7,433 research outputs found

    Radiobiological studies of plants orbited in biosatellite 2

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    Radiation induced mutation rates and cyotlogical changes in plants orbited on Biosatellite

    No-till Forage Establishment in Alaska

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    We assessed the effectiveness of no-till forage establishment at six Alaska locations: Anchor Point, Sterling, Point MacKenzie, Palmer, Delta Junction, and Fairbanks. Directly seeding grass into established grass stands generally did not improve forage yields or quality. Seeding rate had little effect on establishment of newly seeded forages in no-till. Grass yields were depressed when companion crop yields were high, and they typically did not recover in subsequent years. Red clover established well, producing high yields of good quality forage under no-till at Point MacKenzie, but established poorly at Anchor Point and Delta Junction. These results indicated that no-till seeding of most forage crops into declining grass stands is not likely to be successful in Alaska with current available technology

    Highly challenging balance program reduces fall rate in Parkinson disease

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    Published in final edited form as: J Neurol Phys Ther. 2016 January ; 40(1): 24–30. doi:10.1097/NPT.0000000000000111BACKGROUND AND PURPOSE: There is a paucity of effective treatment options to reduce falls in Parkinson disease (PD). Although a variety of rehabilitative approaches have been shown to improve balance, evidence of a reduction in falls has been mixed. Prior balance trials suggest that programs with highly challenging exercises had superior outcomes. We investigated the effects of a theory-driven, progressive, highly challenging group exercise program on fall rate, balance, and fear of falling. METHODS: Twenty-three subjects with PD participated in this randomized cross-over trial. Subjects were randomly allocated to 3 months of active balance exercises or usual care followed by the reverse. During the active condition, subjects participated in a progressive, highly challenging group exercise program twice weekly for 90 minutes. Outcomes included a change in fall rate over the 3-month active period and differences in balance (Mini-Balance Evaluation Systems Test [Mini-BESTest]), and fear of falling (Falls Efficacy Scale-International [FES-I]) between active and usual care conditions. RESULTS: The effect of time on falls was significant (regression coefficient = -0.015 per day, P < 0.001). The estimated rate ratio comparing incidence rates at time points 1 month apart was 0.632 (95% confidence interval, 0.524-0.763). Thus, there was an estimated 37% decline in fall rate per month (95% confidence interval, 24%-48%). Improvements were also observed on the Mini-BESTest (P = 0.037) and FES-I (P = 0.059). DISCUSSION AND CONCLUSIONS: The results of this study show that a theory-based, highly challenging, and progressive exercise program was effective in reducing falls, improving balance, and reducing fear of falling in PD.Video abstract available for more insights from the authors (see Supplemental Digital Content 1, http://links.lww.com/JNPT/A120). TRIAL REGISTRATION: ClinicalTrials.gov NCT02302144.This study was funded by the Boston Claude D. Pepper Older Americans Independence Center (NIH 5P30AG031679). Additional support was provided by the American Parkinson Disease Association (ADPA); ADPAMA Chapter. (NIH 5P30AG031679 - Boston Claude D. Pepper Older Americans Independence Center; American Parkinson Disease Association (ADPA); ADPAMA Chapter

    Progression from ocular hypertension to visual field loss in the English hospital eye service

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    Background There are more than one million National Health Service visits in England and Wales each year for patients with glaucoma or ocular hypertension (OHT). With the ageing population and an increase in optometric testing, the economic burden of glaucoma-related visits is predicted to increase. We examined the conversion rates of OHT to primary open-angle glaucoma (POAG) in England and assessed factors associated with risk of conversion. Methods Electronic medical records of 45 309 patients from five regionally different glaucoma clinics in England were retrospectively examined. Conversion to POAG from OHT was defined by deterioration in visual field (two consecutive tests classified as stage 1 or worse as per the glaucoma staging system 2). Cox proportional hazards models were used to examine factors (age, sex, treatment status and baseline intraocular pressure (IOP)) associated with conversion. Results The cumulative risk of conversion to POAG was 17.5% (95% CI 15.4% to 19.6%) at 5 years. Older age (HR 1.35 per decade, 95% CI 1.22 to 1.50, p<0.001) was associated with a higher risk of conversion. IOP-lowering therapy (HR 0.45, 95% CI 0.35 to 0.57, p<0.001) was associated with a lower risk of conversion. Predicted 5-year conversion rates for treated and untreated groups were 14.0% and 26.9%, respectively. Conclusion Less than one-fifth of OHT patients managed in glaucoma clinics in the UK converted to POAG over a 5-year period, suggesting many patients may require less intensive follow-up. Our study provides real-world evidence for the efficacy of current management (including IOP-lowering treatment) at reducing risk of conversion

