dxz/yzd_{xz/yz} Orbital Subband Structures and Chiral Orbital Angular Momentum in the (001) Surface States of SrTiO3_3

We have performed angle resolved photoemission spectroscopy (ARPES) experiments on the surface states of SrTiO$_3$(001) using linearly and circularly polarized light to investigate the subband structures of out-of-plane $d_{xz/yz}$ orbitals and chiral orbital angular momentum (OAM). The data taken in the first Brillouin zone reveal new subbands for $d_{xz/yz}$ orbitals with Fermi wave vectors of 0.25 and 0.45 $\mathrm{\AA}^{-1}$ in addition to the previously reported ones. As a result, there are at least two subbands for all the Ti 3d t$_{2g}$ orbitals. Our circular dichroism ARPES data is suggestive of a chiral OAM structure in the surface states and may provide clues to the origin of the linear Rashba-like surface band splitting.Comment: 7 pages, 3 figures, Journal pape

Flow-Induced Voltage Generation Over Monolayer Graphene in the Presence of Herringbone Grooves

While flow-induced voltage over a graphene layer has been reported, its origin remains unclear. In our previous study, we suggested different mechanisms for different experimental configurations: phonon dragging effect for the parallel alignment and an enhanced out-of-plane phonon mode for the perpendicular alignment (Appl. Phys. Lett. 102:063116, 2011). In order to further examine the origin of flow-induced voltage, we introduced a transverse flow component by integrating staggered herringbone grooves in the microchannel. We found that the flow-induced voltage decreased significantly in the presence of herringbone grooves in both parallel and perpendicular alignments. These results support our previous interpretation

Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway.

YAP (Yes-associated protein) is a transcription co-activator in the Hippo tumour suppressor pathway and controls cell growth, tissue homeostasis and organ size. YAP is inhibited by the kinase Lats, which phosphorylates YAP to induce its cytoplasmic localization and proteasomal degradation. YAP induces gene expression by binding to the TEAD family transcription factors. Dysregulation of the Hippo-YAP pathway is frequently observed in human cancers. Here we show that cellular energy stress induces YAP phosphorylation, in part due to AMPK-dependent Lats activation, thereby inhibiting YAP activity. Moreover, AMPK directly phosphorylates YAP Ser 94, a residue essential for the interaction with TEAD, thus disrupting the YAP-TEAD interaction. AMPK-induced YAP inhibition can suppress oncogenic transformation of Lats-null cells with high YAP activity. Our study establishes a molecular mechanism and functional significance of AMPK in linking cellular energy status to the Hippo-YAP pathway

Cho Jihoon’s Korean Aesthetics: the Concept of ‘Meot’

Cho Jihoon’s aesthetics is based on the Confucian literati’s spirit, choesado, and on the Buddhist idea of non-duality. He presented the theory of meot, meaning taste originally, as a Korean-specific aesthetic category in his Study of Meot, where he synthesized the previously discussed theories of other scholars into twelve elements. Discussing the formal characteristics of works that have the aesthetic quality of meot, he took unrefinedness as basic, and cited diversity, eurhythmy, and curvature as its subtraits. Discussing the compositional power or method of expression that provokes meot, he took hyperstandard as basic, and the subtraits include maturity, distortion, and playfulness. Furthermore, he discussed meot as an emotion or idea that Koreans live with, where the most basic one is otiosity (impracticality), and assimilation, moderation, and optimism are its subtraits. Finally, he identified meot as the ultimate aesthetic state with pungryu, a lifestyle in harmony with Nature, which is originated from the ancient Silla period.

Experimental observation of hidden Berry curvature in inversion-symmetric bulk 2H-WSe2

We investigate the hidden Berry curvature in bulk 2H-WSe2 by utilizing the surface sensitivity of angle resolved photoemission (ARPES). The symmetry in the electronic structure of transition metal dichalcogenides is used to uniquely determine the local orbital angular momentum (OAM) contribution to the circular dichroism (CD) in ARPES. The extracted CD signals for the K and K' valleys are almost identical but their signs, which should be determined by the valley index, are opposite. In addition, the sign is found to be the same for the two spin-split bands, indicating that it is independent of spin state. These observed CD behaviors are what are expected from Berry curvature of a monolayer of WSe2. In order to see if CD-ARPES is indeed representative of hidden Berry curvature within a layer, we use tight binding analysis as well as density functional calculation to calculate the Berry curvature and local OAM of a monolayer WSe2. We find that measured CD-ARPES is approximately proportional to the calculated Berry curvature as well as local OAM, further supporting our interpretation.Comment: 6 pages, 3 figure

