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    Generalized Heisenberg algebras and k-generalized Fibonacci numbers

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    It is shown how some of the recent results of de Souza et al. [1] can be generalized to describe Hamiltonians whose eigenvalues are given as k-generalized Fibonacci numbers. Here k is an arbitrary integer and the cases considered by de Souza et al. corespond to k=2.Comment: 8 page

    João Carlos Souza

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    Gibran de Souza

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    Heitor Villa-LobosJoaquin RodrigoAaron Jay KernisSamuel AdlerEgberto GismontiDilermando Reis, arr. Edson LopesDilermando Reis, arr. Jair TeodoroArmando Neves, arr. Edson Lope

    Germano José de Souza

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    O presente artigo discorre sobre uma visão holística das Universidades sobre o ensino superior no Brasil, através do Programa “Universidade para Todos - ProUni. Tem como principal tema estabelecer cotas de bolsas de estudos, para a inclusão de alunos carentes, provenientes de escolas públicas e privadas, em troca de isenção fiscal. As referidas cotas, além de atender os alunos carentes, também favorecem a classe da raça negra, indígena e portadores de necessidades especiais. O objetivo principal do artigo é apontar uma relação histórica comparativa, demonstrando inicialmente, uma total exclusão dos mesmos na Universidade

    What cases on lean hospital transformation tell us?

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    The scientific knowledge about the lean transformation of hospital processes is at best in its “emerging” phase; neither related international, nor Hungarian literature offers a systematic, comprehensive description of the phenomenon (Brandao de Souza, 2009). In this paper empirical evidences concerning the lean transformation of hospital processes are researched and systemized. Thus it provides a new insight of existing knowledge in order to provide solid base for further researches and practical actions

    Interview with Mary Souza

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    A seventy-two-year-old retired substitute schoolteacher discusses her childhood experiences in Kalihi Valley.substitute school teacher; Portuguese; femaleInterview conducted in English.Stat

    Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue

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    In response to cold, norepinephrine (NE)-induced triacylglycerol hydrolysis (lipolysis) in adipocytes of brown adipose tissue (BAT) provides fatty acid substrates to mitochondria for heat generation (adaptive thermogenesis). NE-induced lipolysis is mediated by protein kinase A (PKA)-dependent phosphorylation of perilipin, a lipid droplet-associated protein that is the major regulator of lipolysis. We investigated the role of perilipin PKA phosphorylation in BAT NE-stimulated thermogenesis using a novel mouse model in which a mutant form of perilipin, lacking all six PKA phosphorylation sites, is expressed in adipocytes of perilipin knockout (Peri KO) mice. Here, we show that despite a normal mitochondrial respiratory capacity, NE-induced lipolysis is abrogated in the interscapular brown adipose tissue (IBAT) of these mice. This lipolytic constraint is accompanied by a dramatic blunting (∼70%) of the in vivo thermal response to NE. Thus, in the presence of perilipin, PKA-mediated perilipin phosphorylation is essential for NE-dependent lipolysis and full adaptive thermogenesis in BAT. In IBAT of Peri KO mice, increased basal lipolysis attributable to the absence of perilipin is sufficient to support a rapid NE-stimulated temperature increase (∼3.0°C) comparable to that in wild-type mice. This observation suggests that one or more NE-dependent mechanism downstream of perilipin phosphorylation is required to initiate and/or sustain the IBAT thermal response

    Roberto de Souza Salgado

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