    Direct transition to high-dimensional chaos through a global bifurcation

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    In the present work we report on a genuine route by which a high-dimensional (with d>4) chaotic attractor is created directly, i.e., without a low-dimensional chaotic attractor as an intermediate step. The high-dimensional chaotic set is created in a heteroclinic global bifurcation that yields an infinite number of unstable tori.The mechanism is illustrated using a system constructed by coupling three Lorenz oscillators. So, the route presented here can be considered a prototype for high-dimensional chaotic behavior just as the Lorenz model is for low-dimensional chaos.Comment: 7 page

    Enhancing image contrast using coherent states and photon number resolving detectors

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    We experimentally map the transverse profile of diffraction-limited beams using photon-number-resolving detectors. We observe strong compression of diffracted beam profiles for high detected photon number. This effect leads to higher contrast than a conventional irradiance profile between two Airy disk-beams separated by the Rayleigh criterion.Comment: 7 pages, 3 figures, accepted for publication in Optics Expres

    A Comparison of Treadmill and Overground Walking Effects on Step Cycle Asymmetry in Young and Older Individuals

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    Although lower limb strength becomes asymmetrical with age, past studies of aging effects on gait biomechanics have usually analyzed only one limb. This experiment measured how aging and treadmill surface influenced both dominant and nondominant step parameters in older (mean 74.0 y) and young participants (mean 21.9 y). Step-cycle parameters were obtained from 3-dimensional position/time data during preferred-speed walking for 40 trials along a 10 m walkway and for 10 minutes of treadmill walking. Walking speed (young 1.23 m/s, older 1.24 m/s) and step velocity for the two age groups were similar in overground walking but older adults showed significantly slower walking speed (young 1.26 m/s, older 1.05 m/s) and step velocity on the treadmill due to reduced step length and prolonged step time. Older adults had shorter step length than young adults and both groups reduced step length on the treadmill. Step velocity and length of older adults’ dominant limb was asymmetrically larger. Older adults increased the proportion of double support in step time when treadmill walking. This adaptation combined with reduced step velocity and length may preserve balance. The results suggest that bilateral analyses should be employed to accurately describe asymmetric features of gait especially for older adults

    Longitudinal Laminar Flow Between Cylinders Arranged in Regular Array

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    The increasing complexity of heat transfer and process situations which involve fluid flow has demanded the frequent use of flow passages of unusual geometrical configuration. The present investigation is concerned with one such novel configuration, namely the longitudinal flow between solid cylindrical rods which are arranged in regular array. A schematic diagram of the situation under study. The rods may be located either in triangular or square array. The flow will be taken to be laminar and fully developed. The aim of this analysis is to determine the pressure drop, shear stress, and velocity-distribution characteristics of the system. The starting point of this study is the basic law of momentum conservation. The resulting differential equation has been solved in an approximate, but almost exact, manner by the use of truncated trigonometric series. Results are obtained over a wide range of porosity values for both the triangular and square arrays. Heat transfer has not been considered. The configuration under investigation has potential application in compact heat exchangers for nuclear reactors and other situations. Further the results should also be of interest in the theory of flow through unconsolidated porous beds (ia, 9a). The only related analytical work known to the authors is that of Emersleben (S), who considered only the square array. His rather involved solution, based on complex zeta functions, appears to be valid only at high porosities. Experiments covering a porosity range of 0.093 to 0.984 have been made by Sullivan (4) using parallel-oriented fibers, most of the tests being for fibers in random array. These previous investigations will be compared with the present theory in a later section

    Comparison of X-ray and gamma-ray dose-response curves for pink somatic mutations in Tradescantia clone 02

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    Microdosimetric data indicate that the mean specific energy,zeta, produced by individual charged particles from X rays and gamma rays is different for the two radiation qualities by nearly a factor of two. In order to test whether this influences the initial, linear component in the dose-effect relations, a comparison was made between dose-response curves for pink somatic mutations inTradescantia clone 02 stamen hairs following X and gamma irradiations. Absorbed doses ranged from 2.66 to 300 rad. The results are in agreement with predictions made on the basis of microdosimetric data. At low doses gamma rays are substantially less effective than X rays. The RBE of gamma rays vs. X rays at low doses was approximately 0.6, a value lower than those usually reported in other experimental systems
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