Comeback of measles through the border with Venezuela: Controversies between resistance and acceptability

The comeback of measles in Brazil through the border with Venezuela has become a social issue. This article makes interdisciplinary reflections about the respective health systems and the polynomial vulnerability/violation/resistance/acceptability within the context of the border region in question. Among the considerations, it is highlighted the success of the Immunization National Program to eradicate measles in Brazil and the fragility of the political and health systems from both countries under analysis regarding border regions mainly in crisis situations. Finally, it is argued that education is the coherent way for the construction of a nation aware of its individual rights and collective duties and that appreciates social policies as they must be respected and valued by the government itself. Thus, herein is an alert on how anti-vaccination movements contribute adversely in the eradication of diseases that can be controlled through more efficacy of vaccination campaigns. &nbsp

EVIDÊNCIAS CIENTÍFICAS DE ENFERMAGEM ACERCA DO HIV/AIDS ENTRE IDOSOS

Nas últimas décadas, mudanças no perfil da epidemia da Síndrome da Imunodeficiência Adquirida têm ocorrido. Uma delas é o aumento da incidência da infecção por HIV entre idosos. Este estudo teve por objetivo levantar as produções científicas de enfermagem sobre HIV/AIDS na população idosa nos últimos dez anos e discutir as evidências que perpassam as produções científicas encontradas. Realizou-se uma revisão integrativa de literatura por intermédio das bases de dados LILACS, SciELO e BDENF, com seleção final de 21 artigos. Com base nesses artigos, foram criadas três categorias: implicações diagnósticas, dificuldades e facilidades a adesão à terapia antirretroviral e ações de Enfermagem. As evidências mostraram que são necessárias habilidades para lidar com as questões relacionadas ao envelhecimento, complexidade do tratamento antirretroviral e eventos adversos, que são as principais causas de abandono à terapêutica. Conclui-se que o papel do Enfermeiro é fundamental no acolhimento e na avaliação integral do idoso

An ELISA to Detect Antibodies to Bovine Alphaherpesviruses 1 and 5 and Bubaline Alphaherpesvirus 1 in Cattle Sera

Bovine alphaherpesvirus 1 (subtypes 1.1, 1.2a, and 1.2b), type 5 (subtypes 5a, 5b, and 5c), and bubaline herpesvirus 1 (BuHV-1) induce highly, though not fully cross-reactive serological responses. Most types and subtypes of these viruses circulate particularly in countries of the southern hemisphere, notably Brazil and Argentina. Therefore, the detection of infected animals is important in defining prevention and control strategies, particularly when flocks are destined for international trade. Identification of infected herds is most often achieved by assays that detect antibodies, such as enzyme immunoassays (ELISAs). However, to date, no ELISA has been evaluated in its capacity to detect antibodies to these alphaherpesviruses. Here, an ELISA was developed to detect antibodies to all currently recognized BoAHV-1, BoAHV-5, and BuAHV-1 types/subtypes, and its sensitivity and specificity were determined. Six hundred bovine sera were screened in serum neutralization tests (SN) against the seven viruses. ELISAs prepared with each of the viruses were compared to SN. Subsequently, a combined assay with multiple antigens LISA was prepared by mixing five viral antigens, chosen for their highest sensitivity in the preparative assays. In comparison to SN, the mAgELISA sensitivity was 96.5% with 96.1% specificity (κ = 0.93; PPV = 95.0%; NPV = 97.3%). The findings reveal that the mAgELISA developed here is highly suitable for the detection of antibodies, comparable in sensitivity and specificity to that of SN when performed with all known types and subtypes of bovine and bubaline alphaherpesviruses

An ELISA to detect antibodies to bovine alphaherpesviruses 1 and 5 and bubaline alphaherpesvirus 1 in cattle sera

Bovine alphaherpesvirus 1 (subtypes 1.1, 1.2a, and 1.2b), type 5 (subtypes 5a, 5b, and 5c), and bubaline herpesvirus 1 (BuHV-1) induce highly, though not fully cross-reactive serological responses. Most types and subtypes of these viruses circulate particularly in countries of the southern hemisphere, notably Brazil and Argentina. Therefore, the detection of infected animals is important in defining prevention and control strategies, particularly when flocks are destined for international trade. Identification of infected herds is most often achieved by assays that detect antibodies, such as enzyme immunoassays (ELISAs). However, to date, no ELISA has been evaluated in its capacity to detect antibodies to these alphaherpesviruses. Here, an ELISA was developed to detect antibodies to all currently recognized BoAHV-1, BoAHV-5, and BuAHV-1 types/subtypes, and its sensitivity and specificity were determined. Six hundred bovine sera were screened in serum neutralization tests (SN) against the seven viruses. ELISAs prepared with each of the viruses were compared to SN. Subsequently, a combined assay with multiple antigens LISA was prepared by mixing five viral antigens, chosen for their highest sensitivity in the preparative assays. In comparison to SN, the mAgELISA sensitivity was 96.5% with 96.1% specificity (κ = 0.93; PPV = 95.0%; NPV = 97.3%). The findings reveal that the mAgELISA developed here is highly suitable for the detection of antibodies, comparable in sensitivity and specificity to that of SN when performed with all known types and subtypes of bovine and bubaline alphaherpesviruses

An ELISA to Detect Antibodies to Bovine Alphaherpesviruses 1 and 5 and Bubaline Alphaherpesvirus 1 in Cattle Sera

