506 research outputs found

    Terahertz response of patterned epitaxial graphene

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    We study the interaction between polarized terahertz (THz) radiation and micro-structured large-area graphene in transmission geometry. In order to efficiently couple the radiation into the two-dimensional material, a lateral periodic patterning of a closed graphene sheet by intercalation doping into stripes is chosen. We observe unequal transmittance of the radiation polarized parallel and perpendicular to the stripes. The relative contrast, partly enhanced by Fabry-Perot oscillations reaches 20 %. The effect even increases up to 50 % when removing graphene stripes in analogy to a wire grid polarizer. The polarization dependence is analyzed in a large frequency range from < 80 GHz to 3 THz, including the plasmon-polariton resonance. The results are in excellent agreement with theoretical calculations based on the electronic energy spectrum of graphene and the electrodynamics of the patterned structureThe authors thank J. Jobst for fruitful discussions. The research was performed in the framework of the Sonderforschungsbereich 953 "Synthetic carbon allotropes", funded by Deutsche Forschungsgemeinschaft. We acknowledge support from the EC under Graphene Flagship (contract no. CNECT-ICT-604391)

    Microscale channels produced by micro friction stir channeling (μFSC)

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    Funding Information: The authors acknowledge the Foundation for Science and Technology ( FCT - MCTES) for its financial support via the projects UIDB/00667/2020 and UIDP/00667/2020 ( UNIDEMI ). Funding Information: The authors acknowledge the Foundation for Science and Technology (FCT - MCTES) for its financial support via the projects UIDB/00667/2020 and UIDP/00667/2020 (UNIDEMI). We also thank the Federal Institute of Education, Science, and Technology of S\u00E3o Paulo for providing its infrastructure to produce the tools used in this research and carry out part of the \u03BCFSC tests. The authors would like to thank the Nuclear and Energy Research Institute (IPEN) in S\u00E3o Paulo, Brazil, and its researchers Ph.D. Marco A. Stanojev Pereira for the neutron tomography images obtained and Ph.D. Stela M. C. Fernandes for the optical microscopy images. Publisher Copyright: © 2024 The AuthorsThe current literature lacks comprehensive research on the processing limits of the Friction Stir Channeling process (FSC) for creating the smallest continuous and integral channels, using tools with threaded probes 2 mm in diameter or smaller. This study pioneers the exploration of the extreme limits of the microscale FSC process, with potential applications in the development of ultra-compact heat exchangers, seeking to enhance the efficiency and sustainability of these systems. Customized tools were designed and manufactured, with predefined dimensions and geometries to establish a set of parameters that consistently produce continuous microchannels, maximizing the hydraulic diameter within the constraints of each tool's specifications and geometry. Comprehensive evaluations—including continuity, watertightness, micro-computed tomography, neutron computed tomography, microhardness testing, and thermal measurements—were conducted to ensure the channels' structural integrity and suitability for super-compact heating and cooling applications. Internal channels were successfully created using tools with threaded probes measuring 2.0, 1.0, and 0.5 mm in diameter, and corresponding shoulder diameters of 5, 4, and 3.5 mm, within 5 mm thick AW1050-H111 aluminum alloy plates. The smallest channel achieved a hydraulic diameter of 191 μm, using a 0.5 mm diameter threaded probe, thus qualifying it as a microchannel. The thermal performance of a compact heat exchanger model was also tested, demonstrating that despite the high cost associated with tool production, particularly due to the specialized manufacturing processes required, the FSC process remains viable, reliable, and repeatable for the production of mini- and micro-channels.publishersversionpublishe

    Small but crucial : the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans

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    Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast

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    Acknowledgments We thank Rebecca Shapiro for creating CaLC1819, CaLC1855 and CaLC1875, Gillian Milne for help with EM, Aaron Mitchell for generously providing the transposon insertion mutant library, Jesus Pla for generously providing the hog1 hst7 mutant, and Cathy Collins for technical assistance.Peer reviewedPublisher PD

    Virasoro constraints in Drinfeld-Sokolov hierarchies

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    We describe a geometric theory of Virasoro constraints in generalized Drinfeld-Sokolov hierarchies. Solutions of Drinfeld-Sokolov hierarchies are succinctly described by giving a principal bundle on a complex curve together with the data of a Higgs field near infinity. String solutions for these hierarchies are defined as points having a big stabilizer under a certain Lie algebra action. We characterize principal bundles coming from string solutions as those possessing connections compatible with the Higgs field near infinity. We show that tau-functions of string solutions satisfy second-order differential equations generalizing the Virasoro constraints of 2d quantum gravity.Comment: 28 page

    Room temperature plasmonic lasing in a continuous wave operation mode from an InGaN/GaN single nanorod with a low threshold

