41 research outputs found

    FIREFOX ADD-ON FOR METAMORPHIC JAVASCRIPT MALWARE DETECTION

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    With the increasing use of the Internet, malicious software has more frequently been designed to take control of users computers for illicit purposes. Cybercriminals are putting a lot of efforts to make malware difficult to detect. In this study, we demonstrate how the metamorphic JavaScript malware can effect a victim’s machine using a malicious or compromised Firefox add-on. Following the same methodology, we develop another add-on with malware static detection technique to detect metamorphic JavaScript malware

    Strain Response in Osteocyte Lacuna Due to Mechanical Loading - a Parametric Finite Element Study Using FEBio

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    Title from PDF of title page, viewed April 18, 2017Thesis advisor: Ganesh ThiagarajanVitaIncludes bibliographical references (page 62)Thesis (M.S.)--School of Computing and Engineering. University of Missouri--Kansas City, 2016Osteocytes are the major type of living cells in bone and are known to be responsible for the biomechanosensory functions within the bone matrix. Osteocytes are activated by mechanical forces and regulates both osteoclasts and osteoblasts for bone resorption/formation. Not all the osteocytes are activated due to the applied mechanical loading because of many factors such as variation in size, position and orientation of them with respect to the loading surface. Strain response of osteocyte to the applied loading is of importance in estimating the bone resorption/formation. Although previously there were many studies that investigated strain responses at the osteocyte lacuna, very few were finite element studies and were limited to 2-dimensional models. Here in this study, a finite element model was created using FEBio at the microscale level and osteocyte lacunar and perilacunar responses were calculated based on three studies: 1) variation in lacunar position, 2) variation in lacunar orientation and 3) variation in lacunar size. A parametric study was performed by varying the elastic modulus of the perilacunar matrix which resulted in a decrease of maximum strain in lacuna with an increase in perilacunar modulus from 5GPa to 20GPa. Then, the model was scaled down to nanometer range and the lacunar responses were investigated and the results were compared with a previous study. Finally, a 3-dimensional osteocyte model was developed using MIMICS and 3-Matic softwares using confocal image stack of mouse femurs.Introduction -- Software description -- Material and methods -- Parametric analysis -- Results and discussions -- Discussions -- Conclusion and future work -- Appendix A. Step-by-step procedure in the analysi

    Quasi Switched Capacitor based integrated Boost Series Parallel Fly-back Converter for energy Storage Applications

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    711-715A quasi-Switched Capacitor technique (QSC) is used to control the switch in Interconnected Boost Series Parallel Fly-Back Converter (IBSPFC). The QSC based IBSPFC does not require any snubber circuits for all the MOSFET switches presented at primary and secondary side and power can also be transferred even if one the winding gets damage. The primary side winding of the fly-back transformer is coupled in series across with bulk capacitor to minimize switch voltage stress and the secondary winding of the 1:1 fly-back transformer is coupled with dc voltage source, three switches and capacitor which forms a Quasi switched capacitor technique. Working techniques of quasi-switched capacitor with IBSPFC have been introduced. A 75v input, 100v output and DC-DC isolated Converter switching at frequency of 100 kHz is modeled using FPGA SPARTAN6LX9 and experimental results have been presented

    A Review on Software Performance Analysis for Early Detection of Latent Faults in Design Models

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    Organizations and society could face major breakdown if IT strategies do not comply with performance requirements. This is more so in the era of globalization and emergence of technologies caused more issues. Software design models might have latent and potential issues that affect performance of software. Often performance is the neglected area in the industry. Identifying performance issues in the design phase can save time, money and effort. Software engineers need to know the performance requirements so as to ensure quality software to be developed. Software performance engineering a quantitative approach for building software systems that can meet performance requirements. There are many design models based on UML, Petri Nets and Product-Forms. These models can be used to derive performance models that make use of LQN, MSC, QNM and so on. The design models are to be mapped to performance models in order to predict performance of system early and render valuable feedback for improving quality of the system. Due to emerging distributed technologies such as EJB, CORBA, DCOM and SOA applications became very complex with collaboration with other software. The component based software systems, software systems that are embedded, distributed likely need more systematic performance models that can leverage the quality of such systems. Towards this end many techniques came into existence. This paper throws light into software performance analysis and its present state-of-the-art. It reviews different design models and performance models that provide valuable insights to make well informed decisions

    IMPLEMENTATION OF MASSIVE MIMO IN SUB-6 GHZ AND MMWAVE TECHNOLOGY USING HYBRID PRECODING

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    The massive multiple input multiple output (MIMO) uses arrays with many antennas at the BS to provide vast signal amplification by beamforming and high spatial resolution to multiplex many simultaneous users. Although small-scale MIMO technology has been around for decades, the practical gains have been modest due to the small number of antennas which seldom give sufficient spatial resolution to support many spatially multiplexed streams. Massive MIMO has been demonstrated to achieve an order-of-magnitude higher spectral efficiency in real life, with practical acquisition of channel state information (CSI). 3GPP is steadily increasing the maximum number of antennas in long term evaluation (LTE) and since 64 antennas are supported in Release 15, Massive MIMO has become an integral component of 5G. This work implemented these differences and their implications, while dispelling common misunderstandings. Building on this foundation, we suggest appropriate signal precoding schemes and use cases to efficiently exploit Massive MIMO in both frequencies

