method), a difference was determined between the peak height velocity (PHV) groups for all the variables. The PostHoc test later determined that there were no differences for any of the variables between the PrePHV and MidPHV groups. Differences in all the variables were determined between the PrePHV and PostPHV groups. Differences between the MidPHV and PostPHV groups were determined for 7 variables, while no statistically significant difference was determined for 3 of the variables (5JT, T-test and the Slalom). The main contribution of this research is that it indicates to coaches the inevitability of being familiar with the biological maturation of their players for optimal selection, for adequate training design, and a decrease in the risk of injury. Cilj ovog istraživanja je da se utvrde razlike u ostvarenim rezultatima u testovima motoričkih sposobnosti rukometаša jedne selekcione grupe u odnosu na biološku zrelost. Ukupno 23 rukometaša, jedne selekcione grupe, učestvovalo je u ovom istraživanju. Celokupan uzorak ispitanika podeljen je u tri gupe prema biološkoj zrelosti. Merenje motoričkih sposobnosti rađeno je testovima: eksplozivne snage, sprinta i brze promene pravca. Statistička analiza obuhvatila je deskriptivnu statistiku, univarijantnu analizu varijanse i Bonferoni PostHoc kako bi se utvrdilo između kojih grupa postoji statistički zanačajna razlika u testovima motoričkih sposobnosti. Na osnovu statističke analize (ANOVA) utvrđeno je da postoje razlike između PHV grupa u svim varijablama. PostHoc testom je naknadno utvrđeno da razlike ne postoje ni u jednoj varijabli kada se porede PrePHV i MidPHV grupe. Poređenjem PrePHV i PostPHV grupe utvrđeno je da razlike postoje u svim varijablama. Razlike između MidPHV i PostPHV grupa pronađene su u 7 varijabli, dok u 3 varijable (5JT, T-test i Slalom) ne postoji statistički značajna razlika. Glavni doprinos ovog istraživanja je što ukazuje trenerima na neminovnost poznavanja biološke zrelosti igrača kako bi izvršili optimalnu selekciju, odradili adekvatnu postavku treninga i smanjili opasnost od eventualnog povređivanja

Locally advanced cervical cancer: Preliminary results of the prospective randomized study

Background: The aim of this study is to show preliminary results of the randomized study that has been conducted among patients with advanced cervical cancer managed by loco-regional radiotherapy alone or combined treatment (radiotherapy with chemotherapy as radiosensitiser). Methods: From the beginning of 2002 till today 182 patients with locally advanced cervical cancer have been enrolled in the study (FIGO IIb-IVa). They have been treated by combined external beam irradiation (46Gy/22fr) and HDR brachyterapy (5x7Gy/A). Eighty-nine of them underwent the same radiotherapy regime with concomitant chemotherapy cisplatin (CDDP) 40mg per week). Median age for both groups were 52 years. Pathological examination showed: Squamous cell carcinoma in most cases 175, adeno Ca 6 and others 1. Effect of the therapy and early irradiation complications have been estimated by the tumor regression and toxicity grade. Results: Tumor regression have been occurred as complete response in 10.1% for RT group and for RT-HT group in 16.86%. Partial regression was for RT group 86% and for RT-HT group 87%. Early complications (haematological, urological and intestinal) in RT group were noted in 34% and in RT-HT group in 43% of patients. Conclusion: There was no benefit of RT-HT comparing to RT alone in the tumor regression of locally advanced cervical cancer. Early complications of combined therapy are more experienced than in RT group

PERCUTANEOUS NEPHROSTOMY AND DOUBLE PIGTAIL (JJ) URETERAL STENTS AS TEMPORARY METHODS IN SOLVING SUPRAVESICAL OBSTRUCTION CAUSED BY STONE

Percutaneous nephrostomy and ureteral stenting are temporary treatments for the upper urinary tract obstruction. The aim of this study was to evaluate the efficacy of these two methods by comparing complications, placement success, urinary symptoms, urine culture analyses prior to derivation placement and derivation removal and success of stone elimination after extracorporeal shock wave lithotripsy (ESWL). This prospective study included 157 patients with supravesical obstruction caused by ureteral stones. Eighty-one patients underwent percutaneus nephrostomy, and JJ stent was inserted in seventy-six (76) patients. After resolving the obstruction, ESWL was performed in all patients. There were no statistically significant differences in success of the urinary derivation placement, the urine culture results before and after placement and success of ESWL treatment between the two studied groups (p>0.05). Urinary symptoms (dysuria, hematuria, urinary urgency, frequent urination during the day) were significantly more present in patients with a JJ stent and this difference was statistically significant for each symptom (p<0.001). Major complications were verified in 2 (2.46%) patients with PCN catheter, and in 7 (9.2%) patients in the group with the JJ stent. Minor complications were significantly more frequent in the group with the JJ stent compared to the group with PCN catheter (28.39% vs 60.52%, p<0.001). Percutaneous nephrostomy and JJ stenting are optimal methods for temporary treatment of supravesical obstruction caused by ureteral stones, with similar incidence of the following complications, except for the pain, which dominates in patients with the JJ stent. Urinary symptoms and asymptomatic bacteriuria are more common in patients with the JJ stent. If the ESWL treatment of ureteral stone is performed after urinary derivation placement, we can expect greater success in patients with the JJ stent