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    It is crucial to fabricate nano photonic devices such as nanolasers in order to meet the requirements for the integration of photonic and electronic circuits on the nanometre scale. The great difficulty is to break down a bottleneck as a result of the diffraction limit of light. Nanolasers on a subwavelength scale could potentially be fabricated based on the principle of surface plasmon amplification by stimulated emission of radiation (SPASER). However, a number of technological challenges will have to be overcome in order to achieve a SPASER with a low threshold, allowing for a continuous wave (cw) operation at room temperature. We report a nano-SPASER with a record low threshold at room temperature, optically pumped by using a cw diode laser. Our nano-SPASER consists of a single InGaN/GaN nanorod on a thin SiO2 spacer layer on a silver film. The nanorod containing InGaN/GaN multi-quantum-wells is fabricated by means of a cost-effective post-growth fabrication approach. The geometry of the nanorod/dielectric spacer/plasmonic metal composite allows us to have accurate control of the surface plasmon coupling, offering an opportunity to determine the optimal thickness of the dielectric spacer. This approach will open up a route for further fabrication of electrically injected plasmonic lasers

    Can we predict real-time fMRI neurofeedback learning success from pretraining brain activity?

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    Neurofeedback training has been shown to influence behavior in healthy participants as well as to alleviate clinical symptoms in neurological, psychosomatic, and psychiatric patient populations. However, many real-time fMRI neurofeedback studies report large inter-individual differences in learning success. The factors that cause this vast variability between participants remain unknown and their identification could enhance treatment success. Thus, here we employed a meta-analytic approach including data from 24 different neurofeedback studies with a total of 401 participants, including 140 patients, to determine whether levels of activity in target brain regions during pretraining functional localizer or no-feedback runs (i.e., self-regulation in the absence of neurofeedback) could predict neurofeedback learning success. We observed a slightly positive correlation between pretraining activity levels during a functional localizer run and neurofeedback learning success, but we were not able to identify common brain-based success predictors across our diverse cohort of studies. Therefore, advances need to be made in finding robust models and measures of general neurofeedback learning, and in increasing the current study database to allow for investigating further factors that might influence neurofeedback learning

    The role of citizen science in addressing grand challenges in food and agriculture research

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    The power of citizen science to contribute to both science and society is gaining increased recognition, particularly in physics and biology. Although there is a long history of public engagement in agriculture and food science, the term ‘citizen science’ has rarely been applied to these efforts. Similarly, in the emerging field of citizen science, most new citizen science projects do not focus on food or agriculture. Here, we convened thought leaders from a broad range of fields related to citizen science, agriculture, and food science to highlight key opportunities for bridging these overlapping yet disconnected communities/fields and identify ways to leverage their respective strengths. Specifically, we show that (i) citizen science projects are addressing many grand challenges facing our food systems, as outlined by the United States National Institute of Food and Agriculture, as well as broader Sustainable Development Goals set by the United Nations Development Programme, (ii) there exist emerging opportunities and unique challenges for citizen science in agriculture/food research, and (iii) the greatest opportunities for the development of citizen science projects in agriculture and food science will be gained by using the existing infrastructure and tools of Extension programmes and through the engagement of urban communities. Further, we argue there is no better time to foster greater collaboration between these fields given the trend of shrinking Extension programmes, the increasing need to apply innovative solutions to address rising demands on agricultural systems, and the exponential growth of the field of citizen science.This working group was partially funded from the NCSU Plant Sciences Initiative, College of Agriculture and Life Sciences ‘Big Ideas’ grant, National Science Foundation grant to R.R.D. (NSF no. 1319293), and a United States Department of Food and Agriculture-National Institute of Food and Agriculture grant to S.F.R., USDA-NIFA Post Doctoral Fellowships grant no. 2017-67012-26999.http://rspb.royalsocietypublishing.orghj2018Forestry and Agricultural Biotechnology Institute (FABI

    Assessment of the capacity to consent to treatment in patients admitted to acute medical wards

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    BACKGROUND: Assessment of capacity to consent to treatment is an important legal and ethical issue in daily medical practice. In this study we carefully evaluated the capacity to consent to treatment in patients admitted to an acute medical ward using an assessment by members of the medical team, the specific Silberfeld's score, the MMSE and an assessment by a senior psychiatrist. METHODS: Over a 3 month period, 195 consecutive patients of an internal medicine ward in a university hospital were included and their capacity to consent was evaluated within 72 hours of admission. RESULTS: Among the 195 patients, 38 were incapable of consenting to treatment (unconscious patients or severe cognitive impairment) and 14 were considered as incapable of consenting by the psychiatrist (prevalence of incapacity to consent of 26.7%). Agreement between the psychiatrist's evaluation and the Silberfeld questionnaire was poor (sensitivity 35.7%, specificity 91.6%). Experienced clinicians showed a higher agreement (sensitivity 57.1%, specificity 96.5%). A decision shared by residents, chief residents and nurses was the best predictor for agreement with the psychiatric assessment (sensitivity 78.6%, specificity 94.3%). CONCLUSION: Prevalence of incapacity to consent to treatment in patients admitted to an acute internal medicine ward is high. While the standardized Silberfeld questionnaire and the MMSE are not appropriate for the evaluation of the capacity to consent in this setting, an assessment by the multidisciplinary medical team concurs with the evaluation by a senior psychiatrist
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