31 research outputs found
Room temperature coexistence of large electric polarization and magnetic order in BiFeO3 single crystals
From an experimental point of view, room temperature ferroelectricity in
BiFeO3 is raising many questions. Electric measurements made a long time ago on
solid-solutions of BiFeO3 with Pb(Ti,Zr)O3 indicate that a spontaneous electric
polarization exists in BiFeO3 below the Curie temperature TC=1143K. Yet in most
reported works, the synthesised samples are too conductive at room temperature
to get a clear polarization loop in the bulk without any effects of extrinsic
physical or chemical parameters. Surprisingly, up to now there has been no
report of a P(E) (polarization versus electric field) loop at room temperature
on single crystals of BiFeO3. We describe here our procedure to synthesize
ceramics and to grow good quality sizeable single crystals by a flux method. We
demonstrate that BiFeO3 is indeed ferroelectric at room-temperature through
evidence by Piezoresponse Force Microscopy and P(E) loops. The polarization is
found to be large, around 60 microC/cm2, a value that has only been reached in
thin films. Magnetic measurements using a SQUID magnetometer and Mossbauer
spectroscopy are also presented. The latter confirms the results of NMR
measurements concerning the anisotropy of the hyperfine field attributed to the
magnetic cycloidal structure.Comment: 27 pages, 12 figure
ΠΠ°ΡΠ΅ΠΌΠ°ΡΠΈΠΊΠΎ-ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠ°Ρ ΠΎΡΠ΅Π½ΠΊΠ° ΠΏΠ΅ΡΡΠΈΡΡΠΈΡΡΡΡΠΈΡ Π²ΠΎΠ·Π±ΡΠ΄ΠΈΡΠ΅Π»Π΅ΠΉ ΠΊΠ°ΠΊ ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΡΠΈΡΠΊΠ° Π²Π½Π΅Π±ΠΎΠ»ΡΠ½ΠΈΡΠ½ΠΎΠΉ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠΈ ΠΈ ΠΎΡΡΡΠΎΠ³ΠΎ Π±ΡΠΎΠ½Ρ ΠΈΡΠ° Ρ Π΄Π΅ΡΠ΅ΠΉ
The aim of this study was to determine the relationship between infection with βpersistentβ agents of children and the possibility of the development of inflammatory diseases of the respiratory tract such as community-acquired pneumonia and acute bronchitis on the basis of risk management concepts.Materials and methods. 701 children in age from 15 days to 16 years were examined in Nizhny Novgorod and the Nizhny Novgorod region with clinically and radiologically confirmed diagnosis: community-acquired pneumonia, acute bronchitis. This study was performed in the period from 2005 to 2014. The control group consisted of 127 healthy children of different ages. The detection of M. pneumoniae, Π‘ytomegalovirus, Herpes simplex I/II C. pneumoniae was performed by PCR. The concept of risk determination was based on the determination of the absolute risk in the exposed and the no exposed groups, attributable risk, relative risk, the population attributable risk, as well as determining the standard errors for each type of risk and confidence