A comparative study of vaginal delivery and caesarean section in antepartum eclampsia at and beyond 34 weeks of gestation

Background: This study was done to compare maternal and fetal outcome in pregnancies after 34 weeks gestation complicated by antepartum eclampsia when terminated by caesarean section and by vaginal delivery. Methods: A comparative prospective study was done on 100 pregnant women with antepartum eclampsia at or beyond 34 weeks of gestational age from November 2019 to June 2021 at Gandhi Hospital, Secunderabad, Telangana. The patients were divided into two groups: CD group (who delivered by caesarean section) and VD group (who delivered by vaginal route). After history taking and examination, delivery was planned according to the gestational age, foetal condition and Bishop’s score. The associated indication for caesarean, induction delivery interval in vaginal deliveries, total blood loss was noted. Baby details were noted and were followed till discharge at hospital. Results: The incidence of caesarean section was 41% and that of vaginal delivery was 59%. Highest incidence of antepartum eclampsia was seen in the age group of 20-24 years and between 37-40 weeks. Most common indication of caesarean section was fetal distress (19%). The convulsion-delivery interval was less in CD group and it was statistically significant (p value 0.01). The incidence of live births, still births and IUD was better in the CD group than VD group (p value 0.02). Perinatal mortality was more in vaginal delivery group (27.64%) than in caesarean section group (12.19%). Maternal mortality was 1.7% in the VD group and nil in the CD group. Conclusions: The study reflected that both perinatal and maternal morbidity and mortality were found to be lesser in the CD group in comparison with the VD group. Thus, early decision for caesarean section especially when delivery is not anticipated within 6 hours of admission is essential in improving the perinatal and maternal outcome in eclampsia

QUERY PARADIGM TO EXTRACT MOST RELEVANT OBJECTS BY GIVEN SET OF TAGS

Nonetheless, in lots of application scenarios, users cannot precisely formulate their keywords and rather choose to choose them from some candidate keyword sets. Existing studies mainly focus regarding how to efficiently discover the top-k result set given a spatio-textual query. Spatio-textual queries retrieve probably the most similar objects regarding confirmed location along with a keyword set. Driven by these applications, we advise a manuscript query paradigm, namely reverse keyword look for spatio-textual top-k queries (RST Q). Furthermore, in information browsing applications, it's helpful to focus on the objects using the tags to which the objects have higher rankings. It returns the keywords to which a target object is a spatio-textual top-k result. Extensive experimental evaluation demonstrates the efficiency in our suggested query techniques when it comes to both computational cost and that to cost. By being able to access our prime-level nodes of KcR-tree, we are able to estimate the rankings from the target object without being able to access the particular objects. To efficiently process the brand new query, we devise a manuscript hybrid index KcR-tree to keep and summarize the spatial and textual information of objects

DISCOVERY OF ONLINE PUBLIC ATTITUDE FOR HACKED SYSTEMS

In order to better serve users social networking needs, OSNs provides a wide range of Internet features for users to share, for example, creating contacts, delivering messages, uploading photos, browsing the latest updates from friends, etc. In order to verify the strength of a social behavior profile when an account activity abnormality is detected, we use the social behavior file for each user to distinguish between their user's own user clicks and transfers to all other users. We investigate the representation of social behaviors of people's users to identify anomalies in the use of the account. Many activities in the OSN require multiple steps to achieve them. Model national statistical organizations classify social information into different types of pages. The time a person needs to complete each of the activities given is greatly influenced by the user's social characteristics. We provide aggregate measurement results for each behavioral function for users to display the valuable space. Finally, we use an example as an example of diversity in user behavior. We also process each sequence of clicks before performing a detailed analysis of the measurement. Mix verification can be used to ensure that each piece of data can be used for both training and validation, and it makes sense not to be biased. We conducted three sets of experiments for different sizes of training data, the quality of the feature and the completeness of the profile, in turn, to judge their impact on the accuracy of recognition. We adjust the number of model activities to understand whether vector quality affects the accuracy of the recognition. The more the type of activity a person performs, the greater the behavior profile. The distribution properties values ​​for individual user records include a profile of their behavior

PYODERMA GANGRENOSUM SECONDARY TO TAKAYASU'S ARTERITIS

Pyoderma gangrenosum (PG) is an uncommon & noninfectious neutrophilic dermatosis commonly associated with underlying systemic disease in more than 50% of cases. About 20-30% of cases are commenced and aggravated by minor trauma or surgery, a phenomenon named pathergy. PG is associated with many systemic diseases, but association with Takayasu's arteritis (TA) / pulseless disease, which is chronic inflammatory and stenotic disease of large sized arteries is less common. These conditions responded well with systemic corticosteroids. The association of PG with TA has been less reported in the literature so far. KEYWORDS: Pyoderma gangrenosum; Takayasu's arteritis;Pulseless disease

A STUDY ON EVALUATION OF POTASSIUM ABNORMALITIES IN A TERTIARY CARE HOSPITAL

Objective: To study the occurrence, causes, predisposing factors and management of potassium abnormalities in a tertiary care hospital. Methods: Inour studywhich was for aduration of six months, we recorded patient demographics, electrolyte levels, complete blood picture, liver function tests, renal parameters, comorbid conditions,medication reconciliation and electro cardio gram (ECG) changes. The data was analyzed to find out the cause for potassium abnormality and was categorize based on their severity. Results:A total of 200 cases of potassium abnormalities was normalized during the study period. We observed158(80%)cases with hypokalemia, 37 (17%) cases with hyperkalemia and 5 (3%) caseswith subsequentPotassium abnormalities. We observed the majority of hypokalemiaarewith disease induced 87(55.06%) cases and 118 (74.0%)cases were with mild hypokalemia. Syruppotassium chloride was usedto normalize the serum potassium levels. Majority of the hyperkalemia cases were disease induced and was found in 19(51.35%)cases and 22 (59.45%) casescome under mild categorywhich was managed with injection calciumgluconate. Conclusion: Hypokalemia was the most common potassium abnormality seen in hospitalized patients.Disease inducedpotassium abnormalitieswas found to be more common in both hypo and hyperkalemia. The potassium levels were normalized with no major negative outcomes. Continuous monitoring of electrolyte levels is required for the patient to prevent further complications

