MarsLux: HI-Resolution Illumination Maps Generator for Mars

Illumination simulation codes for the Moon's surface have been thoroughly developed during the last years. Despite works done for the Moon, no studies have investigated the relation between sunlight illumination and the Martian surface applying those codes done for the Moon to Mars. The objective of this work is to describe the development of a surface illumination simulation code, called MarsLux, which allows users to make a detailed investigation of the illumination conditions on Mars, based on its topography and the relative position of the Sun. Our code can derive accurate illumination maps, form topographic data, showing areas that are fully illuminated, areas in total shadow, and areas with partial shade, in short computational times. Although the code does not take into account any atmospheric effect, the results proved to be of high accuracy. The maps generated are useful for geomorphological studies, to study gullies, thermal weathering, or mass wasting processes as well as for producing energy budget maps for future exploration missions.Fil: Spagnuolo, Mauro Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Estudios Andinos "Don Pablo Groeber". Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Estudios Andinos "Don Pablo Groeber"; ArgentinaFil: Carballo, Federico Daniel. Servicio Geologico Minero Argentino; ArgentinaFil: Marco Figuera, R.. Jacobs University Bremen; AlemaniaFil: Rossi, A. P.. Jacobs University Bremen; Alemani

Validation of multi-physics integrated procedure for the HCPB breeding blanket

The wide range of requirements and constraints involved in the design of nuclear components for fusion reactors makes the development of multi-physics analysis procedures of utmost importance. In the framework of the European DEMO project, the Karlsruhe Institute of Technology (KIT) is dedicating several efforts to the development of a multi-physics analysis tool allowing the characterization of breeding blanket design points which are consistent from the neutronic, thermal-hydraulic and thermal-mechanical points of view. In particular, a procedure developed at KIT is characterized by the implementation of analysis software only. A preliminary step for the validation of such a procedure has been accomplished using a dedicated model of the DEMO Helium Cooled Pebble Bed Blanket 4th outboard module. A global model representative of nuclear irradiation in DEMO and two local models have been set up. Nuclear power deposition and the spatial distribution of its volumetric density have been calculated using Monte Carlo N-Particle transport code for the aforementioned models and compared in order to validate the procedure set up. The outcomes of this comparative study are herein presented and critically discussed

Structural assessment of the EU-DEMO water-cooled lead lithium central outboard blanket segment adopting the sub-modelling technique

The development of a sound conceptual design of the Water-Cooled Lead Lithium Breeding Blanket (WCLL BB) is pivotal to make a breakthrough towards the selection of the driver blanket concept for the EU-DEMO. To achieve this goal, an intense research campaign has been performed at the University of Palermo, in cooperation with ENEA Brasimone, under the umbrella of EUROfusion. In this paper, structural analyses of different poloidal regions of the WCLL BB Central Outboard Blanket (COB) segment are reported. In particular, starting from the results of the thermo-mechanical analysis of the whole WCLL BB COB segment, the sub-modelling technique has been applied to the most significant poloidal regions, located at the top, middle and bottom of the segment. The aim is to focus on the stress field locally arising under purposely selected steady-state nominal and accidental loading scenarios. The nominal BB operating conditions, as well as steady-state scenarios derived from both the in-box LOCA and Vertical Plasma Disruption accidents have been considered. Thanks to the sub-modelling approach, the deformative action of the entire segment can be imposed at the boundaries of each local model to realistically assess its structural performances. Moreover, each local model reproduces structural details not included in the global one, such as the Segment Box (SB) cooling channels. Then, the structural behaviour of the selected regions has been assessed in compliance with the RCC-MRx code. The obtained results highlighted that the structural behaviour predicted by the whole segment analysis is similar to that predicted by sub-modelling calculations within the Stiffening Plates, whereas the application of the sub-modelling is a must to investigate in detail the SB structural performances. In addition, results indicate that the BB attachments should be revised, as they contribute to produce the WCLL COB large deformation originating excessive stresses, mainly within the equatorial region

Age estimation based on pulp–tooth volume ratio of anterior teeth in cone-beam computed tomographic images in a selected population: A cross-sectional study

