Analysis of Intelligent Classifiers and Enhancing the Detection Accuracy for Intrusion Detection System

In this paper we discuss and analyze some of the intelligent classifiers which allows for automatic detection and classification of networks attacks for any intrusion detection system. We will proceed initially with their analysis using the WEKA software to work with the classifiers on a well-known IDS (Intrusion Detection Systems) dataset like NSL-KDD dataset. The NSL-KDD dataset of network attacks was created in a military network by MIT Lincoln Labs. Then we will discuss and experiment some of the hybrid AI (Artificial Intelligence) classifiers that can be used for IDS, and finally we developed a Java software with three most efficient classifiers and compared it with other options. The outputs would show the detection accuracy and efficiency of the single and combined classifiers used

A convenient synthesis of Nabumetone-An anti-inflammatory drug candidate

207-208A facile and industrially viable approach to Nabumetone (an anti-inflammatory agent) is reported

Optimization of Die-Sinking EDM Process Parameters in Machining OF AMMC-Desirability Approach

International audienceMetal Matrix Composites (MMCs) are one of the recent advanced materials having the properties of light weight, high specific strength and high wear resistance which are essential in Aircraft fittings, gears and shafts, missile parts, regulating valve parts, aerospace and defence applications. In the present work, Orthogonal Array L27 Taguchi Experimental design is prepared using Minitab software by considering material parameters: type of the base material (Al5052, Al6082, Al7075), type of reinforcement material (FlyAsh, SiC,Al2O3), percentage of the reinforcement(2. 5, 5%, 10%) and machining parameters current (Ip), pulse on time (Ton), pulse off time (Toff), tool lifting time(TL). AMMC samples are fabricated using stir casting process and experiments have been performed on these samples by using electro discharge machining(EDM) as per Taguchi design of experiments and the responses such as Material removal rate (MRR), surface roughness (SR), and Electrode wear rate (EWR) and cost are measured. The experimental response data of electro discharge machining process is analysed and the optimal combinations of influential parameters are determined using Desirability Function Analysis. Based on these optimum parameters combinations conformation test has been carried out and predicted results have been found to be in good agreement with experimental findingshardness, toughness, and good thermal resistance properties as compared to unreinforced alloys

Synthesis of 2-anilinopyridyl-triazole conjugates as antimitotic agents

A series of 2-anilinopyridyl-triazole conjugates (6a-t) were prepared and evaluated for their cytotoxic activity against a panel of three human cancer cell lines. Among them compounds 6q, 6r and 6s showed significant cytotoxic activity with IC50 values ranging from 0.1 to 4.1 mu M. Structure-activity relationships were elucidated with various substitutions on these conjugates. Flow cytometric analysis revealed that these compounds arrest the cell cycle at the G2/M phase and induce cell death by apoptosis. The tubulin polymerization assay and immunofluorescence analysis showed that these compounds (6q, 6r and 6s) effectively inhibited the microtubule assembly in human prostate cancer cells (DU-145). The docking studies showed that 6s interacts and binds efficiently with the tubulin protein at the colchicine binding site. This was further confirmed by the colchicine competitive binding assay. Moreover, compounds 6q, 6r and 6s possess anti-tubulin activity both in vitro and within cells as demonstrated by the ratio of soluble versus polymerized tubulin. Further the apoptotic effects of compounds were confirmed by Hoechst staining, caspase 3 activation, annexin-V FITC, mitochondrial membrane potential and DNA fragmentation analysis. Interestingly, these compounds did not affect the normal human embryonic kidney cells, HEK-293

Improving The Scalability And Efficiency Of K-Medoids By Map Reduce

Day to day the size of data increased enormously. Big Data concerns large-volume, complex, growing data sets with multiple, autonomous sources. With the fast development of networking, data storage, and the data collection capacity. Big Data is now rapidly expanding in all science and engineering domains, including physical, biological and bio-medical sciences. Mining knowledge from the large amount of data is a challengeable task. Map Reduce is a programming model and an associated implementation for processing and generating large data sets. Map reduce is one of the technique to achieve parallelism. map function that processes a key/value pair to generate a set of intermediate key/value pairs, and a reduce function that merges all intermediate values associated with the same intermediate key . Programs written in this functional style are automatically parallelized and executed on a large cluster of commodity machines. The run-time system takes care of the details of partitioning the input data, scheduling the programs execution across a set of machines, handling machine failures, and managing the required inter-machine communication. This allows programmers without any experience with parallel and distributed systems to easily utilize the resources of a large distributed system. In the perspective of clustering, grouping of similar of objects from big data is a challengeable task .In order to deal with the problem many researchers try to design different parallel clustering algorithms. In this paper, we propose a parallel K-Medoids clustering algorithm to improve scalability without noise and efficiency based on Map Reduce

Simplified active array L-band radar for atmospheric wind profiling: initial results

A simple approach is presented to implement an active aperture radar with a constrained beam-forming network that is adequate enough to generate multiple beams for atmospheric wind profiling. In this approach, elements of the antenna array are fed directly by dedicated transceiver modules, which are realized with commercially available communication components, making them low cost. A passive 2D beam-forming network distributes the exciter output signal and feeds the transceivers with appropriate phase distribution to generate different beams. This configuration, which is a simplified active array, eliminates the feed loss and achieves the best signal-to-noise ratio (SNR), thereby increases range coverage. Consequently, this scheme allows for a smaller antenna size when compared to a conventional passive array system, for the given range performance, and makes the wind profiler compact and transportable. A 1280-MHz, 64-element simplified active array radar has been developed, successfully validated, and is being operated at Gadanki, a tropical station in south India. Measured winds are in good agreement with those obtained with a collocated GPS sonde technique. This paper presents the configuration and sample results of the system

Ionic liquid accelerated intramolecular hetero-Diels-Alder reactions: a protocol for the synthesis of octahydroacridines

2-Azadienes derived in situ from arylamines and (R)-(+)-citronellal/3-methylcitronellal undergo intramolecular [4+2] hetero-Diels-Alder reactions in the air and moisture stable ionic liquid [bmim]BF4 in the absence of any acid catalyst to afford 1,2,3,4,4a,9,9a,10-octahydroacridine derivatives in high to quantitative yields

A One-Pot Azido Reductive Tandem Mono-N-Alkylation Employing Dialkylboron Triflates: Online ESI-MS Mechanistic Investigation

Santos, LS (Santos, Leonardo S.)Univ Talca, Chem Inst Nat Resources, Lab Asymmetr Synth, Talca, ChileAn efficient one-pot reductive tandem mono-N-alkylation of both aromatic and aliphatic azides using diallcylboron triflates as allcylating agents has been examined under standardized reaction conditions. This methodology after optimization has been employed toward the syntheses of various secondary alkyl as well as aryl amines, including the synthesis of N10-butylated pyrrolo [2,1-c] [1,4]benzodiazepine-5,11-diones via in situ azido reductive-cydization process. This protocol is particularly attractive to provide an environmentally benign and practical method for mono-N-alkylation from organic azides without the use of toxic catalysts or corrosive alkylating agents. In addition, the mechanistic aspects have been investigated and the intermediates associated with this selective transformation have been intercepted and characterized by online monitoring of the reaction by ESI-MS/MS