Design and Fabrication of Garlic Peeler

Garlic is an important and economical plant. It has many uses in medicinal, culinary and ayurvedic purposes. Garlic peeling is a tedious, time consuming and laborious work. So far, traditional peeling methods are used for garlic peeling. These methods are observed to be unhygienic, laborious and caused high damage to garlic segments. Mechanical peelers available are costly and not affordable to small scale industries. Since, the traditional methods are laborious and mechanical methods are costly there is a need to develop low cost, mechanical peeler that will reduce the drudgery. Angular iron and flat iron was used for main frame and supporting the main units. A food grade rubber and mild steel pipe was used for rubber roller. Iron bar was used for shaft. A wire mesh was used as screen. Dimensions of garlic segments were measured using digital vernier callipers and weight of each garlic segment was measured using electronic balance. Moisture content, orthogonal dimensions, weight, geometric mean diameter, sphericity, equivalent mean diameter, shape factor, terminal velocity and drag coefficient of garlic segments were found. Moisture content of garlic segments was 59.36±0.87% (w.b). At this moisture content, average length, width and thickness of garlic segments were found to be 25.818 3.743 mm, 10.116 2.209 mm and 7.34 1.638 mm, respectively. Average weight of individual garlic segments were found to be 1.159 g. Geometric mean diameter, sphericity, equivalent mean diameter and shape factor of garlic segments were found out to be 12.422 mm, 0.481, 13.03 mm and 0.218, respectively. The terminal velocity and drag coefficient were 18.941 m/s and 0.416 at moisture content of 59.08 ± 0.82% (w.b.). Cost of peeler was estimated to be about ₹ 10,005/-

DUS characterization of rice (Oryza sativa L.) germplsm

Thirty six traditional rice cultivars conserved in germplasm collection of Regional Agricultural Research Station, Nandyal, Acharya N. G. Ranga Agricultural University were characterized for 23 qualitative and six quantitative characters following the Distinctiveness, Uniformity and Stability (DUS) descriptors, as per PPV & FRA, 2007 during kharif 2020. Out of 29 characters studied five characteristics were found monophormic, ten were dimorphic, five were of trimorphic, seven were tetramorphic and decorticated grain shape recorded five states of expression. This study will be useful for farmers for identification of varieties and researchers for selecting desirable genotypes for breeding programmes and also to register varieties under PPV & FR Act of 2001. Hybridization between parents selected from cluster III and cluster IV followed by cluster I and cluster IV and cluster II and cluster IV with the importance to traits like stem length, test weight and decorticated grain length in segregating populations can be suggested for development of better varieties from this 36 genotypes

Bioavailability enhancement of sulpiride by self-microemulsifying drug delivery system

The self-microemulsifying drug delivery system (SMEDDS) was employed to improve the bioavailability of sulpiride, a drug which is poorly soluble. The mean droplet size and emulsification time of the test formulation used for in vivo study were 9.27 ± 2.02 nm and 87 ± 5 s, respectively. When compared with Reference (Dogmatil®), the test formulation exhibited faster in-vitro drug release rate. The Cmax and AUC values of the test formulation were significantly higher than those of Reference, with an enhancement of 210.64% in the extent of absorption in rabbits. In conclusion, SMEDDS could be a potential drug delivery system to enhance the bioavailability of sulpiride.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Central giant cell reparative granuloma of the maxilla in a 5-year-old child- A case Report

Central Giant Reparative Granuloma is a non-neoplastic lesion that most commonly affects the mandible and is uncommon in children. This case-report detailed the clinical features, diagnosis, treatment, and recall of a 5-year-old boy. The oral lesion is erythematous and consists of a 4x3 cm well-demarcated swelling on the anterior maxilla that extends across the midline and covers the entire length of the palate till the junction of the hard and soft palate. Upon radiographic and histologic investigation, it was conclusive of Central giant cell reparative granuloma (CGCG). The treatment comprised of a conservative approach that included excision of the lesion, thereby reducing the risk of tooth and bone loss

A multi-ethnic genome-wide association study implicates collagen matrix integrity and cell differentiation pathways in keratoconus

Keratoconus is characterised by reduced rigidity of the cornea with distortion and focal thinning that causes blurred vision, however, the pathogenetic mechanisms are unknown. It can lead to severe visual morbidity in children and young adults and is a common indication for corneal transplantation worldwide. Here we report the first large scale genome-wide association study of keratoconus including 4,669 cases and 116,547 controls. We have identified significant association with 36 genomic loci that, for the first time, implicate both dysregulation of corneal collagen matrix integrity and cell differentiation pathways as primary disease-causing mechanisms. The results also suggest pleiotropy, with some disease mechanisms shared with other corneal diseases, such as Fuchs endothelial corneal dystrophy. The common variants associated with keratoconus explain 12.5% of the genetic variance, which shows potential for the future development of a diagnostic test to detect susceptibility to disease