Bovine alphaherpesvirus 1 (subtypes 1.1, 1.2a, and 1.2b), type 5 (subtypes 5a, 5b, and 5c), and bubaline herpesvirus 1 (BuHV-1) induce highly, though not fully cross-reactive serological responses. Most types and subtypes of these viruses circulate particularly in countries of the southern hemisphere, notably Brazil and Argentina. Therefore, the detection of infected animals is important in defining prevention and control strategies, particularly when flocks are destined for international trade. Identification of infected herds is most often achieved by assays that detect antibodies, such as enzyme immunoassays (ELISAs). However, to date, no ELISA has been evaluated in its capacity to detect antibodies to these alphaherpesviruses. Here, an ELISA was developed to detect antibodies to all currently recognized BoAHV-1, BoAHV-5, and BuAHV-1 types/subtypes, and its sensitivity and specificity were determined. Six hundred bovine sera were screened in serum neutralization tests (SN) against the seven viruses. ELISAs prepared with each of the viruses were compared to SN. Subsequently, a combined assay with multiple antigens LISA was prepared by mixing five viral antigens, chosen for their highest sensitivity in the preparative assays. In comparison to SN, the mAgELISA sensitivity was 96.5% with 96.1% specificity (κ = 0.93; PPV = 95.0%; NPV = 97.3%). The findings reveal that the mAgELISA developed here is highly suitable for the detection of antibodies, comparable in sensitivity and specificity to that of SN when performed with all known types and subtypes of bovine and bubaline alphaherpesviruses

Analysis of deaths occurred in households during the pandemic by COVID-19 in a Brazilian Amazon Region: an epidemiological approach

Universidade do Estado do Pará. Programa de Pós-Graduação em Biologia Parasitária na Amazônia. Belém, PA, Brasil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Programa de Pós-Graduação em Epidemiologia e Vigilância em Saúde. Ananindeua, PA, Brasil.Secretaria de Saúde do Estado do Pará. Belém, PA, Brazil.Secretaria de Saúde do Estado do Pará. Belém, PA, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Laboratório de Geoprocessamento. Ananindeua, PA, Brasil.Universidade do Estado do Pará. Programa de Pós-Graduação em Biologia Parasitária na Amazônia. Belém, PA, Brasil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Programa de Pós-Graduação em Epidemiologia e Vigilância em Saúde. Ananindeua, PA, Brasil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Programa de Pós-graduação em Pesquisa Clínica em Doenças Infecciosas. Rio de Janeiro, RJ, Brazil.Universidade Federal Rural da Amazônia. Belém, PA, Brazil.Universidade Federal Rural da Amazônia. Belém, PA, Brazil.Secretaria de Saúde do Estado do Pará. Belém, PA, Brazil.Universidade do Estado do Pará. Programa de Pós-Graduação em Biologia Parasitária na Amazônia. Belém, PA, Brasil / Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.In the absence of an analysis of deaths at home from an epidemiological perspective, this study aims to analyze and describe the epidemiological profile of deaths at home assessed by the Death Ceremony Service (DCS) during the SARS-CoV-2 pandemic in the metropolitan region of the Brazilian Amazon, Belém do Pará. A descriptive, quantitative, secondary-based study based on the databases of the Mortality Information System (SIM), referring to the deaths that occurred from March 1 to March 27 June 2020. The variables worked were related to the profile and the causes in the death certificate. The causes of home deaths in 2019 were used to compare with 2020. In the indicated period, 1,203 deaths occurred, an increase of 454% in relation to 2019. The male gender (57.30%), the age group of 60+ (80.80%) and brown race (77.70%) were the most frequent. The main cause of death Acute myocardial infarction (15.05%) followed by COVID-19 (10.29%). During the pandemic, the majority of home deaths were not directly caused by COVID-19, however, they were influenced by it due to the need for social isolation, with the impossibility of obtaining the proper diagnosis or proper treatment, due to the impossibility of on-site care or lack of immediate response

Zygmunt Bauman e a Modernidade Líquina

<p>Esse seminário tem como objetivo enfatizar a importância dos pensamentos de Zygmunt Bauman para o ensino no curso de graduação em enfermagem.</p&gt

Comparison of Muscle Strength, Aerobic Capacity and Body Composition between Healthy Adolescents and Those Living with HIV: A Systematic Review and Meta-Analysis

Background: The adverse effects of antiretroviral therapy associated with complications generated by human immunodeficiency virus (HIV) promote impairments in physical fitness in adolescents. Objective: To analyze the aerobic capacity, muscle strength, and body composition of adolescents living with HIV compared with a healthy population of the same age. Methods: Searches were performed in the MEDLINE, Embase, Web of Science, Scopus and SportDiscus databases until September 2019 and updated in April 2020. Eligibility Criteria: adolescents of both sexes in the age group from 10 to 19 years; living with HIV; cross-sectional, case–control, cohort studies; comparing with a healthy population. Mean differences and 95% Confidence intervals (CIs) were calculated using RevMan (software for systematic reviews). Results: Five articles were included, involving 197 adolescents living with HIV (16 to 18 years) and 185 without infection (13 to 18 years), with the sample in each study ranging from 15 to 65 adolescents. Aerobic capacity and muscle strength were reduced in adolescents with HIV, and body mass index was also significantly lower in this group. Conclusion: Adolescents living with HIV have impaired cardiorespiratory fitness, muscle strength, and body composition when compared to their uninfected peers. However, this systematic review provides limited evidence on the differences between the physical fitness outcomes of adolescents living with HIV compared to healthy adolescents