The present study aimed to investigate the correlation between chronological age and pulp– tooth volume ratio in anterior teeth using cone beam computed tomographic (CBCT) images and provide equations for age estimation based on pulp–tooth volume ratio. In this cross-sectional study, CBCT images of 312 anterior teeth of the maxilla and mandible were examineαd. The chronological age and the sex of the patients were recorded. Tooth volume and pulp volume of the anterior teeth were measured using Mimics software, and then tooth–pulp volume ratio was calculated. Statistical analysis of data was performed using chi-square test, independent T-test, Pearson’s correlation, and linear regression (α = 0.05). Finally, equations were made based on the results of the regression analysis for age estimation in general and for males and females. The age of the subjects ranged between 16 and 69 years (mean 40.6 ± 12.74). The pulp–tooth volume ratio of the maxillary teeth was generally higher than the mandibular teeth. A significant inverse relationship between age and pulp–tooth volume ratio was observed for all anterior teeth. (p < 0.05). The strongest correlation between age and pulp–tooth volume ratio was reported for mandibular central incisor (r = −0.58, p < 0.001) and the weakest was for mandibular lateral incisor (r = −0.36, p = 0.012). Age estimation was most accurate among females using the maxillary central incisors (p < 0.001) and among males using the mandibular central incisors and maxillary canines (p = 0.003). Pulp–tooth volume ratio of mandibular central incisors, maxillary lateral incisors, and maxillary canines in males and maxillary and mandibular central incisors, maxillary lateral incisors, and maxillary and mandibular canines in females can be used for age estimation

Minimization of Adverse Effects Associated with Dental Alloys

Metal alloys are one of the most popular materials used in current dental practice. In the oral cavity, metal structures are exposed to various mechanical and chemical factors. Consequently, metal ions are released into the oral fluid, which may negatively affect the surrounding tissues and even internal organs. Adverse effects associated with metallic oral appliances may have various local and systemic manifestations, such as mouth burning, potentially malignant oral lesions, and local or systemic hypersensitivity. However, clear diagnostic criteria and treatment guidelines for adverse effects associated with dental alloys have not been developed yet. The present comprehensive literature review aims (1) to summarize the current information related to possible side effects of metallic oral appliances; (2) to analyze the risk factors aggravating the negative effects of dental alloys; and (3) to develop recommendations for diagnosis, management, and prevention of pathological conditions associated with metallic oral appliances

Effect of glass on the frictional behavior of basalts at seismic slip rates

We performed 31 friction experiments on glassy basalts (GB) and glass-free basalts (GFB) at slip rates up to 6.5 m s−1 and normal stress up to 40 MPa (seismic conditions). Frictional weakening was associated to bulk frictional melting and lubrication. The weakening distance (Dw) was about 3 times shorter in GB than in GFB, but the steady state friction was systematically higher in GB than in GFB. The shorter Dw in GB may be explained by the thermal softening occurring at the glass transition temperature (Tg ~500°C), which is lower than the bulk melting temperature (Tm ~1250°C) of GFB. Postexperiment microanalyses suggest that the larger crystal fraction measured in GB melts results in the higher steady state friction value compared to the GFB melts. The effect of interstitial glass is to facilitate frictional instability and rupture propagation in GB with respect to GFB

LCAT cholesterol esterification is associated with the increase of ApoE/ApoA-I ratio during atherosclerosis progression in rabbit

Apolipoprotein A-I and Apolipoprotein E promote different steps of reverse cholesterol transport, including lecithin-cholesterol acyltransferase stimulation. Our aim was to study the changes in the levels of Apolipoprotein A-I, Apolipoprotein E, and lecithin-cholesterol acyltransferase activity during atherosclerosis progression in rabbits. Quantitative echocardiographic parameters were analyzed in order to evaluate, for the first time, whether atherosclerosis progression in rabbit is associated to apolipoproteins changes and alteration of indices of cardiac function, such as systolic strain and strain rate of the left ventricle. Atherosclerosis was induced by feeding rabbits for 8 weeks with 2 % cholesterol diet. The HDL levels of cholesterol and cholesteryl esters were measured by HPLC. The lecithin-cholesterol acyltransferase activity was evaluated both ex vivo, as cholesteryl esters/cholesterol molar ratio, and in vitro. Apolipoproteins levels were analyzed by ELISA. The HDL levels of cholesterol and cholesteryl esters increased, during treatment, up to 3.7- and 2.5-fold, respectively, compared to control animals. The lecithin-cholesterol acyltransferase activity in vitro was halved after 4 weeks. During cholesterol treatment, Apolipoprotein A-I level significantly decreased, whereas Apolipoprotein E concentration markedly increased. The molar ratio Apolipoprotein E/Apolipoprotein A-I was negatively correlated with the enzyme activity, and positively correlated with both increases in the intima-media thickness of common carotid wall and cardiac dysfunction signs, such as systolic strain and strain rate of the left ventricle. © 2012 University of Navarra

