Participation in a Full Service School After Hours Enrichment Program: An Assessment of Students\u27 Academic and Social Progress

Full service school programs are developed to address the unmet social, academic, medical, and economic needs of the students and communities they serve. Even though two schools may both be considered full service , they can still look very different in practice, depending on the specific needs of the community. Although the idea of full service community schools has existed for over a century (Dryfoos, Quinn, & Barkin, 2005), the empirical research base is scant. This study addresses the academically related domains outlined by Kronick (2005): attendance and tardiness, and academic grades. An experimental group and a control group were used. A repeated measures ANOVA was conducted on the math and reading grade data. A Mann-Whitney U test was conducted on the attendance and tardiness data. It was found that after receiving the treatment the experimental group had statistically significantly higher reading grades than the control group. Math grades were higher in the experimental group then in the control group, post-treatment. No significant between-group differences were found with either the attendance or the tardiness data. Implications, limitations and suggestions for future research are discussed

Neurospora mating type symbol mt revised to mat

After discussion with members of the Neurospora genetics community, we propose to revise the symbol designating the mating type locus from mt to mat

Negócio dos escravos : o comércio de cativos entre a Costa da Mina e a Capitania de Pernambuco (1701-1759)

Orientador: Luiz Geraldo SilvaDissertaçao (mestrado) - Universidade Federal do Paraná, Setor de Ciencias Humanas, Letras e Artes, Programa de Pós-Graduaçao em História. Defesa: Curitiba, 22/08/2008Inclui bibliografi

MapToGenome: A Comparative Genomic Tool that Aligns Transcript Maps to Sequenced Genomes

Efforts to generate whole genome assemblies and dense genetic maps have provided a wealth of gene positional information for several vertebrate species. Comparing the relative location of orthologous genes among these genomes provides perspective on genome evolution and can aid in translating genetic information between distantly related organisms. However, large-scale comparisons between genetic maps and genome assemblies can prove challenging because genetic markers are commonly derived from transcribed sequences that are incompletely and variably annotated. We developed the program MapToGenome as a tool for comparing transcript maps and genome assemblies. MapToGenome processes sequence alignments between mapped transcripts and whole genome sequence while accounting for the presence of intronic sequences, and assigns orthology based on user-defined parameters. To illustrate the utility of this program, we used MapToGenome to process alignments between vertebrate genetic maps and genome assemblies 1) self/self alignments for maps and assemblies of the rat and zebrafish genome; 2) alignments between vertebrate transcript maps (rat, salamander, zebrafish, and medaka) and the chicken genome; and 3) alignments of the medaka and zebrafish maps to the pufferfish (Tetraodon nigroviridis) genome. Our results show that map-genome alignments can be improved by combining alignments across presumptive intron breaks and ignoring alignments for simple sequence length polymorphism (SSLP) marker sequences. Comparisons between vertebrate maps and genomes reveal broad patterns of conservation among vertebrate genomes and the differential effects of genome rearrangement over time and across lineages

Developmental intervention with CBD on BDNF levels and prosocial behavior in a mouse model of autism spectrum disorder

Cannabis-based medicines have emerged as a promising therapeutic for a variety of neuropsychiatric disorders, including autism spectrum disorder (ASD). This manuscript encompasses research investigating the application of the phytocannabinoid cannabidiol (CBD) in treating core symptoms of ASD. Chapter one includes a literature review of the neurodevelopmental etiology and current pharmacological strategies for ASD. The second chapter is a paper illustrating the prosocial effects of CBD and cannabis-inspired terpenes in our mouse model of ASD. The third chapter is a pilot study looking into the developmental pathology and adolescent exposure to CBD as an interventional strategy in our preclinical model. This work and continued research can inform cannabis-based treatments for ASD in the effort to improve quality of life and offer wider accessibility to medications for affected individuals

Developmental intervention with CBD on BDNF levels and prosocial behavior in a mouse model of autism spectrum disorder

Cannabis-based medicines have emerged as a promising therapeutic for a variety of neuropsychiatric disorders, including autism spectrum disorder (ASD). This manuscript encompasses research investigating the application of the phytocannabinoid cannabidiol (CBD) in treating core symptoms of ASD. Chapter one includes a literature review of the neurodevelopmental etiology and current pharmacological strategies for ASD. The second chapter is a paper illustrating the prosocial effects of CBD and cannabis-inspired terpenes in our mouse model of ASD. The third chapter is a pilot study looking into the developmental pathology and adolescent exposure to CBD as an interventional strategy in our preclinical model. This work and continued research can inform cannabis-based treatments for ASD in the effort to improve quality of life and offer wider accessibility to medications for affected individuals