interval.Results. Attributable risk, relative risk, population-attributable risk are statistically significant figures. Attributable risk of development of community-acquired pneumonia was 29,26%; 27,37%; 25,70%; 20,21% for the M. pneumoniae, C. pneumoniae, CMV, HSV I / II respectively. The relative risk was 1,43 for the M. pneumoniae; 1,38 β for C. pneumoniae and CMV; 1,28- for HSV I / II. The presence of persistent pathogens is resulting in increased incidence of communityacquired pneumonia throughout the population (population attributable risk): 4,75% for M. pneumoniae, 0,23% for C. pneumoniae, 5,59% for the CMV and 1,08% for the HSV I/II. Similar calculations were performed for patients with acute bronchitis. The statistical analysis allowed to exclude C. pneumoniae and HSV I / II of the risk factors for communityacquired pneumonia and acute bronchitis.Conclusion. The findings suggest the influence of M. pneumoniae and CMV in the development of communityacquired pneumonia and acute bronchitis in children. C. pneumoniae, and HSV I / II do not play a statistically significant role in the overall landscape of etiologic agents of community-acquired pneumonia and acute bronchitis.Π¦Π΅Π»ΡΡ Π΄Π°Π½Π½ΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠ²ΠΈΠ»ΠΎΡΡ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ ΡΠ²ΡΠ·ΠΈ ΠΌΠ΅ΠΆΠ΄Ρ ΠΈΠ½ΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΡΡΡΡ Β«ΠΏΠ΅ΡΡΠΈΡΡΠΈΡΡΡΡΠΈΠΌΠΈΒ» Π²ΠΎΠ·Π±ΡΠ΄ΠΈΡΠ΅Π»ΡΠΌΠΈ Π΄Π΅ΡΠ΅ΠΉ ΠΈ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡΡ ΡΠ°Π·Π²ΠΈΡΠΈΡ Π²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΡΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΡΠ΅ΡΠΏΠΈΡΠ°ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°ΠΊΡΠ°, ΡΠ°ΠΊΠΈΡ
ΠΊΠ°ΠΊ Π²Π½Π΅Π±ΠΎΠ»ΡΠ½ΠΈΡΠ½Π°Ρ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΡ ΠΈ ΠΎΡΡΡΡΠΉ Π±ΡΠΎΠ½Ρ
ΠΈΡ Π½Π° ΠΎΡΠ½ΠΎΠ²Π°Π½ΠΈΠΈ ΠΊΠΎΠ½ΡΠ΅ΠΏΡΠΈΠΈ ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΡΠΈΡΠΊΠΎΠ².ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. Π ΠΏΠ΅ΡΠΈΠΎΠ΄ Ρ 2005 ΠΏΠΎ 2014 Π³. ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ 701 ΡΠ΅Π±Π΅Π½ΠΎΠΊ ΠΈΠ· Π³. ΠΠΈΠΆΠ½Π΅Π³ΠΎ ΠΠΎΠ²Π³ΠΎΡΠΎΠ΄Π° ΠΈ ΠΠΈΠΆΠ΅Π³ΠΎΡΠΎΠ΄ΡΠΊΠΎΠΉ ΠΎΠ±Π»Π°ΡΡΠΈ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ ΠΎΡ 15 Π΄Π½Π΅ΠΉ Π΄ΠΎ 16 Π»Π΅Ρ Ρ ΡΠ΅Π½ΡΠ³Π΅Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈ ΠΈ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈ ΠΏΠΎΠ΄ΡΠ²Π΅ΡΠΆΠ΄Π΅Π½Π½ΡΠΌΠΈ Π΄ΠΈΠ°Π³Π½ΠΎΠ·Π°ΠΌΠΈ: Π²Π½Π΅Π±ΠΎΠ»ΡΠ½ΠΈΡΠ½Π°Ρ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΡ, ΠΎΡΡΡΡΠΉ Π±ΡΠΎΠ½Ρ
ΠΈΡ. ΠΠΎΠ½ΡΡΠΎΠ»ΡΠ½ΡΡ Π³ΡΡΠΏΠΏΡ ΡΠΎΡΡΠ°Π²ΠΈΠ»ΠΈ 127 ΠΏΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠΈ Π·Π΄ΠΎΡΠΎΠ²ΡΡ
Π΄Π΅ΡΠ΅ΠΉ ΡΠ°Π·Π½ΡΡ