Three-dimensional visualization of choroidal vessels by using standard and ultra-high resolution scattering optical coherence angiography

Scattering optical coherence angiography (S-OCA) is a noninvasive imaging method that is based on the high-speed standard 800nm band spectral-domain optical coherence tomography (SD-OCT) and the ultra-high-resolution SD-OCT which has the axial resolution of 6.1 μm and 2.9 μm in tissue, respectively. In this paper, we have demonstrated the use of this method for in vivo human retinal imaging. A three-dimensional view of the choroidal vasculature was obtained by segmenting the choroidal vessels; this was done using intensity threshold based binarization at each depth plane relative to the retinal pigment epithelium. A vascular projection image was obtained by integrating the segmented choroidal vasculature. In order to assess the feasibility of the proposed method, we compared these images with those obtained using existing invasive methods such as fluorescein angiography and indocyanine green angiography. Clinically worthful images are obtained from the application of S-OCA to the agerelated macular degeneration and polypoidal choroidal vasculopathy.This paper was published in Optics Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-12-7538. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law

New Business Exercise: The Pop-Up Store Project

In this hands-on exercise, students develop and manage a successful retail pop-up store for one week in Tucson Mall in the city of Tucson. This is the final process in a two-semester project that involves the comprehensive business planning and execution process from idea generation, business planning, merchandise planning, investor pitch, vendor selection, product development, vendor selection and execution. Students work as teams to achieve maximum revenue and profits over a full week and, most importantly, develop a genuine understanding of the challenges of developing and executing a retail concept. The learning objectives of this year-long project are 1) to help students to understand how learning by doing in an ever-changing and unpredictable environment may have substantial advantages over traditional analysis, research, and business planning; 2) to find solutions for customers\u27 wants; 3) to execute an actual business with their own innovative products; 4) to explore the trade-offs that entrepreneurs face as they start a new business or launch a product or service; 5) to build team work, communication, and leadership skills

Quantum Neural Network Software Testing, Analysis, and Code Optimization for Advanced IoT Systems: Design, Implementation, and Visualization

This paper introduces a novel run-time testing, analysis, and code optimization (TACO) method for quantum neural network (QNN) software in advanced Internet-of-Things (IoT) systems, which visually presents the learning performance that is called a barren plateau. The run-time visual presentation of barren plateau situations is helpful for real-time quantum-based advanced IoT software testing because the software engineers can easily be aware of the training performances of QNN. Moreover, this tool is obviously useful for software engineers because it can intuitively guide them in designing and implementing high-accurate QNN-based advanced IoT software even if they are not familiar with quantum mechanics and quantum computing. Lastly, the proposed TACO is also capable of visual feedback because software engineers visually identify the barren plateau situations using tensorboard. In turn, they are also able to modify QNN structures based on the information

A Team-based Experiential Learning in Supply Chain Sourcing: Purchasing and Negotiation Exercises

This paper presents a web-hosted Google Sheet model of supply chain sourcing game focusing on negotiation activities which has been used in the classroom. The negotiation exercise was designed to place students in a position where they must make team based purchasing and selling decisions. The exercise was broken into three separate games. The first game is a group based on purchasing strategies. In this activity, they learn the basics of making purchasing decisions while considering demand, holding and ordering costs, and variable (tier based) pricing. The next two games are round based games. In the class, teams are formed (an even number) and half the teams are assigned to be a purchaser while the other half are suppliers in the first round. Each team must make decisions that will make them better off than other teams. Once the first round is complete, the teams switch roles with a different scenario and continue negotiating. The team with the most profit is the winner of the exercise. The purpose of this article is to describe the structure of the exercise, how we deliver it as a pedagogical game in our classes, and share this easy to apply activities that capture the dynamics of negotiation and the resulting benefits to supply to supply chain members