Modelling of networked measuring systems -- from white-box models to data based approaches

Mathematical modelling is at the core of metrology as it transforms raw measured data into useful measurement results. A model captures the relationship between the measurand and all relevant quantities on which the measurand depends, and is used to design measuring systems, analyse measured data, make inferences and predictions, and is the basis for evaluating measurement uncertainties. Traditional modelling approaches are typically analytical, for example, based on principles of physics. But with the increasing use of digital technologies, large sensor networks and powerful computing hardware, these traditional approaches are being replaced more and more by data-driven methods. This paradigm shift holds true in particular for the digital future of measurement in all spheres of our lives and the environment, where data provided by large and complex interconnected systems of sensors are to be analysed. Additionally, there is a requirement for existing guidelines and standards in metrology to take the paradigm shift into account. In this paper we lay the foundation for the development from traditional to data-driven modelling approaches. We identify key aspects from traditional modelling approaches and discuss their transformation to data-driven modelling

A Bayesian approach to information fusion for evaluating the measurement uncertainty,” in

Abstract -The Bayesian approach to uncertainty evaluation is a classical example for information fusion. It is based on both, the knowledge about the measuring process and the input quantities. Appropriate probability density functions for the input quantities may be obtained by utilizing the principle of maximum information entropy and the Bayes theorem. The knowledge about the measurement process is represented by the so-called model equation which forms the basis for the fusion of all involved input quantities. Compared to the ISO-GUM procedure, the Bayesian approach to uncertainty evaluation does not have any restriction related to nonlinearity and determination of confidence intervals

Grid Workflow Approach using the CELLmicrocosmos 2.2 MembraneEditor and UNICORE to commit and monitor GROMACS Jobs

Rubert S, Gamroth C, Krüger J, Sommer B. Grid Workflow Approach using the CELLmicrocosmos 2.2 MembraneEditor and UNICORE to commit and monitor GROMACS Jobs. In: Warzecha K-D, Packschies L, eds. CEUR Workshop Proceedings. Vol 826. CEUR-WS; 2012.Molecular dynamic simulations of membrane systems are an important method for the prediction and analysis of physicochemical properties. The CELLmicrocosmos 2.2 MembraneEditor (CmME) provides a comfortable workflow to generate lipid membranes with different conformations. While CmME is intended to generate molecular structures on desktop and mobile computers in a very short time, the atomic simulation of exported membranes needs external high performance computer resources. In this work, a first approach of a direct connection between CmME and a cluster running GROMACS using the Gridmiddleware UNICORE-6 is discussed

Intraindividual comparison of [68 Ga]-Ga-PSMA-11 and [18F]-F-PSMA-1007 in prostate cancer patients: a retrospective single-center analysis

Background!#!The analysis aimed to compare the radiotracers [!##!Methods!#!A retrospective analysis of 46 prostate cancer patients (median age: 71 years) who underwent consecutive [!##!Results!#!Differences in terms of miTNM stages in both studies occurred in nine of the 46 patients (19.6%). The miT stages differed in five patients (10.9%), the miN stages differed in three patients (6.5%), and different miM stages occurred only in one patient who was upstaged in [!##!Conclusion!#!In terms of miTNM staging, both tracers appeared widely exchangeable, as no tracer relevantly outperformed the other. The differences between the two tracers were far more common in presumable unspecific lesions than in malignant spots. A routinely performed two-tracer study could not be shown to be superior. Since it seems at least challenging for most nuclear medicine departments to provide both

Challenges and trends in manufacturing measurement technology – the “Industrie 4.0” concept

Strategic considerations and publications dealing with the future of industrial production are significantly influenced these days by the concept of “Industrie 4.0”. For this reason the field of measurement technology for industrial production must also tackle this concept when thinking about future trends and challenges in metrology. To this end, the Manufacturing Metrology Roadmap 2020 of the VDI/VDE Society for Measurement and Automatic Control (GMA) was published in 2011 (VDI/VDE-GMA, 2011; Imkamp et al., 2012). The content of this roadmap is reviewed and extended here, covering new developments in the field of the Industrie 4.0 concept and presented with expanded and updated content

Hygiene guideline for the planning, installation, and operation of ventilation and air-conditioning systems in health-care settings – Guideline of the German Society for Hospital Hygiene (DGKH)

Since the publication of the first “Hospital Hygiene Guideline for the implementation and operation of air conditioning systems (HVAC systems) in hospitals” () in 2002, it was necessary due to the increase in knowledge, new regulations, improved air-conditioning systems and advanced test methods to revise the guideline. Based on the description of the basic features of ventilation concepts, its hygienic test and the usage-based requirements for ventilation, the DGKH section “Ventilation and air conditioning technology” attempts to provide answers for the major air quality issues in the planning, design and the hygienically safe operation of HVAC systems in rooms of health care