    Research Journal of Pharmaceutical, Biological and Chemical Sciences An Analytical Method Development and Validation for Simultaneous Estimation of Atazanavir and Ritonavir in Tablet Dosage Forms by Using UPLC

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    ABSTRACT The present work was undertaken with the aim to develop and validate a rapid and consistent UPLC method in which the peaks will be appear with short period of time as per ICH guidelines. The UPLC separation was achieved on a Symmetry C 18 (2.1 x 50 mm, 1.7 m, Make: BEH) or equivalent in an isocratic mode. The mobile phase was composed of phosphate buffer (40%) [pH 2.5] and acetonitrile (60%). The flow rate was monitored at 0.25 ml per min. The wavelength selected for the detection was 249 nm. The run time was 4 min. The retention time found for Atazanavir and Ritonavir were 0.819 and 1.236 min. respectively. The % recovery was found 98.75 -101.01 % for Atazanavir and 99.05 -100.39 % for Ritonavir. The linearity was established in the range of 30 to 90 g/ml for Atazanavir and 10 to 30 g/ml for Ritonavir. The LOD found for Atazanavir and Ritonavir were 0.026 and 0.048 µg/ml respectively. The LOQ found for Atazanavir and Ritonavir were 0.096 and 0.15 µg/ml respectively. Overall the proposed method was found to be suitable, sensitive, reproducible, specific and accurate for the quantitative determination of the drug in tablet dosage form

    CSU_Cares Healthcare application

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    a. Software engineering project b. Python , PyCharm IDE , HTML,CSS,Java Script c. It has the login to the application from where they can be navigated to the insurance calculator , Doctors available , Symptoms detected which will help them to diagnose the disease

    STABILITY INDICATING RP-HPLC METHOD DEVELOPMENT & VALIDATION FOR SIMULTANEOUS DETERMINATION OF DUTASTERIDE AND TAMSULOSIN IN BULK AS WELL AS IN PHARMACEUTICAL DOSAGE FORM BY USING PDA DETECTOR

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    ABSTRACT Objective: The present work was undertaken with the aim to develop and validate a rapid and consistent stability indicating RP-HPLC in which the peaks will be appear with short period of time as per ICH Guidelines. The proposed method was simple, fast, accurate and precise method for the Quantification of drug in the dosage form, bulk drug as well as for routine analysis in Quality control. Method: Reversed-phase high-performance liquid chromatography (RP-HPLC) methods was developed and validated for simultaneous estimation of Tamsulosin hydrochloride and Dutasteride in bulk drug and in combined dosage forms. RP-HPLC separation was achieved on a Symmetry C18 (4.6 x 150mm, 5mm, Make: XTerra) under an Isocratic Mode. The mobile phase was composed of Phosphate Buffer (20%) whose pH was adjusted to 2.5 by using Orthophosporic Acid & Acetonitrile (80%) [HPLC Grade]. The flow rate was monitored at 0.8 ml per min. The wavelength was selected for the detection was 274 nm. Result: The run time was 7min. The retention time found for the drugs Dutasteride & Tamsulosin were 2.003 min. & 5.067 min. respectively. The linearity was established in the range of 25 to 125µg/ml. The proposed method was adequate sensitive, reproducible, and specific for the determination of Dutasteride and Tamsulosin hydrochloride in bulk as well as in Pharmaceutical dosage form. The validation of method was carried out utilizing ICH-guidelines. Conclusion: The described RP-HPLC method was successfully employed for the analysis of pharmaceutical formulations containing combined dosage form. The drug was exposed to Thermal, Hydrolytic and Oxidative stress conditions and the stressed samples were analyzed by the proposed method. The peak homogeneity data for the drugs Dutasteride and Tamsulosin hydrochloride were obtained by using Photodiode Array Detector in the stressed sample chromatograms which demonstrated the specificity of the method for the estimation in the presence of degradants. Overall the proposed method was found to be suitable and Accurate for the Quantitative determination and stability study of the drug in Pharmaceutical dosage form. . The method was effectively separated the drug from its degradation product and it was employed as a stability- indicating one. The method was simple, precise, accurate and sensitive and applicable for the simultaneous determination of Dutasteride and Tamsulosin hydrochloride in bulk drug and in combined dosage forms. Keywords: Tamsulosin, Dutasteride, ICH Guideline, RP-HPLC, LOD, LOQ
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