Pro’s and Con’s of a reverse-auction to evaluate conservation easements

Resource /Energy Economics and Policy,

Impact of price differentials and limited storage on soybean flows in West Tennessee, 1977

The purpose of this study was to determine to what extent farm and country elevator storage affects present observed soybean flows in West Tennessee and to estimate the consequences brought about by certain soybean price increases at Memphis with respect to the attraction of West Tennessee grown soybeans into Memphis for processing. The method employed in the study was the use of a linear programming format, containing four quarters and five subregions. The multi-time dimension was necessary in order to capture the storage aspect in a commodity such as soybeans. The five subregions were used in order to depict the major marketing options and restrictions particular to each subregion. The model was constructed by using secondary data for transportation, storage, and production estimates and primary data obtained from a recent grain handling survey for estimating the 1977 grain flows in the study area. The major conclusions of the study were: 1) farm and country elevator storage in West Tennessee does not seem to be a problem hindering increased soybean flows from West Tennessee into Memphis and 2) soybean prices at Memphis do not seem high enough at the present time to justify the additional transportation charges that would be incurred with additional soybean shipments from West Tennessee. This implies that certain price increases could be initiated by the Memphis processors to encourage additional soybean shipments from West Tennessee

A Producer's Propensity to Conserve Framework: Application to a US and Australian Conservation Program

Increasing recognition of the environmental impact of agriculture has led to increasing public activity around the world encouraging public conservation programs. Different countries have taken different program approaches to accomplish this. The comparison and contrast here is between Australia and the United States, examining the CREP program in the U.S. and the Eco Tender program in Australia. A different historical experience in the U.S. sets certain parameters that are expected in their conservation programs. To some extent, the Australian program could take more of a clean slate approach. The Australian program is able to take a broader landscape approach, specifically considering multiple benefits with knowledge about off-site benefits as well. This is tied into a structured auction process that does not allow gaming of the auction process. While the U.S. approach does include a bidding process, its structure is such that it has characteristics of an incentive program. The U.S. approach also gives less incentive to farmers to provide environmental amenities at the lowest possible cost. Taking off-site impacts into consideration and finding ways to induce competition among farmers to provide amenities at the lowest cost to the public are seen as important characteristics of cost effective conservation programs.Resource /Energy Economics and Policy,

A Hierarchical Architecture for the Coordination of an Ensemble of Steam Generators

This work presents a hierarchical architecture for the optimal management of an ensemble of steam generators, which needs to jointly sustain a common load. The coordination of independent subsystems is provided by a multi-layer control scheme. A high-level optimizer computes the optimal shares of production to be allocated to single generators. At medium level, a robust tube-based model predictive control (MPC) is proposed to track the time-varying demand of the ensemble using a centralized, but aggregated model, whose order does not scale with the number of subsystems. At low level, decentralized controllers are in place to stabilize the internal boiler pressure. The control architecture enables the dynamic modification of the ensemble configuration and plug and play operations. Simulation results are reported to demonstrate the potentialities of the proposed approach

Quantum Cryptography

Quantum cryptography could well be the first application of quantum mechanics at the individual quanta level. The very fast progress in both theory and experiments over the recent years are reviewed, with emphasis on open questions and technological issues.Comment: 55 pages, 32 figures; to appear in Reviews of Modern Physic

Optimal management of asymptomatic carotid stenosis in 2021: the jury is still out. An International, multispecialty, expert review and position statement

Objectives: The recommendations of international guidelines for the management of asymptomatic carotid stenosis (ACS) often vary considerably and extend from a conservative approach with risk factor modification and best medical treatment (BMT) alone, to a more aggressive approach with a carotid intervention plus BMT. The aim of the current multispecialty position statement is to reconcile the conflicting views on the topic. Materials and methods: A literature review was performed with a focus on data from recent studies. Results: Several clinical and imaging high-risk features have been identified that are associated with an increased long-term ipsilateral ischemic stroke risk in patients with ACS. Such high-risk clinical/imaging features include intraplaque hemorrhage, impaired cerebrovascular reserve, carotid plaque echolucency/ulceration/ neovascularization, a lipid-rich necrotic core, a thin or ruptured fibrous cap, silent brain infarction, a contralateral transient ischemic attack/stroke episode, male patients <75 years and microembolic signals on transcranial Doppler. There is growing evidence that 80-99% ACS indicate a higher stroke risk than 50-79% stenoses. Conclusions: Although aggressive risk factor control and BMT should be implemented in all ACS patients, several high-risk features that may increase the risk of a future cerebrovascular event are now documented. Consequently, some guidelines recommend a prophylactic carotid intervention in high-risk patients to prevent future cerebrovascular events. Until the results of the much-anticipated randomized controlled trials emerge, the jury is still out regarding the optimal management of ACS patients

