Conceptual design of a fixed-pitch wind turbine generator system rated at 400 kilowatts

The design and cost aspects of a fixed pitch, 400 kW Wind Turbine Generator (WTG) concept are presented. Improvements in reliability and cost reductions were achieved with fixed pitch operation and by incorporating recent advances in WTG technology. The specifications for this WTG concept were as follows: (1) A fixed pitch, continuous wooden rotor was to be provided by the Gougeon Bros. Co. (2) An 8 leg hyperboloid tower that showed promise as a low cost structure was to be used. (3) Only commercially available components and parts that could be easily fabricated were to be considered. (4) Design features deemed desirable based on recent NASA research efforts were to be incorporated. Detailed costs and weight estimates were prepared for the second machine and a wind farm of 12 WTG's. The calculated cost of energy for the fixed pitch, twelve unit windfarm is 11.5 cents/kW hr not including the cost of land and access roads. The study shows feasibility of fixed pitch, intermediate power WTG operation

Occurrence of a Gynandromorphic Bombus bimaculatus (Hymenoptera: Apidae) in Southeastern Ohio

Herein, we introduce the first reported case of gynandromorphy in the bumblebee Bombus bimaculatus (Cresson) (Hymenoptera: Apidae), a relatively common North American species found east of the Mississippi River. The specimen was collected in Marietta, Ohio as part of a bee diversity assessment project for Washington County. Gynanders exhibit discrete male and female characters in a single individual. We discuss the potential causes of gynandromorphy exhibited by this specimen, which has differing antennal segments (12 and 13), facial maculation, abdominal hair coloration, and the presence of a corbicula – secondary sex characters that are characteristic for the genus Bombus

Rational methods for the selection of diverse screening compounds.

Traditionally a pursuit of large pharmaceutical companies, high-throughput screening assays are becoming increasingly common within academic and government laboratories. This shift has been instrumental in enabling projects that have not been commercially viable, such as chemical probe discovery and screening against high-risk targets. Once an assay has been prepared and validated, it must be fed with screening compounds. Crafting a successful collection of small molecules for screening poses a significant challenge. An optimized collection will minimize false positives while maximizing hit rates of compounds that are amenable to lead generation and optimization. Without due consideration of the relevant protein targets and the downstream screening assays, compound filtering and selection can fail to explore the great extent of chemical diversity and eschew valuable novelty. Herein, we discuss the different factors to be considered and methods that may be employed when assembling a structurally diverse compound collection for screening. Rational methods for selecting diverse chemical libraries are essential for their effective use in high-throughput screens.We are grateful for financial support from the MRC, Wellcome Trust, CRUK, EPSRC, BBSRC and Newman Trust.This is the author accepted manuscript. The final version is available from American Chemical Society via http://dx.doi.org/10.1021/cb100420

Effect of Pelleting Temperature on the Activity of Different Enzymes

The effects of different pelleting temperatures on the activity of cellulase, bacterial amylase, fungal amylase, and pentosanase were tested. Samples of a commercial barley-wheat-soybean diet containing different enzyme preparations were pelleted at 60, 70, 80, 90, and 100 C (pellet temperature measured at the die outlet) through a die containing holes 2.5 mm in diameter. Enzymatic analyses were conducted on either soluble substrates or by measuring the ability of the tested enzymes to decrease the viscosity of the diet. Measurements made on soluble substrates suggest that cellulase, fungal amylase, and pentosanase maintained activity when being pelleted at temperatures up to 80 C and bacterial amylase maintained activity at temperatures up to 90 C. Pentosanase and amylases showed little or no effect on the viscosity of the diet. Cellulase addition decreased the viscosity at all temperature levels, even after being pelleted at 90 and 100 C (P < 0.05). No cellulolytic activity was detected on the soluble substrate after these pelleting temperatures. Measurements on a soluble substrate might therefore not always reflect the true stability of a preparation because the ability of a carbohydrase to decrease the viscosity of the digesta is important to its effect in the gastrointestinal tract. Measurements on soluble substrates suggest that cellulase, fungal amylase, and pentosanase can be pelleted at temperatures up to at least 80 C and bacterial amylase up to 90 C without a considerable loss in analyzed activit

Investigations on the slope efficiency of a pulsed 2.8-µm Er3+:LiYF4 laser

A slope efficiency of 40% from an Er3+:LiYF4 laser is demonstrated under pulsed Ti:sapphire pumping at 973 nm. With reduction of the pump-pulse duration a significant decrease of the slope efficiency and an increase of the threshold is observed in the experiment and confirmed with high accuracy in a computer simulation. This behavior is due to interionic upconversion from the lower laser level, which leads to energy recycling into the upper laser level. The upconversion rate is negative at threshold but increases strongly with rising pump pulse energy, thus enhancing the slope efficiency. The conditions are derived that are necessary for achieving the high slope efficiency of the energy-recycling regime

Quantum protocols for anonymous voting and surveying

We describe quantum protocols for voting and surveying. A key feature of our schemes is the use of entangled states to ensure that the votes are anonymous and to allow the votes to be tallied. The entanglement is distributed over separated sites; the physical inaccessibility of any one site is sufficient to guarantee the anonymity of the votes. The security of these protocols with respect to various kinds of attack is discussed. We also discuss classical schemes and show that our quantum voting protocol represents a N-fold reduction in computational complexity, where N is the number of voters.Comment: 8 pages. V2 includes the modifications made for the published versio

