Buoyant Venus station feasibility study. Volume IV - Communications and power Final report

Telecommunication and power supply requirements for inflatable buoyant Venus statio

Development and flight tests of a Kalman filter for navigation during terminal area and landing operations

A Kalman filter for aircraft terminal area and landing navigation was implemented and flight tested in the NASA Ames STOLAND avionics computer onboard a Twin Otter aircraft. This system combines navaid measurements from TACAN, MODILS, air data, radar altimeter sensors along with measurements from strap-down accelerometer and attitude angle sensors. The flight test results demonstrate that the Kalman filter provides improved estimates of the aircraft position and velocity as compared with estimates from the more standard complementary filter. The onboard computer implementation requirements to achieve this improved performance are discussed

Legalized Abortion and the Homicide of Young Children: An Empirical Investigation

Recent research has drawn a link, sometimes a causal link, between the legalization of abortion in the late 1960s and early 1970s and the precipitous decline in crime in the 1990s. Abortion is posited to have reduced the number of potential victims and potential perpetrators, and the potential effect is examined when these individuals would be reaching their high-crime years. We examined a more proximal potential association between legalized abortion and homicide, specifically, the homicide of young children. Assuming that abortions occurred when the family had insufficient resources for the birth, one could hypothesize that children would have been at higher risk of homicide if born into these circumstances. We examined 1960-1998 U.S. mortality data for children under 5 years of age using an interrupted time series design. The legalization of abortion was not associated with a sudden change in child homicide trends. It was, however, associated with a steady decrease in the homicides of toddlers (i.e., 1- to 4-year-olds) in subsequent years. Although in the predicted direction, the decrease in homicides of children under 1 year of age was not statistically significant. Competing explanations that could be examined in the data (e.g., changes in mortality classification) do not account for the findings

Study to determine experimentally the feasibility of new methods for improving thermal conductance of mechanical joints in a vacuum Summary research report, 8 Apr. - 30 Sep. 1966

Surface-plateauing techniques, and flexible surface membranes for improved thermal conductance of mechanical joints in vacuu

The Legalization of Abortion and Subsequent Youth Homicide: A Time Series Analysis

In this article, we examine the association between the legalization of abortion with the 1973 Roe v. Wade decision and youth homicide in the 1980s and 1990s. An interrupted time series design was used to examine the deaths of all U.S. 15- to 24-year-olds that were classified as homicides according to the International Classification of Diseases (codes E960-969) from 1970 to 1998. The legalization of abortion is associated over a decade later with a gradual reduction in the homicides of White and non-White young men. The effect on the homicides of young women is minimal. We conclude that the 1990s decline in the homicide of young men is statistically associated with the legalization of abortion. Findings are not consistent with several alternative explanations, such as changes in the crack cocaine drug market. It is almost inconceivable that in the United States of today, policies affecting the choice to have children would be justified as a means to control crime. Yet, if the legalization of abortion had this unintended effect, the full range of policy implications needs to be discussed

Hip Flexion Angles During Supine Range of Motion and Bodyweight Squats

International Journal of Exercise Science 14(1): 912-918, 2021. During the lowering phase of a squat, it has been observed that a posterior pelvic tilt (PPT) may occur when squatting to full depth. Research suggests that defaulting to compensatory movement strategies, such as PPT, during the squat may correlate with risk of lower extremity and trunk pathology. The purpose of this study was to examine hip flexion (HF) angles at the point when PPT occurs among three conditions: standard squats, heel raise squats, and supine passive HF; analyzing the differences in depth between standard and heel raise squats; and calculating differences in knee angles and ankle excursion between standard and heel raise squats. 28 participants performed bodyweight squats and underwent supine passive HF while outfitted with 32 retroreflective motion capture markers. Hip, knee, and ankle joint angles were extracted at the point of PPT. A one-way repeated measures ANOVA was used to determine differences in hip joint angles between conditions, and a paired sample t-test was used to compare knee angles, ankle excursion, and squat depth between standard and heel raise squats. HF angles at PPT remained unchanged across all conditions. However, significantly greater knee flexion, ankle excursion, and squat depth were observed in the heel raise squats compared to the standard squats. Results suggest that PPT is a compensatory movement that occurs as the femur compresses into the acetabulum once hip flexion has been exhausted

Modeling cancer genomic data in yeast reveals selection against ATM function during tumorigenesis

The DNA damage response (DDR) comprises multiple functions that collectively preserve genomic integrity and suppress tumorigenesis. The Mre11 complex and ATM govern a major axis of the DDR and several lines of evidence implicate that axis in tumor suppression. Components of the Mre11 complex are mutated in approximately five percent of human cancers. Inherited mutations of complex members cause severe chromosome instability syndromes, such as Nijmegen Breakage Syndrome, which is associated with strong predisposition to malignancy. And in mice, Mre11 complex mutations are markedly more susceptible to oncogene- induced carcinogenesis. The complex is integral to all modes of DNA double strand break (DSB) repair and is required for the activation of ATM to effect DNA damage signaling. To understand which functions of the Mre11 complex are important for tumor suppression, we undertook mining of cancer genomic data from the clinical sequencing program at Memorial Sloan Kettering Cancer Center, which includes the Mre11 complex among the 468 genes assessed. Twenty five mutations in MRE11 and RAD50 were modeled in S. cerevisiae and in vitro. The mutations were chosen based on recurrence and conservation between human and yeast. We found that a significant fraction of tumor-borne RAD50 and MRE11 mutations exhibited separation of function phenotypes wherein Tel1/ATM activation was severely impaired while DNA repair functions were mildly or not affected. At the molecular level, the gene products of RAD50 mutations exhibited defects in ATP binding and hydrolysis. The data reflect the importance of Rad50 ATPase activity for Tel1/ATM activation and suggest that inactivation of ATM signaling confers an advantage to burgeoning tumor cells

Dynamic optical lattices: two-dimensional rotating and accordion lattices for ultracold atoms

We demonstrate a novel experimental arrangement which rotates a 2D optical lattice at frequencies up to several kilohertz. Ultracold atoms in such a rotating lattice can be used for the direct quantum simulation of strongly correlated systems under large effective magnetic fields, allowing investigation of phenomena such as the fractional quantum Hall effect. Our arrangement also allows the periodicity of a 2D optical lattice to be varied dynamically, producing a 2D accordion lattice.Comment: 7 pages, 5 figures, final versio