Comparison of antimicrobial and wound-healing effects of silver nanoparticle and chlorhexidine mouthwashes: an in vivo study in rabbits

The objective is to formulate a silver nanoparticle mouthwash and then evaluate its antimicrobial and wound-healing effects in rabbit animal models. Microbial samples were collected from the oral cavity of 60 rabbits. Thereafter, standardized wounds were created in the lateral border of the tongue on the right side for all rabbits. After surgery, digital photographs were obtained from the wounds with standardized settings. To characterize the silver nanoparticles used in the synthetic mouthwash, transmission electron microscopy (TEM) and digital light scattering analysis were used. The animal models were then randomly divided into 4 groups: group 1 received 9.80 wt% silver nanoparticle mouthwash; group 2 received all the ingredients of the formulated mouthwash except for silver nanoparticles; group 3 received chlorhexidine 2.0% mouthwash; and the negative control group did not receive any postoperative mouthwash. Microbial samples were collected from oral cavity of the rabbits each day for four postoperative days. Colony-forming unit (CFU) counts were compared post-operatively with the pre-operative counts. In addition, standardized digital photographs were taken each day from the wounds and the area of the wounds was compared in postoperative and pre-operative images. Data were statistically analyzed using one-way ANOVA and repeated measures variance analysis (α = 0.05). TEM revealed spherical morphology of silver nanoparticles and digital light scattering showed an average size of 5 nm and optimal distribution of the nanoparticles. CFU count significantly decreased in groups 1 and 3 (P 0.05). Silver nanoparticle mouthwash possesses favorable antibacterial and wound-healing effects. The formulated 9.80 wt% silver nanoparticle mouthwash with a particle size of 5 nm can be a promising alternative for application after oral surgical procedures

LCAT cholesterol esterification is associated with the increase of ApoE/ApoA-I ratio during atherosclerosis progression in rabbit

Apolipoprotein A-I and Apolipoprotein E promote different steps of reverse cholesterol transport, including lecithin-cholesterol acyltransferase stimulation. Our aim was to study the changes in the levels of Apolipoprotein A-I, Apolipoprotein E, and lecithin-cholesterol acyltransferase activity during atherosclerosis progression in rabbits. Quantitative echocardiographic parameters were analyzed in order to evaluate, for the first time, whether atherosclerosis progression in rabbit is associated to apolipoproteins changes and alteration of indices of cardiac function, such as systolic strain and strain rate of the left ventricle. Atherosclerosis was induced by feeding rabbits for 8 weeks with 2 % cholesterol diet. The HDL levels of cholesterol and cholesteryl esters were measured by HPLC. The lecithin-cholesterol acyltransferase activity was evaluated both ex vivo, as cholesteryl esters/cholesterol molar ratio, and in vitro. Apolipoproteins levels were analyzed by ELISA. The HDL levels of cholesterol and cholesteryl esters increased, during treatment, up to 3.7- and 2.5-fold, respectively, compared to control animals. The lecithin-cholesterol acyltransferase activity in vitro was halved after 4 weeks. During cholesterol treatment, Apolipoprotein A-I level significantly decreased, whereas Apolipoprotein E concentration markedly increased. The molar ratio Apolipoprotein E/Apolipoprotein A-I was negatively correlated with the enzyme activity, and positively correlated with both increases in the intima-media thickness of common carotid wall and cardiac dysfunction signs, such as systolic strain and strain rate of the left ventricle. © 2012 University of Navarra