4,489 research outputs found

    A computer program for the design and analysis of low-speed airfoils

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    A conformal mapping method for the design of airfoils with prescribed velocity distribution characteristics, a panel method for the analysis of the potential flow about given airfoils, and a boundary layer method have been combined. With this combined method, airfoils with prescribed boundary layer characteristics can be designed and airfoils with prescribed shapes can be analyzed. All three methods are described briefly. The program and its input options are described. A complete listing is given as an appendix

    A computer program for the design and analysis of low-speed airfoils, supplement

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    Three new options were incorporated into an existing computer program for the design and analysis of low speed airfoils. These options permit the analysis of airfoils having variable chord (variable geometry), a boundary layer displacement iteration, and the analysis of the effect of single roughness elements. All three options are described in detail and are included in the FORTRAN IV computer program

    An exploratory investigation of the effect of a plastic coating on the profile drag of a practical-metal-construction sailplane airfoil

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    The Langley low-turbulence pressure tunnel to determine the effect of a plastic coating on the profile drag of a practical-metal-construction sailplane airfoil was investigated. The model was tested with three surface configurations: (1) filled, painted, and sanded smooth; (2) rough bare metal; and (3) plastic-coated. The results are compared with data for the design airfoil (Wortmann FX 67-K-170/17) from another low-turbulence wind tunnel. The investigation was conducted at Reynolds numbers based on airfoil chord of 1.1 x 10 to the 6th power, 2.2 x 10 to the 6th power, and 3.3 x 10 to the 6th power at a Mach number of 0.10

    The design of an airfoil for a high-altitude, long-endurance remotely piloted vehicle

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    Airfoil design efforts are studied. The importance of integrating airfoil and aircraft designs was demonstrated. Realistic airfoil data was provided to aid future high altitude, long endurance aircraft preliminary design. Test cases were developed for further validation of the Eppler program. Boundary layer, not pressure distribution or shape, was designed. Substantial improvement was achieved in vehicle performance through mission specific airfoil designed utilizing the multipoint capability of the Eppler program

    Low-speed aerodynamic characteristics of a 13-percent-thick airfoil section designed for general aviation applications

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    Wind-tunnel tests were conducted to determine the low-speed section characteristics of a 13 percent-thick airfoil designed for general aviation applications. The results were compared with NACA 12 percent-thick sections and with the 17 percent-thick NASA airfoil. The tests were conducted ovar a Mach number range from 0.10 to 0.35. Chord Reynolds numbers varied from about 2,000,000 to 9,000,000

    Sustainability implications of carbon delivery in microalgae cultivation for the production of biofuel

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    2018 Summer.Includes bibliographical references.Supplementation of carbon is critical for high productivity cultivation of most microalgae. Moreover, using microalgae for atmospheric CO2 mitigation to combat climate change is promising, as waste sources and atmospheric CO2 can be utilized to produce useful products. The challenge is developing technologies, processes, and strategies that utilize carbon effectively such that the overall system is sustainable. Through engineering systems modeling combined with techno-economic and life-cycle assessments, this study examined the implications of various delivery methods of carbon to a production-scale algal biorefinery. Five primary carbon sources were considered: atmospheric CO2; CO2 from direct chemical or power plant waste emissions; CO2 that has been concentrated from waste sources and compressed; inorganic carbon in the form of sodium bicarbonate salt; and organic carbon in the form of cellulosic sugars derived from corn stover. Each source was evaluated assuming co-location as well as pipeline transportation up to 100 km. The sensitivity of results to carbon utilization efficiency was also considered. Sustainability results indicate that economics are more prohibitive than energy and emissions. Of the scenarios evaluated, only two met both the economic and environmental criteria of contributing less than $0.50 GGE−1 and 20 gCO2-eq MJ−1 to the overall system, respectively: uncompressed, pure sources of gaseous CO2 with pipeline transportation of 40 km or less; and compressed, supercritical CO2 from pure sources for pipeline transportation up to 100 km. The scalability of algal biofuels based on these results shows carbon to be the limiting nutrient in an algal biorefinery with a total US production capability of 360 million gallons of fuel per year

