Tutorial The Fresnel

volume and transmitted wave

The formation of caustics in two- and three-dimensional media. Geophys

In terms of ray theory, the concept of caustics is understood as the focus point in space through which rays go. The consequence of the generation of caustics in a wave®eld is, in the ray geometrical limit, that the amplitude in the wave®el

Development of seismicity and probabilistic hazard assessment for the Groningen gas field

The increase in number and strength of shallow induced seismicity connected to the Groningen gas field since 2003 and the occurrence of a M L 3.6 event in 2012 started the development of a full probabilistic seismic hazard assessment (PSHA) for Groningen, required by the regulator. Densification of the monitoring network resulted in a decrease of the location threshold and magnitude of completeness down to ∼ M L = 0.5. Combined with a detailed local velocity model, epicentre accuracy could be reduced from 0.5–1 km to 0.1–0.3 km and a vertical resolution ∼0.3 km. Time-dependent seismic activity is observed and taken into account into PSHA calculations. Development of the Ground Motion Model for Groningen resulted in a significant reduction of the hazard. Comparison of different implementations of the PSHA, using different source models, based on either a compaction model and production scenarios or on extrapolation of past seismicity, and methods of calculation, shows similar result

Validation of first-order diffraction theory for the traveltimes and amplitudes of propagating waves

Ultrasonic measurements of acoustic wavefields scattered by single spheres placed in a homogenous background medium (water) are presented. The dimensions of the spheres are comparable to the wavelength and the wavelength and represent both positive (rubber) and negative (teflon) velocity anomalies with respect to the background medium. The sensitivity of the recorded wavefield to scattering in terms of traveltime delay and amplitude variation is investigated. The results validate a linear (first-order) diffraction theory for wavefields propagating in heterogeneous media with anomaly contrasts on the order of ±15%. The diffraction theory is compared further with the exact results known from literature for scattering from an elastic sphere, formulated in terms of Legendre polynomials. To investigate the 2D case, the first-order scattering theory is tested against 2D elastic finite-difference calculations. As the presented theory involves a volume integral, it is applicable to any geometric shape, and the scattering object does not need to be spherical or any other specific symmetrical shape. Furthermore, it can be implemented easily in seismic data inversion schemes, which is illustrated with examples from seismic crosswell tomography and a reflection experiment.GeotechnologyCivil Engineering and Geoscience

A database of ground motion recordings, site profiles, and amplification factors from the Groningen gas field in the Netherlands

A comprehensive database that has been used to develop ground motion models for induced earthquakes in the Groningen gas field is provided in a freely accessible online repository. The database includes more than 8500 processed ground motion recordings from 87 earthquakes of local magnitude ML between 1.8 and 3.6, obtained from a large network of surface accelerographs and borehole geophones placed at 50 m depth intervals to a depth of 200 m. The 5%-damped pseudo-acceleration spectra and Fourier amplitude spectra of the records are also provided. Measured shear-wave velocity (VS) profiles, obtained primarily from seismic Cone Penetration Tests (CPTs), are provided for 80 of the ∼100 recording stations. A model representing the regional dynamic soil properties is presented for the entire gas field plus a 5 km onshore buffer zone, specifying lithology, VS, and damping for all layers above the reference baserock horizon located at about 800 m depth. Transfer functions and frequency-dependent amplification factors from the reference rock horizon to the surface for the locations of the recording stations are also included. The database provides a valuable resource for further refinement of induced seismic hazard and risk modeling in Groningen as well as for generic research in site response of thick, soft soil deposits and the characteristics of ground motions from small-magnitude, shallow-focus induced earthquakes. </jats:p

Ground-motion records, site profiles and amplification factors from the Groningen field, the Netherlands

A comprehensive database that has been used to develop ground-motion models for induced earthquakes in the Groningen gas field is provided. The database includes more than 8,500 processed ground-motion recordings from 87 earthquakes of local magnitude ML between 1.8 and 3.6, obtained from a large network of surface accelerographs and borehole geophones at 50 m intervals to a depth of 200 m. The 5%-damped pseudo acceleration spectra and Fourier amplitude spectra of the records are also provided. Measured shear-wave velocity (VS) profiles, obtained primarily from seismic CPTs, are provided for 80 of the ~100 recording stations. A geological model for the entire gas field plus a 5 km onshore buffer zone, specifying lithology, VS and damping for all layers above the reference baserock horizon located at about 800 m depth is also provided. For the locations of the recording station, the database includes transfer functions and non-linear frequency-dependent amplification factors from the reference rock horizon to the surface. The database provides a valuable resource for further refinement of induced seismic hazard and risk modeling in Groningen as well as for generic research in site response of thick, soft soil deposits and the characteristics of ground motions from small-magnitude, shallow-focus induced earthquakes. The data herein are presented and discussed in the paper of Ntinalexis et al. (2023), available at https://doi.org/10.1177/87552930221140926

Identification and in Vivo and in Vitro Characterization of Long Acting and Melanocortin 4 Receptor (MC4-R) Selective α-Melanocyte-Stimulating Hormone (α-MSH) Analogues

We report in vitro and in vivo data of new α-melanocyte-stimulating hormone (α-MSH) analogues which are N-terminal modified with a long chain fatty acid derivative. While keeping the pharmacophoric motif (d-Phe-Arg-Trp) fixed, we tried to improve selectivity and physicochemical parameters like solubility and stability of these analogues by replacing amino acids further away from the motif. Receptor specific changes in binding affinity to the melanocortin receptors were observed between the acetyl derivatives and the fatty acid analogues. Furthermore, amino acids at the N-terminal of α-MSH (Ser-Tyr-Ser) not considered to be part of the pharmacophore were found to have an influence on the MC4/MC1 receptor selectivity. While the acetyl analogues have an in vivo effect for around 7 h, the long chain fatty acid analogues have an effect up to 48 h in an acute feeding study in male Sprague–Dawley rats after a single subcutaneous administration