Π²ΠΎΠ·ΡΠ°ΡΡΠΎΠ². ΠΠ΅ΡΠ΅ΠΊΡΠΈΡ M. pneumoniae, Π‘ytomegalovirus, Herpes simplex I/II C. pneumoniae ΠΎΡΡΡΠ΅ΡΡΠ²Π»ΡΠ»ΠΈ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ ΠΠ¦Π . ΠΠΎΠ½ΡΠ΅ΠΏΡΠΈΡ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΡΠΈΡΠΊΠΎΠ² ΡΡΡΠΎΠΈΠ»Π°ΡΡ Π½Π° ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠΈ Π°Π±ΡΠΎΠ»ΡΡΠ½ΠΎΠ³ΠΎ ΡΠΈΡΠΊΠ° Π² ΡΠΊΡΠΏΠΎΠ½ΠΈΡΡΠ΅ΠΌΠΎΠΉ ΠΈ Π½Π΅ ΡΠΊΡΠΏΠΎΠ½ΠΈΡΡΠ΅ΠΌΠΎΠΉ Π³ΡΡΠΏΠΏΠ°Ρ
, Π°ΡΡΠΈΠ±ΡΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΡΠΈΡΠΊΠ°, ΠΎΡΠ½ΠΎΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠΈΡΠΊΠ°, ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ Π°ΡΡΠΈΠ±ΡΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΡΠΈΡΠΊΠ°, Π° ΡΠ°ΠΊΠΆΠ΅ Π½Π° ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠΈ ΡΡΠ°Π½Π΄Π°ΡΡΠ½ΡΡ
ΠΎΡΠΈΠ±ΠΎΠΊ Π΄Π»Ρ ΠΊΠ°ΠΆΠ΄ΠΎΠ³ΠΎ Π²ΠΈΠ΄Π° ΡΠΈΡΠΊΠ° ΠΈ Π΄ΠΎΠ²Π΅ΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΈΠ½ΡΠ΅ΡΠ²Π°Π»Π°.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π‘ΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈ Π·Π½Π°ΡΠΈΠΌΡΠΌΠΈ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΡΠΌΠΈ ΡΠ²Π»ΡΡΡΡΡ Π°ΡΡΠΈΠ±ΡΡΠΈΠ²Π½ΡΠΉ ΡΠΈΡΠΊ, ΠΎΡΠ½ΠΎΡΠΈΡΠ΅Π»ΡΠ½ΡΠΉ ΡΠΈΡΠΊ, ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΎΠ½Π½ΡΠΉ Π°ΡΡΠΈΠ±ΡΡΠΈΠ²Π½ΡΠΉ ΡΠΈΡΠΊ. ΠΡΡΠΈΠ±ΡΡΠΈΠ²Π½ΡΠΉ ΡΠΈΡΠΊ ΡΠ°Π·Π²ΠΈΡΠΈΡ Π²Π½Π΅Π±ΠΎΠ»ΡΠ½ΠΈΡΠ½ΠΎΠΉ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠΈ ΡΠΎΡΡΠ°Π²ΠΈΠ» 29,26%; 27,37%; 25,70%; 20,21% Π΄Π»Ρ M. pneumoniae, Π‘. pneumoniae, CMV, HSV I/II ΡΠΎΠΎΡ- Π²Π΅ΡΡΡΠ²Π΅Π½Π½ΠΎ. ΠΡΠ½ΠΎΡΠΈΡΠ΅Π»ΡΠ½ΡΠΉ ΡΠΈΡΠΊ ΡΠΎΡΡΠ°Π²ΠΈΠ» 1,43 Π΄Π»Ρ M. pneumoniae; 1,38 β Π΄Π»Ρ Π‘. pneumoniae ΠΈ Π΄Π»Ρ CMV; 1,28 β Π΄Π»Ρ HSV I/II. ΠΠ°Π»ΠΈΡΠΈΠ΅ ΠΏΠ΅ΡΡΠΈΡΡΠΈΡΡΡΡΠΈΡ
Π²ΠΎΠ·Π±ΡΠ΄ΠΈΡΠ΅Π»Π΅ΠΉ ΠΏΡΠΈΠ²ΠΎΠ΄ΠΈΡ ΠΊ ΡΠ²Π΅Π»ΠΈΡΠ΅Π½ΠΈΡ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π΅ΠΌΠΎΡΡΠΈ Π²Π½Π΅Π±ΠΎΠ»ΡΠ½ΠΈΡΠ½ΠΎΠΉ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠ΅ΠΉ ΠΏΠΎ Π²ΡΠ΅ΠΉ ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΈ (ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΎΠ½Π½ΡΠΉ Π°ΡΡΠΈΠ±ΡΡΠΈΠ²Π½ΡΠΉ ΡΠΈΡΠΊ): Π½Π° 4,75% Π΄Π»Ρ M. pneumoniae, 0,23% Π΄Π»Ρ Π‘. pneumoniae, 5,59% Π΄Π»Ρ CMV ΠΈ 1,08% Π΄Π»Ρ HSV I/II. ΠΠ½Π°Π»ΠΎΠ³ΠΈΡΠ½ΡΠ΅ ΡΠ°ΡΡΠ΅ΡΡ Π±ΡΠ»ΠΈ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½Ρ Π΄Π»Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ ΠΎΡΡΡΡΠΌ Π±ΡΠΎΠ½Ρ
ΠΈΡΠΎΠΌ. ΠΡΠΎΠ²Π΅Π΄Π΅Π½Π½ΡΠΉ ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΠΉ Π°Π½Π°Π»ΠΈΠ· ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΠ» ΠΈΡΠΊΠ»ΡΡΠΈΡΡ Π‘. pneumoniae ΠΈ HSV I/II ΠΈΠ· ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΡΠΈΡΠΊΠ° ΡΠ°Π·Π²ΠΈΡΠΈΡ Π²Π½Π΅Π±ΠΎΠ»ΡΠ½ΠΈΡΠ½ΠΎΠΉ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠΈ ΠΈ ΠΎΡΡΡΠΎΠ³ΠΎ Π±ΡΠΎΠ½Ρ
ΠΈΡΠ°.ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠΎΠ»ΡΡΠ΅Π½Π½ΡΠ΅ Π΄Π°Π½Π½ΡΠ΅ ΠΏΠΎΠ·Π²ΠΎΠ»ΡΡΡ Π³ΠΎΠ²ΠΎΡΠΈΡΡ ΠΎ Π²Π»ΠΈΡΠ½ΠΈΠΈ M. pneumoniae ΠΈ CMV Π½Π° ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ Π²Π½Π΅Π±ΠΎΠ»ΡΠ½ΠΈΡΠ½ΠΎΠΉ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠΈ ΠΈ ΠΎΡΡΡΠΎΠ³ΠΎ Π±ΡΠΎΠ½Ρ
