1,728 research outputs found
Agent-oriented Modeling for Collaborative Learning Environments: A Peer-to-Peer Helpdesk Case Study
In this paper, we present the analysis and modelling of Help&Learn, an agent-based peer-to-peer helpdesk system to support extra-class interactions among students and teachers. Help&Learn expands the student’s possibility of solving problems, getting involved in a cooperative learning experience that transcends the limits of classrooms. To model Help&Learn, we have used Agent-Object-Relationship Modeling Language (AORML), an UML extension for agent-oriented information systems modeling. The aim of this research is two-fold. On one hand, we aim at modeling the variety of roles and the complexity of their interactions and activities within the Help&Learn system. On the other hand, we aim at showing the expressive power and the modeling strengths of AORML
Didactic principles and methods of developmental training AT a transitional AGE = Дидактические принципы и методы развивающего обучения в переходном возрасте
The present article aims to share the results obtained by the investigation of how the Developmental Didactics can help the organization of the teaching of Sociology aiming at promoting the full development of students in transition phase. It was carried out through a Didactic- Formative Intervention, in a Brazilian public school in the city of Uberlândia-MG, in high school classes and constituted by adolescent students. From this investigative effort, didactic principles emerged that aim to guide the organization of a teaching that aims at the simultaneous development of the teacher and the students in the relationships they establish in the classroom through pedagogical practice
Sustainable Practices Improving the University Campus: Feasibility of A Photovoltaic System
This article aimed to discuss the principles of sustainability applied to the built environment, highlighting the importance of universities as replicators of these practices. To respond to a demand from the campus for more security in the energy supply, the work proposes the implementation of a solar photovoltaic energy system. For this, it carried out an economic viability analysis through bibliographic review activities, characterization of the study area, dimensioning of photovoltaic systems, budgets, cost analysis and payback calculation. The research evaluated the system’s implementation considering two energy demands, for the entire campus and for a smaller building. It was found that the CSL-UFSJ consumes, on average, 27,300.38 kWh, at a cost of US 32,833 is calculated. The cost estimate analyzes showed a value of US 1,322 per month, which results in an annual savings of US 40.601 for the implementation of the system and values of 4.3 and 4.9 years were obtained as return on investment time considering the calculations for simple and discounted Payback, respectively. The research demonstrates that the implementation of the photovoltaic solar energy generation system is feasible for both cases analyzed.
Fischer-Tropsch synthesis in microchannels
Different metallic supports (aluminum foams of 40ppi, honeycomb monolith and micromonolith of 350 and 1180cpsi, respectively) have been loaded with a 20%Co-0.5%Re/γ-Al2O3 catalyst by the washcoating method. Layers of different thicknesses have been deposited onto the metallic supports. The catalytic coatings were characterized measuring their textural properties, adhesion and morphology. These structured catalysts have been tested in the Fischer-Tropsch synthesis (FTS) and compared with a microchannel block presenting perpendicular channels for reaction and cooling. The selectivity depends on the type of support used and mainly on the thickness of the layer deposited. In general, the C5+ selectivity decreased at increasing CO conversion for all of the systems (powder, monoliths, foams and microchannels block). On the other hand, the selectivity to methane increased with the thickness of the catalytic layer due to the higher effective H2/CO ratio over the active sites resulting from the higher diffusivity of H2 compared with CO in the liquid products filling the pores. The C5+ selectivity of the microchannels reactor is higher than that of the structured supports and the powder catalyst.Ministerio de Ciencia e Innovación MAT2006-12386-C05, ENE2009-14522-C0
Composição corporal e perfil metabólico na deficiência de vitamina D sérica em adultos
sem informaçãoTo investigate the body composition and metabolic profile in individuals in terms of different concentrations of serum vitamin D, ranging from deficiency to sufficiency. A cross-sectional study of 106 adults of both genders, who were divided into three g304419430sem informaçãosem informaçãosem informaçã
The Second Step In The Construction Of A Stigma Scale Of Epilepsy
Rationale: The issue of stigmatization is one of the most common psychosocial problems faced by people with epilepsy. Purpose: A second step towards the development of a scale to measure epilepsy stigma. Method: We applied a closed questionnaire to 12 patients and 32 relatives from the Epilepsy Outpatient Clinic at the University Hospital of Campinas. Results: The results are grouped in three main domains: medical, social and personal areas. Medical: the subjects did not know exactly what epilepsy is or how it is caused; nonetheless they know how to treat it. Social: the most important areas that people with epilepsy are discriminated are at work and social relationships. Patients also complained about their lack of freedom and limits on recreation activities. Personal Area: subjects apparently have the same feelings and thoughts about epilepsy and seizures. Conclusion: This study analyzed the most common aspects presented in the questionnaire to assess epilepsy stigma for the Brazilian culture which are the base to the elaboration of a stigma scale of epilepsy.632 B395398Fernandes, P.T., Souza, E.A., Identification of family variables in parents' groups of children with epilepsy (2001) Arq Neuropsiquiatr, 59, pp. 854-858Li, L.M., Sander, J.W., National demonstration project on epilepsy in Brazil (2003) Arq Neuropsiquiatr, 61, pp. 153-156Leidy, N.K., Rentz, A.M., Grace, E.M., Evaluating health-related quality of life outcomes in clinical trials of antiepileptic drug therapy (2004) Epilepsia, 39, pp. 965-977Baker, G.A., Brooks, J., Buck, D., Jacoby, A., The stigma of epilepsy: A European perspective (2000) Epilepsia, 41, pp. 98-104Baker, G.A., Nashef, L., Van Hout, B.A., Current issues in the management of epilepsy: The impact of frequent seizures on cost of illness, quality of life, and mortality (1997) Epilepsia, 38 (SUPPL. 