    An airfoil for general aviation applications

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    A new airfoil, the NLF(1)-0115, has been recently designed at the NASA Langley Research Center for use in general-aviation applications. During the development of this airfoil, special emphasis was placed on experiences and observations gleaned from other successful general-aviation airfoils. For example, the flight lift-coefficient range is the same as that of the turbulent-flow NACA 23015 airfoil. Also, although beneficial for reducing drag and having large amounts of lift, the NLF(1)-0115 avoids the use of aft loading which can lead to large stick forces if utilized on portions of the wing having ailerons. Furthermore, not using aft loading eliminates the concern that the high pitching-moment coefficient generated by such airfoils can result in large trim drags if cruise flaps are not employed. The NASA NLF(1)-0115 has a thickness of 15 percent. It is designed primarily for general-aviation aircraft with wing loadings of 718 to 958 N/sq m (15 to 20 lb/sq ft). Low profile drag as a result of laminar flow is obtained over the range from c sub l = 0.1 and R = 9x10(exp 6) (the cruise condition) to c sub l = 0.6 and R = 4 x 10(exp 6) (the climb condition). While this airfoil can be used with flaps, it is designed to achieve c(sub l, max) = 1.5 at R = 2.6 x 10(exp 6) without flaps. The zero-lift pitching moment is held at c sub m sub o = 0.055. The hinge moment for a .20c aileron is fixed at a value equal to that of the NACA 63 sub 2-215 airfoil, c sub h = 0.00216. The loss in c (sub l, max) due to leading edge roughness, rain, or insects at R = 2.6 x 10 (exp 6) is 11 percent as compared with 14 percent for the NACA 23015

    An Exploratory Investigation of the Effect of Plastic Coating on the Profile Drag of a Practical-Metal-Construction Sailplane Airfoil

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    An exploratory investigation was performed in the Langley low-turbulence pressure tunnel to determine the effect of a plastic coating on the profile drage of a practical-metal-construction sailplaine airfoil. The mode was tested with three surface configurations: (1) filled, painted, and sanded smooth; (2) rough bare metal; and (3) plastic-coated. The investigation was conducted at Reynolds numbers based on airfoil chord of 1,100,000, 2,200,000, and 3,300,000 at a constant Mach number of 0.10. The results indicate that, at all three Reynolds numbers, the order of the drag values of the three surface configurations, starting with the highest drag, was: filled, painted, and sanded smooth; rough bare metal; and plastic-coated

    p53 directly regulates the glycosidase FUCA1 to promote chemotherapy-induced cell death

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    p53 is a central factor in tumor suppression as exemplified by its frequent loss in human cancer. p53 exerts its tumor suppressive effects in multiple ways, but the ability to invoke the eradication of damaged cells by programmed cell death is considered a key factor. The ways in which p53 promotes cell death can involve direct activation or engagement of the cell death machinery, or can be via indirect mechanisms, for example though regulation of ER stress and autophagy. We present here another level of control in p53-mediated tumor suppression by showing that p53 activates the glycosidase, FUCA1, a modulator of N-linked glycosylation. We show that p53 transcriptionally activates FUCA1 and that p53 modulates fucosidase activity via FUCA1 up-regulation. Importantly, we also report that chemotherapeutic drugs induce FUCA1 and fucosidase activity in a p53-dependent manner. In this context, while we found that over-expression of FUCA1 does not induce cell death, RNAi-mediated knockdown of endogenous FUCA1 significantly attenuates p53-dependent, chemotherapy-induced apoptotic death. In summary, these findings add an additional component to p53s tumor suppressive response and highlight another mechanism by which the tumor suppressor controls programmed cell death that could potentially be exploited for cancer therapy
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