ΠΈΡΠ° Ρ Π΄Π΅ΡΠ΅ΠΉ. Π‘. pneumoniae ΠΈ HSV I/II Π½Π΅ ΠΈΠ³ΡΠ°ΡΡ ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈ Π²Π°ΠΆΠ½ΠΎΠΉ ΡΠΎΠ»ΠΈ Π² ΠΎΠ±ΡΠ΅ΠΌ ΠΏΠ΅ΠΉΠ·Π°ΠΆΠ΅ ΡΡΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
Π°Π³Π΅Π½ΡΠΎΠ² Π²Π½Π΅Π±ΠΎΠ»ΡΠ½ΠΈΡΠ½ΠΎΠΉ ΠΏΠ½Π΅Π²ΠΌΠΎΠ½ΠΈΠΈ ΠΈ ΠΎΡΡΡΠΎΠ³ΠΎ Π±ΡΠΎΠ½Ρ
ΠΈΡΠ°
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Persistent pathogens as risk factors of community-acquired pneumonia and acute bronchitis in children
The aim of this study was to determine the relationship between infection with βpersistentβ agents of children and the possibility of the development of inflammatory diseases of the respiratory tract such as community-acquired pneumonia and acute bronchitis on the basis of risk management concepts.Materials and methods. 701 children in age from 15 days to 16 years were examined in Nizhny Novgorod and the Nizhny Novgorod region with clinically and radiologically confirmed diagnosis: community-acquired pneumonia, acute bronchitis. This study was performed in the period from 2005 to 2014. The control group consisted of 127 healthy children of different ages. The detection of M. pneumoniae, Π‘ytomegalovirus, Herpes simplex I/II C. pneumoniae was performed by PCR. The concept of risk determination was based on the determination of the absolute risk in the exposed and the no exposed groups, attributable risk, relative risk, the population attributable risk, as well as determining the standard errors for each type of risk and confidence interval.Results. Attributable risk, relative risk, population-attributable risk are statistically significant figures. Attributable risk of development of community-acquired pneumonia was 29,26%; 27,37%; 25,70%; 20,21% for the M. pneumoniae, C. pneumoniae, CMV, HSV I / II respectively. The relative risk was 1,43 for the M. pneumoniae; 1,38 β for C. pneumoniae and CMV; 1,28- for HSV I / II. The presence of persistent pathogens is resulting in increased incidence of communityacquired pneumonia throughout the population (population attributable risk): 4,75% for M. pneumoniae, 0,23% for C. pneumoniae, 5,59% for the CMV and 1,08% for the HSV I/II. Similar calculations were performed for patients with acute bronchitis. The statistical analysis allowed to exclude C. pneumoniae and HSV I / II of the risk factors for communityacquired pneumonia and acute bronchitis.Conclusion. The findings suggest the influence of M. pneumoniae and CMV in the development of communityacquired pneumonia and acute bronchitis in children. C. pneumoniae, and HSV I / II do not play a statistically significant role in the overall landscape of etiologic agents of community-acquired pneumonia and acute bronchitis