1), pp. S1-S8Baker, G.A., Jacoby, A., Chadwick, D.W., The associations of psychopathology in epilepsy: A community study (1996) Epilepsy Res, 25, pp. 29-39Jacoby, A., Felt versus enacted stigma: A concept revisited. Evidence from a study of people with epilepsy in remission (1994) Soc Sci Med, 38, pp. 269-274Placencia, M., Farmer, P.J., Jumbo, L., Sander, J.W., Shorvon, S.D., Levels of stigmatization of patients with previously untreated epilepsy in northern Ecuador (1995) Neuroepidemiology, 14, pp. 147-154Ratsepp, M., Oun, A., Haldre, S., Kaasik, A.E., Felt stigma and impact of epilepsy on employment status among Estonian people: Exploratory study (2000) Seizure, 9, pp. 394-401Scambler, G., Hopkins, A., Generating a model of epileptic stigma: The role of qualitative analysis (1990) Soc Sci Med, 30, pp. 1187-1194Ryan, R., Kempner, K., Emlen, A.C., The stigma of epilepsy as a self-concept (1980) Epilepsia, 21, pp. 433-444Fernandes, P.T., Salgado, P.C., Ala, N., Barbosa, F.D., Souza, E.A., Li, L.M., Stigma Scale of Epilepsy: Conceptual issues (2004) J Epilep Clin Neuropshysiology, 10, pp. 213-218McLin, W.M., De Boer, H.M., Public perceptions about epilepsy (1995) Epilepsia, 36, pp. 957-95
A study of the bound states for square potential wells with position-dependent mass
A square potential well with position-dependent mass is studied for bound
states. Applying appropriate matching conditions, a transcendental equation is
derived for the energy eigenvalues. Numerical results are presented graphically
and the variation of the energy of the bound states are calculated as a
function of the well-width and mass.Comment: To appear in Phys. Lett. A (Present e-mail of A.G:
[email protected]
A Palatable Hyperlipidic Diet Causes Obesity and Affects Brain Glucose Metabolism in Rats
Background
We have previously shown that either the continuous intake of a palatable hyperlipidic diet (H) or the alternation of chow (C) and an H diet (CH regimen) induced obesity in rats. Here, we investigated whether the time of the start and duration of these feeding regimens are relevant and whether they affect brain glucose metabolism.
Methods
Male Wistar rats received C, H, or CH diets during various periods of their life spans: days 30-60, days 30-90, or days 60-90. Experiments were performed the 60th or the 90th day of life. Rats were killed by decapitation. The glucose, insulin, leptin plasma concentration, and lipid content of the carcasses were determined. The brain was sliced and incubated with or without insulin for the analysis of glucose uptake, oxidation, and the conversion of [1-14C]-glucose to lipids.
Results
The relative carcass lipid content increased in all of the H and CH groups, and the H30-60 and H30-90 groups had the highest levels. Groups H30-60, H30-90, CH30-60, and CH30-90 exhibited a higher serum glucose level. Serum leptin increased in all H groups and in the CH60-90 and CH30-90 groups. Serum insulin was elevated in the H30-60, H60-90, CH60-90, CH30-90 groups. Basal brain glucose consumption and hypothalamic insulin receptor density were lower only in the CH30-60 group. The rate of brain lipogenesis was increased in the H30-90 and CH30-90 groups.
Conclusion
These findings indicate that both H and CH diet regimens increased body adiposity independent treatment and the age at which treatment was started, whereas these diets caused hyperglycemia and affected brain metabolism when started at an early age
The Atp-dependent Rna Helicase Hrpb Plays An Important Role In Motility And Biofilm Formation In Xanthomonas Citri Subsp. Citri
Background: RNA helicases are enzymes that catalyze the separation of double-stranded RNA (dsRNA) using the free energy of ATP binding and hydrolysis. DEAD/DEAH families participate in many different aspects of RNA metabolism, including RNA synthesis, RNA folding, RNA-RNA interactions, RNA localization and RNA degradation. Several important bacterial DEAD/DEAH-box RNA helicases have been extensively studied. In this study, we characterize the ATP-dependent RNA helicase encoded by the hrpB (XAC0293) gene using deletion and genetic complementation assays. We provide insights into the function of the hrpB gene in Xanthomonas citri subsp. citri by investigating the roles of hrpB in biofilm formation on abiotic surfaces and host leaves, cell motility, host virulence of the citrus canker bacterium and growth in planta. Results: The hrpB gene is highly conserved in the sequenced strains of Xanthomonas. Mutation of the hrpB gene (Δ;hrpB) resulted in a significant reduction in biofilms on abiotic surfaces and host leaves. Δ;hrpB also exhibited increased cell dispersion on solid medium plates. Δ;hrpB showed reduced adhesion on biotic and abiotic surfaces and delayed development in disease symptoms when sprayed on susceptible citrus leaves. Quantitative reverse transcription-PCR assays indicated that deletion of hrpB reduced the expression of four type IV pili genes. The transcriptional start site of fimA (XAC3241) was determined using rapid amplification of 5′-cDNA Ends (5′RACE). Based on the results of fimA mRNA structure predictions, the fimA 5′ UTR may contain three different loops. HrpB may be involved in alterations to the structure of fimA mRNA that promote the stability of fimA RNA. Conclusions: Our data show that hrpB is involved in adherence of Xanthomonas citri subsp. citri to different surfaces. In addition, to the best of our knowledge, this is the first time that a DEAH RNA helicase has been implicated in the regulation of type IV pili in Xanthomonas. © 2016 Granato et al.16
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