Optimal Management of Asymptomatic Carotid Stenosis in 2021:The Jury is Still Out. An International, Multispecialty, Expert Review and Position Statement

Objectives: The recommendations of international guidelines for the management of asymptomatic carotid stenosis (ACS) often vary considerably and extend from a conservative approach with risk factor modification and best medical treatment (BMT) alone, to a more aggressive approach with a carotid intervention plus BMT. The aim of the current multispecialty position statement is to reconcile the conflicting views on the topic. Materials and methods: A literature review was performed with a focus on data from recent studies. Results: Several clinical and imaging high-risk features have been identified that are associated with an increased long-term ipsilateral ischemic stroke risk in patients with ACS. Such high-risk clinical/imaging features include intraplaque hemorrhage, impaired cerebrovascular reserve, carotid plaque echolucency/ulceration/ neovascularization, a lipid-rich necrotic core, a thin or ruptured fibrous cap, silent brain infarction, a contralateral transient ischemic attack/stroke episode, male patients < 75 years and microembolic signals on transcranial Doppler. There is growing evidence that 80–99% ACS indicate a higher stroke risk than 50–79% stenoses. Conclusions: Although aggressive risk factor control and BMT should be implemented in all ACS patients, several high-risk features that may increase the risk of a future cerebrovascular event are now documented. Consequently, some guidelines recommend a prophylactic carotid intervention in high-risk patients to prevent future cerebrovascular events. Until the results of the much-anticipated randomized controlled trials emerge, the jury is still out regarding the optimal management of ACS patients

Optical imaging and spectroscopy for the study of the human brain: status report.

This report is the second part of a comprehensive two-part series aimed at reviewing an extensive and diverse toolkit of novel methods to explore brain health and function. While the first report focused on neurophotonic tools mostly applicable to animal studies, here, we highlight optical spectroscopy and imaging methods relevant to noninvasive human brain studies. We outline current state-of-the-art technologies and software advances, explore the most recent impact of these technologies on neuroscience and clinical applications, identify the areas where innovation is needed, and provide an outlook for the future directions

New approaches to the study of human brain networks underlying spatial attention and related processes

Cognitive processes, such as spatial attention, are thought to rely on extended networks in the human brain. Both clinical data from lesioned patients and fMRI data acquired when healthy subjects perform particular cognitive tasks typically implicate a wide expanse of potentially contributing areas, rather than just a single brain area. Conversely, evidence from more targeted interventions, such as transcranial magnetic stimulation (TMS) or invasive microstimulation of the brain, or selective study of patients with highly focal brain damage, can sometimes indicate that a single brain area may make a key contribution to a particular cognitive process. But this in turn raises questions about how such a brain area may interface with other interconnected areas within a more extended network to support cognitive processes. Here, we provide a brief overview of new approaches that seek to characterise the causal role of particular brain areas within networks of several interacting areas, by measuring the effects of manipulations for a targeted area on function in remote interconnected areas. In human participants, these approaches include concurrent TMS-fMRI and TMS-EEG, as well as combination of the focal lesion method in selected patients with fMRI and/or EEG measures of the functional impact from the lesion on interconnected intact brain areas. Such approaches shed new light on how frontal cortex and parietal cortex modulate sensory areas in the service of attention and cognition, for the normal and damaged human brain

Single domain antibodies: promising experimental and therapeutic tools in infection and immunity

Antibodies are important tools for experimental research and medical applications. Most antibodies are composed of two heavy and two light chains. Both chains contribute to the antigen-binding site which is usually flat or concave. In addition to these conventional antibodies, llamas, other camelids, and sharks also produce antibodies composed only of heavy chains. The antigen-binding site of these unusual heavy chain antibodies (hcAbs) is formed only by a single domain, designated VHH in camelid hcAbs and VNAR in shark hcAbs. VHH and VNAR are easily produced as recombinant proteins, designated single domain antibodies (sdAbs) or nanobodies. The CDR3 region of these sdAbs possesses the extraordinary capacity to form long fingerlike extensions that can extend into cavities on antigens, e.g., the active site crevice of enzymes. Other advantageous features of nanobodies include their small size, high solubility, thermal stability, refolding capacity, and good tissue penetration in vivo. Here we review the results of several recent proof-of-principle studies that open the exciting perspective of using sdAbs for modulating immune functions and for targeting toxins and microbes