Skylab S-193 Radscat microwave measurements of sea surface winds

The S-193 Radscat made extensive measurements of many sea conditions. Measurements were taken in a tropical hurricane (Ava), a tropical storm (Christine), and in portions of extratropical cyclones. Approximately 200 scans of ocean data at 105 kilometer spacings were taken during the first two Skylab missions and another 200 during the final mission when the characteristics of the measurements changed due to damage of the antenna. Backscatter with four transmit/receive polarization combinations and emissions with horizontal and vertical receive polarizations were measured. Other surface parameters investigated for correlation with the measurements included sea temperature, air/sea temperature difference, and gravity-wave spectrum. Methods were developed to correct the microwave measurements for atmospheric effects. The radiometric data were corrected accurately for clear sky and light cloud conditions only. The radiometer measurements were used to recover the surface scattering characteristics for all atmospheric conditions excluding rain. The radiometer measurements also detected the presence of rain which signaled when the scattering measurement should not be used for surface wind estimation. Regression analysis was used to determine empirically the relation between surface parameters and the microwave measurements, after correction for atmospheric effects. Results indicate a relationship approaching square-law at 50 deg between differential scattering coefficient and wind speed with horizontally polarized scattering data showing slightly more sensitivity to wind speed than vertically polarized data

Importance of relative humidity in the oxidative ageing of organic aerosols: case study of the ozonolysis of maleic acid aerosol

Many important atmospheric aerosol processes depend on the chemical composition of the aerosol, e.g. water uptake and particle cloud interactions. Atmospheric ageing processes, such as oxidation reactions, significantly and continuously change the chemical composition of aerosol particles throughout their lifetime. These ageing processes are often poorly understood. In this study we utilize an aerosol flow tube set up and an ultra-high resolution mass spectrometer to explore the effect of relative humidity (RH) in the range of &lt;5–90% on the ozonolysis of maleic acid aerosol which is employed as model organic aerosol system. Due to the slow reaction kinetics relatively high ozone concentrations of 160–200 ppm were used to achieve an appreciable degree of oxidation of maleic acid. The effect of oxidative ageing on the hygroscopicity of maleic acid particles is also investigated using an electrodynamic balance and thermodynamic modelling. RH has a profound effect on the oxidation of maleic acid particles. Very little oxidation is observed at RH &lt; 50% and the only observed reaction products are glyoxylic acid and formic acid. In comparison, when RH &gt; 50% there are about 15 oxidation products identified. This increased oxidation was observed even when the particles were exposed to high humidities long after a low RH ozonolysis reaction. This result might have negative implications for the use of water as an extraction solvent for the analysis of oxidized organic aerosols. These humidity-dependent differences in the composition of the ozonolyzed aerosol demonstrate that water is both a key reactant in the oxidation scheme and a determinant of particle phase and hence diffusivity. The measured chemical composition of the processed aerosol is used to model the hygroscopic growth, which compares favourably with water uptake results from the electrodynamic balance measurements. A reaction mechanism is presented which takes into account the RH dependent observations. This study emphasises the importance of studying the combined effects of several atmospheric parameters such as oxidants and RH to accurately describe the complex oxidation scheme of organic aerosols

Evaluating the outcomes of a podiatry-led assessment service in a public hospital orthopaedic unit

BACKGROUND: In Australia, the demand for foot and ankle orthopaedic services in public health settings currently outweighs capacity. Introducing experienced allied health professionals into orthopaedic units to initiate the triage, assessment and management of patients has been proposed to help meet demand. The aim of this study was to evaluate the effect of introducing a podiatry-led assessment service in a public hospital orthopaedic unit. The outcomes of interest were determining: the proportion of patients discharged without requiring an orthopaedic appointment, agreement in diagnosis between the patient referral and the assessing podiatrist, the proportion of foot and ankle conditions presenting to the service, and the proportion of each condition to require an orthopaedic appointment. METHODS: This study audited the first 100 patients to receive an appointment at a new podiatry-led assessment service. The podiatrist triaged ‘Category 3’ referrals consisting of musculoskeletal foot and ankle conditions and appointments were provided for those considered likely to benefit from non-surgical management. Following assessment, patients were referred to an appropriate healthcare professional or were discharged. At the initial appointment or following a period of care, patients were discharged if non-surgical management was successful, surgery was not indicated, patients did not want surgery, and if patient’s failed to attend their appointments. All other patients were referred for an orthopaedic consultation as indicated. RESULTS: Ninety-five of the 100 patients (69 females and 31 males; mean age 51.9, SD 16.4 years) attended their appointment at the podiatry-led assessment service. The 95 referrals contained a total of 107 diagnoses, of which the podiatrist agreed with the diagnosis stated on the referral in 56 cases (Kappa =0.49, SE = 0.05). Overall, 34 of the 100 patients were referred to an orthopaedic surgeon and the remaining 66 patients were discharged from the orthopaedic waiting list without requiring an orthopaedic consultation. CONCLUSIONS: Two-thirds of patients who had an appointment at the podiatry-led assessment service were discharged without requiring a surgical consultation. The introduction of a podiatry-led service assists with timely provision of patient care and ensures those with the greatest need for orthopaedic surgery have improved access to specialist care